LRP8 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	LRP8
Entrez Gene ID	396102
Full Name	LDL receptor related protein 8
Synonyms	LR8B
General protein information	Preferred Names LDL receptor related protein 8 Names low-density lipoprotein receptor-related protein 8 LRP-8 apolipoprotein E receptor 2 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_205186.2	NP_990517.1	low-density lipoprotein receptor-related protein 8 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Lrp8	XP_006238632.1
Pan troglodytes (chimpanzee)	LRP8	XP_513416.3
Macaca mulatta (Rhesus monkey)	LRP8	XP_001112940.1
Canis lupus familiaris (dog)	LRP8	XP_546704.3
Gallus gallus (chicken)	LRP8	NP_990517.1
Danio rerio (zebrafish)	apoer2	NP_001243322.1
Homo sapiens (human)	LRP8	NP_004622.2
Xenopus tropicalis (tropical clawed frog)	lrp8	XP_004914072.1
Mus musculus (house mouse)	Lrp8	NP_001074395.1
Bos taurus (cattle)	LRP8	NP_001091034.1

Gene Ontology
Bibliography

Related articles in PubMed

Reelin/DAB-1 signaling in the embryonic limb regulates the chondrogenic differentiation of digit mesodermal progenitors.
Diaz-Mendoza MJ, Lorda-Diez CI, Montero JA, Garcia-Porrero JA, Hurle JM
Journal of cellular physiology229(10)1397-404(2014 Oct)

Small non-coding RNA profiling and the role of piRNA pathway genes in the protection of chicken primordial germ cells.
Rengaraj D, Lee SI, Park TS, Lee HJ, Kim YM, Sohn YA, Jung M, Noh SJ, Jung H, Han JY
BMC genomics15757(2014 Sep)

Foxp1 and lhx1 coordinate motor neuron migration with axon trajectory choice by gating Reelin signalling.
Palmesino E, Rousso DL, Kao TJ, Klar A, Laufer E, Uemura O, Okamoto H, Novitch BG, Kania A
PLoS biology8(8)e1000446(2010 Aug)

Low-density lipoprotein receptor-related protein 8 gene association with egg traits in dwarf chickens.
Yao JF, Chen ZX, Xu GY, Wang XL, Ning ZH, Zheng JX, Qu LJ, Yang N
Poultry science89(5)883-6(2010 May)

Alternative splicing in the ligand binding domain of mouse ApoE receptor-2 produces receptor variants binding reelin but not alpha 2-macroglobulin.
Brandes C, Kahr L, Stockinger W, Hiesberger T, Schneider WJ, Nimpf J
The Journal of biological chemistry276(25)22160-9(2001 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following LRP8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LRP8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa00270	NM_205186.2 Latest version!	Gallus gallus LDL receptor related protein 8 (LRP8), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LRP8 ( NM_205186.2 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_990517.1 Gallus gallus LDL receptor related protein 8 (LRP8), mRNA.

Price & Availability↑

CloneID	OGa00270
Clone ID Related Accession (Same CDS sequence)	NM_205186.2
Accession Version	NM_205186.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2754bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1568995200000
Organism	Gallus gallus(chicken)
Product	low-density lipoprotein receptor-related protein 8 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X97001.1. On Nov 6, 2016 this sequence version replaced NM_205186.1. ##Evidence-Data-START## Transcript exon combination :: X97001.1 [ECO:0000332] ##Evidence-Data-END##

