YKT6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	YKT6
Entrez Gene ID	10652
Full Name	YKT6 v-SNARE homolog
General protein information	Preferred Names YKT6 v-SNARE homolog Names synaptobrevin homolog YKT6 R-SNARE SNARE protein Ykt6 YKT6 v-SNARE protein YKT6, S. cerevisiae, homolog of
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7p13
Summary	This gene product is one of the SNARE recognition molecules implicated in vesicular transport between secretory compartments. It is a membrane associated, isoprenylated protein that functions at the endoplasmic reticulum-Golgi transport step. This protein is highly conserved from yeast to human and can functionally complement the loss of the yeast homolog in the yeast secretory pathway. [provided by RefSeq, Jul 2008].
Disorder MIM:	606209

mRNA and Protein(s)

mRNA	Protein	Name
XM_005249582.4	XP_005249639.1	synaptobrevin homolog YKT6 isoform X1
NM_001363678.1	NP_001350607.1	synaptobrevin homolog YKT6 isoform 2
NM_006555.4	NP_006546.1	synaptobrevin homolog YKT6 isoform 1
XM_017011682.1	XP_016867171.1	synaptobrevin homolog YKT6 isoform X2
NM_001363678.2	NP_001350607.1	synaptobrevin homolog YKT6 isoform 2
NM_006555.3	NP_006546.1	synaptobrevin homolog YKT6

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	Ykt6	NP_572423.1
Oryza sativa (rice)	Os01g0866300	NP_001044905.1
Schizosaccharomyces pombe (fission yeast)	ykt6	NP_596561.1
Canis lupus familiaris (dog)	YKT6	XP_532720.2
Xenopus tropicalis (tropical clawed frog)	ykt6	NP_989023.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000392	XP_310711.2
Eremothecium gossypii	AGOS_AER109W	NP_984969.1
Mus musculus (house mouse)	Ykt6	NP_062635.2
Danio rerio (zebrafish)	ykt6	NP_957386.1
Saccharomyces cerevisiae (baker's yeast)	YKT6	NP_012725.1
Homo sapiens (human)	YKT6	NP_006546.1
Macaca mulatta (Rhesus monkey)	YKT6	XP_001092567.1
Rattus norvegicus (Norway rat)	Ykt6	NP_113880.2
Caenorhabditis elegans (roundworm)	ykt-6	NP_498605.1
Magnaporthe oryzae (rice blast fungus)	MGG_06125	XP_003711992.1
Kluyveromyces lactis	KLLA0D02684g	XP_453187.1
Pan troglodytes (chimpanzee)	YKT6	XP_001144106.1
Bos taurus (cattle)	YKT6	NP_001030219.1
Gallus gallus (chicken)	YKT6	NP_001107216.1
Neurospora crassa	NCU08973	XP_959001.2

Gene Ontology
Bibliography

Related articles in PubMed

Autophagosomal YKT6 is required for fusion with lysosomes independently of syntaxin 17.
Matsui T, Jiang P, Nakano S, Sakamaki Y, Yamamoto H, Mizushima N
The Journal of cell biology217(8)2633-2645(2018 08)

A membrane fusion protein, Ykt6, regulates epithelial cell migration via microRNA-mediated suppression of Junctional Adhesion Molecule A.
Naydenov NG, Joshi S, Feygin A, Saini S, Litovchick L, Ivanov AI
Cell cycle (Georgetown, Tex.)17(14)1812-1831(2018)

YKT6 expression, exosome release, and survival in non-small cell lung cancer.
Ruiz-Martinez M, Navarro A, Marrades RM, Viñolas N, Santasusagna S, Muñoz C, Ramírez J, Molins L, Monzo M
Oncotarget7(32)51515-51524(2016 Aug)

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Guo Z, Neilson LJ, Zhong H, Murray PS, Zanivan S, Zaidel-Bar R
Science signaling7(354)rs7(2014 Dec)

