xrcc5 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	xrcc5
Entrez Gene ID	449848
Full Name	X-ray repair complementing defective repair in Chinese hamster cells 5
Synonyms	Ku80,im:7137560,si:ch211-239d11.4
General protein information	Preferred Names X-ray repair complementing defective repair in Chinese hamster cells 5 Names X-ray repair cross-complementing protein 5 DNA binding protein
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001017360.2	NP_001017360.2	X-ray repair cross-complementing protein 5

Pathways from BioSystems

Homologies

Neurospora crassa	NCU00077	XP_956387.2
Macaca mulatta (Rhesus monkey)	XRCC5	XP_001084586.2
Bos taurus (cattle)	LOC531945	NP_001095611.1
Danio rerio (zebrafish)	LOC100331090	XP_002665537.3
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009910	XP_319031.4
Canis lupus familiaris (dog)	XRCC5	XP_536061.4
Rattus norvegicus (Norway rat)	Xrcc5	NP_803154.1
Schizosaccharomyces pombe (fission yeast)	pku80	NP_596791.1
Magnaporthe oryzae (rice blast fungus)	MGG_10157	XP_003713796.1
Mus musculus (house mouse)	Xrcc5	NP_033559.2
Gallus gallus (chicken)	XRCC5	XP_422072.4
Homo sapiens (human)	XRCC5	NP_066964.1
Pan troglodytes (chimpanzee)	XRCC5	XP_001151873.2
Danio rerio (zebrafish)	xrcc5	NP_001017360.1
Arabidopsis thaliana (thale cress)	KU80	NP_564520.1
Xenopus tropicalis (tropical clawed frog)	xrcc5	XP_002942054.2

Gene Ontology
Bibliography

Related articles in PubMed

Cellular responses to ionizing radiation change quickly over time during early development in zebrafish.
Honjo Y, Ichinohe T
Cell biology international43(5)516-527(2019 May)

Knock-In Strategy for Editing Human and Zebrafish Mitochondrial DNA Using Mito-CRISPR/Cas9 System.
Bian WP, Chen YL, Luo JJ, Wang C, Xie SL, Pei DS
ACS synthetic biology8(4)621-632(2019 04)

Stress-Induced Transcriptional Changes and DNA Damage Associated with Bis(2-ethylhexyl) Adipate Exposure in Zebrafish (Danio rerio) Larvae.
Boran H, Terzi S
Bulletin of environmental contamination and toxicology99(3)308-314(2017 Sep)

Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development.
Thyme SB, Schier AF
Cell reports15(4)707-714(2016 Apr)

Direct regulation of p53 by miR-142a-3p mediates the survival of hematopoietic stem and progenitor cells in zebrafish.
Lu X, Wei Y, Liu F
Cell discovery115027(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following xrcc5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the xrcc5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa41298	NM_001017360.2 Latest version!	Danio rerio X-ray repair complementing defective repair in Chinese hamster cells 5 (xrcc5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

xrcc5 ( NM_001017360.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001017360.2 Danio rerio X-ray repair complementing defective repair in Chinese hamster cells 5 (xrcc5), mRNA.

