gabbr2 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	gabbr2
Entrez Gene ID	560267
Full Name	gamma-aminobutyric acid (GABA) B receptor, 2
Synonyms	si:dkey-190l1.2
General protein information	Preferred Names gamma-aminobutyric acid (GABA) B receptor, 2 Names gamma-aminobutyric acid type B receptor subunit 2
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001144043.1	NP_001137515.1	gamma-aminobutyric acid type B receptor subunit 2 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	GABBR2	NP_005449.5
Drosophila melanogaster (fruit fly)	GABA-B-R2	NP_732658.1
Xenopus tropicalis (tropical clawed frog)	gabbr2	NP_001016007.2
Anopheles gambiae (African malaria mosquito)	GPRGBB2	XP_557488.3
Canis lupus familiaris (dog)	GABBR2	XP_538749.2
Mus musculus (house mouse)	Gabbr2	NP_001074610.1
Rattus norvegicus (Norway rat)	Gabbr2	NP_113990.1
Caenorhabditis elegans (roundworm)	gbb-2	NP_500579.3
Pan troglodytes (chimpanzee)	GABBR2	XP_520146.2
Bos taurus (cattle)	GABBR2	XP_002689780.1
Gallus gallus (chicken)	GABBR2	XP_419066.3
Danio rerio (zebrafish)	gabbr2	NP_001137515.1

Gene Ontology
Bibliography

Related articles in PubMed

γ-Aminobutyric acid receptor alpha 1 subunit loss of function causes genetic generalized epilepsy by impairing inhibitory network neurodevelopment.
Samarut É, Swaminathan A, Riché R, Liao M, Hassan-Abdi R, Renault S, Allard M, Dufour L, Cossette P, Soussi-Yanicostas N, Drapeau P
Epilepsia59(11)2061-2074(2018 11)

Semicarbazide disturbs the reproductive system of male zebrafish (Danio rerio) through the GABAergic system.
Yu M, Feng Y, Zhang X, Wang J, Tian H, Wang W, Ru S
Reproductive toxicology (Elmsford, N.Y.)73149-157(2017 10)

Evolution of complexity in the zebrafish synapse proteome.
Bayés À, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 03)

Characterization of the γ-aminobutyric acid signaling system in the zebrafish (Danio rerio Hamilton) central nervous system by reverse transcription-quantitative polymerase chain reaction.
Cocco A, Rönnberg AM, Jin Z, André GI, Vossen LE, Bhandage AK, Thörnqvist PO, Birnir B, Winberg S
Neuroscience343300-321(2017 02)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following gabbr2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the gabbr2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa35848	NM_001144043.1 Latest version!	Danio rerio gamma-aminobutyric acid (GABA) B receptor, 2 (gabbr2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

gabbr2 ( NM_001144043.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001137515.1 Danio rerio gamma-aminobutyric acid (GABA) B receptor, 2 (gabbr2), mRNA.

Price & Availability↑

CloneID	ODa35848
Clone ID Related Accession (Same CDS sequence)	NM_001144043.1
Accession Version	NM_001144043.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2808bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1548432000000
Organism	Danio rerio(zebrafish)
Product	gamma-aminobutyric acid type B receptor subunit 2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BX649545.14, BX640579.10, BX927195.18, BX649369.6 and BX927389.19. On Jan 23, 2009 this sequence version replaced XM_683663.3. ##Evidence-Data-START## Transcript exon combination :: GFIL01011095.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168447, SAMEA4476730 [ECO:0000348] ##Evidence-Data-END##

