EBI3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	EBI3
Entrez Gene ID	10148
Full Name	Epstein-Barr virus induced 3
Synonyms	IL-27B,IL27B,IL35B
General protein information	Preferred Names Epstein-Barr virus induced 3 Names interleukin-27 subunit beta EBV-induced gene 3 protein Epstein-Barr virus induced gene 3 IL-27 subunit beta IL27 subunit IL35 subunit cytokine receptor epstein-Barr virus-induced gene 3 protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19p13.3
Summary	This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells. [provided by RefSeq, Sep 2008].
Disorder MIM:	605816

mRNA and Protein(s)

mRNA	Protein	Name
NM_005755.3	NP_005746.2	interleukin-27 subunit beta precursor
XM_011527619.1	XP_011525921.1	interleukin-27 subunit beta isoform X1
NM_005755.2	NP_005746.2	interleukin-27 subunit beta precursor
XM_011527619.2	XP_011525921.1	interleukin-27 subunit beta isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	EBI3	NP_005746.2
Danio rerio (zebrafish)	ebi3	NP_001106980.1
Pan troglodytes (chimpanzee)	EBI3	XP_001138182.1
Canis lupus familiaris (dog)	EBI3	XP_542161.3
Xenopus tropicalis (tropical clawed frog)	ebi3	XP_002934057.1
Bos taurus (cattle)	EBI3	NP_001093835.1
Mus musculus (house mouse)	Ebi3	NP_056581.1
Rattus norvegicus (Norway rat)	Ebi3	NP_001102891.1

Gene Ontology
Bibliography

Related articles in PubMed

Interleukin-35 in immune-related diseases: protection or destruction.
Zhang J, Zhang Y, Wang Q, Li C, Deng H, Si C, Xiong H
Immunology157(1)13-20(2019 05)

Decreased Gene Expression of Epstein-Barr Virus-Induced Gene 3 (EBI-3) may Contribute to the Pathogenesis of Rheumatoid Arthritis.
Iranshahi N, Assar S, Amiri SM, Zafari P, Fekri A, Taghadosi M
Immunological investigations48(4)367-377(2019 May)

Genetic polymorphism in association with susceptibility to tuberculosis: a study in a Pakistani population.
Naz A, Aslam MA, Khan AUH, Rasul S, Manzoor H, Iqbal R, Shehzad A, Ali M
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]50(2)429-434(2019 Apr)

Aberrant IL-35 levels in patients with primary Sjogren's syndrome.
Guo J, Gu M, Zhang W, Liu Y, Qian C, Deng A
Scandinavian journal of immunology88(5)e12718(2018 Nov)

Mesenchymal stem cells overexpressing IL-35: a novel immunosuppressive strategy and therapeutic target for inducing transplant tolerance.
Guo H, Li B, Wang W, Zhao N, Gao H
Stem cell research & therapy9(1)254(2018 09)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following EBI3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EBI3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu17365	NM_005755.3 Latest version!	Homo sapiens Epstein-Barr virus induced 3 (EBI3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu17365	XM_011527619.2 Latest version!	Homo sapiens Epstein-Barr virus induced 3 (EBI3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
View Old Accession Versions >>
OHu17365	NM_005755.2	Homo sapiens Epstein-Barr virus induced 3 (EBI3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu17365	XM_011527619.1	Homo sapiens Epstein-Barr virus induced 3 (EBI3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

EBI3 ( NM_005755.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005746.2 Homo sapiens Epstein-Barr virus induced 3 (EBI3), mRNA.

