| Gene Symbol | TMEM115 |
| Entrez Gene ID | 11070 |
| Full Name | transmembrane protein 115 |
| Synonyms | PL6 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Disorder MIM: |
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TMEM115 cDNA ORF clone, Homo sapiens(human)
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Gene
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Clones
gRNAs
The following TMEM115 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TMEM115 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OHu30830 
Clone ID Related Accession (Same CDS sequence) NM_007024.4 , NM_007024.5 Accession Version NM_007024.4 Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 1056bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1506700800000 Organism Homo sapiens(human) Product transmembrane protein 115 Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BF305563.1 and BC011948.1. On Jan 12, 2004 this sequence version replaced NM_007024.3. ##Evidence-Data-START## Transcript exon combination :: BC011948.1, SRR1660807.13279.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021ATGCAACGTG CCCTGCCAGG CGCCCGCCAG CACTTGGGGG CCATTCTGGC CAGCGCCAGC
GTGGTGGTGA AGGCTCTGTG TGCGGCGGTA CTATTCCTCT ACCTGCTCTC CTTCGCCGTG
GACACAGGCT GCCTGGCGGT CACCCCGGGC TACCTCTTTC CTCCCAACTT CTGGATCTGG
ACCCTGGCCA CCCATGGGCT GATGGAGCAG CATGTGTGGG ACGTGGCCAT CAGCCTGACA
ACGGTGGTGG TGGCCGGGCG TTTGCTGGAG CCCCTCTGGG GGGCCTTGGA GCTGCTCATC
TTCTTCTCAG TGGTGAATGT GTCTGTAGGG CTGCTGGGGG CCTTCGCCTA CCTCCTCACC
TACATGGCTT CCTTCAACCT GGTCTACCTG TTCACTGTCC GTATCCACGG CGCCTTGGGC
TTCCTAGGTG GCGTCCTGGT GGCACTCAAG CAAACCATGG GGGACTGTGT GGTCCTGCGA
GTGCCCCAGG TGCGCGTCAG TGTGATGCCC ATGCTGCTGC TGGCGCTGCT GCTCCTGCTG
CGGCTCGCCA CGCTGCTCCA GAGCCCGGCG CTGGCTTCCT ATGGCTTCGG GCTGCTCTCC
AGTTGGGTAT ATCTTCGCTT CTACCAGCGC CATAGCCGGG GCCGAGGGGA CATGGCTGAC
CACTTTGCTT TCGCCACTTT CTTCCCTGAG ATCCTGCAGC CTGTGGTGGG TTTGCTGGCG
AACTTGGTGC ACAGCCTCCT GGTGAAGGTA AAGATATGCC AGAAGACGGT GAAGCGCTAC
GATGTGGGTG CCCCATCCTC CATCACCATC AGCCTGCCAG GCACAGACCC TCAAGACGCC
GAGCGGAGAA GGCAACTGGC CCTGAAGGCA CTCAATGAGC GGCTGAAGAG AGTGGAAGAC
CAGTCCATCT GGCCCAGCAT GGATGATGAT GAAGAGGAGT CTGGGGCCAA GGTGGACAGC
CCCCTGCCCT CAGACAAAGC TCCCACACCC CCAGGGAAGG GGGCTGCCCC AGAATCCAGT
CTAATCACCT TCGAGGCAGC TCCCCCGACG CTGTAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_008955.1 CDS 446..1501 Translation 
Target ORF information:
RefSeq Version NM_007024.4 Organism Homo sapiens(human) Definition Homo sapiens transmembrane protein 115 (TMEM115), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_007024.4
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021ATGCAACGTG CCCTGCCAGG CGCCCGCCAG CACTTGGGGG CCATTCTGGC CAGCGCCAGC
GTGGTGGTGA AGGCTCTGTG TGCGGCGGTA CTATTCCTCT ACCTGCTCTC CTTCGCCGTG
GACACAGGCT GCCTGGCGGT CACCCCGGGC TACCTCTTTC CTCCCAACTT CTGGATCTGG
ACCCTGGCCA CCCATGGGCT GATGGAGCAG CATGTGTGGG ACGTGGCCAT CAGCCTGACA
ACGGTGGTGG TGGCCGGGCG TTTGCTGGAG CCCCTCTGGG GGGCCTTGGA GCTGCTCATC
TTCTTCTCAG TGGTGAATGT GTCTGTAGGG CTGCTGGGGG CCTTCGCCTA CCTCCTCACC
