casp9 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	casp9
Entrez Gene ID	492763
Full Name	caspase 9, apoptosis-related cysteine peptidase
Synonyms	im:7136887,zgc:101776
General protein information	Preferred Names caspase 9, apoptosis-related cysteine peptidase Names caspase-9 caspase 9, apoptosis-related cysteine protease
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001007404.2	NP_001007405.2	caspase-9

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	CASP9	XP_001082859.1
Mus musculus (house mouse)	Casp9	NP_056548.2
Rattus norvegicus (Norway rat)	Casp9	NP_113820.1
Canis lupus familiaris (dog)	CASP9	NP_001026803.1
Danio rerio (zebrafish)	casp9	NP_001007405.2
Bos taurus (cattle)	CASP9	NP_001192433.1
Homo sapiens (human)	CASP9	NP_001220.2
Pan troglodytes (chimpanzee)	CASP9	XP_513049.2
Gallus gallus (chicken)	CASP9	XP_424580.4

Gene Ontology
Bibliography

Related articles in PubMed

Mechanism of isoniazid-induced hepatotoxicity in zebrafish larvae: Activation of ROS-mediated ERS, apoptosis and the Nrf2 pathway.
Jia ZL, Cen J, Wang JB, Zhang F, Xia Q, Wang X, Chen XQ, Wang RC, Hsiao CD, Liu KC, Zhang Y
Chemosphere227541-550(2019 Jul)

Hepatotoxicity Induced by Isoniazid-Lipopolysaccharide through Endoplasmic Reticulum Stress, Autophagy, and Apoptosis Pathways in Zebrafish.
Zhang Y, Cen J, Jia Z, Hsiao CD, Xia Q, Wang X, Chen X, Wang R, Jiang Z, Zhang L, Liu K
Antimicrobial agents and chemotherapy63(5)(2019 05)

Isoliquiritigenin as an antioxidant phytochemical ameliorates the developmental anomalies of zebrafish induced by 2,2',4,4'-tetrabromodiphenyl ether.
Wang C, Yang L, Hu Y, Zhu J, Xia R, Yu Y, Shen J, Zhang Z, Wang SL
The Science of the total environment666390-398(2019 May)

Optimization of the Gal4/UAS transgenic tools in zebrafish.
Zhang Y, Ouyang J, Qie J, Zhang G, Liu L, Yang P
Applied microbiology and biotechnology103(4)1789-1799(2019 Feb)

Psoralen Induces Developmental Toxicity in Zebrafish Embryos/Larvae Through Oxidative Stress, Apoptosis, and Energy Metabolism Disorder.
Xia Q, Wei L, Zhang Y, Kong H, Shi Y, Wang X, Chen X, Han L, Liu K
Frontiers in pharmacology91457(2018)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following casp9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the casp9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa04035	NM_001007404.2 Latest version!	Danio rerio caspase 9, apoptosis-related cysteine peptidase (casp9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

casp9 ( NM_001007404.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001007405.2 Danio rerio caspase 9, apoptosis-related cysteine peptidase (casp9), mRNA.

