GBP4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GBP4
Entrez Gene ID	115361
Full Name	guanylate binding protein 4
Synonyms	Mpa2
General protein information	Preferred Names guanylate binding protein 4 Names guanylate-binding protein 4 GBP-4 GTP-binding protein 4 guanine nucleotide-binding protein 4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p22.2
Summary	Guanylate-binding proteins, such as GBP4, are induced by interferon and hydrolyze GTP to both GDP and GMP (Vestal, 2005 [PubMed 16108726]).[supplied by OMIM, Dec 2008].
Disorder MIM:	612466

mRNA and Protein(s)

mRNA	Protein	Name
NM_052941.4	NP_443173.2	guanylate-binding protein 4
NM_052941.5	NP_443173.2	guanylate-binding protein 4

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	LOC100496810	XP_002942120.2
Pan troglodytes (chimpanzee)	GBP4	XP_001149136.1
Mus musculus (house mouse)	Gbp3	NP_061204.3
Homo sapiens (human)	GBP4	NP_443173.2
Rattus norvegicus (Norway rat)	Gbp4	XP_227762.6

Gene Ontology
Bibliography

Related articles in PubMed

Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner.
Britzen-Laurent N, Bauer M, Berton V, Fischer N, Syguda A, Reipschläger S, Naschberger E, Herrmann C, Stürzl M
PloS one5(12)e14246(2010 Dec)

New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
Genes and immunity11(3)232-8(2010 Apr)

Unique features of different members of the human guanylate-binding protein family.
Tripal P, Bauer M, Naschberger E, Mörtinger T, Hohenadl C, Cornali E, Thurau M, Stürzl M
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research27(1)44-52(2007 Jan)

In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters.
Olszewski MA, Gray J, Vestal DJ
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research26(5)328-52(2006 May)

The guanylate-binding proteins (GBPs): proinflammatory cytokine-induced members of the dynamin superfamily with unique GTPase activity.
Vestal DJ
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research25(8)435-43(2005 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following GBP4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GBP4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu05592	NM_052941.5 Latest version!	Homo sapiens guanylate binding protein 4 (GBP4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$307.30 $439.00
View Old Accession Versions >>
OHu05592	NM_052941.4	Homo sapiens guanylate binding protein 4 (GBP4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GBP4 ( NM_052941.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_443173.2 Homo sapiens guanylate binding protein 4 (GBP4), mRNA.

