nfkbiaa cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	nfkbiaa
Entrez Gene ID	406463
Full Name	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
Synonyms	ikbaA,wu:fj16a07,zgc:85769
General protein information	Preferred Names nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a Names nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a NF-kappaB inhibitor alpha-like protein A fj16a07
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_213184.2	NP_998349.2	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	NFKBIA	XP_001087842.1
Canis lupus familiaris (dog)	NFKBIA	XP_537413.3
Bos taurus (cattle)	NFKBIA	NP_001039333.1
Danio rerio (zebrafish)	nfkbiaa	NP_998349.1
Anopheles gambiae (African malaria mosquito)	CACT	XP_317542.4
Pan troglodytes (chimpanzee)	NFKBIA	XP_522823.2
Rattus norvegicus (Norway rat)	Nfkbia	NP_001099190.2
Gallus gallus (chicken)	NFKBIA	NP_001001472.2
Danio rerio (zebrafish)	nfkbiab	NP_955923.1
Homo sapiens (human)	NFKBIA	NP_065390.1
Mus musculus (house mouse)	Nfkbia	NP_035037.2
Xenopus tropicalis (tropical clawed frog)	nfkbia	NP_001004851.1
Drosophila melanogaster (fruit fly)	cact	NP_001260496.1

Gene Ontology
Bibliography

Related articles in PubMed

Notch1a can widely mediate innate immune responses in zebrafish larvae infected with Vibrio parahaemolyticus.
Ji C, Guo X, Dong X, Ren J, Zu Y, Li W, Zhang Q
Fish & shellfish immunology92680-689(2019 Sep)

What makes a bad egg? Egg transcriptome reveals dysregulation of translational machinery and novel fertility genes important for fertilization.
Cheung CT, Nguyen TV, Le Cam A, Patinote A, Journot L, Reynes C, Bobe J
BMC genomics20(1)584(2019 Jul)

3‑Bromo‑5‑(ethoxymethyl)‑1,2‑benzenediol inhibits LPS-induced pro-inflammatory responses by preventing ROS production and downregulating NF-κB in vitro and in a zebrafish model.
Ko EY, Heo SJ, Cho SH, Lee W, Kim SY, Yang HW, Ahn G, Cha SH, Kwon SH, Jeong MS, Lee KP, Jeon YJ, Kim KN
International immunopharmacology6798-105(2019 Feb)

Tenacissoside H exerts an anti-inflammatory effect by regulating the nf-κb and p38 pathways in zebrafish.
Li JJ, Zhang Y, Han LW, Tian QP, He QX, Wang XM, Sun C, Han J, Liu KC
Fish & shellfish immunology83205-212(2018 Dec)

Silica nanoparticles trigger hepatic lipid-metabolism disorder in vivo and in vitro.
Duan J, Liang S, Feng L, Yu Y, Sun Z
International journal of nanomedicine137303-7318(2018)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following nfkbiaa gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the nfkbiaa cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa40873	NM_213184.2 Latest version!	Danio rerio nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a (nfkbiaa), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

nfkbiaa ( NM_213184.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_998349.2 Danio rerio nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a (nfkbiaa), mRNA.

Price & Availability↑

CloneID	ODa40873
Clone ID Related Accession (Same CDS sequence)	NM_213184.2
Accession Version	NM_213184.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 933bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1578067200000
Organism	Danio rerio(zebrafish)
Product	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CU855900.3, EH437254.1 and EH466098.1. On Aug 25, 2015 this sequence version replaced NM_213184.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: GDQH01002945.1, GFIL01028195.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATTTAC ACAGAGCCGC AATGCTGAAC TTTGTGGATT GTAATGTTGA TGAAATGGAC 
ACGAAAAACA GGAAAACGCA GCAGTGCGAG GATCGCGTCG ACAGCGGCGT GGACTCGCTA 
AAAGAAGAGG AATATGAGAC GCGGGAGATT TCGGAGGAGA TGGAGAAATT GACTATAGCA 
AGCCTGAAGG AGACAATATG CGAGCCTTGG GCTAAAGTAG TCACCGAGGA CGGAGACACG 
TATCTGCACC TTGCCATCAT TCACGAGGCA GAGGATTATG CCGTGCAGAT CATCAAACAG 
TGCCAGAACG ACCCGTACCT GAACAGACAG AACAACCAGA GACAGACTGC TCTGCATCTG 
GCCGTTGTCA CAGAACAGCC ACAAATGGTG GAAAGACTCC TGAAAGCCGG CTGCGACCCT 
CAGCTTGTTG ATCAGAGCGG AAACACAGCC CTGCACCTCG CCTGCAAACA AGGCTCGCTG 
GCGTGTTTCT CAGTCCTCAC TCAGATTCAG ACCCAGCACC TGCGTTCCAT TCTTACCTTC 
CCTAACTACA GCGGACACAC GTGCCTTCAT ATAGCAGCCA TTAATAATTA CCTGTCCATG 
GTGGAGAGTC TGGTCCAGCT TGGGGCAGAT GTAGACGCAA AGGAGCAGTG TAGTGGCCGT 
ACGTCGCTCC ATTTGGCCGT AGACCTGCAG AACCTGGATC TGGTGCACAC ACTCATAGCT 
CTGGGAGCCG ATGCCAATAG TTTAACCTAC GGCGGATACA CAGCGTACCA CCTGACCTTC 
GGCAGACACA ACAGCGAGAT CCAGAGGCAG CTTTACAGCC GGACAGCCCT TAAATTCACA 
GTCATGCCAG AGAGCGAATC GGAGGAGAGC GAAGATGAGC TCATGTCTGA GGACGATTGT 
ATTTATGATG ACATCCGGCT CTGTGGGAGA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_998349.2
CDS	40..972
Translation	MDLHRAAMLNFVDCNVDEMDTKNRKTQQCEDRVDSGVDSLKEEEYETREISEEMEKLTIASLKETICEPWAKVVTEDGDTYLHLAIIHEAEDYAVQIIKQCQNDPYLNRQNNQRQTALHLAVVTEQPQMVERLLKAGCDPQLVDQSGNTALHLACKQGSLACFSVLTQIQTQHLRSILTFPNYSGHTCLHIAAINNYLSMVESLVQLGADVDAKEQCSGRTSLHLAVDLQNLDLVHTLIALGADANSLTYGGYTAYHLTFGRHNSEIQRQLYSRTALKFTVMPESESEESEDELMSEDDCIYDDIRLCGR

