| Gene Symbol | AGR3 |
| Entrez Gene ID | 155465 |
| Full Name | anterior gradient 3, protein disulphide isomerase family member |
| Synonyms | AG-3,AG3,BCMP11,HAG3,PDIA18,hAG-3 |
| General protein information |
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| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This gene is expressed in ciliated airway epithelial cells and, in mouse, plays a role in ciliary beat frequency in multiciliated cells. This gene is also over-expressed in breast, ovarian, and prostrate cancers. [provided by RefSeq, Dec 2016]. |
| Disorder MIM: |
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