MYL2 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	MYL2
Entrez Gene ID	416874
Full Name	myosin, light chain 2, regulatory, cardiac, slow
Synonyms	G2,MLC-2A,MLC2
General protein information	Preferred Names myosin, light chain 2, regulatory, cardiac, slow Names myosin regulatory light chain 2A, cardiac muscle isoform cardiac muscle isoform light polypeptide 2 myosin light chain 2 myosin, light polypeptide 2, regulatory, cardiac, slow
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001271929.1	NP_001258858.1	myosin regulatory light chain 2A, cardiac muscle isoform

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Myl2	NP_001030329.2
Gallus gallus (chicken)	MYL2	NP_001258858.1
Canis lupus familiaris (dog)	MYL2	NP_001003069.1
Danio rerio (zebrafish)	myl2b	NP_001035134.1
Xenopus tropicalis (tropical clawed frog)	myl2	NP_001107717.1
Danio rerio (zebrafish)	LOC100537244	XP_003198611.2
Pan troglodytes (chimpanzee)	MYL2	XP_001144828.2
Mus musculus (house mouse)	Myl2	NP_034991.3
Bos taurus (cattle)	MYL2	NP_001030197.1
Homo sapiens (human)	MYL2	NP_000423.2
Macaca mulatta (Rhesus monkey)	MYL2	XP_001100796.1

Gene Ontology
Bibliography

Related articles in PubMed

A comprehensive collection of chicken cDNAs.
Boardman PE, Sanz-Ezquerro J, Overton IM, Burt DW, Bosch E, Fong WT, Tickle C, Brown WR, Wilson SA, Hubbard SJ
Current biology : CB12(22)1965-9(2002 Nov)

Characterization of 5'-flanking region of heart myosin light chain 2A gene. Structural and functional evidence for promoter activity.
Zarraga AM, Danishefsky K, Deshpande A, Nicholson D, Mendola C, Siddiqui MA
The Journal of biological chemistry261(29)13852-60(1986 Oct)

Isolation and characterization of the chicken cardiac myosin light chain (L-2A) gene. Evidence for two additional N-terminal amino acids.
Winter B, Klapthor H, Wiebauer K, Delius H, Arnold HH
The Journal of biological chemistry260(7)4478-83(1985 Apr)

The nucleotide sequence of myosin light chain (L-2A) mRNA from embryonic chicken cardiac muscle tissue.
Arnold HH, Krauskopf M, Siddiqui MA
Nucleic acids research11(4)1123-31(1983 Feb)

Amino acid sequences of the cardiac L-2A, L-2B and gizzard 17 000-Mr light chains of chicken muscle myosin.
Matsuda G, Maita T, Kato Y, Chen JI, Umegane T
FEBS letters135(2)232-6(1981 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MYL2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MYL2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa00648	NM_001271929.1 Latest version!	Gallus gallus myosin, light chain 2, regulatory, cardiac, slow (MYL2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MYL2 ( NM_001271929.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001258858.1 Gallus gallus myosin, light chain 2, regulatory, cardiac, slow (MYL2), mRNA.