Price & Availability↑

CloneID	ODa41298
Clone ID Related Accession (Same CDS sequence)	NM_001017360.2
Accession Version	NM_001017360.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2184bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1578067200000
Organism	Danio rerio(zebrafish)
Product	X-ray repair cross-complementing protein 5
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CR339053.18 and CR392344.9. On Jun 13, 2015 this sequence version replaced NM_001017360.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY877316.1, GDQH01005405.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGCGAG CAGCGAAGTC AGCGCTGGTG CTCTGCATGG ATGTGGGTTT CTCCATGAGC 
AACTCTGGAC CTGGACAGGA GCCGCCATTT GAACAGGCCA AGAAAGTCAT CCAGAAGTTT 
GTCCAGCGGC AGGTGTTTGC TGAGAATAAG GATGAGATTG GTTTGGTGCT GTTTGGTACT 
GATGGCACCA AGAATCCTCT GGCCAATGAC GGTCAGTATG AGAACATCAC GGTTCACCGA 
CACCTCATGA TCCCTGATTT TGAACTGCTG GAGGAGATTG AGAGAGAACT GCAACCTGGC 
GGTCAGCAGG CAGACTGGCT CGATGCTCTG GTGGTTTGCA TGGACCTTCT GCAGAATGAA 
ACCATGGGGA AGAAGTATGA TCGTCTGAAC ATCGCCTTGC TGACGGATCT GAACATCCAG 
ACTTCAGAAG ATCAGCTGGA TATTATCATT CAGAACCTGA AGAAAGCTGG AATCACCCTG 
CAGTTTTTTT TGCCGTTCCC TGTGGATGTT GAGGATGAAG CCGGAGGTGG AGGTGATGCA 
GCAGGACCCT CAGCGCCTCC GTCCCGTCCA GGAAAAGGCT TGAGTCGCCA ACAAACACAA 
GGCCTGGAGA TGGTCAAACA CATCATGAGC AGCCTGGAGG ACGAGGACGG CCTGGAGGAG 
GTCTACACAT TCAGTGACGC TCTGGAGAAA CTCTCCATCT TCAAGCGTAT TGAAAGGAGG 
CCGATGGCAT GGCCGTGTCA GCTCACCATC GGCAGCTCTC TGTCTATTCG CATTGTTGGA 
TATAAAGCTG TGACAGAGGA AAAGGTGAAA AAGTCTTGGA CGATTGTGGA CGCTCAGAGT 
CACCAGAGAG ATGACGTGAA GAGAGAGACA GTTTACTGTC TGAACGATGA TGATGAAACT 
GAGGTGCAGA AAGACGACAC AATACAAGGT TACCGTTATG GAAGTGACAT TGTGCCGTTT 
TCAAAGGTGG ACGAGGAGCA GATGAAATAT AAGCATGATG GGAAGTGTTT CTCTGTGCTT 
GGCTTCACTA AACAGGAGCT GATTCCTCGT CATCAGTTTA TGGGAAGCCA AGTTGTCAAA 
GTCTTTGCAC CCAGAGATGA TGAGCATGCA GCAGTTGCTC TGTCCTCTCT GATTCGTGCT 
CTTGATGGTC TAAAGATGGC AGCCATTGTA CGTTATGCTT ACGACCGCCG CAGCAATCCT 