TACATGGCTT CCTTCAACCT GGTCTACCTG TTCACTGTCC GTATCCACGG CGCCTTGGGC
TTCCTAGGTG GCGTCCTGGT GGCACTCAAG CAAACCATGG GGGACTGTGT GGTCCTGCGA
GTGCCCCAGG TGCGCGTCAG TGTGATGCCC ATGCTGCTGC TGGCGCTGCT GCTCCTGCTG
CGGCTCGCCA CGCTGCTCCA GAGCCCGGCG CTGGCTTCCT ATGGCTTCGG GCTGCTCTCC
AGTTGGGTAT ATCTTCGCTT CTACCAGCGC CATAGCCGGG GCCGAGGGGA CATGGCTGAC
CACTTTGCTT TCGCCACTTT CTTCCCTGAG ATCCTGCAGC CTGTGGTGGG TTTGCTGGCG
AACTTGGTGC ACAGCCTCCT GGTGAAGGTA AAGATATGCC AGAAGACGGT GAAGCGCTAC
GATGTGGGTG CCCCATCCTC CATCACCATC AGCCTGCCAG GCACAGACCC TCAAGACGCC
GAGCGGAGAA GGCAACTGGC CCTGAAGGCA CTCAATGAGC GGCTGAAGAG AGTGGAAGAC
CAGTCCATCT GGCCCAGCAT GGATGATGAT GAAGAGGAGT CTGGGGCCAA GGTGGACAGC
CCCCTGCCCT CAGACAAAGC TCCCACACCC CCAGGGAAGG GGGCTGCCCC AGAATCCAGT
CTAATCACCT TCGAGGCAGC TCCCCCGACG CTGTAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID OHu30830 Clone ID Related Accession (Same CDS sequence) NM_007024.4 , NM_007024.5 Accession Version NM_007024.5 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 1056bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1569427200000 Organism Homo sapiens(human) Product transmembrane protein 115 Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from Z84492.2, BF305563.1 and BC011948.1. On Nov 24, 2018 this sequence version replaced NM_007024.4. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.547632.1, SRR1660807.13279.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000266025.4/ ENSP00000266025.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021ATGCAACGTG CCCTGCCAGG CGCCCGCCAG CACTTGGGGG CCATTCTGGC CAGCGCCAGC
GTGGTGGTGA AGGCTCTGTG TGCGGCGGTA CTATTCCTCT ACCTGCTCTC CTTCGCCGTG
GACACAGGCT GCCTGGCGGT CACCCCGGGC TACCTCTTTC CTCCCAACTT CTGGATCTGG
ACCCTGGCCA CCCATGGGCT GATGGAGCAG CATGTGTGGG ACGTGGCCAT CAGCCTGACA
ACGGTGGTGG TGGCCGGGCG TTTGCTGGAG CCCCTCTGGG GGGCCTTGGA GCTGCTCATC
TTCTTCTCAG TGGTGAATGT GTCTGTAGGG CTGCTGGGGG CCTTCGCCTA CCTCCTCACC
TACATGGCTT CCTTCAACCT GGTCTACCTG TTCACTGTCC GTATCCACGG CGCCTTGGGC
TTCCTAGGTG GCGTCCTGGT GGCACTCAAG CAAACCATGG GGGACTGTGT GGTCCTGCGA
GTGCCCCAGG TGCGCGTCAG TGTGATGCCC ATGCTGCTGC TGGCGCTGCT GCTCCTGCTG
CGGCTCGCCA CGCTGCTCCA GAGCCCGGCG CTGGCTTCCT ATGGCTTCGG GCTGCTCTCC
AGTTGGGTAT ATCTTCGCTT CTACCAGCGC CATAGCCGGG GCCGAGGGGA CATGGCTGAC
CACTTTGCTT TCGCCACTTT CTTCCCTGAG ATCCTGCAGC CTGTGGTGGG TTTGCTGGCG
AACTTGGTGC ACAGCCTCCT GGTGAAGGTA AAGATATGCC AGAAGACGGT GAAGCGCTAC
GATGTGGGTG CCCCATCCTC CATCACCATC AGCCTGCCAG GCACAGACCC TCAAGACGCC
GAGCGGAGAA GGCAACTGGC CCTGAAGGCA CTCAATGAGC GGCTGAAGAG AGTGGAAGAC
CAGTCCATCT GGCCCAGCAT GGATGATGAT GAAGAGGAGT CTGGGGCCAA GGTGGACAGC
CCCCTGCCCT CAGACAAAGC TCCCACACCC CCAGGGAAGG GGGCTGCCCC AGAATCCAGT
CTAATCACCT TCGAGGCAGC TCCCCCGACG CTGTAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_008955.1 CDS 459..1514 Translation
Target ORF information:
RefSeq Version NM_007024.5 Organism Homo sapiens(human) Definition Homo sapiens transmembrane protein 115 (TMEM115), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK NM_007024.5