Possible involvement of CCT5, RGS3, and YKT6 genes up-regulated in p53-mutated tumors in resistance to docetaxel in human breast cancers.
Ooe A, Kato K, Noguchi S
Breast cancer research and treatment101(3)305-15(2007 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following YKT6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the YKT6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu97010	NM_001363678.2 Latest version!	Homo sapiens YKT6 v-SNARE homolog (YKT6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu41061	XM_005249582.4 Latest version!	Homo sapiens YKT6 v-SNARE homolog (YKT6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu97010	XM_017011682.1 Latest version!	Homo sapiens YKT6 v-SNARE homolog (S. cerevisiae) (YKT6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu30137	NM_006555.4 Latest version!	Homo sapiens YKT6 v-SNARE homolog (YKT6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$104.30 $149.00
View Old Accession Versions >>
OHu97010	NM_001363678.1	Homo sapiens YKT6 v-SNARE homolog (YKT6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu30137	NM_006555.3	Homo sapiens YKT6 v-SNARE homolog (YKT6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$104.30 $149.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

YKT6 ( NM_001363678.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001350607.1 Homo sapiens YKT6 v-SNARE homolog (YKT6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu97010
Clone ID Related Accession (Same CDS sequence)	NM_001363678.1 , XM_017011682.1 , NM_001363678.2
Accession Version	NM_001363678.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 495bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1530288000000
Organism	Homo sapiens(human)
Product	synaptobrevin homolog YKT6 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK299158.1 and BC007319.2. On May 30, 2018 this sequence version replaced XM_017011682.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.155702.1, AK299158.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END##

ATGAAGCTGT ACAGCCTCAG CGTCCTCTAC AAAGGCGAGG CCAAGGTGGT GCTGCTCAAA 
GCCGCATACG ATGTGTCTTC CTTCAGCTTT TTCCAGAGAT CCAGCGTTCA GGAATTCATG 
ACCTTCACGA GTCAACTGAT TGTGGAGCGC TCATCGAAAG GCACTAGAGC TTCTGTCAAA 
GAACAAGACT ATCTGTGCCA CGTCTACGTC CGGAATGATA GTCTTGCAGG TGTGGTCATT 
GCTGACAATG AATACCCATC CCGGGTGGCC TTTACCTTGC TGGAGAAGGT ACTAGATGAA 
TTCTCCAAGC AAGTCGACAG GATAGACTGG CCAGTAGGAT CCCCTGCTAC AATCCATTAC 
CCAGCCCTGG ATGGTCACCT CAGTAGATAC CAGAACCCAC GAGAAGCTGA TCCCATGACT 
AAAGTGCAGG CCGAACTAGA TGAGACCAAA ATCATTCTGG CCCGGAAACA AAACTCATGC 
TGTGCCATCA TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001350607.1
CDS	157..651
Translation	MKLYSLSVLYKGEAKVVLLKAAYDVSSFSFFQRSSVQEFMTFTSQLIVERSSKGTRASVKEQDYLCHVYVRNDSLAGVVIADNEYPSRVAFTLLEKVLDEFSKQVDRIDWPVGSPATIHYPALDGHLSRYQNPREADPMTKVQAELDETKIILARKQNSCCAIM

Target ORF information:

RefSeq Version	NM_001363678.1
Organism	Homo sapiens(human)
Definition	Homo sapiens YKT6 v-SNARE homolog (YKT6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001363678.1

ORF Insert Sequence:

ATGAAGCTGT ACAGCCTCAG CGTCCTCTAC AAAGGCGAGG CCAAGGTGGT GCTGCTCAAA 
GCCGCATACG ATGTGTCTTC CTTCAGCTTT TTCCAGAGAT CCAGCGTTCA GGAATTCATG 
ACCTTCACGA GTCAACTGAT TGTGGAGCGC TCATCGAAAG GCACTAGAGC TTCTGTCAAA 
GAACAAGACT ATCTGTGCCA CGTCTACGTC CGGAATGATA GTCTTGCAGG TGTGGTCATT 
GCTGACAATG AATACCCATC CCGGGTGGCC TTTACCTTGC TGGAGAAGGT ACTAGATGAA 
TTCTCCAAGC AAGTCGACAG GATAGACTGG CCAGTAGGAT CCCCTGCTAC AATCCATTAC 
CCAGCCCTGG ATGGTCACCT CAGTAGATAC CAGAACCCAC GAGAAGCTGA TCCCATGACT 
AAAGTGCAGG CCGAACTAGA TGAGACCAAA ATCATTCTGG CCCGGAAACA AAACTCATGC 
TGTGCCATCA TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