CAAGTGGGCG CCGCGTTTCC CTGCATAAAG AAAAAATATG AATGTCTGCT GTACGTTCAG 
CTGCCGTATA TGGAGGATCT CCGTCAGTTC ACTTTCCCCA TGCTGGAAAA CAACAAGAAG 
TTTATGCCAT CAGGGTCTCA GTTGTCAGCC GTAGATGCGC TGATCGACTC CATGATGCTG 
ATGGAGAAGG ATGAGAATGG AGAAAGTGTG GAGATCTTCA AAGTCAACCA CATCCCAAAC 
CCACAGTTCC AGAGGCTCTT CCAGTGTTTG CATCACCGCG GTGTGAATCC TGATGATCCT 
CTGCCTCCCG TGGATCCGTG GCTCAAGCGG GTCCTGGAAA GACCGCAGGC CGTGTCCGCT 
CGCTGCCAGG CCCCTCTGCG GGACGTCAAG ACCAGCTTCC CTCTCAAAGT GGTGGTGAAA 
AAGAAAGAGC AGAAGACGAG CGCAGACGTG TTCGGCAGCA GTGCTGATGA ACCAGATGCC 
AAGAAAGTCA AAGTGAATGA AGAAACCGAG TTTAACCTGG CTGAGATTAC AGAGGGAAAC 
ATCACATCGG TTGGCAGCGT CAATCCAGCC AGAGATTTCT GCACACTGAT AAGACAGAAG 
ACGGTTTCTT TCGATCAAGC GTGCCAGCAG CTGACCCACA GGATTGAGCA GTTGCTGGGC 
AACAGGAGCA CTGAGTATTA CACCAAGAGC ATCGCCTGCA TCCAGGCCTT CAGGGATCAG 
TCTGTACTGA GCGGAAACGC AGAGCTGTTC AACAGTTACC TGCAGTCTCT GAAGAGGAGC 
ATTGCTGACC GCAGCCTTCA GGACTTCTGG AACCTGCTCG CTCAAGATGC TCTAACGCTG 
ATTAGCAAAG ATGAAGTGGA GGCAAGCACC ATCTCCAAAC AAGAAGCAAA TCAGTTCCTG 
TCATTTGAGC AGAAGCAGGA AGTTGAAGTA GCTCCAGCGC AGGACGACAC TGGAGATGTG 
GATGATCTGC TGGACATGAT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001017360.2
CDS	16..2199
Translation	MARAAKSALVLCMDVGFSMSNSGPGQEPPFEQAKKVIQKFVQRQVFAENKDEIGLVLFGTDGTKNPLANDGQYENITVHRHLMIPDFELLEEIERELQPGGQQADWLDALVVCMDLLQNETMGKKYDRLNIALLTDLNIQTSEDQLDIIIQNLKKAGITLQFFLPFPVDVEDEAGGGGDAAGPSAPPSRPGKGLSRQQTQGLEMVKHIMSSLEDEDGLEEVYTFSDALEKLSIFKRIERRPMAWPCQLTIGSSLSIRIVGYKAVTEEKVKKSWTIVDAQSHQRDDVKRETVYCLNDDDETEVQKDDTIQGYRYGSDIVPFSKVDEEQMKYKHDGKCFSVLGFTKQELIPRHQFMGSQVVKVFAPRDDEHAAVALSSLIRALDGLKMAAIVRYAYDRRSNPQVGAAFPCIKKKYECLLYVQLPYMEDLRQFTFPMLENNKKFMPSGSQLSAVDALIDSMMLMEKDENGESVEIFKVNHIPNPQFQRLFQCLHHRGVNPDDPLPPVDPWLKRVLERPQAVSARCQAPLRDVKTSFPLKVVVKKKEQKTSADVFGSSADEPDAKKVKVNEETEFNLAEITEGNITSVGSVNPARDFCTLIRQKTVSFDQACQQLTHRIEQLLGNRSTEYYTKSIACIQAFRDQSVLSGNAELFNSYLQSLKRSIADRSLQDFWNLLAQDALTLISKDEVEASTISKQEANQFLSFEQKQEVEVAPAQDDTGDVDDLLDMM

