lpar1 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	lpar1
Entrez Gene ID	368461
Full Name	lysophosphatidic acid receptor 1
Synonyms	edg2,si:dz22b13.1,si:dz46m7.1,zgc:92157
General protein information	Preferred Names lysophosphatidic acid receptor 1 Names lysophosphatidic acid receptor 1 endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2 lpa1 zlpa1
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001004502.2	NP_001004502.2	lysophosphatidic acid receptor 1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Lpar1	NP_446388.1
Xenopus tropicalis (tropical clawed frog)	lpar1	NP_001096313.1
Macaca mulatta (Rhesus monkey)	LPAR1	XP_001106044.1
Canis lupus familiaris (dog)	LPAR1	XP_532031.3
Homo sapiens (human)	LPAR1	NP_001392.2
Gallus gallus (chicken)	LPAR1	NP_001108554.1
Danio rerio (zebrafish)	lpar1	NP_001004502.2
Bos taurus (cattle)	LPAR1	NP_776472.1
Pan troglodytes (chimpanzee)	LPAR1	XP_001147476.1
Mus musculus (house mouse)	Lpar1	NP_766577.1

Gene Ontology
Bibliography

Related articles in PubMed

Role of ectonucleotide pyrophosphatase/phosphodiesterase 2 in the midline axis formation of zebrafish.
Frisca F, Colquhoun D, Goldshmit Y, Änkö ML, Pébay A, Kaslin J
Scientific reports637678(2016 11)

MicroRNAs regulate gene plasticity during cold shock in zebrafish larvae.
Hung IC, Hsiao YC, Sun HS, Chen TM, Lee SJ
BMC genomics17(1)922(2016 11)

ATX-LPA1 axis contributes to proliferation of chondrocytes by regulating fibronectin assembly leading to proper cartilage formation.
Nishioka T, Arima N, Kano K, Hama K, Itai E, Yukiura H, Kise R, Inoue A, Kim SH, Solnica-Krezel L, Moolenaar WH, Chun J, Aoki J
Scientific reports623433(2016 Mar)

Lysophosphatidic acid acts as a nutrient-derived developmental cue to regulate early hematopoiesis.
Li H, Yue R, Wei B, Gao G, Du J, Pei G
The EMBO journal33(12)1383-96(2014 Jun)

Overexpression of autotaxin, a lysophosphatidic acid-producing enzyme, enhances cardia bifida induced by hypo-sphingosine-1-phosphate signaling in zebrafish embryo.
Nakanaga K, Hama K, Kano K, Sato T, Yukiura H, Inoue A, Saigusa D, Tokuyama H, Tomioka Y, Nishina H, Kawahara A, Aoki J
Journal of biochemistry155(4)235-41(2014 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following lpar1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the lpar1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa01541	NM_001004502.2 Latest version!	Danio rerio lysophosphatidic acid receptor 1 (lpar1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

lpar1 ( NM_001004502.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001004502.2 Danio rerio lysophosphatidic acid receptor 1 (lpar1), mRNA.