ATGGCTCCGT CCCGGAGGGA CTGCAGATGT GACATGATCT TTCTGTCGGG ATGCCTACTC 
TTGTCCGTCT TGGGATTTCA ACCTGCATTG GCGAAGGTTT GCAACGATTA CACAAGGCAC 
GGCCTGGACA ACAACTGGTA CGCGAGGGAT GGTGAGAAGT TGCCTATCAT GGTCCTGATG 
CCGATGAATG AATCAGCGCT GATGAGCAGC ATCAGTCAGG GCATCGAACC GGCCGTTCAG 
CTGGCCATTC AGCACATCCG CGAGTCCAGG CAGTACTCCT TCTCACTCAT CACCAAAATC 
TACGACACAG AGTGTGACAA TGCAAAGGGA TTGCGGGCCT TCTTTGATGC AATCTGCTAC 
GGTCCGAAAC ATTTGATGAT CTTTGGAGGA GTGTGTCCAT CAGTGACTTC AATCATCGCT 
GAATCGTTGG AAGGGTGGAA CCTCGTGCAG CTTTCTTTTG CGGCCACTAC TCCTGTACTG 
GCAGACAGAA AAAAGTATCC AAATTTCTTC AGGACGGTCC CCTCAGACAA CGCTGTGAAT 
CCTGCTGTGG TGAAGTTTCT CAATTTTTAC AACTGGAGCC GGGTGGGAAC CCTGACACAG 
GACGTCCAAC GCTTTTCCGA GGTGCGAAAT GATTTGACCA ATGAGCTGGA GAAGGCAGAC 
ATCCAGATTG CAGACACAGA GAGTTTCTCT AACGATCCCT GTGTGAATGT GAAGAAACTG 
AAGGATAATG ACGTTCGAAT CATCATCGGT CAGTTTGATG AGAATCTGGC TGCTAAAGTC 
TTCTGCTGTG CCTACAACCT TAACATGTAT GGCAGCAAGT ACCAGTGGAT CATCCCGGGA 
TGGTACCAGG GGAACTGGTG GGAGCAGGCC AACTCTACAA ACTGCACCAC GAGGAAGCTG 
CTGACAGCCA TGGAGGGCTA CATCAGTGTG GACTTCGAGC CCCTCAGTGC CAAACAGATT 
AAGGGAATAT CAGGAAGAAC GCCGCAGGAG TATGAGAGGG AGTACAATCG AGAGCGAGAT 
CAAAAGGGAG TCGAGACCAG CAAATTCCAC GGCTTTGCAT ATGATGGCAT CTGGGTGATC 
GCTAAAACAC TCACGCGTGT CATGGAGCTC CTGAGACACA AGGAGAGGCA CGACATGTAC 
CACAACTTCA CAGTGGACGA CCGAGAGGTG GGAAAGATGG TCCTCGATGT GATGAATGAA 
ACCAACTTCT TTGGAGTGAC GGGTCAGGTG ATGTTCAGGA ATGGGGAACG CATGGGAACC 
ATAAAATTCA CCCAGTTTCA AGAGGGTCAG GAGGTGAAGG TGGGCGAGTA CAACGCCATT 
GCGGATGTAC TGGACCTTAT CAACAACACC ATCAGGTTTC AAGGTGTCGA ACCGCCGAAG 
GATCGGACAT TTGTGCGTCT GCAGCGTCGG CAAATTAACG TCCCGCTCTA CAGCATCTTG 
TCTACCATCA CGATCCTGGG CATGCTGATG GGTGGCGCTT TTCTCTTCTT CAACATCAAA 
AACCGCAACC ACAGGCTGAT CAAAATGTCG AGTCCCTATA TGAACAACCT GATCATTCTG 
GGTGGCATGC TGTCCTACGC CTCCATCTTC CTCTTCGGGC TGGACGGATC TTTTGTGTCA 
GACAAGGAGT TTGAAACCCT CTGCACTGTC CGTACATGGA TCCTCATTGT GGGGTACACA 
ACAGCGTTTG GTGCCATGTT TGCGAAGACC TGGAGAGTCC ATGCCATCTT CAAGAATGTA 
AAGATGAAGA AGAAGATTAT CAAGGACCAG AAGCTCTTTA TCATCGTGGG AGGGATGTTG 
CTGATTGATT TGTGCATCCT CATATGCTGG CAGATCGTGG ATCCCCTGAA GAGAACTGTG 
