ugt2a4 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	ugt2a4
Entrez Gene ID	791613
Full Name	UDP glucuronosyltransferase 2 family, polypeptide A4
Synonyms	si:dkey-204e18.2
General protein information	Preferred Names UDP glucuronosyltransferase 2 family, polypeptide A4 Names UDP glucuronosyltransferase 2 family, polypeptide A4
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001177333.2	NP_001170804.2	UDP glucuronosyltransferase 2 family, polypeptide A4 precursor

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007029	XP_308743.3
Danio rerio (zebrafish)	ugt2a6	NP_001138283.1
Danio rerio (zebrafish)	ugt2a4	NP_001170804.2
Drosophila melanogaster (fruit fly)	Ugt35a	NP_524314.2
Drosophila melanogaster (fruit fly)	Ugt86Dg	NP_652622.3
Xenopus tropicalis (tropical clawed frog)	ugt2a1	XP_002936510.2
Gallus gallus (chicken)	UGT2A3	XP_004941249.1
Danio rerio (zebrafish)	ugt2a2	NP_001018306.2
Drosophila melanogaster (fruit fly)	Ugt86Dd	NP_001097744.1
Drosophila melanogaster (fruit fly)	CG31002	NP_651866.1
Homo sapiens (human)	UGT2A3	NP_079019.3
Pan troglodytes (chimpanzee)	UGT2A3	XP_526602.2
Danio rerio (zebrafish)	ugt2b1	NP_001170809.1
Danio rerio (zebrafish)	ugt2b3	NP_001170812.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006222	XP_316292.4
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006223	XP_001688832.1
Bos taurus (cattle)	UGT2A3	NP_001092414.1
Danio rerio (zebrafish)	zgc:172315	NP_001107098.1
Canis lupus familiaris (dog)	LOC100856129	XP_003639510.2
Danio rerio (zebrafish)	LOC100002369	XP_005162516.1
Danio rerio (zebrafish)	ugt2a1	NP_001177979.1
Danio rerio (zebrafish)	LOC100148803	XP_001919053.1
Danio rerio (zebrafish)	ugt2a3	NP_001170814.2
Mus musculus (house mouse)	Ugt2a3	NP_082370.2
Rattus norvegicus (Norway rat)	Ugt2a3	NP_001129341.1
Danio rerio (zebrafish)	ugt2a5	NP_001070111.2
Danio rerio (zebrafish)	LOC571561	XP_005162515.1
Danio rerio (zebrafish)	ugt2b6	NP_001170806.1
Macaca mulatta (Rhesus monkey)	UGT2A3	XP_001107830.1
Canis lupus familiaris (dog)	UGT2A1	XP_005628323.1
Drosophila melanogaster (fruit fly)	Ugt35b	NP_524313.2
Drosophila melanogaster (fruit fly)	Ugt86De	NP_652623.2

Gene Ontology
Bibliography

Related articles in PubMed

Toxic effects of triclosan on a zebrafish (Danio rerio) liver cell line, ZFL.
Zhou Z, Yang J, Chan KM
Aquatic toxicology (Amsterdam, Netherlands)191175-188(2017 Oct)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Characterization of the zebrafish Ugt repertoire reveals a new class of drug-metabolizing UDP glucuronosyltransferases.
Wang Y, Huang H, Wu Q
Molecular pharmacology86(1)62-75(2014 Jul)

Cloning and comparative analyses of the zebrafish Ugt repertoire reveal its evolutionary diversity.
Huang H, Wu Q
PloS one5(2)e9144(2010 Feb)

Adaptive evolution of multiple-variable exons and structural diversity of drug-metabolizing enzymes.
Li C, Wu Q
BMC evolutionary biology769(2007 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ugt2a4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ugt2a4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa30859	NM_001177333.2 Latest version!	Danio rerio UDP glucuronosyltransferase 2 family, polypeptide A4 (ugt2a4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ugt2a4 ( NM_001177333.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001170804.2 Danio rerio UDP glucuronosyltransferase 2 family, polypeptide A4 (ugt2a4), mRNA.

