| Gene Symbol | APELA |
| Entrez Gene ID | 100506013 |
| Full Name | apelin receptor early endogenous ligand |
| Synonyms | ELA,Ende,tdl |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | This gene encodes a peptide hormone that binds to the Apelin receptor. The encoded protein is required for heart development in zebrafish and has been shown to maintain self-renewal of human embryonic stem cells through activation of the PI3K/AKT pathway. Experiments in human and mouse cell lines point to additional roles for the encoded protein in angiogenesis and regulation of vascular tone. [provided by RefSeq, Jul 2016]. |
| Disorder MIM: |
User Manual