TMEM52B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TMEM52B
Entrez Gene ID	120939
Full Name	transmembrane protein 52B
Synonyms	C12orf59
General protein information	Preferred Names transmembrane protein 52B Names transmembrane protein 52B
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12p13.2

mRNA and Protein(s)

mRNA	Protein	Name
XM_006719029.3	XP_006719092.1	transmembrane protein 52B isoform X1
XM_006719029.2	XP_006719092.1	transmembrane protein 52B isoform X1
NM_001079815.1	NP_001073283.1	transmembrane protein 52B isoform 2 precursor
NM_153022.4	NP_694567.1	transmembrane protein 52B isoform 1
NM_153022.3	NP_694567.1	transmembrane protein 52B isoform 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TMEM52B	XP_003954455.1
Rattus norvegicus (Norway rat)	Tmem52b	NP_001103030.1
Gallus gallus (chicken)	C1H12ORF59	XP_424100.3
Xenopus tropicalis (tropical clawed frog)	tmem52b	XP_004915862.1
Bos taurus (cattle)	TMEM52B	NP_001095995.1
Homo sapiens (human)	TMEM52B	NP_001073283.1
Canis lupus familiaris (dog)	TMEM52B	XP_005637219.1
Mus musculus (house mouse)	Tmem52b	NP_001074655.1

Gene Ontology
Bibliography

Related articles in PubMed

A positive feedback loop consisting of C12orf59/NF-κB/CDH11 promotes gastric cancer invasion and metastasis.
Zhang JX, He WL, Feng ZH, Chen DL, Gao Y, He Y, Qin K, Zheng ZS, Chen C, Weng HW, Yun M, Ye S, Xu RH, Xie D
Journal of experimental & clinical cancer research : CR38(1)164(2019 Apr)

Down-regulation of C12orf59 is associated with a poor prognosis and VHL mutations in renal cell carcinoma.
Xie J, Zhu C, Wu J, Li C, Luo L, Xia L, Li X, Gui Y, Cai Z, Li Z
Oncotarget7(6)6824-34(2016 Feb)

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TMEM52B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TMEM52B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09787	NM_153022.4 Latest version!	Homo sapiens transmembrane protein 52B (TMEM52B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu11769	NM_001079815.1 Latest version!	Homo sapiens transmembrane protein 52B (TMEM52B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu11769	XM_006719029.3 Latest version!	Homo sapiens transmembrane protein 52B (TMEM52B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
View Old Accession Versions >>
OHu11769	XM_006719029.2	Homo sapiens transmembrane protein 52B (TMEM52B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu09787	NM_153022.3	Homo sapiens transmembrane protein 52B (TMEM52B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TMEM52B ( XM_006719029.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006719092.1 Homo sapiens transmembrane protein 52B (TMEM52B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu11769
Clone ID Related Accession (Same CDS sequence)	XM_006719029.3 , XM_006719029.2 , NM_001079815.1
Accession Version	XM_006719029.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 552bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	transmembrane protein 52B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_006719029.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAGTCC GAGTTCATGT CGTGGCGGCC TCAGCCCTGC TGTATTTCAT CCTGCTTTCT 
GGGACGAGAT GTGAGGAAAA CTGTGGTAAT CCTGAACATT GCCTGACCAC AGACTGGGTA 
CATCTCTGGT ATATATGGTT GCTAGTGGTA ATTGGCGCGC TGCTTCTCCT GTGTGGCCTG 
ACGTCCCTGT GCTTCCGCTG CTGCTGTCTG AGCCGCCAGC AAAATGGGGA AGATGGGGGC 
CCACCACCCT GTGAAGTGAC CGTCATTGCT TTCGATCACG ACAGCACTCT CCAGAGCACT 
ATCACATCTC TGCAGTCGGT GTTTGGCCCT GCAGCTCGGA GGATCCTGGC TGTGGCTCAC 
TCCCACAGCT CCCTGGGCCA GCTGCCCTCC TCTTTGGACA CCCTCCCAGG GTATGAAGAA 
GCTCTTCACA TGAGTCGCTT CACAGTAGCC ATGTGCGGGC AGAAAGCACC TGATCTACCC 
CCAGTACCTG AAGAAAAGCA GCTGCCTCCA ACAGAGAAGG AGTCGACTCG AATAGTTGAC 
TCTTGGAACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006719092.1
CDS	618..1169
Translation	MGVRVHVVAASALLYFILLSGTRCEENCGNPEHCLTTDWVHLWYIWLLVVIGALLLLCGLTSLCFRCCCLSRQQNGEDGGPPPCEVTVIAFDHDSTLQSTITSLQSVFGPAARRILAVAHSHSSLGQLPSSLDTLPGYEEALHMSRFTVAMCGQKAPDLPPVPEEKQLPPTEKESTRIVDSWN