YKT6 ( NM_001363678.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001350607.1 Homo sapiens YKT6 v-SNARE homolog (YKT6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu97010
Clone ID Related Accession (Same CDS sequence)	NM_001363678.1 , XM_017011682.1 , NM_001363678.2
Accession Version	NM_001363678.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 495bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573315200000
Organism	Homo sapiens(human)
Product	synaptobrevin homolog YKT6 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC006454.4, AK299158.1 and BC007319.2. On May 31, 2019 this sequence version replaced NM_001363678.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.155702.1, AK299158.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END##

ATGAAGCTGT ACAGCCTCAG CGTCCTCTAC AAAGGCGAGG CCAAGGTGGT GCTGCTCAAA 
GCCGCATACG ATGTGTCTTC CTTCAGCTTT TTCCAGAGAT CCAGCGTTCA GGAATTCATG 
ACCTTCACGA GTCAACTGAT TGTGGAGCGC TCATCGAAAG GCACTAGAGC TTCTGTCAAA 
GAACAAGACT ATCTGTGCCA CGTCTACGTC CGGAATGATA GTCTTGCAGG TGTGGTCATT 
GCTGACAATG AATACCCATC CCGGGTGGCC TTTACCTTGC TGGAGAAGGT ACTAGATGAA 
TTCTCCAAGC AAGTCGACAG GATAGACTGG CCAGTAGGAT CCCCTGCTAC AATCCATTAC 
CCAGCCCTGG ATGGTCACCT CAGTAGATAC CAGAACCCAC GAGAAGCTGA TCCCATGACT 
AAAGTGCAGG CCGAACTAGA TGAGACCAAA ATCATTCTGG CCCGGAAACA AAACTCATGC 
TGTGCCATCA TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001350607.1
CDS	159..653
Translation	MKLYSLSVLYKGEAKVVLLKAAYDVSSFSFFQRSSVQEFMTFTSQLIVERSSKGTRASVKEQDYLCHVYVRNDSLAGVVIADNEYPSRVAFTLLEKVLDEFSKQVDRIDWPVGSPATIHYPALDGHLSRYQNPREADPMTKVQAELDETKIILARKQNSCCAIM

Target ORF information:

RefSeq Version	NM_001363678.2
Organism	Homo sapiens(human)
Definition	Homo sapiens YKT6 v-SNARE homolog (YKT6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001363678.2

ORF Insert Sequence:

ATGAAGCTGT ACAGCCTCAG CGTCCTCTAC AAAGGCGAGG CCAAGGTGGT GCTGCTCAAA 
GCCGCATACG ATGTGTCTTC CTTCAGCTTT TTCCAGAGAT CCAGCGTTCA GGAATTCATG 
ACCTTCACGA GTCAACTGAT TGTGGAGCGC TCATCGAAAG GCACTAGAGC TTCTGTCAAA 
GAACAAGACT ATCTGTGCCA CGTCTACGTC CGGAATGATA GTCTTGCAGG TGTGGTCATT 
GCTGACAATG AATACCCATC CCGGGTGGCC TTTACCTTGC TGGAGAAGGT ACTAGATGAA 
TTCTCCAAGC AAGTCGACAG GATAGACTGG CCAGTAGGAT CCCCTGCTAC AATCCATTAC 
CCAGCCCTGG ATGGTCACCT CAGTAGATAC CAGAACCCAC GAGAAGCTGA TCCCATGACT 
AAAGTGCAGG CCGAACTAGA TGAGACCAAA ATCATTCTGG CCCGGAAACA AAACTCATGC 
TGTGCCATCA TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