Price & Availability↑

CloneID	ODa04035
Clone ID Related Accession (Same CDS sequence)	NM_001007404.2
Accession Version	NM_001007404.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1311bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1576771200000
Organism	Danio rerio(zebrafish)
Product	caspase-9
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH493348.1, EB967264.1, EH440298.1, EH466201.1 and CR376748.8. On Apr 11, 2009 this sequence version replaced NM_001007404.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: GFIL01003094.1, GDQH01015333.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGGAGCAGA AACACAGACA GATTCTTCAG CGGCACAGGT TAAACCTCGT CAAGGCATTG 
AATCCCGAAG ACGTCTGTGA TAAGCTTCTG TCAAAGGGGG TCTTCACTCA GGACATGATC 
GATGAAATAC AGAGCAAGGC AACCAGACGT GACCAAGCCA GGCAACTGGT GAAAGACCTG 
GAGACGAGAG GAAGTCTTGC TTTCCCAGCC TTTCTTGATT CCCTGCGTGA GACTGGCCAC 
AATGATCTTG CAGAGCTCCT TCAAAGCGGA GATGGTGTTC ATCGCCCTCC TGTCATTTCT 
GTACAGCCTT CACCGATCCC TCTGCCAGTC CAAAATCTAA ATCATACTGA AAAGCCAGAC 
AAACCTGATA TCGCTTCTCC ACGATTAGTA CCACTGAGAC CTGAAAGCCT GCCGGTGCAC 
AAGACATATA GTCCACCTTC TGAAACTGTG GTGAGACCAA CCAGGCCAAG ACGTGACAGT 
ATACAGTGCT ACAAGATGGA TGCCAGTCCG TGTGGGGTCT GCTTGATCAT AAACAATATC 
AACTTTGAAA AAGCCTCTGA ACTAAATGAC CGCAAGGGCT CCAACATCGA CTGCGACAAG 
CTGGAGAAAA GATTTAAAGC GCTCAACTTT GAGGTTACAG TAAAAAGGAA CTTGAAATCT 
AAACGCATAA GGCACGAGAT GGCATCTTTA GCGAAGAAAG ATCACTCTAC ATACGACTGC 
TGTGTGGTCA TCATCCTTTC ACATGGCACT GAGGCAAGCC ATAATCGATT CCCTGGTGCA 
GTTCATGGTG TTGACGGACC GGCTGTCCCA ATTCAGATAA TCACAAACTA CCTCAATGGC 
CAGAACTGTC CTTCTCTTCA GGGCAAGCCC AAGTTATTTT TCATCCAGGC CTGCGGAGGA 
GGTGAGAAGG ATATTGGTTT TGAGGTTTCT CCAGATGACG TTCAACCATC TATAGGTGGG 
ATAGATGACG AGATGGACGC TATTCCCATG TCCTCTAGCA GTGACTCTCT CAGCACAGCG 
TCTGATGAAC TTGATGCACG GGCAAGTTTG CCCACGCCCA GTGACATCCT GGTGTCCTAC 
TCAACATTTC CAGGTTATGT CTCCTGGAGG GACACAGAGG CCGGCTCTTG GTATGTGGAG 
AATCTTGATC GTGTGCTGGA GGAAAACGCT ATCACAGATG ATCTGGTGAC CATGCTGATG 
TTGGTAAATG ATGCAGTCTC ACAAATATCT GCCAAAGGCC TGTATAAACA AATGCCTGGG 
TCTTTCAACT TCCTCCGAAA ACTTCTCTAC TTTCAGTCTT CACAGTCATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001007405.2
CDS	216..1526
Translation	MEQKHRQILQRHRLNLVKALNPEDVCDKLLSKGVFTQDMIDEIQSKATRRDQARQLVKDLETRGSLAFPAFLDSLRETGHNDLAELLQSGDGVHRPPVISVQPSPIPLPVQNLNHTEKPDKPDIASPRLVPLRPESLPVHKTYSPPSETVVRPTRPRRDSIQCYKMDASPCGVCLIINNINFEKASELNDRKGSNIDCDKLEKRFKALNFEVTVKRNLKSKRIRHEMASLAKKDHSTYDCCVVIILSHGTEASHNRFPGAVHGVDGPAVPIQIITNYLNGQNCPSLQGKPKLFFIQACGGGEKDIGFEVSPDDVQPSIGGIDDEMDAIPMSSSSDSLSTASDELDARASLPTPSDILVSYSTFPGYVSWRDTEAGSWYVENLDRVLEENAITDDLVTMLMLVNDAVSQISAKGLYKQMPGSFNFLRKLLYFQSSQS

Target ORF information:

RefSeq Version	NM_001007404.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio caspase 9, apoptosis-related cysteine peptidase (casp9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001007404.2

ORF Insert Sequence:

ATGGAGCAGA AACACAGACA GATTCTTCAG CGGCACAGGT TAAACCTCGT CAAGGCATTG 
AATCCCGAAG ACGTCTGTGA TAAGCTTCTG TCAAAGGGGG TCTTCACTCA GGACATGATC 
GATGAAATAC AGAGCAAGGC AACCAGACGT GACCAAGCCA GGCAACTGGT GAAAGACCTG 
GAGACGAGAG GAAGTCTTGC TTTCCCAGCC TTTCTTGATT CCCTGCGTGA GACTGGCCAC 
AATGATCTTG CAGAGCTCCT TCAAAGCGGA GATGGTGTTC ATCGCCCTCC TGTCATTTCT 
GTACAGCCTT CACCGATCCC TCTGCCAGTC CAAAATCTAA ATCATACTGA AAAGCCAGAC 
AAACCTGATA TCGCTTCTCC ACGATTAGTA CCACTGAGAC CTGAAAGCCT GCCGGTGCAC 
AAGACATATA GTCCACCTTC TGAAACTGTG GTGAGACCAA CCAGGCCAAG ACGTGACAGT 
ATACAGTGCT ACAAGATGGA TGCCAGTCCG TGTGGGGTCT GCTTGATCAT AAACAATATC 
AACTTTGAAA AAGCCTCTGA ACTAAATGAC CGCAAGGGCT CCAACATCGA CTGCGACAAG 
CTGGAGAAAA GATTTAAAGC GCTCAACTTT GAGGTTACAG TAAAAAGGAA CTTGAAATCT 
AAACGCATAA GGCACGAGAT GGCATCTTTA GCGAAGAAAG ATCACTCTAC ATACGACTGC 
TGTGTGGTCA TCATCCTTTC ACATGGCACT GAGGCAAGCC ATAATCGATT CCCTGGTGCA 
GTTCATGGTG TTGACGGACC GGCTGTCCCA ATTCAGATAA TCACAAACTA CCTCAATGGC 
CAGAACTGTC CTTCTCTTCA GGGCAAGCCC AAGTTATTTT TCATCCAGGC CTGCGGAGGA 
GGTGAGAAGG ATATTGGTTT TGAGGTTTCT CCAGATGACG TTCAACCATC TATAGGTGGG 
ATAGATGACG AGATGGACGC TATTCCCATG TCCTCTAGCA GTGACTCTCT CAGCACAGCG 
TCTGATGAAC TTGATGCACG GGCAAGTTTG CCCACGCCCA GTGACATCCT GGTGTCCTAC 
TCAACATTTC CAGGTTATGT CTCCTGGAGG GACACAGAGG CCGGCTCTTG GTATGTGGAG 
AATCTTGATC GTGTGCTGGA GGAAAACGCT ATCACAGATG ATCTGGTGAC CATGCTGATG 
TTGGTAAATG ATGCAGTCTC ACAAATATCT GCCAAAGGCC TGTATAAACA AATGCCTGGG 
TCTTTCAACT TCCTCCGAAA ACTTCTCTAC TTTCAGTCTT CACAGTCATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mechanism of isoniazid-induced hepatotoxicity in zebrafish larvae: Activation of ROS-mediated ERS, apoptosis and the Nrf2 pathway.
Chemosphere227541-550(2019 Jul)
Jia ZL,Cen J,Wang JB,Zhang F,Xia Q,Wang X,Chen XQ,Wang RC,Hsiao CD,Liu KC,Zhang Y

Hepatotoxicity Induced by Isoniazid-Lipopolysaccharide through Endoplasmic Reticulum Stress, Autophagy, and Apoptosis Pathways in Zebrafish.
Antimicrobial agents and chemotherapy63(5)(2019 05)
Zhang Y,Cen J,Jia Z,Hsiao CD,Xia Q,Wang X,Chen X,Wang R,Jiang Z,Zhang L,Liu K

Isoliquiritigenin as an antioxidant phytochemical ameliorates the developmental anomalies of zebrafish induced by 2,2',4,4'-tetrabromodiphenyl ether.
The Science of the total environment666390-398(2019 May)
Wang C,Yang L,Hu Y,Zhu J,Xia R,Yu Y,Shen J,Zhang Z,Wang SL

Optimization of the Gal4/UAS transgenic tools in zebrafish.
Applied microbiology and biotechnology103(4)1789-1799(2019 Feb)
Zhang Y,Ouyang J,Qie J,Zhang G,Liu L,Yang P

Psoralen Induces Developmental Toxicity in Zebrafish Embryos/Larvae Through Oxidative Stress, Apoptosis, and Energy Metabolism Disorder.
Frontiers in pharmacology91457(2018)
Xia Q,Wei L,Zhang Y,Kong H,Shi Y,Wang X,Chen X,Han L,Liu K

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casp9 cDNA ORF clone, Danio rerio(zebrafish)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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