Price & Availability↑

CloneID	ODa01541
Clone ID Related Accession (Same CDS sequence)	NM_001004502.2
Accession Version	NM_001004502.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1041bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1498233600000
Organism	Danio rerio(zebrafish)
Product	lysophosphatidic acid receptor 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC075909.1. On Nov 22, 2004 this sequence version replaced NM_001004502.1. ##Evidence-Data-START## Transcript exon combination :: BC075909.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGGATGATA GACAATGCTA CTACAACGAA ACCATAGCCT TTTTTTACAA TCGTAGTCAG 
AAGTATCTGG CCACAGAATG GAACGCTGTA AGCAAGCTAG TCATGGGACT TGGGATTACA 
GTATGCATTT TCATAATGCT AGCAAACCTG CTGGTGATGG TGGCCATCTA CATCAACCGC 
CGCTTTCACT TTCCAATCTA CTATCTAATG GCTAACCTAG CAGCCGCGGA CTTCTTTGCA 
GGACTTGCCT ATTTCTACTT GATGTTTAAC ACGGGGCCCA ATACAAGAAG GCTAACGGTT 
AGCACGTGGT TGCTTCGACA AGGCCTCATC GATACAAGCC TTACAGCCTC AGTTGCTAAC 
TTGCTAGCTA TAGCCATTGA GCGCCACATA ACTGTGTTCC GCATGCAGCT CCATACCCGC 
ATGAGCAATC GGAGGGTAGT TGTGGTTATA GTCATCATCT GGACCATGTC TATCGTCATG 
GGGGCTATTC CTAGCGTGGG CTGGAACTGC ATCTGCGCCA TAGACACTTG TTCCAATATG 
GCCCCACTCT ACAGCAACTC GTACCTGGGC TTCTGGGCAA TCTTTAACCT GGTGACCTTC 
GTGGTGATGG TCGTACTTTA TGCACACATA TTTATGTATG TGCGTCAGCG GACCATGAGG 
ATGTCCCGGC ACAGCTCGGG TCAACGGCGT AACAGGGATA CTATGATGAG CTTGCTGAAA 
ACTGTCGTGA TTGTATTGGG TGCTTTCATC GTGTGCTGGA CGCCCGGTTT GGTTATTCTT 
CTGCTGGACG TGGTCTGCGC CAACTGCAAC GTCCTGACCT ACGAAAAATT CTTTCTTCTG 
TTAGCGGAAT TCAACTCCGC CATGAACCCA ATCATTTACT CGTACCGGGA CAAGGAGATG 
AGCATCACAT TCAAACAGAT CCTGTGCTGT CAGCGACAGG AGAACGTGAA CGGTACTGCC 
GAGGGGTCCG ACCGGTCTGC ATCCTCCATC AACCACACGG TTCTGAGCGG CGCTCACCAT 
AATGACCATT CAGTGGTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001004502.2
CDS	252..1292
Translation	MDDRQCYYNETIAFFYNRSQKYLATEWNAVSKLVMGLGITVCIFIMLANLLVMVAIYINRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVIIWTMSIVMGAIPSVGWNCICAIDTCSNMAPLYSNSYLGFWAIFNLVTFVVMVVLYAHIFMYVRQRTMRMSRHSSGQRRNRDTMMSLLKTVVIVLGAFIVCWTPGLVILLLDVVCANCNVLTYEKFFLLLAEFNSAMNPIIYSYRDKEMSITFKQILCCQRQENVNGTAEGSDRSASSINHTVLSGAHHNDHSVV

Target ORF information:

RefSeq Version	NM_001004502.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio lysophosphatidic acid receptor 1 (lpar1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001004502.2

ORF Insert Sequence:

ATGGATGATA GACAATGCTA CTACAACGAA ACCATAGCCT TTTTTTACAA TCGTAGTCAG 
AAGTATCTGG CCACAGAATG GAACGCTGTA AGCAAGCTAG TCATGGGACT TGGGATTACA 
GTATGCATTT TCATAATGCT AGCAAACCTG CTGGTGATGG TGGCCATCTA CATCAACCGC 
CGCTTTCACT TTCCAATCTA CTATCTAATG GCTAACCTAG CAGCCGCGGA CTTCTTTGCA 
GGACTTGCCT ATTTCTACTT GATGTTTAAC ACGGGGCCCA ATACAAGAAG GCTAACGGTT 
AGCACGTGGT TGCTTCGACA AGGCCTCATC GATACAAGCC TTACAGCCTC AGTTGCTAAC 
TTGCTAGCTA TAGCCATTGA GCGCCACATA ACTGTGTTCC GCATGCAGCT CCATACCCGC 
ATGAGCAATC GGAGGGTAGT TGTGGTTATA GTCATCATCT GGACCATGTC TATCGTCATG 
GGGGCTATTC CTAGCGTGGG CTGGAACTGC ATCTGCGCCA TAGACACTTG TTCCAATATG 
GCCCCACTCT ACAGCAACTC GTACCTGGGC TTCTGGGCAA TCTTTAACCT GGTGACCTTC 
GTGGTGATGG TCGTACTTTA TGCACACATA TTTATGTATG TGCGTCAGCG GACCATGAGG 
ATGTCCCGGC ACAGCTCGGG TCAACGGCGT AACAGGGATA CTATGATGAG CTTGCTGAAA 
ACTGTCGTGA TTGTATTGGG TGCTTTCATC GTGTGCTGGA CGCCCGGTTT GGTTATTCTT 
CTGCTGGACG TGGTCTGCGC CAACTGCAAC GTCCTGACCT ACGAAAAATT CTTTCTTCTG 
TTAGCGGAAT TCAACTCCGC CATGAACCCA ATCATTTACT CGTACCGGGA CAAGGAGATG 
AGCATCACAT TCAAACAGAT CCTGTGCTGT CAGCGACAGG AGAACGTGAA CGGTACTGCC 
GAGGGGTCCG ACCGGTCTGC ATCCTCCATC AACCACACGG TTCTGAGCGG CGCTCACCAT 
AATGACCATT CAGTGGTCTG A