Price & Availability↑

CloneID	ODa30859
Clone ID Related Accession (Same CDS sequence)	NM_001177333.2
Accession Version	NM_001177333.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1602bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1542902400000
Organism	Danio rerio(zebrafish)
Product	UDP glucuronosyltransferase 2 family, polypeptide A4 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CU571335.5. On Jul 17, 2010 this sequence version replaced NM_001177333.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: GU299129.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168447, SAMEA2168448 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACTTCAG GGGCTTTATT AGTGTGTCTG CTGCTGTGTG GAGTAGATGT CGGCTGGTCT 
GGCAGGGTTT TGGTGATGCC AGGCGAGTAC AGTCACTGGC ACAACATGCG GGCGATCATT 
GAAGCTCTGG TCGATCGCAA CCACAGTGTG ACGGTGTTAG TCAGCTCTTC ATCTCCTACA 
GTACCGCACA CACAGAAGGC GCGCTTTGAT TACCACGTCT TCAAAGTCAA CATGGACAAA 
GAAGAGGCCA AGGTCATATG GAGTGACTTT ACTCATCTCT GGATGAAAGA GACCGACAGC 
AAATTGGAGA GAGGTTTCCT GATATGGCGA GTGATGTCCA ACTTTAGGAG ACTTGCTGCT 
GATGTGTGCC GGAGCCTTCT TCAAAACGAT GATCTCCTAC AAATGCTTGG GGAATCTCAT 
TACGACGTGC TTTTTTCTGA TCCCATGATG CCGTGTTCTG ACCTGATGGC GCAGACGCTG 
AACATCCCGC AAGTCATCTC TCTTCGGTTA ACTTTCGCGT ATACTTTTGA GAGGATGTGT 
GGTCAGATGC CCGCTCCTCC GTCTTATGTT CCTGCAGTGG CTCTGACAGA TCACCTCACC 
GACCGCATGA GCTTCATGGA GAGAGTTGAA AACATGCTGC TCTACTTCAT ACATACTACT 
GTGTTTCGCC TGAACACAAT GCTTACGGTT GATCGGCTGT ACACTGAAAT ACGTGGTAAA 
CCCACAACTA TGTGTGAGAC CATGGGAAAA GCAGATATCT GGCTGATAAG AACGTACTGG 
GATTTCGAGT ATCCGCGTCC ATTCCCACCT AACTTTAAGT TTGTTGGAGG ACTGCACTGC 
AAACCTGCCA AACCCCTGTC TAAGGAAATG GAGGAGTTTG TTCAGAGCTC TGGAGATCAC 
GGCGTCGTTG TTTTCTCATT GGGCTCCATG ATTAAAAACC TGACATCGGA AAGAGCCAAC 
ACTATTGCTG CTGCTCTGGG CCAGATCCCG CAAAAGGTTG TTTGGCGTTA CAGTGGGAAA 
ACTCCAGAAA CACTGGCTCC CAATACTAAA ATCTACGACT GGATCCCACA GAATGATTTG 
CTTGGTCATC CAAAAACGAA GGCTTTCATC ACTCATGGTG GCACAAATGG ACTGTATGAG 
GCTATTTATC ACGGTGTCCC GATGGTGGGT TTGCCACTGT TTGCTGATCA GCCTGATAAC 
CTACTGCACA TGAAAACCAA AGGAGCTGCT GTAGTCCTTG ATATCAACAC ACTGGAATCC 
AAAGACCTGG TGGATGCTCT AAAGACTGTC TTAAATAACC CATCGTACAA GGAGAGCATC 
ATGAGGCTGT CCAGAATCCA CCACGATCAG CCGATGAAGC CGCTGGATCA GGCCGTGTAC 
TGGATTGAGT TTGTGATGCG GAATAAAGGA GCCAAACATC TGCGAGTTCA GGCGCATGAG 
CTGAGCTGGT ATCAGTACCA CTGTCTGGAT GTCGCGGCCT TCTTACTCTC CATCGCCGCT 
CTGATCACAT TCCTCTGGGT TAAAGCATGC TGCTTCCTTT TCCGCAGATG TGTCAGGAAA 
ACCCGTCCTG AGAGGAAAAC ACAGAAGAGT AAAAATGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001170804.2
CDS	22..1623
Translation	MTSGALLVCLLLCGVDVGWSGRVLVMPGEYSHWHNMRAIIEALVDRNHSVTVLVSSSSPTVPHTQKARFDYHVFKVNMDKEEAKVIWSDFTHLWMKETDSKLERGFLIWRVMSNFRRLAADVCRSLLQNDDLLQMLGESHYDVLFSDPMMPCSDLMAQTLNIPQVISLRLTFAYTFERMCGQMPAPPSYVPAVALTDHLTDRMSFMERVENMLLYFIHTTVFRLNTMLTVDRLYTEIRGKPTTMCETMGKADIWLIRTYWDFEYPRPFPPNFKFVGGLHCKPAKPLSKEMEEFVQSSGDHGVVVFSLGSMIKNLTSERANTIAAALGQIPQKVVWRYSGKTPETLAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFADQPDNLLHMKTKGAAVVLDINTLESKDLVDALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVAAFLLSIAALITFLWVKACCFLFRRCVRKTRPERKTQKSKNE

Target ORF information:

RefSeq Version	NM_001177333.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio UDP glucuronosyltransferase 2 family, polypeptide A4 (ugt2a4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001177333.2

ORF Insert Sequence:

ATGACTTCAG GGGCTTTATT AGTGTGTCTG CTGCTGTGTG GAGTAGATGT CGGCTGGTCT 
GGCAGGGTTT TGGTGATGCC AGGCGAGTAC AGTCACTGGC ACAACATGCG GGCGATCATT 
GAAGCTCTGG TCGATCGCAA CCACAGTGTG ACGGTGTTAG TCAGCTCTTC ATCTCCTACA 
GTACCGCACA CACAGAAGGC GCGCTTTGAT TACCACGTCT TCAAAGTCAA CATGGACAAA 
GAAGAGGCCA AGGTCATATG GAGTGACTTT ACTCATCTCT GGATGAAAGA GACCGACAGC 
AAATTGGAGA GAGGTTTCCT GATATGGCGA GTGATGTCCA ACTTTAGGAG ACTTGCTGCT 
GATGTGTGCC GGAGCCTTCT TCAAAACGAT GATCTCCTAC AAATGCTTGG GGAATCTCAT 
TACGACGTGC TTTTTTCTGA TCCCATGATG CCGTGTTCTG ACCTGATGGC GCAGACGCTG 
AACATCCCGC AAGTCATCTC TCTTCGGTTA ACTTTCGCGT ATACTTTTGA GAGGATGTGT 
GGTCAGATGC CCGCTCCTCC GTCTTATGTT CCTGCAGTGG CTCTGACAGA TCACCTCACC 
GACCGCATGA GCTTCATGGA GAGAGTTGAA AACATGCTGC TCTACTTCAT ACATACTACT 
GTGTTTCGCC TGAACACAAT GCTTACGGTT GATCGGCTGT ACACTGAAAT ACGTGGTAAA 
CCCACAACTA TGTGTGAGAC CATGGGAAAA GCAGATATCT GGCTGATAAG AACGTACTGG 
GATTTCGAGT ATCCGCGTCC ATTCCCACCT AACTTTAAGT TTGTTGGAGG ACTGCACTGC 
AAACCTGCCA AACCCCTGTC TAAGGAAATG GAGGAGTTTG TTCAGAGCTC TGGAGATCAC 
GGCGTCGTTG TTTTCTCATT GGGCTCCATG ATTAAAAACC TGACATCGGA AAGAGCCAAC 
ACTATTGCTG CTGCTCTGGG CCAGATCCCG CAAAAGGTTG TTTGGCGTTA CAGTGGGAAA 
ACTCCAGAAA CACTGGCTCC CAATACTAAA ATCTACGACT GGATCCCACA GAATGATTTG 
CTTGGTCATC CAAAAACGAA GGCTTTCATC ACTCATGGTG GCACAAATGG ACTGTATGAG 
GCTATTTATC ACGGTGTCCC GATGGTGGGT TTGCCACTGT TTGCTGATCA GCCTGATAAC 
CTACTGCACA TGAAAACCAA AGGAGCTGCT GTAGTCCTTG ATATCAACAC ACTGGAATCC 
AAAGACCTGG TGGATGCTCT AAAGACTGTC TTAAATAACC CATCGTACAA GGAGAGCATC 
ATGAGGCTGT CCAGAATCCA CCACGATCAG CCGATGAAGC CGCTGGATCA GGCCGTGTAC 
TGGATTGAGT TTGTGATGCG GAATAAAGGA GCCAAACATC TGCGAGTTCA GGCGCATGAG 
CTGAGCTGGT ATCAGTACCA CTGTCTGGAT GTCGCGGCCT TCTTACTCTC CATCGCCGCT 
CTGATCACAT TCCTCTGGGT TAAAGCATGC TGCTTCCTTT TCCGCAGATG TGTCAGGAAA 
ACCCGTCCTG AGAGGAAAAC ACAGAAGAGT AAAAATGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Toxic effects of triclosan on a zebrafish (Danio rerio) liver cell line, ZFL.
Aquatic toxicology (Amsterdam, Netherlands)191175-188(2017 Oct)
Zhou Z,Yang J,Chan KM

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Characterization of the zebrafish Ugt repertoire reveals a new class of drug-metabolizing UDP glucuronosyltransferases.
Molecular pharmacology86(1)62-75(2014 Jul)
Wang Y,Huang H,Wu Q

Cloning and comparative analyses of the zebrafish Ugt repertoire reveal its evolutionary diversity.
PloS one5(2)e9144(2010 Feb)
Huang H,Wu Q

Adaptive evolution of multiple-variable exons and structural diversity of drug-metabolizing enzymes.
BMC evolutionary biology769(2007 May)
Li C,Wu Q