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021ATGCAACGTG CCCTGCCAGG CGCCCGCCAG CACTTGGGGG CCATTCTGGC CAGCGCCAGC
GTGGTGGTGA AGGCTCTGTG TGCGGCGGTA CTATTCCTCT ACCTGCTCTC CTTCGCCGTG
GACACAGGCT GCCTGGCGGT CACCCCGGGC TACCTCTTTC CTCCCAACTT CTGGATCTGG
ACCCTGGCCA CCCATGGGCT GATGGAGCAG CATGTGTGGG ACGTGGCCAT CAGCCTGACA
ACGGTGGTGG TGGCCGGGCG TTTGCTGGAG CCCCTCTGGG GGGCCTTGGA GCTGCTCATC
TTCTTCTCAG TGGTGAATGT GTCTGTAGGG CTGCTGGGGG CCTTCGCCTA CCTCCTCACC
TACATGGCTT CCTTCAACCT GGTCTACCTG TTCACTGTCC GTATCCACGG CGCCTTGGGC
TTCCTAGGTG GCGTCCTGGT GGCACTCAAG CAAACCATGG GGGACTGTGT GGTCCTGCGA
GTGCCCCAGG TGCGCGTCAG TGTGATGCCC ATGCTGCTGC TGGCGCTGCT GCTCCTGCTG
CGGCTCGCCA CGCTGCTCCA GAGCCCGGCG CTGGCTTCCT ATGGCTTCGG GCTGCTCTCC
AGTTGGGTAT ATCTTCGCTT CTACCAGCGC CATAGCCGGG GCCGAGGGGA CATGGCTGAC
CACTTTGCTT TCGCCACTTT CTTCCCTGAG ATCCTGCAGC CTGTGGTGGG TTTGCTGGCG
AACTTGGTGC ACAGCCTCCT GGTGAAGGTA AAGATATGCC AGAAGACGGT GAAGCGCTAC
GATGTGGGTG CCCCATCCTC CATCACCATC AGCCTGCCAG GCACAGACCC TCAAGACGCC
GAGCGGAGAA GGCAACTGGC CCTGAAGGCA CTCAATGAGC GGCTGAAGAG AGTGGAAGAC
CAGTCCATCT GGCCCAGCAT GGATGATGAT GAAGAGGAGT CTGGGGCCAA GGTGGACAGC
CCCCTGCCCT CAGACAAAGC TCCCACACCC CCAGGGAAGG GGGCTGCCCC AGAATCCAGT
CTAATCACCT TCGAGGCAGC TCCCCCGACG CTGTAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
TMEM115 is an integral membrane protein of the Golgi complex involved in retrograde transport.
Journal of cell science127(Pt 13)2825-39(2014 Jul)
Ong YS,Tran TH,Gounko NV,Hong W
Loss of PL6 protein expression in renal clear cell carcinomas and other VHL-deficient tumours.
The Journal of pathology214(1)46-57(2008 Jan)
Ivanova AV,Vortmeyer A,Ivanov SV,Nickerson ML,Maher ER,Lerman MI
The DNA sequence, annotation and analysis of human chromosome 3.
Nature440(7088)1194-8(2006 Apr)
Muzny DM,Scherer SE,Kaul R,Wang J,Yu J,Sudbrak R,Buhay CJ,Chen R,Cree A,Ding Y,Dugan-Rocha S,Gill R,Gunaratne P,Harris RA,Hawes AC,Hernandez J,Hodgson AV,Hume J,Jackson A,Khan ZM,Kovar-Smith C,Lewis LR,Lozado RJ,Metzker ML,Milosavljevic A,Miner GR,Morgan MB,Nazareth LV,Scott G,Sodergren E,Song XZ,Steffen D,Wei S,Wheeler DA,Wright MW,Worley KC,Yuan Y,Zhang Z,Adams CQ,Ansari-Lari MA,Ayele M,Brown MJ,Chen G,Chen Z,Clendenning J,Clerc-Blankenburg KP,Chen R,Chen Z,Davis C,Delgado O,Dinh HH,Dong W,Draper H,Ernst S,Fu G,Gonzalez-Garay ML,Garcia DK,Gillett W,Gu J,Hao B,Haugen E,Havlak P,He X,Hennig S,Hu S,Huang W,Jackson LR,Jacob LS,Kelly SH,Kube M,Levy R,Li Z,Liu B,Liu J,Liu W,Lu J,Maheshwari M,Nguyen BV,Okwuonu GO,Palmeiri A,Pasternak S,Perez LM,Phelps KA,Plopper FJ,Qiang B,Raymond C,Rodriguez R,Saenphimmachak C,Santibanez J,Shen H,Shen Y,Subramanian S,Tabor PE,Verduzco D,Waldron L,Wang J,Wang J,Wang Q,Williams GA,Wong GK,Yao Z,Zhang J,Zhang X,Zhao G,Zhou J,Zhou Y,Nelson D,Lehrach H,Reinhardt R,Naylor SL,Yang H,Olson M,Weinstock G,Gibbs RA
A family of cAMP-binding proteins that directly activate Rap1.
Science (New York, N.Y.)282(5397)2275-9(1998 Dec)
Kawasaki H,Springett GM,Mochizuki N,Toki S,Nakaya M,Matsuda M,Housman DE,Graybiel AM
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