ATGTGCCGGC CTGCGCTCGC CCGGCTGCTG CTCCTCCAGC TGCTGCTGCT GAAGCTGTAC 
CTCGGCAAAG GAGCCATGAA GGAGTGCGAT AAGGACCAGT TCCAGTGCCG GAACGAGCGG 
TGCATCCCCG CCGTGTGGGC GTGCGACGAA GACAACGACT GCTCGGATAA CAGCGACGAG 
GCTGATTGCC CAAAGAAAAC TTGTGCTGAA ACGGATTTCG CTTGTGACAA CGGGCACTGC 
ATCCCAGATA GGTGGAAGTG TGACGGCGAA GAAGAATGCT CTGATGGGTC GGATGAATCA 
GAAGCAGCAT GCACCAAGCA AGTATGCCCA GCTGAAAAAA TTAGCTGTGG AGACTTAAGC 
AACAAATGTA TCCCGTCGTC CTGGAGATGT GATGGGCAGA AGGACTGTGA AAGCGGGATT 
GATGAGGCTG GTTGTGCTCC TGCTTGTTCT CCTGATGAGT TCCAGTGCAG TAACAAGACG 
TGCATCTCCA TCAACTTCGT GTGTGATGGT TACAACAACT GTGGTGATGG CAGTGATGAA 
AAGAAATGCT CCCCTCTGAC CTGCAGCCCC AATGAGTTCC AGTGCAACAA CAGCGTGTGC 
ATCCCACAGC TGTGGGTCTG TGACAACCAG GCAGACTGTG AGGACCATTC GGATGAGTCC 
ATAGAGAGGT GTGGCTATGA TGCCAAGGCC TTCAACACCT GTGCTGCTCA CGAGTTCCAG 
TGTGGCAATG GCGAATGCAT CCTCCTTAAC TGGAAGTGTG ATGGGGACGA AGACTGCAAG 
GACAAATCTG ACGAGCAGGA CTGCCCTCTG GTGACCTGCA GACCGGATGA ATTCCAGTGC 
GGGGATGGGA CCTGCATCCA TGGAGCAAAG CAGTGTGACA AAGTGCACGA CTGTCCTGAC 
AACAGTGACG AGGCAGGCTG TGTCCAAGAG TCAGCATGTG AAAGTCCCAG CAAGTTTCAG 
TGTAAGAGTG GAGAGTGCAT TGACGGAGGC AAAGTGTGCG ATTTACATAG AGACTGCAGG 
GACTGGTCTG ACGAGCCTCT GAAAGAATGT GGTATTAACG AATGCTCTCT GAACAACGGT 
GGCTGCTCAC ACATATGCAA AGACTTGAAG ATAGGCTACG AATGTGAATG CCCGCCCGGA 
TACAAGCTTC TGGATAAAAA AACGTGTGGA GACATAGATG AATGTGAGAA TCCAGACGCT 
TGTAGCCAGA TCTGCATTAA TTACAAGGGG GACTACAAAT GTGAGTGCTA CGAGGGATAC 
GAGATGGACA CCCTGTCCAA GAACTGCAAA GCTGTAGGAA AGAGTCCCTA CCTGATCTTC 
ACCAACCGCC ACGAGGTCCG CAAGATAGAC CTGGTGAAAA GGGACTATTC TCGCATCATT 
CCCATGCTGA AAAATGTCGT GGCGCTGGAT GTGGAGGTGG CAACAAACAG AATATACTGG 
TGTGATTTGT TCTACCGAAA AATCTACAGT GCCTACATAG ACAAAGCGAG CGACACAGCG 
GAGCAGGTGA TTCTCATAGA CAGCCAGCTA AACTCTCCTG AAGGGGTGGC GATTGACTGG 
GTTCATAAGA ATATCTACTG GACAGATTCT GGAAACAAGA CTATCTCAGT GGCCACTGCA 
GACGGGAGCA GGAGGAGGAC AGTTTTTAAC AGCGACCTCA GTGAGCCGAG AGCCATTGCT 
GTTGATCCCA CACGGAGGTT CATGTACTGG TCTGACTGGG GAGACAAAGC GAAGATTGAG 
AAAGCAGGCC TCAATGGTGT GGGGCGGCAA GTGCTGGTGT CTGACAACAT TGAGTGGCCA 