Price & Availability↑

CloneID	OHu05592
Clone ID Related Accession (Same CDS sequence)	NM_052941.4 , NM_052941.5
Accession Version	NM_052941.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1923bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506787200000
Organism	Homo sapiens(human)
Product	guanylate-binding protein 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC008421.1, AF288814.1, BC070055.1, AC104459.2 and CA309701.1. On Aug 29, 2008 this sequence version replaced NM_052941.3. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.167664.1, SRR1803613.112887.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGGTGAGA GAACTCTTCA CGCTGCAGTG CCCACACCAG GTTATCCAGA ATCTGAATCC 
ATCATGATGG CCCCCATTTG TCTAGTGGAA AACCAGGAAG AGCAGCTGAC AGTGAATTCA 
AAGGCATTAG AGATTCTTGA CAAGATTTCT CAGCCCGTGG TGGTGGTGGC CATTGTAGGG 
CTATACCGCA CAGGAAAATC CTATCTCATG AATCGTCTTG CAGGAAAGCG CAATGGCTTC 
CCTCTGGGCT CCACGGTGCA GTCTGAAACT AAGGGCATCT GGATGTGGTG TGTGCCCCAC 
CTCTCTAAGC CAAACCACAC CCTGGTCCTT CTGGACACCG AGGGCCTGGG CGATGTAGAA 
AAGAGTAACC CTAAGAATGA CTCGTGGATC TTTGCCCTGG CTGTGCTTCT AAGCAGCAGC 
TTTGTCTATA ACAGCGTGAG CACCATCAAC CACCAGGCCC TGGAGCAGCT GCACTATGTG 
ACTGAGCTAG CAGAGCTAAT CAGGGCAAAA TCCTGCCCCA GACCTGATGA AGCTGAGGAC 
TCCAGCGAGT TTGCGAGTTT CTTTCCAGAC TTTATTTGGA CTGTTCGGGA TTTTACCCTG 
GAGCTAAAGT TAGATGGAAA CCCCATCACA GAAGATGAGT ACCTGGAGAA TGCCTTGAAG 
CTGATTCCAG GCAAGAATCC CAAAATTCAA AATTCAAACA TGCCTAGAGA GTGTATCAGG 
CATTTCTTCC GAAAACGGAA GTGCTTTGTC TTTGACCGGC CTACAAATGA CAAGCAATAT 
TTAAATCATA TGGACGAAGT GCCAGAAGAA AATCTGGAAA GGCATTTCCT TATGCAATCA 
GACAACTTCT GTTCTTATAT CTTCACCCAT GCAAAGACCA AGACCCTGAG AGAGGGAATC 
ATTGTCACTG GAAAGCGGCT GGGGACTCTG GTGGTGACTT ATGTAGATGC CATCAACAGT 
GGAGCAGTAC CTTGTCTGGA GAATGCAGTG ACAGCACTGG CCCAGCTTGA GAACCCAGCG 
GCTGTGCAGA GGGCAGCCGA CCACTATAGC CAGCAGATGG CCCAGCAACT GAGGCTCCCC 
ACAGACACGC TCCAGGAGCT GCTGGACGTG CATGCAGCCT GTGAGAGGGA AGCCATTGCA 
GTCTTCATGG AGCACTCCTT CAAGGATGAA AACCATGAAT TCCAGAAGAA GCTTGTGGAC 
ACCATAGAGA AAAAGAAGGG AGACTTTGTG CTGCAGAATG AAGAGGCATC TGCCAAATAT 
TGCCAGGCTG AGCTTAAGCG GCTTTCAGAG CACCTGACAG AAAGCATTTT GAGAGGAATT 
TTCTCTGTTC CTGGAGGACA CAATCTCTAC TTAGAAGAAA AGAAACAGGT TGAGTGGGAC 
TATAAGCTAG TGCCCAGAAA AGGAGTTAAG GCAAACGAGG TCCTCCAGAA CTTCCTGCAG 
TCACAGGTGG TTGTAGAGGA ATCCATCCTG CAGTCAGACA AAGCCCTCAC TGCTGGAGAG 
AAGGCCATAG CAGCGGAGCG GGCCATGAAG GAAGCAGCTG AGAAGGAACA GGAGCTGCTA 
AGAGAAAAAC AGAAGGAGCA GCAGCAAATG ATGGAGGCTC AAGAGAGAAG CTTCCAGGAA 
TACATGGCCC AAATGGAGAA GAAGTTGGAG GAGGAAAGGG AAAACCTTCT CAGAGAGCAT 
GAAAGGCTGC TAAAACACAA GCTGAAGGTA CAAGAAGAAA TGCTTAAGGA AGAATTTCAA 
AAGAAATCTG AGCAGTTAAA TAAAGAGATT AATCAACTGA AAGAAAAAAT TGAAAGCACT 
AAAAATGAAC AGTTAAGGCT CTTAAAGATC CTTGACATGG CTAGCAACAT AATGATTGTC 
ACTCTACCTG GGGCTTCCAA GCTACTTGGA GTAGGGACAA AATATCTTGG CTCACGTATT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_443173.2
CDS	117..2039
Translation	MGERTLHAAVPTPGYPESESIMMAPICLVENQEEQLTVNSKALEILDKISQPVVVVAIVGLYRTGKSYLMNRLAGKRNGFPLGSTVQSETKGIWMWCVPHLSKPNHTLVLLDTEGLGDVEKSNPKNDSWIFALAVLLSSSFVYNSVSTINHQALEQLHYVTELAELIRAKSCPRPDEAEDSSEFASFFPDFIWTVRDFTLELKLDGNPITEDEYLENALKLIPGKNPKIQNSNMPRECIRHFFRKRKCFVFDRPTNDKQYLNHMDEVPEENLERHFLMQSDNFCSYIFTHAKTKTLREGIIVTGKRLGTLVVTYVDAINSGAVPCLENAVTALAQLENPAAVQRAADHYSQQMAQQLRLPTDTLQELLDVHAACEREAIAVFMEHSFKDENHEFQKKLVDTIEKKKGDFVLQNEEASAKYCQAELKRLSEHLTESILRGIFSVPGGHNLYLEEKKQVEWDYKLVPRKGVKANEVLQNFLQSQVVVEESILQSDKALTAGEKAIAAERAMKEAAEKEQELLREKQKEQQQMMEAQERSFQEYMAQMEKKLEEERENLLREHERLLKHKLKVQEEMLKEEFQKKSEQLNKEINQLKEKIESTKNEQLRLLKILDMASNIMIVTLPGASKLLGVGTKYLGSRI