Target ORF information:

RefSeq Version	NM_213184.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a (nfkbiaa), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_213184.2

ORF Insert Sequence:

ATGGATTTAC ACAGAGCCGC AATGCTGAAC TTTGTGGATT GTAATGTTGA TGAAATGGAC 
ACGAAAAACA GGAAAACGCA GCAGTGCGAG GATCGCGTCG ACAGCGGCGT GGACTCGCTA 
AAAGAAGAGG AATATGAGAC GCGGGAGATT TCGGAGGAGA TGGAGAAATT GACTATAGCA 
AGCCTGAAGG AGACAATATG CGAGCCTTGG GCTAAAGTAG TCACCGAGGA CGGAGACACG 
TATCTGCACC TTGCCATCAT TCACGAGGCA GAGGATTATG CCGTGCAGAT CATCAAACAG 
TGCCAGAACG ACCCGTACCT GAACAGACAG AACAACCAGA GACAGACTGC TCTGCATCTG 
GCCGTTGTCA CAGAACAGCC ACAAATGGTG GAAAGACTCC TGAAAGCCGG CTGCGACCCT 
CAGCTTGTTG ATCAGAGCGG AAACACAGCC CTGCACCTCG CCTGCAAACA AGGCTCGCTG 
GCGTGTTTCT CAGTCCTCAC TCAGATTCAG ACCCAGCACC TGCGTTCCAT TCTTACCTTC 
CCTAACTACA GCGGACACAC GTGCCTTCAT ATAGCAGCCA TTAATAATTA CCTGTCCATG 
GTGGAGAGTC TGGTCCAGCT TGGGGCAGAT GTAGACGCAA AGGAGCAGTG TAGTGGCCGT 
ACGTCGCTCC ATTTGGCCGT AGACCTGCAG AACCTGGATC TGGTGCACAC ACTCATAGCT 
CTGGGAGCCG ATGCCAATAG TTTAACCTAC GGCGGATACA CAGCGTACCA CCTGACCTTC 
GGCAGACACA ACAGCGAGAT CCAGAGGCAG CTTTACAGCC GGACAGCCCT TAAATTCACA 
GTCATGCCAG AGAGCGAATC GGAGGAGAGC GAAGATGAGC TCATGTCTGA GGACGATTGT 
ATTTATGATG ACATCCGGCT CTGTGGGAGA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Notch1a can widely mediate innate immune responses in zebrafish larvae infected with Vibrio parahaemolyticus.
Fish & shellfish immunology92680-689(2019 Sep)
Ji C,Guo X,Dong X,Ren J,Zu Y,Li W,Zhang Q

What makes a bad egg? Egg transcriptome reveals dysregulation of translational machinery and novel fertility genes important for fertilization.
BMC genomics20(1)584(2019 Jul)
Cheung CT,Nguyen TV,Le Cam A,Patinote A,Journot L,Reynes C,Bobe J

3‑Bromo‑5‑(ethoxymethyl)‑1,2‑benzenediol inhibits LPS-induced pro-inflammatory responses by preventing ROS production and downregulating NF-κB in vitro and in a zebrafish model.
International immunopharmacology6798-105(2019 Feb)
Ko EY,Heo SJ,Cho SH,Lee W,Kim SY,Yang HW,Ahn G,Cha SH,Kwon SH,Jeong MS,Lee KP,Jeon YJ,Kim KN

Tenacissoside H exerts an anti-inflammatory effect by regulating the nf-κb and p38 pathways in zebrafish.
Fish & shellfish immunology83205-212(2018 Dec)
Li JJ,Zhang Y,Han LW,Tian QP,He QX,Wang XM,Sun C,Han J,Liu KC

Silica nanoparticles trigger hepatic lipid-metabolism disorder in vivo and in vitro.
International journal of nanomedicine137303-7318(2018)
Duan J,Liang S,Feng L,Yu Y,Sun Z

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nfkbiaa cDNA ORF clone, Danio rerio(zebrafish)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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