Price & Availability↑

CloneID	OHu17365
Clone ID Related Accession (Same CDS sequence)	NM_005755.3 , XM_011527619.1 , NM_005755.2 , XM_011527619.2
Accession Version	NM_005755.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 690bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577721600000
Organism	Homo sapiens(human)
Product	interleukin-27 subunit beta precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC005578.1. On Nov 26, 2018 this sequence version replaced NM_005755.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC015364.1, SRR1163657.205051.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000221847.6/ ENSP00000221847.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGACCCCGC AGCTTCTCCT GGCCCTTGTC CTCTGGGCCA GCTGCCCGCC CTGCAGTGGA 
AGGAAAGGGC CCCCAGCAGC TCTGACACTG CCCCGGGTGC AATGCCGAGC CTCTCGGTAC 
CCGATCGCCG TGGATTGCTC CTGGACCCTG CCGCCTGCTC CAAACTCCAC CAGCCCCGTG 
TCCTTCATTG CCACGTACAG GCTCGGCATG GCTGCCCGGG GCCACAGCTG GCCCTGCCTG 
CAGCAGACGC CAACGTCCAC CAGCTGCACC ATCACGGATG TCCAGCTGTT CTCCATGGCT 
CCCTACGTGC TCAATGTCAC CGCCGTCCAC CCCTGGGGCT CCAGCAGCAG CTTCGTGCCT 
TTCATAACAG AGCACATCAT CAAGCCCGAC CCTCCAGAAG GCGTGCGCCT AAGCCCCCTC 
GCTGAGCGCC AGCTACAGGT GCAGTGGGAG CCTCCCGGGT CCTGGCCCTT CCCAGAGATC 
TTCTCACTGA AGTACTGGAT CCGTTACAAG CGTCAGGGAG CTGCGCGCTT CCACCGGGTG 
GGGCCCATTG AAGCCACGTC CTTCATCCTC AGGGCTGTGC GGCCCCGAGC CAGGTACTAC 
GTCCAAGTGG CGGCTCAGGA CCTCACAGAC TACGGGGAAC TGAGTGACTG GAGTCTCCCC 
GCCACTGCCA CAATGAGCCT GGGCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005746.2
CDS	29..718
Translation	MTPQLLLALVLWASCPPCSGRKGPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATATMSLGK

Target ORF information:

RefSeq Version	NM_005755.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Epstein-Barr virus induced 3 (EBI3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005755.3

ORF Insert Sequence:

ATGACCCCGC AGCTTCTCCT GGCCCTTGTC CTCTGGGCCA GCTGCCCGCC CTGCAGTGGA 
AGGAAAGGGC CCCCAGCAGC TCTGACACTG CCCCGGGTGC AATGCCGAGC CTCTCGGTAC 
CCGATCGCCG TGGATTGCTC CTGGACCCTG CCGCCTGCTC CAAACTCCAC CAGCCCCGTG 
TCCTTCATTG CCACGTACAG GCTCGGCATG GCTGCCCGGG GCCACAGCTG GCCCTGCCTG 
CAGCAGACGC CAACGTCCAC CAGCTGCACC ATCACGGATG TCCAGCTGTT CTCCATGGCT 
CCCTACGTGC TCAATGTCAC CGCCGTCCAC CCCTGGGGCT CCAGCAGCAG CTTCGTGCCT 
TTCATAACAG AGCACATCAT CAAGCCCGAC CCTCCAGAAG GCGTGCGCCT AAGCCCCCTC 
GCTGAGCGCC AGCTACAGGT GCAGTGGGAG CCTCCCGGGT CCTGGCCCTT CCCAGAGATC 
TTCTCACTGA AGTACTGGAT CCGTTACAAG CGTCAGGGAG CTGCGCGCTT CCACCGGGTG 
GGGCCCATTG AAGCCACGTC CTTCATCCTC AGGGCTGTGC GGCCCCGAGC CAGGTACTAC 
GTCCAAGTGG CGGCTCAGGA CCTCACAGAC TACGGGGAAC TGAGTGACTG GAGTCTCCCC 
GCCACTGCCA CAATGAGCCT GGGCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EBI3 ( NM_005755.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_005746.2 Homo sapiens Epstein-Barr virus induced 3 (EBI3), mRNA.