Target ORF information:

RefSeq Version	NM_052941.4
Organism	Homo sapiens(human)
Definition	Homo sapiens guanylate binding protein 4 (GBP4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_052941.4

ORF Insert Sequence:

ATGGGTGAGA GAACTCTTCA CGCTGCAGTG CCCACACCAG GTTATCCAGA ATCTGAATCC 
ATCATGATGG CCCCCATTTG TCTAGTGGAA AACCAGGAAG AGCAGCTGAC AGTGAATTCA 
AAGGCATTAG AGATTCTTGA CAAGATTTCT CAGCCCGTGG TGGTGGTGGC CATTGTAGGG 
CTATACCGCA CAGGAAAATC CTATCTCATG AATCGTCTTG CAGGAAAGCG CAATGGCTTC 
CCTCTGGGCT CCACGGTGCA GTCTGAAACT AAGGGCATCT GGATGTGGTG TGTGCCCCAC 
CTCTCTAAGC CAAACCACAC CCTGGTCCTT CTGGACACCG AGGGCCTGGG CGATGTAGAA 
AAGAGTAACC CTAAGAATGA CTCGTGGATC TTTGCCCTGG CTGTGCTTCT AAGCAGCAGC 
TTTGTCTATA ACAGCGTGAG CACCATCAAC CACCAGGCCC TGGAGCAGCT GCACTATGTG 
ACTGAGCTAG CAGAGCTAAT CAGGGCAAAA TCCTGCCCCA GACCTGATGA AGCTGAGGAC 
TCCAGCGAGT TTGCGAGTTT CTTTCCAGAC TTTATTTGGA CTGTTCGGGA TTTTACCCTG 
GAGCTAAAGT TAGATGGAAA CCCCATCACA GAAGATGAGT ACCTGGAGAA TGCCTTGAAG 
CTGATTCCAG GCAAGAATCC CAAAATTCAA AATTCAAACA TGCCTAGAGA GTGTATCAGG 
CATTTCTTCC GAAAACGGAA GTGCTTTGTC TTTGACCGGC CTACAAATGA CAAGCAATAT 
TTAAATCATA TGGACGAAGT GCCAGAAGAA AATCTGGAAA GGCATTTCCT TATGCAATCA 
GACAACTTCT GTTCTTATAT CTTCACCCAT GCAAAGACCA AGACCCTGAG AGAGGGAATC 
ATTGTCACTG GAAAGCGGCT GGGGACTCTG GTGGTGACTT ATGTAGATGC CATCAACAGT 
GGAGCAGTAC CTTGTCTGGA GAATGCAGTG ACAGCACTGG CCCAGCTTGA GAACCCAGCG 
GCTGTGCAGA GGGCAGCCGA CCACTATAGC CAGCAGATGG CCCAGCAACT GAGGCTCCCC 
ACAGACACGC TCCAGGAGCT GCTGGACGTG CATGCAGCCT GTGAGAGGGA AGCCATTGCA 
GTCTTCATGG AGCACTCCTT CAAGGATGAA AACCATGAAT TCCAGAAGAA GCTTGTGGAC 
ACCATAGAGA AAAAGAAGGG AGACTTTGTG CTGCAGAATG AAGAGGCATC TGCCAAATAT 
TGCCAGGCTG AGCTTAAGCG GCTTTCAGAG CACCTGACAG AAAGCATTTT GAGAGGAATT 
TTCTCTGTTC CTGGAGGACA CAATCTCTAC TTAGAAGAAA AGAAACAGGT TGAGTGGGAC 
TATAAGCTAG TGCCCAGAAA AGGAGTTAAG GCAAACGAGG TCCTCCAGAA CTTCCTGCAG 
TCACAGGTGG TTGTAGAGGA ATCCATCCTG CAGTCAGACA AAGCCCTCAC TGCTGGAGAG 
AAGGCCATAG CAGCGGAGCG GGCCATGAAG GAAGCAGCTG AGAAGGAACA GGAGCTGCTA 
AGAGAAAAAC AGAAGGAGCA GCAGCAAATG ATGGAGGCTC AAGAGAGAAG CTTCCAGGAA 
TACATGGCCC AAATGGAGAA GAAGTTGGAG GAGGAAAGGG AAAACCTTCT CAGAGAGCAT 
GAAAGGCTGC TAAAACACAA GCTGAAGGTA CAAGAAGAAA TGCTTAAGGA AGAATTTCAA 
AAGAAATCTG AGCAGTTAAA TAAAGAGATT AATCAACTGA AAGAAAAAAT TGAAAGCACT 
AAAAATGAAC AGTTAAGGCT CTTAAAGATC CTTGACATGG CTAGCAACAT AATGATTGTC 
ACTCTACCTG GGGCTTCCAA GCTACTTGGA GTAGGGACAA AATATCTTGG CTCACGTATT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GBP4 ( NM_052941.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_443173.2 Homo sapiens guanylate binding protein 4 (GBP4), mRNA.