GAAGAGTACA GCTTGGAGGC GGATCCTCAG GGACGAGACA TCGCAATCCG GCCTTTCCTG 
GAGCACTGCG AGAACACACA CATGACCATT TGGCTGGGAA TTGTCTATGC CTACAAAGGC 
CTCCTTATGT TGTTCGGATG TTTCTTGGCC TGGGAGACGA GAAACGTGAG CATCCCAGCA 
CTGAACGACA GCAAGTACAT CGGTATGAGT GTGTACAATG TGGGCATCAT GTGCATCATC 
GGGGCAGCGG TGTCCTTCCT GACTCGGGAT CAGCCTAATG TTCAGTTCTG CATTGTGGCC 
CTGGTCATCA TTTTCTGCAG CACCATCACG CTGTGTCTGG TATTTGTGCC AAAATTTGTT 
ACAATGCGAA CAAACCCGGA TGCTGCTACA CAAAACCGGA GGTTGAAGTT CACCCAGAAC 
CAGAAGAAGG AAGATTCCAA GACATCCACC TCAGTGACCA GTGTTAACCA AGCCAACACT 
TCACGTCTGG ATGGACTACA GTCAGACAAT CATCGCCTTC GAATGAAAAT TACAGAGCTG 
GATAAAGAAC TGGAAGAGGT TACCATGCAA CTCCAGGACA CTCCAGAAAA GACTCCATAC 
ATTAAACAAA ACCACTACCA AGATGCCAAC AATATCCTGA GCATACGCAA CTTCACTGAC 
GGCAAAGATG GAGAGAAGTC TCTGAAGAAC CACCTAGAGC AGAAACCCCA GGCTCAGTGG 
GGATCCGCGG ATCCTTCTAG GATAAGTAGA GGTCCACTAG AAGACATCAA CTCACCAGAA 
CACATACAGC GCCGGCTATC CTTGCAGCTG CCAATCCTGC ATCATGCCTA TCTACCCTCC 
ATAGGAGGTG TGGACGCAAG TTGCAGCAGT CCCACAAGCA GCCCATCCTC CAGTCCCCGC 
CACAGACACA TGCCTCCCTC CTACAGGGTC ATGGTGTCCG GCCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001137515.1
CDS	1..2808
Translation	MAPSRRDCRCDMIFLSGCLLLSVLGFQPALAKVCNDYTRHGLDNNWYARDGEKLPIMVLMPMNESALMSSISQGIEPAVQLAIQHIRESRQYSFSLITKIYDTECDNAKGLRAFFDAICYGPKHLMIFGGVCPSVTSIIAESLEGWNLVQLSFAATTPVLADRKKYPNFFRTVPSDNAVNPAVVKFLNFYNWSRVGTLTQDVQRFSEVRNDLTNELEKADIQIADTESFSNDPCVNVKKLKDNDVRIIIGQFDENLAAKVFCCAYNLNMYGSKYQWIIPGWYQGNWWEQANSTNCTTRKLLTAMEGYISVDFEPLSAKQIKGISGRTPQEYEREYNRERDQKGVETSKFHGFAYDGIWVIAKTLTRVMELLRHKERHDMYHNFTVDDREVGKMVLDVMNETNFFGVTGQVMFRNGERMGTIKFTQFQEGQEVKVGEYNAIADVLDLINNTIRFQGVEPPKDRTFVRLQRRQINVPLYSILSTITILGMLMGGAFLFFNIKNRNHRLIKMSSPYMNNLIILGGMLSYASIFLFGLDGSFVSDKEFETLCTVRTWILIVGYTTAFGAMFAKTWRVHAIFKNVKMKKKIIKDQKLFIIVGGMLLIDLCILICWQIVDPLKRTVEEYSLEADPQGRDIAIRPFLEHCENTHMTIWLGIVYAYKGLLMLFGCFLAWETRNVSIPALNDSKYIGMSVYNVGIMCIIGAAVSFLTRDQPNVQFCIVALVIIFCSTITLCLVFVPKFVTMRTNPDAATQNRRLKFTQNQKKEDSKTSTSVTSVNQANTSRLDGLQSDNHRLRMKITELDKELEEVTMQLQDTPEKTPYIKQNHYQDANNILSIRNFTDGKDGEKSLKNHLEQKPQAQWGSADPSRISRGPLEDINSPEHIQRRLSLQLPILHHAYLPSIGGVDASCSSPTSSPSSSPRHRHMPPSYRVMVSGL