AACGGCATCA CGCTTGATTT GCTGAATCAG CGTCTCTACT GGGTGGACTC CAAATTGCAT 
TCACTCTCCT GCATTGATTT CAATGGCAGC AACAGAGAAG TTCTGATCTC TTCCATTGAT 
GATCTGAGCC ATCCGTTCGG CTTAGCAGTG TTTGAGGACA GAGTGTTCTG GACTGACCTG 
GAGAATGAAG CAATCTTCAG TGCCAACAGG CTGAGTGGCT TGGACATCTC TGTTTTAGCA 
GAAAATCTCA ATAATCCTCA TGACATCGTT GTATTTCATG AATTAAAGCA GCCCAAAGCT 
CCAGACTCCT GTGAGCTCAG CCCCCAGCCA AATGGAGGCT GCGAGTATTT GTGTCTTCCT 
GCACCTCACA TCTCTCCCCG TTCCCCCAAG TTTACCTGCG CCTGTCCTGA TAACATGTGG 
CTGGGTCCTG ACATGAAAAA ATGCTACAAA GAACTTCCAA CCACTCCAGC TACAGTAGAG 
GTTCCTACAA CCACAACATC TCATCCTGCT GCTACCTCCA CTGTGACTGT AACTGGCAGC 
GCCAACACCA CCACCGCCGT CATCCCCAGA GCTGTATCGG AAGCCACGAC TGCCATCCCG 
AGTTCTCATT CAACCACATC GCTCCTCATA GATTCTGAGA TGACCACTGG AAACAGCAAC 
CTATCACAGC ACTATTCAAA TAATGGTCAA GGCTTTGATT CAACTGTGAC AGCAGCTGTG 
ATTGGAATTG TCATTCCTGT TGTGGTTATT GGCTTGCTGT GCATGGGGGG ATACCTCATC 
TGGAGAAACT GGAAACGGAA GAACACTAAA AGCATGAACT TCGATAATCC AGTATATAGG 
AAGACAACAG AAGAGGAAGA TGAAGATGAA ATCCATATTG GTCGGACTGC CCAAATTGGA 
CATGTCTATC CAGCACGTGT AGCACTGAGC TTAGAAGACG ATGGGTTGCC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_990517.1
CDS	25..2778
Translation	MCRPALARLLLLQLLLLKLYLGKGAMKECDKDQFQCRNERCIPAVWACDEDNDCSDNSDEADCPKKTCAETDFACDNGHCIPDRWKCDGEEECSDGSDESEAACTKQVCPAEKISCGDLSNKCIPSSWRCDGQKDCESGIDEAGCAPACSPDEFQCSNKTCISINFVCDGYNNCGDGSDEKKCSPLTCSPNEFQCNNSVCIPQLWVCDNQADCEDHSDESIERCGYDAKAFNTCAAHEFQCGNGECILLNWKCDGDEDCKDKSDEQDCPLVTCRPDEFQCGDGTCIHGAKQCDKVHDCPDNSDEAGCVQESACESPSKFQCKSGECIDGGKVCDLHRDCRDWSDEPLKECGINECSLNNGGCSHICKDLKIGYECECPPGYKLLDKKTCGDIDECENPDACSQICINYKGDYKCECYEGYEMDTLSKNCKAVGKSPYLIFTNRHEVRKIDLVKRDYSRIIPMLKNVVALDVEVATNRIYWCDLFYRKIYSAYIDKASDTAEQVILIDSQLNSPEGVAIDWVHKNIYWTDSGNKTISVATADGSRRRTVFNSDLSEPRAIAVDPTRRFMYWSDWGDKAKIEKAGLNGVGRQVLVSDNIEWPNGITLDLLNQRLYWVDSKLHSLSCIDFNGSNREVLISSIDDLSHPFGLAVFEDRVFWTDLENEAIFSANRLSGLDISVLAENLNNPHDIVVFHELKQPKAPDSCELSPQPNGGCEYLCLPAPHISPRSPKFTCACPDNMWLGPDMKKCYKELPTTPATVEVPTTTTSHPAATSTVTVTGSANTTTAVIPRAVSEATTAIPSSHSTTSLLIDSEMTTGNSNLSQHYSNNGQGFDSTVTAAVIGIVIPVVVIGLLCMGGYLIWRNWKRKNTKSMNFDNPVYRKTTEEEDEDEIHIGRTAQIGHVYPARVALSLEDDGLP

