rrm2b cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	rrm2b
Entrez Gene ID	368909
Full Name	ribonucleotide reductase M2 b
Synonyms	fb72h01,fb93b05,rrm2,si:zc215i13.5,wu:fb72h01,wu:fb93b05
General protein information	Preferred Names ribonucleotide reductase M2 b Names ribonucleoside-diphosphate reductase subunit M2 B
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001007163.2	NP_001007164.1	ribonucleoside-diphosphate reductase subunit M2 B

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	RRM2B	XP_539109.3
Mus musculus (house mouse)	Rrm2b	NP_955770.1
Homo sapiens (human)	RRM2B	NP_001165948.1
Gallus gallus (chicken)	RRM2B	XP_418364.2
Pan troglodytes (chimpanzee)	RRM2B	XP_001153916.1
Bos taurus (cattle)	RRM2B	XP_002692807.1
Danio rerio (zebrafish)	rrm2b	NP_001007164.1
Arabidopsis thaliana (thale cress)	RNR2A	NP_189000.1
Rattus norvegicus (Norway rat)	Rrm2b	NP_001124015.1
Xenopus tropicalis (tropical clawed frog)	rrm2b	NP_001119973.1

Gene Ontology
Bibliography

Related articles in PubMed

Tritiated water exposure disrupts myofibril structure and induces mis-regulation of eye opacity and DNA repair genes in zebrafish early life stages.
Arcanjo C, Armant O, Floriani M, Cavalie I, Camilleri V, Simon O, Orjollet D, Adam-Guillermin C, Gagnaire B
Aquatic toxicology (Amsterdam, Netherlands)200114-126(2018 Jul)

p53-Dependent DNA damage response sensitive to editing-defective tRNA synthetase in zebrafish.
Song Y, Shi Y, Carland TM, Lian S, Sasaki T, Schork NJ, Head SR, Kishi S, Schimmel P
Proceedings of the National Academy of Sciences of the United States of America113(30)8460-5(2016 07)

RNA sequencing provides insights into the toxicogenomic response of ZF4 cells to methyl methanesulfonate.
Li Z, Long Y, Zhong L, Song G, Zhang X, Yuan L, Cui Z, Dai H
Journal of applied toxicology : JAT36(1)94-104(2016 Jan)

A transgenic zebrafish model expressing KIT-D816V recapitulates features of aggressive systemic mastocytosis.
Balci TB, Prykhozhij SV, Teh EM, Da'as SI, McBride E, Liwski R, Chute IC, Leger D, Lewis SM, Berman JN
British journal of haematology167(1)48-61(2014 Oct)

Identification and characterization of alternative promoters, transcripts and protein isoforms of zebrafish R2 gene.
Shang H, Li Q, Feng G, Cui Z
PloS one6(8)e24089(2011)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following rrm2b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the rrm2b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa24266	NM_001007163.2 Latest version!	Danio rerio ribonucleotide reductase M2 b (rrm2b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

rrm2b ( NM_001007163.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001007164.1 Danio rerio ribonucleotide reductase M2 b (rrm2b), mRNA.

Price & Availability↑

CloneID	ODa24266
Clone ID Related Accession (Same CDS sequence)	NM_001007163.2
Accession Version	NM_001007163.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1050bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1545321600000
Organism	Danio rerio(zebrafish)
Product	ribonucleoside-diphosphate reductase subunit M2 B
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL807244.7. On May 29, 2010 this sequence version replaced NM_001007163.1. ##Evidence-Data-START## Transcript exon combination :: GDQH01009791.1, GDQQ01015583.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476755, SAMEA4476774 [ECO:0000348] ##Evidence-Data-END##

ATGAACTCCT GCACAAGCAA CACTCCGACG GTTATTACGG GATATCAGAA CGGTCACAAG 
GATGTCGACC CAAACAGTGT TGAAGATGAG CCTCTGCTCA GAGAGAATCC CAAACGATTT 
GTCATTTTCC CTATTCAGTA TCCAGACATC TGGAAAATGT ACAAACAAGC ACAGGCTTCT 
TTCTGGACAG TTGAGGAGGT GGATTTATCA AAGGATTTAA CTCACTGGGA CGGCCTGAAG 
TCTGAAGAGA AACACTTCAT ATCACATGTA TTGGCTTTCT TTGCGGCAAG TGATGGGATA 
GTCAATGAGA ACCTGGTCCA GAGGTTCAGT CAGGAGGTGC AGCTCCCCGA GGCTCGTTCC 
TTCTACGGCT TTCAAATATT AATTGAGAAC GTGCACTCAG AGATGTACAG CATGCTCATT 
AACACCTACA TTAGGGATCT GAAAGAGAGA GACTATTTGT TTAATGCAGT TCAGACCATG 
CCCTGTGTGA GGCGGAAAGC AGACTGGGCC TTACAGTGGA TTTCAGACAC AAACTCAACT 
TTCGGTGAGC GGTTGGTAGC GTTTGCAGCA GTGGAAGGCA TTTTTTTCTC AGGATCATTT 
GCTGCCATCT ATTGGTTAAA GAAAAGAGGC CTGATGCCTG GACTCACCTA CTCCAATGAG 
CTCATCAGCA GAGACGAGGG CCTACACTGC AATTTTGCCT GTTTAATATA CAGTTACTTA 
GTGAAAAAAC CTTCTGTTGA CCGAGTGAAT GACATTATCG CTAAAGCTGT GAGCATTGAA 
CAGGAGTTTC TCACAGAAGC TTTACCAGTC AATTTGATCG GGATGAACTG CTCTCTCATG 
AAGCAGTACA TTGAGTTTGT TGCTGACCGC TTGCTGACCG ACTTAGGATT GCCCAAAGCT 
TACTGTTCAG AAAACCCCTT CGACTTCATG GAGTCCATTT CATTGGAGGG GAAAACAAAT 
TTCTTTGAGA AGCGAGTGGC CGAATACCAG CGACTTGGAG TGATGTCAAA TGTTAAGGAT 
TGTGAATTCA CACTGGATGC AGATTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001007164.1
CDS	69..1118
Translation	MNSCTSNTPTVITGYQNGHKDVDPNSVEDEPLLRENPKRFVIFPIQYPDIWKMYKQAQASFWTVEEVDLSKDLTHWDGLKSEEKHFISHVLAFFAASDGIVNENLVQRFSQEVQLPEARSFYGFQILIENVHSEMYSMLINTYIRDLKERDYLFNAVQTMPCVRRKADWALQWISDTNSTFGERLVAFAAVEGIFFSGSFAAIYWLKKRGLMPGLTYSNELISRDEGLHCNFACLIYSYLVKKPSVDRVNDIIAKAVSIEQEFLTEALPVNLIGMNCSLMKQYIEFVADRLLTDLGLPKAYCSENPFDFMESISLEGKTNFFEKRVAEYQRLGVMSNVKDCEFTLDADF