Target ORF information:

RefSeq Version	NM_001144043.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio gamma-aminobutyric acid (GABA) B receptor, 2 (gabbr2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001144043.1

ORF Insert Sequence:

ATGGCTCCGT CCCGGAGGGA CTGCAGATGT GACATGATCT TTCTGTCGGG ATGCCTACTC 
TTGTCCGTCT TGGGATTTCA ACCTGCATTG GCGAAGGTTT GCAACGATTA CACAAGGCAC 
GGCCTGGACA ACAACTGGTA CGCGAGGGAT GGTGAGAAGT TGCCTATCAT GGTCCTGATG 
CCGATGAATG AATCAGCGCT GATGAGCAGC ATCAGTCAGG GCATCGAACC GGCCGTTCAG 
CTGGCCATTC AGCACATCCG CGAGTCCAGG CAGTACTCCT TCTCACTCAT CACCAAAATC 
TACGACACAG AGTGTGACAA TGCAAAGGGA TTGCGGGCCT TCTTTGATGC AATCTGCTAC 
GGTCCGAAAC ATTTGATGAT CTTTGGAGGA GTGTGTCCAT CAGTGACTTC AATCATCGCT 
GAATCGTTGG AAGGGTGGAA CCTCGTGCAG CTTTCTTTTG CGGCCACTAC TCCTGTACTG 
GCAGACAGAA AAAAGTATCC AAATTTCTTC AGGACGGTCC CCTCAGACAA CGCTGTGAAT 
CCTGCTGTGG TGAAGTTTCT CAATTTTTAC AACTGGAGCC GGGTGGGAAC CCTGACACAG 
GACGTCCAAC GCTTTTCCGA GGTGCGAAAT GATTTGACCA ATGAGCTGGA GAAGGCAGAC 
ATCCAGATTG CAGACACAGA GAGTTTCTCT AACGATCCCT GTGTGAATGT GAAGAAACTG 
AAGGATAATG ACGTTCGAAT CATCATCGGT CAGTTTGATG AGAATCTGGC TGCTAAAGTC 
TTCTGCTGTG CCTACAACCT TAACATGTAT GGCAGCAAGT ACCAGTGGAT CATCCCGGGA 
TGGTACCAGG GGAACTGGTG GGAGCAGGCC AACTCTACAA ACTGCACCAC GAGGAAGCTG 
CTGACAGCCA TGGAGGGCTA CATCAGTGTG GACTTCGAGC CCCTCAGTGC CAAACAGATT 
AAGGGAATAT CAGGAAGAAC GCCGCAGGAG TATGAGAGGG AGTACAATCG AGAGCGAGAT 
CAAAAGGGAG TCGAGACCAG CAAATTCCAC GGCTTTGCAT ATGATGGCAT CTGGGTGATC 
GCTAAAACAC TCACGCGTGT CATGGAGCTC CTGAGACACA AGGAGAGGCA CGACATGTAC 
CACAACTTCA CAGTGGACGA CCGAGAGGTG GGAAAGATGG TCCTCGATGT GATGAATGAA 
ACCAACTTCT TTGGAGTGAC GGGTCAGGTG ATGTTCAGGA ATGGGGAACG CATGGGAACC 
ATAAAATTCA CCCAGTTTCA AGAGGGTCAG GAGGTGAAGG TGGGCGAGTA CAACGCCATT 
GCGGATGTAC TGGACCTTAT CAACAACACC ATCAGGTTTC AAGGTGTCGA ACCGCCGAAG 
GATCGGACAT TTGTGCGTCT GCAGCGTCGG CAAATTAACG TCCCGCTCTA CAGCATCTTG 
TCTACCATCA CGATCCTGGG CATGCTGATG GGTGGCGCTT TTCTCTTCTT CAACATCAAA 
AACCGCAACC ACAGGCTGAT CAAAATGTCG AGTCCCTATA TGAACAACCT GATCATTCTG 
GGTGGCATGC TGTCCTACGC CTCCATCTTC CTCTTCGGGC TGGACGGATC TTTTGTGTCA 
GACAAGGAGT TTGAAACCCT CTGCACTGTC CGTACATGGA TCCTCATTGT GGGGTACACA 
ACAGCGTTTG GTGCCATGTT TGCGAAGACC TGGAGAGTCC ATGCCATCTT CAAGAATGTA 
AAGATGAAGA AGAAGATTAT CAAGGACCAG AAGCTCTTTA TCATCGTGGG AGGGATGTTG 
CTGATTGATT TGTGCATCCT CATATGCTGG CAGATCGTGG ATCCCCTGAA GAGAACTGTG 