Target ORF information:

RefSeq Version	NM_001017360.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio X-ray repair complementing defective repair in Chinese hamster cells 5 (xrcc5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001017360.2

ORF Insert Sequence:

ATGGCGCGAG CAGCGAAGTC AGCGCTGGTG CTCTGCATGG ATGTGGGTTT CTCCATGAGC 
AACTCTGGAC CTGGACAGGA GCCGCCATTT GAACAGGCCA AGAAAGTCAT CCAGAAGTTT 
GTCCAGCGGC AGGTGTTTGC TGAGAATAAG GATGAGATTG GTTTGGTGCT GTTTGGTACT 
GATGGCACCA AGAATCCTCT GGCCAATGAC GGTCAGTATG AGAACATCAC GGTTCACCGA 
CACCTCATGA TCCCTGATTT TGAACTGCTG GAGGAGATTG AGAGAGAACT GCAACCTGGC 
GGTCAGCAGG CAGACTGGCT CGATGCTCTG GTGGTTTGCA TGGACCTTCT GCAGAATGAA 
ACCATGGGGA AGAAGTATGA TCGTCTGAAC ATCGCCTTGC TGACGGATCT GAACATCCAG 
ACTTCAGAAG ATCAGCTGGA TATTATCATT CAGAACCTGA AGAAAGCTGG AATCACCCTG 
CAGTTTTTTT TGCCGTTCCC TGTGGATGTT GAGGATGAAG CCGGAGGTGG AGGTGATGCA 
GCAGGACCCT CAGCGCCTCC GTCCCGTCCA GGAAAAGGCT TGAGTCGCCA ACAAACACAA 
GGCCTGGAGA TGGTCAAACA CATCATGAGC AGCCTGGAGG ACGAGGACGG CCTGGAGGAG 
GTCTACACAT TCAGTGACGC TCTGGAGAAA CTCTCCATCT TCAAGCGTAT TGAAAGGAGG 
CCGATGGCAT GGCCGTGTCA GCTCACCATC GGCAGCTCTC TGTCTATTCG CATTGTTGGA 
TATAAAGCTG TGACAGAGGA AAAGGTGAAA AAGTCTTGGA CGATTGTGGA CGCTCAGAGT 
CACCAGAGAG ATGACGTGAA GAGAGAGACA GTTTACTGTC TGAACGATGA TGATGAAACT 
GAGGTGCAGA AAGACGACAC AATACAAGGT TACCGTTATG GAAGTGACAT TGTGCCGTTT 
TCAAAGGTGG ACGAGGAGCA GATGAAATAT AAGCATGATG GGAAGTGTTT CTCTGTGCTT 
GGCTTCACTA AACAGGAGCT GATTCCTCGT CATCAGTTTA TGGGAAGCCA AGTTGTCAAA 
GTCTTTGCAC CCAGAGATGA TGAGCATGCA GCAGTTGCTC TGTCCTCTCT GATTCGTGCT 
CTTGATGGTC TAAAGATGGC AGCCATTGTA CGTTATGCTT ACGACCGCCG CAGCAATCCT 
CAAGTGGGCG CCGCGTTTCC CTGCATAAAG AAAAAATATG AATGTCTGCT GTACGTTCAG 
CTGCCGTATA TGGAGGATCT CCGTCAGTTC ACTTTCCCCA TGCTGGAAAA CAACAAGAAG 
TTTATGCCAT CAGGGTCTCA GTTGTCAGCC GTAGATGCGC TGATCGACTC CATGATGCTG 
ATGGAGAAGG ATGAGAATGG AGAAAGTGTG GAGATCTTCA AAGTCAACCA CATCCCAAAC 
CCACAGTTCC AGAGGCTCTT CCAGTGTTTG CATCACCGCG GTGTGAATCC TGATGATCCT 
CTGCCTCCCG TGGATCCGTG GCTCAAGCGG GTCCTGGAAA GACCGCAGGC CGTGTCCGCT 
CGCTGCCAGG CCCCTCTGCG GGACGTCAAG ACCAGCTTCC CTCTCAAAGT GGTGGTGAAA 
AAGAAAGAGC AGAAGACGAG CGCAGACGTG TTCGGCAGCA GTGCTGATGA ACCAGATGCC 
AAGAAAGTCA AAGTGAATGA AGAAACCGAG TTTAACCTGG CTGAGATTAC AGAGGGAAAC 
ATCACATCGG TTGGCAGCGT CAATCCAGCC AGAGATTTCT GCACACTGAT AAGACAGAAG 
ACGGTTTCTT TCGATCAAGC GTGCCAGCAG CTGACCCACA GGATTGAGCA GTTGCTGGGC 
AACAGGAGCA CTGAGTATTA CACCAAGAGC ATCGCCTGCA TCCAGGCCTT CAGGGATCAG 
TCTGTACTGA GCGGAAACGC AGAGCTGTTC AACAGTTACC TGCAGTCTCT GAAGAGGAGC 
ATTGCTGACC GCAGCCTTCA GGACTTCTGG AACCTGCTCG CTCAAGATGC TCTAACGCTG 
ATTAGCAAAG ATGAAGTGGA GGCAAGCACC ATCTCCAAAC AAGAAGCAAA TCAGTTCCTG 
TCATTTGAGC AGAAGCAGGA AGTTGAAGTA GCTCCAGCGC AGGACGACAC TGGAGATGTG 
GATGATCTGC TGGACATGAT GTAA