Target ORF information:

RefSeq Version	NM_205186.2
Organism	Gallus gallus(chicken)
Definition	Gallus gallus LDL receptor related protein 8 (LRP8), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_205186.2

ORF Insert Sequence:

ATGTGCCGGC CTGCGCTCGC CCGGCTGCTG CTCCTCCAGC TGCTGCTGCT GAAGCTGTAC 
CTCGGCAAAG GAGCCATGAA GGAGTGCGAT AAGGACCAGT TCCAGTGCCG GAACGAGCGG 
TGCATCCCCG CCGTGTGGGC GTGCGACGAA GACAACGACT GCTCGGATAA CAGCGACGAG 
GCTGATTGCC CAAAGAAAAC TTGTGCTGAA ACGGATTTCG CTTGTGACAA CGGGCACTGC 
ATCCCAGATA GGTGGAAGTG TGACGGCGAA GAAGAATGCT CTGATGGGTC GGATGAATCA 
GAAGCAGCAT GCACCAAGCA AGTATGCCCA GCTGAAAAAA TTAGCTGTGG AGACTTAAGC 
AACAAATGTA TCCCGTCGTC CTGGAGATGT GATGGGCAGA AGGACTGTGA AAGCGGGATT 
GATGAGGCTG GTTGTGCTCC TGCTTGTTCT CCTGATGAGT TCCAGTGCAG TAACAAGACG 
TGCATCTCCA TCAACTTCGT GTGTGATGGT TACAACAACT GTGGTGATGG CAGTGATGAA 
AAGAAATGCT CCCCTCTGAC CTGCAGCCCC AATGAGTTCC AGTGCAACAA CAGCGTGTGC 
ATCCCACAGC TGTGGGTCTG TGACAACCAG GCAGACTGTG AGGACCATTC GGATGAGTCC 
ATAGAGAGGT GTGGCTATGA TGCCAAGGCC TTCAACACCT GTGCTGCTCA CGAGTTCCAG 
TGTGGCAATG GCGAATGCAT CCTCCTTAAC TGGAAGTGTG ATGGGGACGA AGACTGCAAG 
GACAAATCTG ACGAGCAGGA CTGCCCTCTG GTGACCTGCA GACCGGATGA ATTCCAGTGC 
GGGGATGGGA CCTGCATCCA TGGAGCAAAG CAGTGTGACA AAGTGCACGA CTGTCCTGAC 
AACAGTGACG AGGCAGGCTG TGTCCAAGAG TCAGCATGTG AAAGTCCCAG CAAGTTTCAG 
TGTAAGAGTG GAGAGTGCAT TGACGGAGGC AAAGTGTGCG ATTTACATAG AGACTGCAGG 
GACTGGTCTG ACGAGCCTCT GAAAGAATGT GGTATTAACG AATGCTCTCT GAACAACGGT 
GGCTGCTCAC ACATATGCAA AGACTTGAAG ATAGGCTACG AATGTGAATG CCCGCCCGGA 
TACAAGCTTC TGGATAAAAA AACGTGTGGA GACATAGATG AATGTGAGAA TCCAGACGCT 
TGTAGCCAGA TCTGCATTAA TTACAAGGGG GACTACAAAT GTGAGTGCTA CGAGGGATAC 
GAGATGGACA CCCTGTCCAA GAACTGCAAA GCTGTAGGAA AGAGTCCCTA CCTGATCTTC 
ACCAACCGCC ACGAGGTCCG CAAGATAGAC CTGGTGAAAA GGGACTATTC TCGCATCATT 
CCCATGCTGA AAAATGTCGT GGCGCTGGAT GTGGAGGTGG CAACAAACAG AATATACTGG 
TGTGATTTGT TCTACCGAAA AATCTACAGT GCCTACATAG ACAAAGCGAG CGACACAGCG 
GAGCAGGTGA TTCTCATAGA CAGCCAGCTA AACTCTCCTG AAGGGGTGGC GATTGACTGG 
GTTCATAAGA ATATCTACTG GACAGATTCT GGAAACAAGA CTATCTCAGT GGCCACTGCA 
GACGGGAGCA GGAGGAGGAC AGTTTTTAAC AGCGACCTCA GTGAGCCGAG AGCCATTGCT 
GTTGATCCCA CACGGAGGTT CATGTACTGG TCTGACTGGG GAGACAAAGC GAAGATTGAG 
AAAGCAGGCC TCAATGGTGT GGGGCGGCAA GTGCTGGTGT CTGACAACAT TGAGTGGCCA 
AACGGCATCA CGCTTGATTT GCTGAATCAG CGTCTCTACT GGGTGGACTC CAAATTGCAT 
TCACTCTCCT GCATTGATTT CAATGGCAGC AACAGAGAAG TTCTGATCTC TTCCATTGAT 