GAAGAGTACA GCTTGGAGGC GGATCCTCAG GGACGAGACA TCGCAATCCG GCCTTTCCTG 
GAGCACTGCG AGAACACACA CATGACCATT TGGCTGGGAA TTGTCTATGC CTACAAAGGC 
CTCCTTATGT TGTTCGGATG TTTCTTGGCC TGGGAGACGA GAAACGTGAG CATCCCAGCA 
CTGAACGACA GCAAGTACAT CGGTATGAGT GTGTACAATG TGGGCATCAT GTGCATCATC 
GGGGCAGCGG TGTCCTTCCT GACTCGGGAT CAGCCTAATG TTCAGTTCTG CATTGTGGCC 
CTGGTCATCA TTTTCTGCAG CACCATCACG CTGTGTCTGG TATTTGTGCC AAAATTTGTT 
ACAATGCGAA CAAACCCGGA TGCTGCTACA CAAAACCGGA GGTTGAAGTT CACCCAGAAC 
CAGAAGAAGG AAGATTCCAA GACATCCACC TCAGTGACCA GTGTTAACCA AGCCAACACT 
TCACGTCTGG ATGGACTACA GTCAGACAAT CATCGCCTTC GAATGAAAAT TACAGAGCTG 
GATAAAGAAC TGGAAGAGGT TACCATGCAA CTCCAGGACA CTCCAGAAAA GACTCCATAC 
ATTAAACAAA ACCACTACCA AGATGCCAAC AATATCCTGA GCATACGCAA CTTCACTGAC 
GGCAAAGATG GAGAGAAGTC TCTGAAGAAC CACCTAGAGC AGAAACCCCA GGCTCAGTGG 
GGATCCGCGG ATCCTTCTAG GATAAGTAGA GGTCCACTAG AAGACATCAA CTCACCAGAA 
CACATACAGC GCCGGCTATC CTTGCAGCTG CCAATCCTGC ATCATGCCTA TCTACCCTCC 
ATAGGAGGTG TGGACGCAAG TTGCAGCAGT CCCACAAGCA GCCCATCCTC CAGTCCCCGC 
CACAGACACA TGCCTCCCTC CTACAGGGTC ATGGTGTCCG GCCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

γ-Aminobutyric acid receptor alpha 1 subunit loss of function causes genetic generalized epilepsy by impairing inhibitory network neurodevelopment.
Epilepsia59(11)2061-2074(2018 11)
Samarut É,Swaminathan A,Riché R,Liao M,Hassan-Abdi R,Renault S,Allard M,Dufour L,Cossette P,Soussi-Yanicostas N,Drapeau P

Semicarbazide disturbs the reproductive system of male zebrafish (Danio rerio) through the GABAergic system.
Reproductive toxicology (Elmsford, N.Y.)73149-157(2017 10)
Yu M,Feng Y,Zhang X,Wang J,Tian H,Wang W,Ru S

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 03)
Bayés À,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

Characterization of the γ-aminobutyric acid signaling system in the zebrafish (Danio rerio Hamilton) central nervous system by reverse transcription-quantitative polymerase chain reaction.
Neuroscience343300-321(2017 02)
Cocco A,Rönnberg AM,Jin Z,André GI,Vossen LE,Bhandage AK,Thörnqvist PO,Birnir B,Winberg S

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

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gabbr2 cDNA ORF clone, Danio rerio(zebrafish)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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