MIP cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	MIP
Entrez Gene ID	374124
Full Name	major intrinsic protein of lens fiber
General protein information	Preferred Names major intrinsic protein of lens fiber Names lens fiber major intrinsic protein AQP0 MIP26 MP26 aquaporin-0
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_204266.1	NP_989597.1	lens fiber major intrinsic protein

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Aquaporin 0 enhances gap junction coupling via its cell adhesion function and interaction with connexin 50.
Liu J, Xu J, Gu S, Nicholson BJ, Jiang JX
Journal of cell science124(Pt 2)198-206(2011 Jan)

Developmental regulation of the direct interaction between the intracellular loop of connexin 45.6 and the C terminus of major intrinsic protein (aquaporin-0).
Yu XS, Yin X, Lafer EM, Jiang JX
The Journal of biological chemistry280(23)22081-90(2005 Jun)

Interaction of major intrinsic protein (aquaporin-0) with fiber connexins in lens development.
Yu XS, Jiang JX
Journal of cell science117(Pt 6)871-80(2004 Feb)

Partial amino acid sequence of the major intrinsic protein (MIP) of the chicken lens deduced from the nucleotide sequence of a cDNA clone.
Kodama R, Agata K, Mochii M, Eguchi G
Experimental eye research50(6)737-41(1990 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MIP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MIP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa00416	NM_204266.1 Latest version!	Gallus gallus major intrinsic protein of lens fiber (MIP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MIP ( NM_204266.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_989597.1 Gallus gallus major intrinsic protein of lens fiber (MIP), mRNA.

Price & Availability↑

CloneID	OGa00416
Clone ID Related Accession (Same CDS sequence)	NM_204266.1
Accession Version	NM_204266.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 789bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569168000000
Organism	Gallus gallus(chicken)
Product	lens fiber major intrinsic protein
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY078179.1. ##Evidence-Data-START## Transcript exon combination :: AY078179.1 [ECO:0000332] ##Evidence-Data-END##

ATGCGGGAGC TGCGCTCGTC CTCCTTTTGG AGGGCCATCC TGGCCGAGTT CCTGGGCAGC 
CTCCTCTACA CCCTGCTGGG GCTGGGGGCT TCACTGCGCT GGGCCCCGGG CCCCCACGGG 
GTCCTGGGGT CCGCCTTGGC CTTCGGCCTG GCCCAAGCCA CCCTGGTGCA GGCGCTGGGG 
CACGTCAGCG GAGGGCACAT CAACCCGGCC ATCACGCTGG CCTTCCTGCT GGCCTCGCAG 
CTCTCCCTGC CCCGTGCCCT GGGCTACCTG CTGGCTCAGC TGCTGGGTGC CCTGGCGGGG 
GCCGGCGTCC TCTATGGGGT GACACCGGCC GCCGTGCGCG GCACGCTGGG CCTCAGTGCG 
CTGCACCCCA GCGTGGGTCC GGGCCAGGGC ACGGTGGTGG AGCTGCTGCT GACGGCTCAG 
TTCATCCTCT GCGTCTTCGC CAGCTTCGAC GACCGCCATG ACGGGCGCCC TGGCTCTGCT 
GCGCTGCCCG TTGGCTTCTC TCTCGCCCTC GGCCACCTCT TTGGGATCCC ATTCACTGGT 
GCTGGCATGA ACCCCGCGCG GTCCTTTGCG CCCGCTGTCA TCACCCGCAA CTTCACCAAC 
CACTGGGTGT TCTGGGCGGG TCCGCTGCTG GGCGCGGCGC TGGCGGCTCT GCTGTACGAG 
CTGGCGCTGT GTCCGCGGGC GCGCAGCATG GCGGAGCGCC TGGCCGTGCT GCGGGGGGAG 
CCGCCCGCCG CCGCGCCGCC CCCCGAACCG CCGGCGGAAC CGCTGGAGCT GAAGACGCAG 
GGGCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_989597.1
CDS	41..829
Translation	MRELRSSSFWRAILAEFLGSLLYTLLGLGASLRWAPGPHGVLGSALAFGLAQATLVQALGHVSGGHINPAITLAFLLASQLSLPRALGYLLAQLLGALAGAGVLYGVTPAAVRGTLGLSALHPSVGPGQGTVVELLLTAQFILCVFASFDDRHDGRPGSAALPVGFSLALGHLFGIPFTGAGMNPARSFAPAVITRNFTNHWVFWAGPLLGAALAALLYELALCPRARSMAERLAVLRGEPPAAAPPPEPPAEPLELKTQGL

Target ORF information:

RefSeq Version	NM_204266.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus major intrinsic protein of lens fiber (MIP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_204266.1

ORF Insert Sequence:

ATGCGGGAGC TGCGCTCGTC CTCCTTTTGG AGGGCCATCC TGGCCGAGTT CCTGGGCAGC 
CTCCTCTACA CCCTGCTGGG GCTGGGGGCT TCACTGCGCT GGGCCCCGGG CCCCCACGGG 
GTCCTGGGGT CCGCCTTGGC CTTCGGCCTG GCCCAAGCCA CCCTGGTGCA GGCGCTGGGG 
CACGTCAGCG GAGGGCACAT CAACCCGGCC ATCACGCTGG CCTTCCTGCT GGCCTCGCAG 
CTCTCCCTGC CCCGTGCCCT GGGCTACCTG CTGGCTCAGC TGCTGGGTGC CCTGGCGGGG 
GCCGGCGTCC TCTATGGGGT GACACCGGCC GCCGTGCGCG GCACGCTGGG CCTCAGTGCG 
CTGCACCCCA GCGTGGGTCC GGGCCAGGGC ACGGTGGTGG AGCTGCTGCT GACGGCTCAG 
TTCATCCTCT GCGTCTTCGC CAGCTTCGAC GACCGCCATG ACGGGCGCCC TGGCTCTGCT 
GCGCTGCCCG TTGGCTTCTC TCTCGCCCTC GGCCACCTCT TTGGGATCCC ATTCACTGGT 
GCTGGCATGA ACCCCGCGCG GTCCTTTGCG CCCGCTGTCA TCACCCGCAA CTTCACCAAC 
CACTGGGTGT TCTGGGCGGG TCCGCTGCTG GGCGCGGCGC TGGCGGCTCT GCTGTACGAG 
CTGGCGCTGT GTCCGCGGGC GCGCAGCATG GCGGAGCGCC TGGCCGTGCT GCGGGGGGAG 
CCGCCCGCCG CCGCGCCGCC CCCCGAACCG CCGGCGGAAC CGCTGGAGCT GAAGACGCAG 
GGGCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Aquaporin 0 enhances gap junction coupling via its cell adhesion function and interaction with connexin 50.
Journal of cell science124(Pt 2)198-206(2011 Jan)
Liu J,Xu J,Gu S,Nicholson BJ,Jiang JX

Developmental regulation of the direct interaction between the intracellular loop of connexin 45.6 and the C terminus of major intrinsic protein (aquaporin-0).
The Journal of biological chemistry280(23)22081-90(2005 Jun)
Yu XS,Yin X,Lafer EM,Jiang JX

Interaction of major intrinsic protein (aquaporin-0) with fiber connexins in lens development.
Journal of cell science117(Pt 6)871-80(2004 Feb)
Yu XS,Jiang JX

Partial amino acid sequence of the major intrinsic protein (MIP) of the chicken lens deduced from the nucleotide sequence of a cDNA clone.
Experimental eye research50(6)737-41(1990 Jun)
Kodama R,Agata K,Mochii M,Eguchi G