YKT6 ( XM_005249582.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005249639.1 Homo sapiens YKT6 v-SNARE homolog (YKT6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu41061
Clone ID Related Accession (Same CDS sequence)	XM_005249582.4
Accession Version	XM_005249582.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 576bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	synaptobrevin homolog YKT6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005249582.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGCTGT ACAGCCTCAG CGTCCTCTAC AAAGGCGAGG CCAAGGTGGT GCTGCTCAAA 
GCCGCATACG ATGTGTCTTC CTTCAGCTTT TTCCAGAGAT CCAGCGTTCA GGAATTCATG 
ACCTTCACGA GTCAACTGAT TGTGGAGCGC TCATCGAAAG GCACTAGAGC TTCTGTCAAA 
GAACAAGACT ATCTGTGCCA CGTCTACGTC CGGAATGATA GTCTTGCAGG TGTGGTCATT 
GCTGACAATG AATACCCATC CCGGGTGGCC TTTACCTTGC TGGAGAAGGT ACTAGATGAA 
TTCTCCAAGC AAGTCGACAG GATAGACTGG CCAGTAGGAT CCCCTGCTAC AATCCATTAC 
CCAGCCCTGG ATGGTCACCT CAGTAGATAC CAGAACCCAC GAGAAGCTGA TCCCATGACT 
AAAGTGCAGG CCGAACTAGA TGAGACCAAA ATCATTCTGC ACAACACCAT GGAGTCTCTG 
TTAGAGCGAG GTGAGAAGCT AGATGACTTG GTGTCCAAAT CCGAGGTGCT GGGAACACAG 
TCTAAAGCCT TCTATAAAAC TAAAATATTT AATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005249639.1
CDS	159..734
Translation	MKLYSLSVLYKGEAKVVLLKAAYDVSSFSFFQRSSVQEFMTFTSQLIVERSSKGTRASVKEQDYLCHVYVRNDSLAGVVIADNEYPSRVAFTLLEKVLDEFSKQVDRIDWPVGSPATIHYPALDGHLSRYQNPREADPMTKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTKIFN

Target ORF information:

RefSeq Version	XM_005249582.4
Organism	Homo sapiens(human)
Definition	Homo sapiens YKT6 v-SNARE homolog (YKT6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005249582.4

ORF Insert Sequence:

ATGAAGCTGT ACAGCCTCAG CGTCCTCTAC AAAGGCGAGG CCAAGGTGGT GCTGCTCAAA 
GCCGCATACG ATGTGTCTTC CTTCAGCTTT TTCCAGAGAT CCAGCGTTCA GGAATTCATG 
ACCTTCACGA GTCAACTGAT TGTGGAGCGC TCATCGAAAG GCACTAGAGC TTCTGTCAAA 
GAACAAGACT ATCTGTGCCA CGTCTACGTC CGGAATGATA GTCTTGCAGG TGTGGTCATT 
GCTGACAATG AATACCCATC CCGGGTGGCC TTTACCTTGC TGGAGAAGGT ACTAGATGAA 
TTCTCCAAGC AAGTCGACAG GATAGACTGG CCAGTAGGAT CCCCTGCTAC AATCCATTAC 
CCAGCCCTGG ATGGTCACCT CAGTAGATAC CAGAACCCAC GAGAAGCTGA TCCCATGACT 
AAAGTGCAGG CCGAACTAGA TGAGACCAAA ATCATTCTGC ACAACACCAT GGAGTCTCTG 
TTAGAGCGAG GTGAGAAGCT AGATGACTTG GTGTCCAAAT CCGAGGTGCT GGGAACACAG 
TCTAAAGCCT TCTATAAAAC TAAAATATTT AATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