Price & Availability↑

CloneID	OHu05592
Clone ID Related Accession (Same CDS sequence)	NM_052941.4 , NM_052941.5
Accession Version	NM_052941.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1923bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1568995200000
Organism	Homo sapiens(human)
Product	guanylate-binding protein 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC008421.1, AF288814.1, BC070055.1, AC104459.2 and CA309701.1. On Nov 22, 2018 this sequence version replaced NM_052941.4. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK312417.1, SRR1803613.167664.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000355754.7/ ENSP00000359490.5 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGTGAGA GAACTCTTCA CGCTGCAGTG CCCACACCAG GTTATCCAGA ATCTGAATCC 
ATCATGATGG CCCCCATTTG TCTAGTGGAA AACCAGGAAG AGCAGCTGAC AGTGAATTCA 
AAGGCATTAG AGATTCTTGA CAAGATTTCT CAGCCCGTGG TGGTGGTGGC CATTGTAGGG 
CTATACCGCA CAGGAAAATC CTATCTCATG AATCGTCTTG CAGGAAAGCG CAATGGCTTC 
CCTCTGGGCT CCACGGTGCA GTCTGAAACT AAGGGCATCT GGATGTGGTG TGTGCCCCAC 
CTCTCTAAGC CAAACCACAC CCTGGTCCTT CTGGACACCG AGGGCCTGGG CGATGTAGAA 
AAGAGTAACC CTAAGAATGA CTCGTGGATC TTTGCCCTGG CTGTGCTTCT AAGCAGCAGC 
TTTGTCTATA ACAGCGTGAG CACCATCAAC CACCAGGCCC TGGAGCAGCT GCACTATGTG 
ACTGAGCTAG CAGAGCTAAT CAGGGCAAAA TCCTGCCCCA GACCTGATGA AGCTGAGGAC 
TCCAGCGAGT TTGCGAGTTT CTTTCCAGAC TTTATTTGGA CTGTTCGGGA TTTTACCCTG 
GAGCTAAAGT TAGATGGAAA CCCCATCACA GAAGATGAGT ACCTGGAGAA TGCCTTGAAG 
CTGATTCCAG GCAAGAATCC CAAAATTCAA AATTCAAACA TGCCTAGAGA GTGTATCAGG 
CATTTCTTCC GAAAACGGAA GTGCTTTGTC TTTGACCGGC CTACAAATGA CAAGCAATAT 
TTAAATCATA TGGACGAAGT GCCAGAAGAA AATCTGGAAA GGCATTTCCT TATGCAATCA 
GACAACTTCT GTTCTTATAT CTTCACCCAT GCAAAGACCA AGACCCTGAG AGAGGGAATC 
ATTGTCACTG GAAAGCGGCT GGGGACTCTG GTGGTGACTT ATGTAGATGC CATCAACAGT 