GATCTGAGCC ATCCGTTCGG CTTAGCAGTG TTTGAGGACA GAGTGTTCTG GACTGACCTG 
GAGAATGAAG CAATCTTCAG TGCCAACAGG CTGAGTGGCT TGGACATCTC TGTTTTAGCA 
GAAAATCTCA ATAATCCTCA TGACATCGTT GTATTTCATG AATTAAAGCA GCCCAAAGCT 
CCAGACTCCT GTGAGCTCAG CCCCCAGCCA AATGGAGGCT GCGAGTATTT GTGTCTTCCT 
GCACCTCACA TCTCTCCCCG TTCCCCCAAG TTTACCTGCG CCTGTCCTGA TAACATGTGG 
CTGGGTCCTG ACATGAAAAA ATGCTACAAA GAACTTCCAA CCACTCCAGC TACAGTAGAG 
GTTCCTACAA CCACAACATC TCATCCTGCT GCTACCTCCA CTGTGACTGT AACTGGCAGC 
GCCAACACCA CCACCGCCGT CATCCCCAGA GCTGTATCGG AAGCCACGAC TGCCATCCCG 
AGTTCTCATT CAACCACATC GCTCCTCATA GATTCTGAGA TGACCACTGG AAACAGCAAC 
CTATCACAGC ACTATTCAAA TAATGGTCAA GGCTTTGATT CAACTGTGAC AGCAGCTGTG 
ATTGGAATTG TCATTCCTGT TGTGGTTATT GGCTTGCTGT GCATGGGGGG ATACCTCATC 
TGGAGAAACT GGAAACGGAA GAACACTAAA AGCATGAACT TCGATAATCC AGTATATAGG 
AAGACAACAG AAGAGGAAGA TGAAGATGAA ATCCATATTG GTCGGACTGC CCAAATTGGA 
CATGTCTATC CAGCACGTGT AGCACTGAGC TTAGAAGACG ATGGGTTGCC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Reelin/DAB-1 signaling in the embryonic limb regulates the chondrogenic differentiation of digit mesodermal progenitors.
Journal of cellular physiology229(10)1397-404(2014 Oct)
Diaz-Mendoza MJ,Lorda-Diez CI,Montero JA,Garcia-Porrero JA,Hurle JM

Small non-coding RNA profiling and the role of piRNA pathway genes in the protection of chicken primordial germ cells.
BMC genomics15757(2014 Sep)
Rengaraj D,Lee SI,Park TS,Lee HJ,Kim YM,Sohn YA,Jung M,Noh SJ,Jung H,Han JY

Foxp1 and lhx1 coordinate motor neuron migration with axon trajectory choice by gating Reelin signalling.
PLoS biology8(8)e1000446(2010 Aug)
Palmesino E,Rousso DL,Kao TJ,Klar A,Laufer E,Uemura O,Okamoto H,Novitch BG,Kania A

Low-density lipoprotein receptor-related protein 8 gene association with egg traits in dwarf chickens.
Poultry science89(5)883-6(2010 May)
Yao JF,Chen ZX,Xu GY,Wang XL,Ning ZH,Zheng JX,Qu LJ,Yang N

Alternative splicing in the ligand binding domain of mouse ApoE receptor-2 produces receptor variants binding reelin but not alpha 2-macroglobulin.
The Journal of biological chemistry276(25)22160-9(2001 Jun)
Brandes C,Kahr L,Stockinger W,Hiesberger T,Schneider WJ,Nimpf J

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LRP8 cDNA ORF clone, Gallus gallus(chicken)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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