Price & Availability↑

CloneID	OHu17365
Clone ID Related Accession (Same CDS sequence)	NM_005755.3 , XM_011527619.1 , NM_005755.2 , XM_011527619.2
Accession Version	NM_005755.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 690bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1507996800000
Organism	Homo sapiens(human)
Product	interleukin-27 subunit beta precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from L08187.1. On Jun 29, 2001 this sequence version replaced NM_005755.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.376789.1, BC015364.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCCCGC AGCTTCTCCT GGCCCTTGTC CTCTGGGCCA GCTGCCCGCC CTGCAGTGGA 
AGGAAAGGGC CCCCAGCAGC TCTGACACTG CCCCGGGTGC AATGCCGAGC CTCTCGGTAC 
CCGATCGCCG TGGATTGCTC CTGGACCCTG CCGCCTGCTC CAAACTCCAC CAGCCCCGTG 
TCCTTCATTG CCACGTACAG GCTCGGCATG GCTGCCCGGG GCCACAGCTG GCCCTGCCTG 
CAGCAGACGC CAACGTCCAC CAGCTGCACC ATCACGGATG TCCAGCTGTT CTCCATGGCT 
CCCTACGTGC TCAATGTCAC CGCCGTCCAC CCCTGGGGCT CCAGCAGCAG CTTCGTGCCT 
TTCATAACAG AGCACATCAT CAAGCCCGAC CCTCCAGAAG GCGTGCGCCT AAGCCCCCTC 
GCTGAGCGCC AGCTACAGGT GCAGTGGGAG CCTCCCGGGT CCTGGCCCTT CCCAGAGATC 
TTCTCACTGA AGTACTGGAT CCGTTACAAG CGTCAGGGAG CTGCGCGCTT CCACCGGGTG 
GGGCCCATTG AAGCCACGTC CTTCATCCTC AGGGCTGTGC GGCCCCGAGC CAGGTACTAC 
GTCCAAGTGG CGGCTCAGGA CCTCACAGAC TACGGGGAAC TGAGTGACTG GAGTCTCCCC 
GCCACTGCCA CAATGAGCCT GGGCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005746.2
CDS	9..698
Translation	MTPQLLLALVLWASCPPCSGRKGPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATATMSLGK

Target ORF information:

RefSeq Version	NM_005755.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Epstein-Barr virus induced 3 (EBI3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005755.2

ORF Insert Sequence:

ATGACCCCGC AGCTTCTCCT GGCCCTTGTC CTCTGGGCCA GCTGCCCGCC CTGCAGTGGA 
AGGAAAGGGC CCCCAGCAGC TCTGACACTG CCCCGGGTGC AATGCCGAGC CTCTCGGTAC 
CCGATCGCCG TGGATTGCTC CTGGACCCTG CCGCCTGCTC CAAACTCCAC CAGCCCCGTG 
TCCTTCATTG CCACGTACAG GCTCGGCATG GCTGCCCGGG GCCACAGCTG GCCCTGCCTG 
CAGCAGACGC CAACGTCCAC CAGCTGCACC ATCACGGATG TCCAGCTGTT CTCCATGGCT 
CCCTACGTGC TCAATGTCAC CGCCGTCCAC CCCTGGGGCT CCAGCAGCAG CTTCGTGCCT 
TTCATAACAG AGCACATCAT CAAGCCCGAC CCTCCAGAAG GCGTGCGCCT AAGCCCCCTC 
GCTGAGCGCC AGCTACAGGT GCAGTGGGAG CCTCCCGGGT CCTGGCCCTT CCCAGAGATC 
TTCTCACTGA AGTACTGGAT CCGTTACAAG CGTCAGGGAG CTGCGCGCTT CCACCGGGTG 
GGGCCCATTG AAGCCACGTC CTTCATCCTC AGGGCTGTGC GGCCCCGAGC CAGGTACTAC 
GTCCAAGTGG CGGCTCAGGA CCTCACAGAC TACGGGGAAC TGAGTGACTG GAGTCTCCCC 
GCCACTGCCA CAATGAGCCT GGGCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EBI3 ( XM_011527619.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011525921.1 Homo sapiens Epstein-Barr virus induced 3 (EBI3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu17365
Clone ID Related Accession (Same CDS sequence)	NM_005755.3 , XM_011527619.1 , NM_005755.2 , XM_011527619.2
Accession Version	XM_011527619.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 690bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1426003200000
Organism	Homo sapiens(Human)
Product	interleukin-27 subunit beta isoform X1
Comment