GGAGCAGTAC CTTGTCTGGA GAATGCAGTG ACAGCACTGG CCCAGCTTGA GAACCCAGCG 
GCTGTGCAGA GGGCAGCCGA CCACTATAGC CAGCAGATGG CCCAGCAACT GAGGCTCCCC 
ACAGACACGC TCCAGGAGCT GCTGGACGTG CATGCAGCCT GTGAGAGGGA AGCCATTGCA 
GTCTTCATGG AGCACTCCTT CAAGGATGAA AACCATGAAT TCCAGAAGAA GCTTGTGGAC 
ACCATAGAGA AAAAGAAGGG AGACTTTGTG CTGCAGAATG AAGAGGCATC TGCCAAATAT 
TGCCAGGCTG AGCTTAAGCG GCTTTCAGAG CACCTGACAG AAAGCATTTT GAGAGGAATT 
TTCTCTGTTC CTGGAGGACA CAATCTCTAC TTAGAAGAAA AGAAACAGGT TGAGTGGGAC 
TATAAGCTAG TGCCCAGAAA AGGAGTTAAG GCAAACGAGG TCCTCCAGAA CTTCCTGCAG 
TCACAGGTGG TTGTAGAGGA ATCCATCCTG CAGTCAGACA AAGCCCTCAC TGCTGGAGAG 
AAGGCCATAG CAGCGGAGCG GGCCATGAAG GAAGCAGCTG AGAAGGAACA GGAGCTGCTA 
AGAGAAAAAC AGAAGGAGCA GCAGCAAATG ATGGAGGCTC AAGAGAGAAG CTTCCAGGAA 
TACATGGCCC AAATGGAGAA GAAGTTGGAG GAGGAAAGGG AAAACCTTCT CAGAGAGCAT 
GAAAGGCTGC TAAAACACAA GCTGAAGGTA CAAGAAGAAA TGCTTAAGGA AGAATTTCAA 
AAGAAATCTG AGCAGTTAAA TAAAGAGATT AATCAACTGA AAGAAAAAAT TGAAAGCACT 
AAAAATGAAC AGTTAAGGCT CTTAAAGATC CTTGACATGG CTAGCAACAT AATGATTGTC 
ACTCTACCTG GGGCTTCCAA GCTACTTGGA GTAGGGACAA AATATCTTGG CTCACGTATT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_443173.2
CDS	109..2031
Translation	MGERTLHAAVPTPGYPESESIMMAPICLVENQEEQLTVNSKALEILDKISQPVVVVAIVGLYRTGKSYLMNRLAGKRNGFPLGSTVQSETKGIWMWCVPHLSKPNHTLVLLDTEGLGDVEKSNPKNDSWIFALAVLLSSSFVYNSVSTINHQALEQLHYVTELAELIRAKSCPRPDEAEDSSEFASFFPDFIWTVRDFTLELKLDGNPITEDEYLENALKLIPGKNPKIQNSNMPRECIRHFFRKRKCFVFDRPTNDKQYLNHMDEVPEENLERHFLMQSDNFCSYIFTHAKTKTLREGIIVTGKRLGTLVVTYVDAINSGAVPCLENAVTALAQLENPAAVQRAADHYSQQMAQQLRLPTDTLQELLDVHAACEREAIAVFMEHSFKDENHEFQKKLVDTIEKKKGDFVLQNEEASAKYCQAELKRLSEHLTESILRGIFSVPGGHNLYLEEKKQVEWDYKLVPRKGVKANEVLQNFLQSQVVVEESILQSDKALTAGEKAIAAERAMKEAAEKEQELLREKQKEQQQMMEAQERSFQEYMAQMEKKLEEERENLLREHERLLKHKLKVQEEMLKEEFQKKSEQLNKEINQLKEKIESTKNEQLRLLKILDMASNIMIVTLPGASKLLGVGTKYLGSRI