Target ORF information:

RefSeq Version	NM_001007163.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio ribonucleotide reductase M2 b (rrm2b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001007163.2

ORF Insert Sequence:

ATGAACTCCT GCACAAGCAA CACTCCGACG GTTATTACGG GATATCAGAA CGGTCACAAG 
GATGTCGACC CAAACAGTGT TGAAGATGAG CCTCTGCTCA GAGAGAATCC CAAACGATTT 
GTCATTTTCC CTATTCAGTA TCCAGACATC TGGAAAATGT ACAAACAAGC ACAGGCTTCT 
TTCTGGACAG TTGAGGAGGT GGATTTATCA AAGGATTTAA CTCACTGGGA CGGCCTGAAG 
TCTGAAGAGA AACACTTCAT ATCACATGTA TTGGCTTTCT TTGCGGCAAG TGATGGGATA 
GTCAATGAGA ACCTGGTCCA GAGGTTCAGT CAGGAGGTGC AGCTCCCCGA GGCTCGTTCC 
TTCTACGGCT TTCAAATATT AATTGAGAAC GTGCACTCAG AGATGTACAG CATGCTCATT 
AACACCTACA TTAGGGATCT GAAAGAGAGA GACTATTTGT TTAATGCAGT TCAGACCATG 
CCCTGTGTGA GGCGGAAAGC AGACTGGGCC TTACAGTGGA TTTCAGACAC AAACTCAACT 
TTCGGTGAGC GGTTGGTAGC GTTTGCAGCA GTGGAAGGCA TTTTTTTCTC AGGATCATTT 
GCTGCCATCT ATTGGTTAAA GAAAAGAGGC CTGATGCCTG GACTCACCTA CTCCAATGAG 
CTCATCAGCA GAGACGAGGG CCTACACTGC AATTTTGCCT GTTTAATATA CAGTTACTTA 
GTGAAAAAAC CTTCTGTTGA CCGAGTGAAT GACATTATCG CTAAAGCTGT GAGCATTGAA 
CAGGAGTTTC TCACAGAAGC TTTACCAGTC AATTTGATCG GGATGAACTG CTCTCTCATG 
AAGCAGTACA TTGAGTTTGT TGCTGACCGC TTGCTGACCG ACTTAGGATT GCCCAAAGCT 
TACTGTTCAG AAAACCCCTT CGACTTCATG GAGTCCATTT CATTGGAGGG GAAAACAAAT 
TTCTTTGAGA AGCGAGTGGC CGAATACCAG CGACTTGGAG TGATGTCAAA TGTTAAGGAT 
TGTGAATTCA CACTGGATGC AGATTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Tritiated water exposure disrupts myofibril structure and induces mis-regulation of eye opacity and DNA repair genes in zebrafish early life stages.
Aquatic toxicology (Amsterdam, Netherlands)200114-126(2018 Jul)
Arcanjo C,Armant O,Floriani M,Cavalie I,Camilleri V,Simon O,Orjollet D,Adam-Guillermin C,Gagnaire B

p53-Dependent DNA damage response sensitive to editing-defective tRNA synthetase in zebrafish.
Proceedings of the National Academy of Sciences of the United States of America113(30)8460-5(2016 07)
Song Y,Shi Y,Carland TM,Lian S,Sasaki T,Schork NJ,Head SR,Kishi S,Schimmel P

RNA sequencing provides insights into the toxicogenomic response of ZF4 cells to methyl methanesulfonate.
Journal of applied toxicology : JAT36(1)94-104(2016 Jan)
Li Z,Long Y,Zhong L,Song G,Zhang X,Yuan L,Cui Z,Dai H

A transgenic zebrafish model expressing KIT-D816V recapitulates features of aggressive systemic mastocytosis.
British journal of haematology167(1)48-61(2014 Oct)
Balci TB,Prykhozhij SV,Teh EM,Da'as SI,McBride E,Liwski R,Chute IC,Leger D,Lewis SM,Berman JN

Identification and characterization of alternative promoters, transcripts and protein isoforms of zebrafish R2 gene.
PloS one6(8)e24089(2011)
Shang H,Li Q,Feng G,Cui Z

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rrm2b cDNA ORF clone, Danio rerio(zebrafish)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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