CRH cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	CRH
Entrez Gene ID	404297
Full Name	corticotropin releasing hormone
Synonyms	CRF,corticoliberin
General protein information	Preferred Names corticotropin releasing hormone Names corticoliberin
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001123031.1	NP_001116503.1	corticoliberin precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	CRH	NP_000747.1
Canis lupus familiaris (dog)	CRH	NP_001014300.2
Pan troglodytes (chimpanzee)	CRH	XP_003951319.1
Macaca mulatta (Rhesus monkey)	CRH	XP_001094433.1
Rattus norvegicus (Norway rat)	Crh	NP_112281.1
Xenopus tropicalis (tropical clawed frog)	crh	XP_004915238.1
Danio rerio (zebrafish)	crhb	NP_001007380.1
Mus musculus (house mouse)	Crh	NP_991338.1
Xenopus tropicalis (tropical clawed frog)	LOC100485597	XP_004915231.1
Gallus gallus (chicken)	CRH	NP_001116503.1

Gene Ontology
Bibliography

Related articles in PubMed

Stress-induced suppression of neuropeptide Y-induced hunger in anorexic chicks involves corticotrophin-releasing factor signalling and the paraventricular nucleus of the hypothalamus.
Wang J, Yi J, Siegel PB, Cline MA, Gilbert ER
Journal of neuroendocrinology29(12)(2017 12)

The balance between stress resilience and vulnerability is regulated by corticotropin-releasing hormone during the critical postnatal period for sensory development.
Cramer T, Kisliouk T, Yeshurun S, Meiri N
Developmental neurobiology75(8)842-53(2015 Aug)

Comparison of brain urocortin-3 and corticotrophin-releasing factor for physiological responses in chicks.
Ogino M, Okumura A, Khan MS, Cline MA, Tachibana T
Physiology & behavior12557-61(2014 Feb)

Effects of cold stress on the messenger ribonucleic acid levels of corticotrophin-releasing hormone and thyrotropin-releasing hormone in hypothalami of broilers.
Wang JT, Wang JW, Xu SW
Poultry science87(5)973-8(2008 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following CRH gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CRH cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa24568	NM_001123031.1 Latest version!	Gallus gallus corticotropin releasing hormone (CRH), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CRH ( NM_001123031.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001116503.1 Gallus gallus corticotropin releasing hormone (CRH), mRNA.

Price & Availability↑

CloneID	OGa24568
Clone ID Related Accession (Same CDS sequence)	NM_001123031.1
Accession Version	NM_001123031.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 504bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1526745600000
Organism	Gallus gallus(chicken)
Product	corticoliberin precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ621492.3. On Apr 8, 2008 this sequence version replaced XM_418279.2. ##Evidence-Data-START## Transcript exon combination :: AJ621492.3 [ECO:0000332] ##Evidence-Data-END##

ATGAAGCTCC AGCCGCTGGT GTGCGCGGGG ATCCTGCTGC TCGCCCTGCT GCCCTGCCAC 
GAGTGCCGAG CGCTCAGCAA GAGCCCGGGA GCCGCCCGCG GGGCTCTGCA GCAGCCCGAT 
TTCTTCCCTC AGCAGCAGCA GCAGCAGCAG CAGCAAACTC TGCCCGTCCT GCTCCGCATG 
GGAGAGGAGT ACTTCCTGCG CCTGGGCCAC CTCACCAAGC GCCCCGCCGG CCCTTTCTCC 
GCCTCCTCCG GCGGCCACCT TCGGCCCGAA GCCTCCGCCG AGTTGTTGCG GGCGGCCGCG 
GCGCAGCTGC AGGGGTCGGG GAGCCCCGAG GGGGACGAAG GAGCGGGGGA GGCGGTGGAG 
AGGGAGAAGC GCTCCGAGGA GCCGCCCATC TCCCTGGACC TGACTTTCCA CCTGCTGCGG 
GAGGTGCTGG AGATGGCCCG CGCCGAGCAG CTGGCGCAGC AAGCCCACAG CAACAGGAAA 
CTGATGGAAA TCATCGGGAA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001116503.1
CDS	165..668
Translation	MKLQPLVCAGILLLALLPCHECRALSKSPGAARGALQQPDFFPQQQQQQQQQTLPVLLRMGEEYFLRLGHLTKRPAGPFSASSGGHLRPEASAELLRAAAAQLQGSGSPEGDEGAGEAVEREKRSEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEIIGK

Target ORF information:

RefSeq Version	NM_001123031.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus corticotropin releasing hormone (CRH), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001123031.1

ORF Insert Sequence:

ATGAAGCTCC AGCCGCTGGT GTGCGCGGGG ATCCTGCTGC TCGCCCTGCT GCCCTGCCAC 
GAGTGCCGAG CGCTCAGCAA GAGCCCGGGA GCCGCCCGCG GGGCTCTGCA GCAGCCCGAT 
TTCTTCCCTC AGCAGCAGCA GCAGCAGCAG CAGCAAACTC TGCCCGTCCT GCTCCGCATG 
GGAGAGGAGT ACTTCCTGCG CCTGGGCCAC CTCACCAAGC GCCCCGCCGG CCCTTTCTCC 
GCCTCCTCCG GCGGCCACCT TCGGCCCGAA GCCTCCGCCG AGTTGTTGCG GGCGGCCGCG 
GCGCAGCTGC AGGGGTCGGG GAGCCCCGAG GGGGACGAAG GAGCGGGGGA GGCGGTGGAG 
AGGGAGAAGC GCTCCGAGGA GCCGCCCATC TCCCTGGACC TGACTTTCCA CCTGCTGCGG 
GAGGTGCTGG AGATGGCCCG CGCCGAGCAG CTGGCGCAGC AAGCCCACAG CAACAGGAAA 
CTGATGGAAA TCATCGGGAA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Stress-induced suppression of neuropeptide Y-induced hunger in anorexic chicks involves corticotrophin-releasing factor signalling and the paraventricular nucleus of the hypothalamus.
Journal of neuroendocrinology29(12)(2017 12)
Wang J,Yi J,Siegel PB,Cline MA,Gilbert ER

The balance between stress resilience and vulnerability is regulated by corticotropin-releasing hormone during the critical postnatal period for sensory development.
Developmental neurobiology75(8)842-53(2015 Aug)
Cramer T,Kisliouk T,Yeshurun S,Meiri N

Comparison of brain urocortin-3 and corticotrophin-releasing factor for physiological responses in chicks.
Physiology & behavior12557-61(2014 Feb)
Ogino M,Okumura A,Khan MS,Cline MA,Tachibana T

Effects of cold stress on the messenger ribonucleic acid levels of corticotrophin-releasing hormone and thyrotropin-releasing hormone in hypothalami of broilers.
Poultry science87(5)973-8(2008 May)
Wang JT,Wang JW,Xu SW