ATGACCCCGC AGCTTCTCCT GGCCCTTGTC CTCTGGGCCA GCTGCCCGCC CTGCAGTGGA 
AGGAAAGGGC CCCCAGCAGC TCTGACACTG CCCCGGGTGC AATGCCGAGC CTCTCGGTAC 
CCGATCGCCG TGGATTGCTC CTGGACCCTG CCGCCTGCTC CAAACTCCAC CAGCCCCGTG 
TCCTTCATTG CCACGTACAG GCTCGGCATG GCTGCCCGGG GCCACAGCTG GCCCTGCCTG 
CAGCAGACGC CAACGTCCAC CAGCTGCACC ATCACGGATG TCCAGCTGTT CTCCATGGCT 
CCCTACGTGC TCAATGTCAC CGCCGTCCAC CCCTGGGGCT CCAGCAGCAG CTTCGTGCCT 
TTCATAACAG AGCACATCAT CAAGCCCGAC CCTCCAGAAG GCGTGCGCCT AAGCCCCCTC 
GCTGAGCGCC AGCTACAGGT GCAGTGGGAG CCTCCCGGGT CCTGGCCCTT CCCAGAGATC 
TTCTCACTGA AGTACTGGAT CCGTTACAAG CGTCAGGGAG CTGCGCGCTT CCACCGGGTG 
GGGCCCATTG AAGCCACGTC CTTCATCCTC AGGGCTGTGC GGCCCCGAGC CAGGTACTAC 
GTCCAAGTGG CGGCTCAGGA CCTCACAGAC TACGGGGAAC TGAGTGACTG GAGTCTCCCC 
GCCACTGCCA CAATGAGCCT GGGCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011525921.1
Translation	MTPQLLLALVLWASCPPCSGRKGPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATATMSLGK

Target ORF information:

RefSeq Version	XM_011527619.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens Epstein-Barr virus induced 3 (EBI3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011527619.1

ORF Insert Sequence:

ATGACCCCGC AGCTTCTCCT GGCCCTTGTC CTCTGGGCCA GCTGCCCGCC CTGCAGTGGA 
AGGAAAGGGC CCCCAGCAGC TCTGACACTG CCCCGGGTGC AATGCCGAGC CTCTCGGTAC 
CCGATCGCCG TGGATTGCTC CTGGACCCTG CCGCCTGCTC CAAACTCCAC CAGCCCCGTG 
TCCTTCATTG CCACGTACAG GCTCGGCATG GCTGCCCGGG GCCACAGCTG GCCCTGCCTG 
CAGCAGACGC CAACGTCCAC CAGCTGCACC ATCACGGATG TCCAGCTGTT CTCCATGGCT 
CCCTACGTGC TCAATGTCAC CGCCGTCCAC CCCTGGGGCT CCAGCAGCAG CTTCGTGCCT 
TTCATAACAG AGCACATCAT CAAGCCCGAC CCTCCAGAAG GCGTGCGCCT AAGCCCCCTC 
GCTGAGCGCC AGCTACAGGT GCAGTGGGAG CCTCCCGGGT CCTGGCCCTT CCCAGAGATC 
TTCTCACTGA AGTACTGGAT CCGTTACAAG CGTCAGGGAG CTGCGCGCTT CCACCGGGTG 
GGGCCCATTG AAGCCACGTC CTTCATCCTC AGGGCTGTGC GGCCCCGAGC CAGGTACTAC 
GTCCAAGTGG CGGCTCAGGA CCTCACAGAC TACGGGGAAC TGAGTGACTG GAGTCTCCCC 
GCCACTGCCA CAATGAGCCT GGGCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EBI3 ( XM_011527619.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011525921.1 Homo sapiens Epstein-Barr virus induced 3 (EBI3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu17365
Clone ID Related Accession (Same CDS sequence)	NM_005755.3 , XM_011527619.1 , NM_005755.2 , XM_011527619.2
Accession Version	XM_011527619.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 690bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	interleukin-27 subunit beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011527619.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCCCGC AGCTTCTCCT GGCCCTTGTC CTCTGGGCCA GCTGCCCGCC CTGCAGTGGA 
AGGAAAGGGC CCCCAGCAGC TCTGACACTG CCCCGGGTGC AATGCCGAGC CTCTCGGTAC 
CCGATCGCCG TGGATTGCTC CTGGACCCTG CCGCCTGCTC CAAACTCCAC CAGCCCCGTG 
TCCTTCATTG CCACGTACAG GCTCGGCATG GCTGCCCGGG GCCACAGCTG GCCCTGCCTG 
CAGCAGACGC CAACGTCCAC CAGCTGCACC ATCACGGATG TCCAGCTGTT CTCCATGGCT 
CCCTACGTGC TCAATGTCAC CGCCGTCCAC CCCTGGGGCT CCAGCAGCAG CTTCGTGCCT 
TTCATAACAG AGCACATCAT CAAGCCCGAC CCTCCAGAAG GCGTGCGCCT AAGCCCCCTC 
GCTGAGCGCC AGCTACAGGT GCAGTGGGAG CCTCCCGGGT CCTGGCCCTT CCCAGAGATC 
TTCTCACTGA AGTACTGGAT CCGTTACAAG CGTCAGGGAG CTGCGCGCTT CCACCGGGTG 
GGGCCCATTG AAGCCACGTC CTTCATCCTC AGGGCTGTGC GGCCCCGAGC CAGGTACTAC 
GTCCAAGTGG CGGCTCAGGA CCTCACAGAC TACGGGGAAC TGAGTGACTG GAGTCTCCCC 
GCCACTGCCA CAATGAGCCT GGGCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011525921.1
CDS	258..947
Translation	MTPQLLLALVLWASCPPCSGRKGPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATATMSLGK

Target ORF information:

RefSeq Version	XM_011527619.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Epstein-Barr virus induced 3 (EBI3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011527619.2

ORF Insert Sequence:

ATGACCCCGC AGCTTCTCCT GGCCCTTGTC CTCTGGGCCA GCTGCCCGCC CTGCAGTGGA 
AGGAAAGGGC CCCCAGCAGC TCTGACACTG CCCCGGGTGC AATGCCGAGC CTCTCGGTAC 
CCGATCGCCG TGGATTGCTC CTGGACCCTG CCGCCTGCTC CAAACTCCAC CAGCCCCGTG 
TCCTTCATTG CCACGTACAG GCTCGGCATG GCTGCCCGGG GCCACAGCTG GCCCTGCCTG 
CAGCAGACGC CAACGTCCAC CAGCTGCACC ATCACGGATG TCCAGCTGTT CTCCATGGCT 
CCCTACGTGC TCAATGTCAC CGCCGTCCAC CCCTGGGGCT CCAGCAGCAG CTTCGTGCCT 
TTCATAACAG AGCACATCAT CAAGCCCGAC CCTCCAGAAG GCGTGCGCCT AAGCCCCCTC 
GCTGAGCGCC AGCTACAGGT GCAGTGGGAG CCTCCCGGGT CCTGGCCCTT CCCAGAGATC 
TTCTCACTGA AGTACTGGAT CCGTTACAAG CGTCAGGGAG CTGCGCGCTT CCACCGGGTG 
GGGCCCATTG AAGCCACGTC CTTCATCCTC AGGGCTGTGC GGCCCCGAGC CAGGTACTAC 
GTCCAAGTGG CGGCTCAGGA CCTCACAGAC TACGGGGAAC TGAGTGACTG GAGTCTCCCC 
GCCACTGCCA CAATGAGCCT GGGCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Interleukin-35 in immune-related diseases: protection or destruction.
Immunology157(1)13-20(2019 05)
Zhang J,Zhang Y,Wang Q,Li C,Deng H,Si C,Xiong H

Decreased Gene Expression of Epstein-Barr Virus-Induced Gene 3 (EBI-3) may Contribute to the Pathogenesis of Rheumatoid Arthritis.
Immunological investigations48(4)367-377(2019 May)
shahi N,Assar S,Amiri SM,Zafari P,Fekri A,Taghadosi M

Genetic polymorphism in association with susceptibility to tuberculosis: a study in a Pakistani population.
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]50(2)429-434(2019 Apr)
Naz A,Aslam MA,Khan AUH,Rasul S,Manzoor H,Iqbal R,Shehzad A,Ali M

Aberrant IL-35 levels in patients with primary Sjogren's syndrome.
Scandinavian journal of immunology88(5)e12718(2018 Nov)
Guo J,Gu M,Zhang W,Liu Y,Qian C,Deng A

Mesenchymal stem cells overexpressing IL-35: a novel immunosuppressive strategy and therapeutic target for inducing transplant tolerance.
Stem cell research & therapy9(1)254(2018 09)
Guo H,Li B,Wang W,Zhao N,Gao H

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EBI3 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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