Target ORF information:

RefSeq Version	NM_052941.5
Organism	Homo sapiens(human)
Definition	Homo sapiens guanylate binding protein 4 (GBP4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_052941.5

ORF Insert Sequence:

ATGGGTGAGA GAACTCTTCA CGCTGCAGTG CCCACACCAG GTTATCCAGA ATCTGAATCC 
ATCATGATGG CCCCCATTTG TCTAGTGGAA AACCAGGAAG AGCAGCTGAC AGTGAATTCA 
AAGGCATTAG AGATTCTTGA CAAGATTTCT CAGCCCGTGG TGGTGGTGGC CATTGTAGGG 
CTATACCGCA CAGGAAAATC CTATCTCATG AATCGTCTTG CAGGAAAGCG CAATGGCTTC 
CCTCTGGGCT CCACGGTGCA GTCTGAAACT AAGGGCATCT GGATGTGGTG TGTGCCCCAC 
CTCTCTAAGC CAAACCACAC CCTGGTCCTT CTGGACACCG AGGGCCTGGG CGATGTAGAA 
AAGAGTAACC CTAAGAATGA CTCGTGGATC TTTGCCCTGG CTGTGCTTCT AAGCAGCAGC 
TTTGTCTATA ACAGCGTGAG CACCATCAAC CACCAGGCCC TGGAGCAGCT GCACTATGTG 
ACTGAGCTAG CAGAGCTAAT CAGGGCAAAA TCCTGCCCCA GACCTGATGA AGCTGAGGAC 
TCCAGCGAGT TTGCGAGTTT CTTTCCAGAC TTTATTTGGA CTGTTCGGGA TTTTACCCTG 
GAGCTAAAGT TAGATGGAAA CCCCATCACA GAAGATGAGT ACCTGGAGAA TGCCTTGAAG 
CTGATTCCAG GCAAGAATCC CAAAATTCAA AATTCAAACA TGCCTAGAGA GTGTATCAGG 
CATTTCTTCC GAAAACGGAA GTGCTTTGTC TTTGACCGGC CTACAAATGA CAAGCAATAT 
TTAAATCATA TGGACGAAGT GCCAGAAGAA AATCTGGAAA GGCATTTCCT TATGCAATCA 
GACAACTTCT GTTCTTATAT CTTCACCCAT GCAAAGACCA AGACCCTGAG AGAGGGAATC 
ATTGTCACTG GAAAGCGGCT GGGGACTCTG GTGGTGACTT ATGTAGATGC CATCAACAGT 
GGAGCAGTAC CTTGTCTGGA GAATGCAGTG ACAGCACTGG CCCAGCTTGA GAACCCAGCG 
GCTGTGCAGA GGGCAGCCGA CCACTATAGC CAGCAGATGG CCCAGCAACT GAGGCTCCCC 
ACAGACACGC TCCAGGAGCT GCTGGACGTG CATGCAGCCT GTGAGAGGGA AGCCATTGCA 
GTCTTCATGG AGCACTCCTT CAAGGATGAA AACCATGAAT TCCAGAAGAA GCTTGTGGAC 
ACCATAGAGA AAAAGAAGGG AGACTTTGTG CTGCAGAATG AAGAGGCATC TGCCAAATAT 
TGCCAGGCTG AGCTTAAGCG GCTTTCAGAG CACCTGACAG AAAGCATTTT GAGAGGAATT 
TTCTCTGTTC CTGGAGGACA CAATCTCTAC TTAGAAGAAA AGAAACAGGT TGAGTGGGAC 
TATAAGCTAG TGCCCAGAAA AGGAGTTAAG GCAAACGAGG TCCTCCAGAA CTTCCTGCAG 
TCACAGGTGG TTGTAGAGGA ATCCATCCTG CAGTCAGACA AAGCCCTCAC TGCTGGAGAG 
AAGGCCATAG CAGCGGAGCG GGCCATGAAG GAAGCAGCTG AGAAGGAACA GGAGCTGCTA 
AGAGAAAAAC AGAAGGAGCA GCAGCAAATG ATGGAGGCTC AAGAGAGAAG CTTCCAGGAA 
TACATGGCCC AAATGGAGAA GAAGTTGGAG GAGGAAAGGG AAAACCTTCT CAGAGAGCAT 
GAAAGGCTGC TAAAACACAA GCTGAAGGTA CAAGAAGAAA TGCTTAAGGA AGAATTTCAA 
AAGAAATCTG AGCAGTTAAA TAAAGAGATT AATCAACTGA AAGAAAAAAT TGAAAGCACT 
AAAAATGAAC AGTTAAGGCT CTTAAAGATC CTTGACATGG CTAGCAACAT AATGATTGTC 
ACTCTACCTG GGGCTTCCAA GCTACTTGGA GTAGGGACAA AATATCTTGG CTCACGTATT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner.
PloS one5(12)e14246(2010 Dec)
Britzen-Laurent N,Bauer M,Berton V,Fischer N,Syguda A,Reipschläger S,Naschberger E,Herrmann C,Stürzl M

New genetic associations detected in a host response study to hepatitis B vaccine.
Genes and immunity11(3)232-8(2010 Apr)
Davila S,Froeling FE,Tan A,Bonnard C,Boland GJ,Snippe H,Hibberd ML,Seielstad M

Unique features of different members of the human guanylate-binding protein family.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research27(1)44-52(2007 Jan)
Tripal P,Bauer M,Naschberger E,Mörtinger T,Hohenadl C,Cornali E,Thurau M,Stürzl M

In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research26(5)328-52(2006 May)
Olszewski MA,Gray J,Vestal DJ

The guanylate-binding proteins (GBPs): proinflammatory cytokine-induced members of the dynamin superfamily with unique GTPase activity.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research25(8)435-43(2005 Aug)
Vestal DJ

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GBP4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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