Target ORF information:

RefSeq Version	XM_006719029.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 52B (TMEM52B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006719029.2

ORF Insert Sequence:

ATGGGAGTCC GAGTTCATGT CGTGGCGGCC TCAGCCCTGC TGTATTTCAT CCTGCTTTCT 
GGGACGAGAT GTGAGGAAAA CTGTGGTAAT CCTGAACATT GCCTGACCAC AGACTGGGTA 
CATCTCTGGT ATATATGGTT GCTAGTGGTA ATTGGCGCGC TGCTTCTCCT GTGTGGCCTG 
ACGTCCCTGT GCTTCCGCTG CTGCTGTCTG AGCCGCCAGC AAAATGGGGA AGATGGGGGC 
CCACCACCCT GTGAAGTGAC CGTCATTGCT TTCGATCACG ACAGCACTCT CCAGAGCACT 
ATCACATCTC TGCAGTCGGT GTTTGGCCCT GCAGCTCGGA GGATCCTGGC TGTGGCTCAC 
TCCCACAGCT CCCTGGGCCA GCTGCCCTCC TCTTTGGACA CCCTCCCAGG GTATGAAGAA 
GCTCTTCACA TGAGTCGCTT CACAGTAGCC ATGTGCGGGC AGAAAGCACC TGATCTACCC 
CCAGTACCTG AAGAAAAGCA GCTGCCTCCA ACAGAGAAGG AGTCGACTCG AATAGTTGAC 
TCTTGGAACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM52B ( NM_153022.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_694567.1 Homo sapiens transmembrane protein 52B (TMEM52B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu09787
Clone ID Related Accession (Same CDS sequence)	NM_153022.4 , NM_153022.3
Accession Version	NM_153022.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 492bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565539200000
Organism	Homo sapiens(human)
Product	transmembrane protein 52B isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY358845.1, AC115676.1 and BE301029.1. On Jun 2, 2019 this sequence version replaced NM_153022.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the shorter isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK055728.1, AY358845.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2142853 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGTGGC GGCCTCAGCC CTGCTGTATT TCATCCTGTT GCCTGACCAC AGACTGGGTA 
CATCTCTGGT ATATATGGTT GCTAGTGGTA ATTGGCGCGC TGCTTCTCCT GTGTGGCCTG 
ACGTCCCTGT GCTTCCGCTG CTGCTGTCTG AGCCGCCAGC AAAATGGGGA AGATGGGGGC 
CCACCACCCT GTGAAGTGAC CGTCATTGCT TTCGATCACG ACAGCACTCT CCAGAGCACT 
ATCACATCTC TGCAGTCGGT GTTTGGCCCT GCAGCTCGGA GGATCCTGGC TGTGGCTCAC 
TCCCACAGCT CCCTGGGCCA GCTGCCCTCC TCTTTGGACA CCCTCCCAGG GTATGAAGAA 
GCTCTTCACA TGAGTCGCTT CACAGTAGCC ATGTGCGGGC AGAAAGCACC TGATCTACCC 
CCAGTACCTG AAGAAAAGCA GCTGCCTCCA ACAGAGAAGG AGTCGACTCG AATAGTTGAC 
TCTTGGAACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_694567.1
CDS	560..1051
Translation	MSWRPQPCCISSCCLTTDWVHLWYIWLLVVIGALLLLCGLTSLCFRCCCLSRQQNGEDGGPPPCEVTVIAFDHDSTLQSTITSLQSVFGPAARRILAVAHSHSSLGQLPSSLDTLPGYEEALHMSRFTVAMCGQKAPDLPPVPEEKQLPPTEKESTRIVDSWN

Target ORF information:

RefSeq Version	NM_153022.4
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 52B (TMEM52B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153022.4

ORF Insert Sequence:

ATGTCGTGGC GGCCTCAGCC CTGCTGTATT TCATCCTGTT GCCTGACCAC AGACTGGGTA 
CATCTCTGGT ATATATGGTT GCTAGTGGTA ATTGGCGCGC TGCTTCTCCT GTGTGGCCTG 
ACGTCCCTGT GCTTCCGCTG CTGCTGTCTG AGCCGCCAGC AAAATGGGGA AGATGGGGGC 
CCACCACCCT GTGAAGTGAC CGTCATTGCT TTCGATCACG ACAGCACTCT CCAGAGCACT 
ATCACATCTC TGCAGTCGGT GTTTGGCCCT GCAGCTCGGA GGATCCTGGC TGTGGCTCAC 
TCCCACAGCT CCCTGGGCCA GCTGCCCTCC TCTTTGGACA CCCTCCCAGG GTATGAAGAA 
GCTCTTCACA TGAGTCGCTT CACAGTAGCC ATGTGCGGGC AGAAAGCACC TGATCTACCC 
CCAGTACCTG AAGAAAAGCA GCTGCCTCCA ACAGAGAAGG AGTCGACTCG AATAGTTGAC 
TCTTGGAACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM52B ( NM_153022.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_694567.1 Homo sapiens transmembrane protein 52B (TMEM52B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu09787
Clone ID Related Accession (Same CDS sequence)	NM_153022.4 , NM_153022.3
Accession Version	NM_153022.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 492bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1530201600000
Organism	Homo sapiens(human)
Product	transmembrane protein 52B isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA621425.1, AY358845.1, AC115676.1 and BE301029.1. On Nov 8, 2013 this sequence version replaced NM_153022.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the shorter isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AY358845.1, AK055728.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2142853 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGTGGC GGCCTCAGCC CTGCTGTATT TCATCCTGTT GCCTGACCAC AGACTGGGTA 
CATCTCTGGT ATATATGGTT GCTAGTGGTA ATTGGCGCGC TGCTTCTCCT GTGTGGCCTG 
ACGTCCCTGT GCTTCCGCTG CTGCTGTCTG AGCCGCCAGC AAAATGGGGA AGATGGGGGC 
CCACCACCCT GTGAAGTGAC CGTCATTGCT TTCGATCACG ACAGCACTCT CCAGAGCACT 
ATCACATCTC TGCAGTCGGT GTTTGGCCCT GCAGCTCGGA GGATCCTGGC TGTGGCTCAC 
TCCCACAGCT CCCTGGGCCA GCTGCCCTCC TCTTTGGACA CCCTCCCAGG GTATGAAGAA 
GCTCTTCACA TGAGTCGCTT CACAGTAGCC ATGTGCGGGC AGAAAGCACC TGATCTACCC 
CCAGTACCTG AAGAAAAGCA GCTGCCTCCA ACAGAGAAGG AGTCGACTCG AATAGTTGAC 
TCTTGGAACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_694567.1
CDS	634..1125
Translation	MSWRPQPCCISSCCLTTDWVHLWYIWLLVVIGALLLLCGLTSLCFRCCCLSRQQNGEDGGPPPCEVTVIAFDHDSTLQSTITSLQSVFGPAARRILAVAHSHSSLGQLPSSLDTLPGYEEALHMSRFTVAMCGQKAPDLPPVPEEKQLPPTEKESTRIVDSWN

Target ORF information:

RefSeq Version	NM_153022.3
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 52B (TMEM52B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153022.3

ORF Insert Sequence:

ATGTCGTGGC GGCCTCAGCC CTGCTGTATT TCATCCTGTT GCCTGACCAC AGACTGGGTA 
CATCTCTGGT ATATATGGTT GCTAGTGGTA ATTGGCGCGC TGCTTCTCCT GTGTGGCCTG 
ACGTCCCTGT GCTTCCGCTG CTGCTGTCTG AGCCGCCAGC AAAATGGGGA AGATGGGGGC 
CCACCACCCT GTGAAGTGAC CGTCATTGCT TTCGATCACG ACAGCACTCT CCAGAGCACT 
ATCACATCTC TGCAGTCGGT GTTTGGCCCT GCAGCTCGGA GGATCCTGGC TGTGGCTCAC 
TCCCACAGCT CCCTGGGCCA GCTGCCCTCC TCTTTGGACA CCCTCCCAGG GTATGAAGAA 
GCTCTTCACA TGAGTCGCTT CACAGTAGCC ATGTGCGGGC AGAAAGCACC TGATCTACCC 
CCAGTACCTG AAGAAAAGCA GCTGCCTCCA ACAGAGAAGG AGTCGACTCG AATAGTTGAC 
TCTTGGAACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM52B ( NM_001079815.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001073283.1 Homo sapiens transmembrane protein 52B (TMEM52B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu11769
Clone ID Related Accession (Same CDS sequence)	XM_006719029.3 , XM_006719029.2 , NM_001079815.1
Accession Version	NM_001079815.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 552bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565539200000
Organism	Homo sapiens(human)
Product	transmembrane protein 52B isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA156941.1, AY358845.1, AC115676.1 and BE301029.1. On Nov 8, 2013 this sequence version replaced XM_005253298.1. Transcript Variant: This variant (2) differs in the 5' UTR, contains an alternate exon in the 5' coding region, and initiates translation from an alternate upstream start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is longer than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.227337.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142853, SAMEA2153307 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGAGTCC GAGTTCATGT CGTGGCGGCC TCAGCCCTGC TGTATTTCAT CCTGCTTTCT 
GGGACGAGAT GTGAGGAAAA CTGTGGTAAT CCTGAACATT GCCTGACCAC AGACTGGGTA 
CATCTCTGGT ATATATGGTT GCTAGTGGTA ATTGGCGCGC TGCTTCTCCT GTGTGGCCTG 
ACGTCCCTGT GCTTCCGCTG CTGCTGTCTG AGCCGCCAGC AAAATGGGGA AGATGGGGGC 
CCACCACCCT GTGAAGTGAC CGTCATTGCT TTCGATCACG ACAGCACTCT CCAGAGCACT 
ATCACATCTC TGCAGTCGGT GTTTGGCCCT GCAGCTCGGA GGATCCTGGC TGTGGCTCAC 
TCCCACAGCT CCCTGGGCCA GCTGCCCTCC TCTTTGGACA CCCTCCCAGG GTATGAAGAA 
GCTCTTCACA TGAGTCGCTT CACAGTAGCC ATGTGCGGGC AGAAAGCACC TGATCTACCC 
CCAGTACCTG AAGAAAAGCA GCTGCCTCCA ACAGAGAAGG AGTCGACTCG AATAGTTGAC 
TCTTGGAACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073283.1
CDS	348..899
Translation	MGVRVHVVAASALLYFILLSGTRCEENCGNPEHCLTTDWVHLWYIWLLVVIGALLLLCGLTSLCFRCCCLSRQQNGEDGGPPPCEVTVIAFDHDSTLQSTITSLQSVFGPAARRILAVAHSHSSLGQLPSSLDTLPGYEEALHMSRFTVAMCGQKAPDLPPVPEEKQLPPTEKESTRIVDSWN

Target ORF information:

RefSeq Version	NM_001079815.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 52B (TMEM52B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001079815.1

ORF Insert Sequence:

ATGGGAGTCC GAGTTCATGT CGTGGCGGCC TCAGCCCTGC TGTATTTCAT CCTGCTTTCT 
GGGACGAGAT GTGAGGAAAA CTGTGGTAAT CCTGAACATT GCCTGACCAC AGACTGGGTA 
CATCTCTGGT ATATATGGTT GCTAGTGGTA ATTGGCGCGC TGCTTCTCCT GTGTGGCCTG 
ACGTCCCTGT GCTTCCGCTG CTGCTGTCTG AGCCGCCAGC AAAATGGGGA AGATGGGGGC 
CCACCACCCT GTGAAGTGAC CGTCATTGCT TTCGATCACG ACAGCACTCT CCAGAGCACT 
ATCACATCTC TGCAGTCGGT GTTTGGCCCT GCAGCTCGGA GGATCCTGGC TGTGGCTCAC 
TCCCACAGCT CCCTGGGCCA GCTGCCCTCC TCTTTGGACA CCCTCCCAGG GTATGAAGAA 
GCTCTTCACA TGAGTCGCTT CACAGTAGCC ATGTGCGGGC AGAAAGCACC TGATCTACCC 
CCAGTACCTG AAGAAAAGCA GCTGCCTCCA ACAGAGAAGG AGTCGACTCG AATAGTTGAC 
TCTTGGAACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM52B ( XM_006719029.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006719092.1 Homo sapiens transmembrane protein 52B (TMEM52B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu11769
Clone ID Related Accession (Same CDS sequence)	XM_006719029.3 , XM_006719029.2 , NM_001079815.1
Accession Version	XM_006719029.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 552bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	transmembrane protein 52B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_006719029.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAGTCC GAGTTCATGT CGTGGCGGCC TCAGCCCTGC TGTATTTCAT CCTGCTTTCT 
GGGACGAGAT GTGAGGAAAA CTGTGGTAAT CCTGAACATT GCCTGACCAC AGACTGGGTA 
CATCTCTGGT ATATATGGTT GCTAGTGGTA ATTGGCGCGC TGCTTCTCCT GTGTGGCCTG 
ACGTCCCTGT GCTTCCGCTG CTGCTGTCTG AGCCGCCAGC AAAATGGGGA AGATGGGGGC 
CCACCACCCT GTGAAGTGAC CGTCATTGCT TTCGATCACG ACAGCACTCT CCAGAGCACT 
ATCACATCTC TGCAGTCGGT GTTTGGCCCT GCAGCTCGGA GGATCCTGGC TGTGGCTCAC 
TCCCACAGCT CCCTGGGCCA GCTGCCCTCC TCTTTGGACA CCCTCCCAGG GTATGAAGAA 
GCTCTTCACA TGAGTCGCTT CACAGTAGCC ATGTGCGGGC AGAAAGCACC TGATCTACCC 
CCAGTACCTG AAGAAAAGCA GCTGCCTCCA ACAGAGAAGG AGTCGACTCG AATAGTTGAC 
TCTTGGAACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006719092.1
CDS	615..1166
Translation	MGVRVHVVAASALLYFILLSGTRCEENCGNPEHCLTTDWVHLWYIWLLVVIGALLLLCGLTSLCFRCCCLSRQQNGEDGGPPPCEVTVIAFDHDSTLQSTITSLQSVFGPAARRILAVAHSHSSLGQLPSSLDTLPGYEEALHMSRFTVAMCGQKAPDLPPVPEEKQLPPTEKESTRIVDSWN

Target ORF information:

RefSeq Version	XM_006719029.3
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 52B (TMEM52B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006719029.3

ORF Insert Sequence:

ATGGGAGTCC GAGTTCATGT CGTGGCGGCC TCAGCCCTGC TGTATTTCAT CCTGCTTTCT 
GGGACGAGAT GTGAGGAAAA CTGTGGTAAT CCTGAACATT GCCTGACCAC AGACTGGGTA 
CATCTCTGGT ATATATGGTT GCTAGTGGTA ATTGGCGCGC TGCTTCTCCT GTGTGGCCTG 
ACGTCCCTGT GCTTCCGCTG CTGCTGTCTG AGCCGCCAGC AAAATGGGGA AGATGGGGGC 
CCACCACCCT GTGAAGTGAC CGTCATTGCT TTCGATCACG ACAGCACTCT CCAGAGCACT 
ATCACATCTC TGCAGTCGGT GTTTGGCCCT GCAGCTCGGA GGATCCTGGC TGTGGCTCAC 
TCCCACAGCT CCCTGGGCCA GCTGCCCTCC TCTTTGGACA CCCTCCCAGG GTATGAAGAA 
GCTCTTCACA TGAGTCGCTT CACAGTAGCC ATGTGCGGGC AGAAAGCACC TGATCTACCC 
CCAGTACCTG AAGAAAAGCA GCTGCCTCCA ACAGAGAAGG AGTCGACTCG AATAGTTGAC 
TCTTGGAACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A positive feedback loop consisting of C12orf59/NF-κB/CDH11 promotes gastric cancer invasion and metastasis.
Journal of experimental & clinical cancer research : CR38(1)164(2019 Apr)
Zhang JX,He WL,Feng ZH,Chen DL,Gao Y,He Y,Qin K,Zheng ZS,Chen C,Weng HW,Yun M,Ye S,Xu RH,Xie D

Down-regulation of C12orf59 is associated with a poor prognosis and VHL mutations in renal cell carcinoma.
Oncotarget7(6)6824-34(2016 Feb)
Xie J,Zhu C,Wu J,Li C,Luo L,Xia L,Li X,Gui Y,Cai Z,Li Z

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)
Gonzales PA,Pisitkun T,Hoffert JD,Tchapyjnikov D,Star RA,Kleta R,Wang NS,Knepper MA

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TMEM52B cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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