Price & Availability↑

CloneID	OGa00648
Clone ID Related Accession (Same CDS sequence)	NM_001271929.1
Accession Version	NM_001271929.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 498bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Gallus gallus(chicken)
Product	myosin regulatory light chain 2A, cardiac muscle isoform
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AADN05000505.1 and BU257651.1. On Dec 14, 2012 this sequence version replaced XM_415166.3. Sequence Note: This RefSeq record was created from transcripts and genomic sequence data because no single transcript from the same breed was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BU144499.1, BU257651.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2201379, SAMEA2201382 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCACCCA AGAAAGCCAA GAAGAGGATT GAAGGTGCGA ATTCCAATGT CTTCTCCATG 
TTCGAGCAGG CCCAGATCCA GGAATTCAAA GAGGCGTTCA CCATCATGGA TCAGAACCGA 
GACGGCTTCA TCGACAAGGC AGACCTGAGA GATACATTTG CTGCACTCGG GCGCCTGAAT 
GTGAAAAACG AGGAGATCGA TGAGATGATC AAGGAGGCAC CTGGCCCAAT CAACTTCACT 
GTGTTCCTCA CCATGTTTGG GGAGAAACTC AAGGGTGCTG ATCCAGAGGA GACGATCCTG 
AACGCGTTCA AGGTGTTTGA TCCGGAGGGC AAAGGGCTGA AATCTGCCTA CATCAAAGAA 
ATGCTGATGA CGCAGGGCGA GAGGTTTTCC CAGGAGGAGA TCGATCAGAT GTTTGCTGCC 
TTCCCTCCAG ACGTCTCCGG CAACCTCGAC TACAAAAACC TCGTCCACGT CATCACACAC 
GGAGAGGAGA AGGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258858.1
CDS	64..561
Translation	MAPKKAKKRIEGANSNVFSMFEQAQIQEFKEAFTIMDQNRDGFIDKADLRDTFAALGRLNVKNEEIDEMIKEAPGPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGLKSAYIKEMLMTQGERFSQEEIDQMFAAFPPDVSGNLDYKNLVHVITHGEEKD

Target ORF information:

RefSeq Version	NM_001271929.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus myosin, light chain 2, regulatory, cardiac, slow (MYL2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271929.1

ORF Insert Sequence:

ATGGCACCCA AGAAAGCCAA GAAGAGGATT GAAGGTGCGA ATTCCAATGT CTTCTCCATG 
TTCGAGCAGG CCCAGATCCA GGAATTCAAA GAGGCGTTCA CCATCATGGA TCAGAACCGA 
GACGGCTTCA TCGACAAGGC AGACCTGAGA GATACATTTG CTGCACTCGG GCGCCTGAAT 
GTGAAAAACG AGGAGATCGA TGAGATGATC AAGGAGGCAC CTGGCCCAAT CAACTTCACT 
GTGTTCCTCA CCATGTTTGG GGAGAAACTC AAGGGTGCTG ATCCAGAGGA GACGATCCTG 
AACGCGTTCA AGGTGTTTGA TCCGGAGGGC AAAGGGCTGA AATCTGCCTA CATCAAAGAA 
ATGCTGATGA CGCAGGGCGA GAGGTTTTCC CAGGAGGAGA TCGATCAGAT GTTTGCTGCC 
TTCCCTCCAG ACGTCTCCGG CAACCTCGAC TACAAAAACC TCGTCCACGT CATCACACAC 
GGAGAGGAGA AGGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A comprehensive collection of chicken cDNAs.
Current biology : CB12(22)1965-9(2002 Nov)
Boardman PE,Sanz-Ezquerro J,Overton IM,Burt DW,Bosch E,Fong WT,Tickle C,Brown WR,Wilson SA,Hubbard SJ

Characterization of 5'-flanking region of heart myosin light chain 2A gene. Structural and functional evidence for promoter activity.
The Journal of biological chemistry261(29)13852-60(1986 Oct)
Zarraga AM,Danishefsky K,Deshpande A,Nicholson D,Mendola C,Siddiqui MA

Isolation and characterization of the chicken cardiac myosin light chain (L-2A) gene. Evidence for two additional N-terminal amino acids.
The Journal of biological chemistry260(7)4478-83(1985 Apr)
Winter B,Klapthor H,Wiebauer K,Delius H,Arnold HH

The nucleotide sequence of myosin light chain (L-2A) mRNA from embryonic chicken cardiac muscle tissue.
Nucleic acids research11(4)1123-31(1983 Feb)
Arnold HH,Krauskopf M,Siddiqui MA

Amino acid sequences of the cardiac L-2A, L-2B and gizzard 17 000-Mr light chains of chicken muscle myosin.
FEBS letters135(2)232-6(1981 Dec)
Matsuda G,Maita T,Kato Y,Chen JI,Umegane T