YKT6 ( XM_017011682.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016867171.1 Homo sapiens YKT6 v-SNARE homolog (S. cerevisiae) (YKT6), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu97010
Clone ID Related Accession (Same CDS sequence)	NM_001363678.1 , XM_017011682.1 , NM_001363678.2
Accession Version	XM_017011682.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 495bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	synaptobrevin homolog YKT6 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGCTGT ACAGCCTCAG CGTCCTCTAC AAAGGCGAGG CCAAGGTGGT GCTGCTCAAA 
GCCGCATACG ATGTGTCTTC CTTCAGCTTT TTCCAGAGAT CCAGCGTTCA GGAATTCATG 
ACCTTCACGA GTCAACTGAT TGTGGAGCGC TCATCGAAAG GCACTAGAGC TTCTGTCAAA 
GAACAAGACT ATCTGTGCCA CGTCTACGTC CGGAATGATA GTCTTGCAGG TGTGGTCATT 
GCTGACAATG AATACCCATC CCGGGTGGCC TTTACCTTGC TGGAGAAGGT ACTAGATGAA 
TTCTCCAAGC AAGTCGACAG GATAGACTGG CCAGTAGGAT CCCCTGCTAC AATCCATTAC 
CCAGCCCTGG ATGGTCACCT CAGTAGATAC CAGAACCCAC GAGAAGCTGA TCCCATGACT 
AAAGTGCAGG CCGAACTAGA TGAGACCAAA ATCATTCTGG CCCGGAAACA AAACTCATGC 
TGTGCCATCA TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016867171.1
CDS	169..663
Translation	MKLYSLSVLYKGEAKVVLLKAAYDVSSFSFFQRSSVQEFMTFTSQLIVERSSKGTRASVKEQDYLCHVYVRNDSLAGVVIADNEYPSRVAFTLLEKVLDEFSKQVDRIDWPVGSPATIHYPALDGHLSRYQNPREADPMTKVQAELDETKIILARKQNSCCAIM

Target ORF information:

RefSeq Version	XM_017011682.1
Organism	Homo sapiens(human)
Definition	Homo sapiens YKT6 v-SNARE homolog (S. cerevisiae) (YKT6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017011682.1

ORF Insert Sequence:

ATGAAGCTGT ACAGCCTCAG CGTCCTCTAC AAAGGCGAGG CCAAGGTGGT GCTGCTCAAA 
GCCGCATACG ATGTGTCTTC CTTCAGCTTT TTCCAGAGAT CCAGCGTTCA GGAATTCATG 
ACCTTCACGA GTCAACTGAT TGTGGAGCGC TCATCGAAAG GCACTAGAGC TTCTGTCAAA 
GAACAAGACT ATCTGTGCCA CGTCTACGTC CGGAATGATA GTCTTGCAGG TGTGGTCATT 
GCTGACAATG AATACCCATC CCGGGTGGCC TTTACCTTGC TGGAGAAGGT ACTAGATGAA 
TTCTCCAAGC AAGTCGACAG GATAGACTGG CCAGTAGGAT CCCCTGCTAC AATCCATTAC 
CCAGCCCTGG ATGGTCACCT CAGTAGATAC CAGAACCCAC GAGAAGCTGA TCCCATGACT 
AAAGTGCAGG CCGAACTAGA TGAGACCAAA ATCATTCTGG CCCGGAAACA AAACTCATGC 
TGTGCCATCA TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

YKT6 ( NM_006555.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006546.1 Homo sapiens YKT6 v-SNARE homolog (YKT6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu30137
Clone ID Related Accession (Same CDS sequence)	NM_006555.4 , NM_006555.3
Accession Version	NM_006555.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 597bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573315200000
Organism	Homo sapiens(human)
Product	synaptobrevin homolog YKT6 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC006454.4, AU130339.1 and BC007319.2. On Nov 23, 2018 this sequence version replaced NM_006555.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.938251.1, SRR3476690.962189.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000223369.3/ ENSP00000223369.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGCTGT ACAGCCTCAG CGTCCTCTAC AAAGGCGAGG CCAAGGTGGT GCTGCTCAAA 
GCCGCATACG ATGTGTCTTC CTTCAGCTTT TTCCAGAGAT CCAGCGTTCA GGAATTCATG 
ACCTTCACGA GTCAACTGAT TGTGGAGCGC TCATCGAAAG GCACTAGAGC TTCTGTCAAA 
GAACAAGACT ATCTGTGCCA CGTCTACGTC CGGAATGATA GTCTTGCAGG TGTGGTCATT 
GCTGACAATG AATACCCATC CCGGGTGGCC TTTACCTTGC TGGAGAAGGT ACTAGATGAA 
TTCTCCAAGC AAGTCGACAG GATAGACTGG CCAGTAGGAT CCCCTGCTAC AATCCATTAC 
CCAGCCCTGG ATGGTCACCT CAGTAGATAC CAGAACCCAC GAGAAGCTGA TCCCATGACT 
AAAGTGCAGG CCGAACTAGA TGAGACCAAA ATCATTCTGC ACAACACCAT GGAGTCTCTG 
TTAGAGCGAG GTGAGAAGCT AGATGACTTG GTGTCCAAAT CCGAGGTGCT GGGAACACAG 
TCTAAAGCCT TCTATAAAAC TGCCCGGAAA CAAAACTCAT GCTGTGCCAT CATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006546.1
CDS	159..755
Translation	MKLYSLSVLYKGEAKVVLLKAAYDVSSFSFFQRSSVQEFMTFTSQLIVERSSKGTRASVKEQDYLCHVYVRNDSLAGVVIADNEYPSRVAFTLLEKVLDEFSKQVDRIDWPVGSPATIHYPALDGHLSRYQNPREADPMTKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTARKQNSCCAIM

Target ORF information:

RefSeq Version	NM_006555.4
Organism	Homo sapiens(human)
Definition	Homo sapiens YKT6 v-SNARE homolog (YKT6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006555.4

ORF Insert Sequence:

ATGAAGCTGT ACAGCCTCAG CGTCCTCTAC AAAGGCGAGG CCAAGGTGGT GCTGCTCAAA 
GCCGCATACG ATGTGTCTTC CTTCAGCTTT TTCCAGAGAT CCAGCGTTCA GGAATTCATG 
ACCTTCACGA GTCAACTGAT TGTGGAGCGC TCATCGAAAG GCACTAGAGC TTCTGTCAAA 
GAACAAGACT ATCTGTGCCA CGTCTACGTC CGGAATGATA GTCTTGCAGG TGTGGTCATT 
GCTGACAATG AATACCCATC CCGGGTGGCC TTTACCTTGC TGGAGAAGGT ACTAGATGAA 
TTCTCCAAGC AAGTCGACAG GATAGACTGG CCAGTAGGAT CCCCTGCTAC AATCCATTAC 
CCAGCCCTGG ATGGTCACCT CAGTAGATAC CAGAACCCAC GAGAAGCTGA TCCCATGACT 
AAAGTGCAGG CCGAACTAGA TGAGACCAAA ATCATTCTGC ACAACACCAT GGAGTCTCTG 
TTAGAGCGAG GTGAGAAGCT AGATGACTTG GTGTCCAAAT CCGAGGTGCT GGGAACACAG 
TCTAAAGCCT TCTATAAAAC TGCCCGGAAA CAAAACTCAT GCTGTGCCAT CATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

YKT6 ( NM_006555.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006546.1 Homo sapiens YKT6 v-SNARE homolog (YKT6), mRNA.

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CloneID	OHu30137
Clone ID Related Accession (Same CDS sequence)	NM_006555.4 , NM_006555.3
Accession Version	NM_006555.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 597bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506700800000
Organism	Homo sapiens(human)
Product	synaptobrevin homolog YKT6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AU130339.1 and BC007319.2. On Aug 27, 2003 this sequence version replaced NM_006555.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.56628.1, SRR1803615.250835.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGCTGT ACAGCCTCAG CGTCCTCTAC AAAGGCGAGG CCAAGGTGGT GCTGCTCAAA 
GCCGCATACG ATGTGTCTTC CTTCAGCTTT TTCCAGAGAT CCAGCGTTCA GGAATTCATG 
ACCTTCACGA GTCAACTGAT TGTGGAGCGC TCATCGAAAG GCACTAGAGC TTCTGTCAAA 
GAACAAGACT ATCTGTGCCA CGTCTACGTC CGGAATGATA GTCTTGCAGG TGTGGTCATT 
GCTGACAATG AATACCCATC CCGGGTGGCC TTTACCTTGC TGGAGAAGGT ACTAGATGAA 
TTCTCCAAGC AAGTCGACAG GATAGACTGG CCAGTAGGAT CCCCTGCTAC AATCCATTAC 
CCAGCCCTGG ATGGTCACCT CAGTAGATAC CAGAACCCAC GAGAAGCTGA TCCCATGACT 
AAAGTGCAGG CCGAACTAGA TGAGACCAAA ATCATTCTGC ACAACACCAT GGAGTCTCTG 
TTAGAGCGAG GTGAGAAGCT AGATGACTTG GTGTCCAAAT CCGAGGTGCT GGGAACACAG 
TCTAAAGCCT TCTATAAAAC TGCCCGGAAA CAAAACTCAT GCTGTGCCAT CATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006546.1
CDS	158..754
Translation	MKLYSLSVLYKGEAKVVLLKAAYDVSSFSFFQRSSVQEFMTFTSQLIVERSSKGTRASVKEQDYLCHVYVRNDSLAGVVIADNEYPSRVAFTLLEKVLDEFSKQVDRIDWPVGSPATIHYPALDGHLSRYQNPREADPMTKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTARKQNSCCAIM

Target ORF information:

RefSeq Version	NM_006555.3
Organism	Homo sapiens(human)
Definition	Homo sapiens YKT6 v-SNARE homolog (YKT6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006555.3

ORF Insert Sequence:

ATGAAGCTGT ACAGCCTCAG CGTCCTCTAC AAAGGCGAGG CCAAGGTGGT GCTGCTCAAA 
GCCGCATACG ATGTGTCTTC CTTCAGCTTT TTCCAGAGAT CCAGCGTTCA GGAATTCATG 
ACCTTCACGA GTCAACTGAT TGTGGAGCGC TCATCGAAAG GCACTAGAGC TTCTGTCAAA 
GAACAAGACT ATCTGTGCCA CGTCTACGTC CGGAATGATA GTCTTGCAGG TGTGGTCATT 
GCTGACAATG AATACCCATC CCGGGTGGCC TTTACCTTGC TGGAGAAGGT ACTAGATGAA 
TTCTCCAAGC AAGTCGACAG GATAGACTGG CCAGTAGGAT CCCCTGCTAC AATCCATTAC 
CCAGCCCTGG ATGGTCACCT CAGTAGATAC CAGAACCCAC GAGAAGCTGA TCCCATGACT 
AAAGTGCAGG CCGAACTAGA TGAGACCAAA ATCATTCTGC ACAACACCAT GGAGTCTCTG 
TTAGAGCGAG GTGAGAAGCT AGATGACTTG GTGTCCAAAT CCGAGGTGCT GGGAACACAG 
TCTAAAGCCT TCTATAAAAC TGCCCGGAAA CAAAACTCAT GCTGTGCCAT CATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Autophagosomal YKT6 is required for fusion with lysosomes independently of syntaxin 17.
The Journal of cell biology217(8)2633-2645(2018 08)
Matsui T,Jiang P,Nakano S,Sakamaki Y,Yamamoto H,Mizushima N

A membrane fusion protein, Ykt6, regulates epithelial cell migration via microRNA-mediated suppression of Junctional Adhesion Molecule A.
Cell cycle (Georgetown, Tex.)17(14)1812-1831(2018)
Naydenov NG,Joshi S,Feygin A,Saini S,Litovchick L,Ivanov AI

YKT6 expression, exosome release, and survival in non-small cell lung cancer.
Oncotarget7(32)51515-51524(2016 Aug)
Ruiz-Martinez M,Navarro A,Marrades RM,Viñolas N,Santasusagna S,Muñoz C,Ramírez J,Molins L,Monzo M

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Science signaling7(354)rs7(2014 Dec)
Guo Z,Neilson LJ,Zhong H,Murray PS,Zanivan S,Zaidel-Bar R

Possible involvement of CCT5, RGS3, and YKT6 genes up-regulated in p53-mutated tumors in resistance to docetaxel in human breast cancers.
Breast cancer research and treatment101(3)305-15(2007 Mar)
Ooe A,Kato K,Noguchi S

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YKT6 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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