stat6 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	stat6
Entrez Gene ID	337413
Full Name	signal transducer and activator of transcription 6, interleukin-4 induced
Synonyms	sb:eu508,stat7,wu:fj66g07
General protein information	Preferred Names signal transducer and activator of transcription 6, interleukin-4 induced Names signal transducer and activator of transcription 6, interleukin-4 induced signal transducer and activator of transcription 7
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001130590.1	NP_001124062.1	signal transducer and activator of transcription 6, interleukin-4 induced

Pathways from BioSystems

Homologies

Bos taurus (cattle)	STAT6	NP_001192430.1
Canis lupus familiaris (dog)	STAT6	XP_003431490.1
Macaca mulatta (Rhesus monkey)	STAT6	XP_002798683.1
Danio rerio (zebrafish)	stat6	NP_001124062.1
Homo sapiens (human)	STAT6	NP_001171550.1
Rattus norvegicus (Norway rat)	Stat6	NP_001037715.1
Xenopus tropicalis (tropical clawed frog)	stat6	XP_002939755.1
Mus musculus (house mouse)	Stat6	NP_033310.2
Pan troglodytes (chimpanzee)	STAT6	XP_003952193.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification of DEAD-Box RNA Helicase DDX41 as a Trafficking Protein That Involves in Multiple Innate Immune Signaling Pathways in a Zebrafish Model.
Ma JX, Li JY, Fan DD, Feng W, Lin AF, Xiang LX, Shao JZ
Frontiers in immunology91327(2018)

Effect of ES products from Anisakis (Nematoda: Anisakidae) on experimentally induced colitis in adult zebrafish.
Haarder S, Kania PW, Holm TL, von Gersdorff Jørgensen L, Buchmann K
Parasite immunology39(10)(2017 Oct)

Zebrafish STAT6 negatively regulates IFNφ1 production by attenuating the kinase activity of TANK-binding kinase 1.
Li S, Lu LF, LaPatra SE, Chen DD, Zhang YA
Developmental and comparative immunology67189-201(2017 02)

Immunomodulatory effects of excretory/secretory compounds from Contracaecum osculatum larvae in a zebrafish inflammation model.
Mehrdana F, Kania PW, Nazemi S, Buchmann K
PloS one12(7)e0181277(2017)

IL4/STAT6 Signaling Activates Neural Stem Cell Proliferation and Neurogenesis upon Amyloid-β42 Aggregation in Adult Zebrafish Brain.
Bhattarai P, Thomas AK, Cosacak MI, Papadimitriou C, Mashkaryan V, Froc C, Reinhardt S, Kurth T, Dahl A, Zhang Y, Kizil C
Cell reports17(4)941-948(2016 10)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following stat6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the stat6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa38809	NM_001130590.1 Latest version!	Danio rerio signal transducer and activator of transcription 6, interleukin-4 induced (stat6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

stat6 ( NM_001130590.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001124062.1 Danio rerio signal transducer and activator of transcription 6, interleukin-4 induced (stat6), mRNA.

Price & Availability↑

CloneID	ODa38809
Clone ID Related Accession (Same CDS sequence)	NM_001130590.1
Accession Version	NM_001130590.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2277bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1540569600000
Organism	Danio rerio(zebrafish)
Product	signal transducer and activator of transcription 6, interleukin-4 induced
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC162530.1. On Jun 10, 2016 this sequence version replaced NM_001146352.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC162530.1, AM941850.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGGCGCAGT GGGCGCAAAT GACCCAGCAC ATACAGTTCT TGACAACTGA GGTGCTGAAT 
GAACTCTACC CAGTCACGTT TCCTCTGGAT ATCAGGCACT ATTTGGCCAG CTGGATAGAG 
GGGCAGCAAT GGGATAGCTT TGATGTGGAC AACAGGGAAC AGGAATCTCA GGCTCAATTA 
CTGTCGGATC AGATGGTGAT GTTGCTGCAT CAAGTGGCCA AGCAGAACCC TAATGTGGTG 
GAGAAGGTCA AACTACAGCA TATGAGCAAG AACTGGAGTG TGCTTTACCC ACAACCCTTA 
CAACTTGTGA GGACAGTTCG GGAGATTCTA AGGAAAGAAA GACTAATTTT ATCACAGACT 
AATATGCAGT TCCCTCCCTT CGCACCTCCA CCTACCAACG GCATCCCACA ACAAGCATGG 
GAGGAGAAAA AGACTGATGT GGAGAATCTA ATGTCCAAAG TTATGGAAAT TCAGAATCGC 
CGCCAAACAC TTCATCAGCT TCAAGAGGAA CTGAATTGGG AGAAAGAGAC GATTCAAGGT 
CTCAGTGAGA TGGATACAGG TGCTAAACAG AAACGCATTC AGCAAATTGA GTATAACGCA 
ACAATTTGTG CACAGGAGCG TGTACAGTTT CTTTGCGATG CCGTAGGAGC TCTGGAGCAA 
TGTCAGTCCT CTTTAATGCT TAAAATTGAG TCCTGGAGGT GGGAACAGCA TCGATCAACC 
ATTGGCATGC CCTTCAATGA CATCCTCGAC CATCTGCAGA CATGGAGTGA GCAGTTGCTC 
ATAGTGAATG GTAACCTGAG ACAGGAGCTC ATGCTGATGA AAGTGGACCA TGGAGATGCT 
GAACGGCTTC GAACTTTGGA GGAAAACCTG GCACGTCTAC TCAAGACTCT CATTCAGAAT 
TCATTGGTAG TAGAGAAGCA GCCTCCCCAG GTCATCAAAA CTCAGTCCAA GTTTTCCACC 
ACTGTACGCT ATCTGCTGGG AGACAAGATG GCCCCTGGAA AACCTGTCTT ATTAAAGGCT 
CAGATTATCA CCGAGGCACA AGCAAGAAAC CTGGGTCAAC AAAGTGTCAT TCCCAATGAA 
AATGTTGGAG AACTTCTTAA TAGTACGACG ATCTTGGAGC ACAACACCAC CAGCAAGAAC 
ACCTGTGCCA CCTTTAGAAA CATGTCCATA AGGAGGATCA AACGGGCTGA CAGGAAGGGC 
TCTGAATCAG TGACTGAGGA AAAGTTTGCA TTGTTGTTTA CCACAGATAT AACCATCACC 
GGCGGTGAGA GGCCATACAG CCTTCAGAGC ATCTCTCTTC CTGTGGTTGT AATTGTACAC 
GGTAGTCAGG AAATCAATGC CATGGCCACC ATCATATGGG ACTGCGCCTT CTCTGAGCCA 
AACAGGATAC CATTCCTTGT TCCTGAGCGT GTGTCCTGGC AGCAGATGTG TGGGGCTCTT 
AGCAGTAAGT TCATGTCTGA GGTCCAGACA ACCCGGGGCC TGGACCCATT AAACCTACGC 
TTTCTGGGCC AAAAGATCTT TGATCAACCT GATCACCCTG GAGATTTCGA AAACATGCTT 
GTTTCCTGGG CTCAATTCAA CAAGGAAGTT CTGCCTGGTC GAAACTTCAC CTTCTGGCAG 
TGGTTTGAAG GGGCAATAGA CCTAACTAAG AGATGCCTAC GAGACTATTG GACAGATGGA 
TTGATCTTCG GCTTTATTGG AAAACAGTAC ATCCACTGCA TGCTGCAGGA TAAAACCAAC 
GGCTTCTTCC TTCTGCGCTT CAGTGACTCA GAAATTGGTG GCATCACCAT TGCATATGTG 
GAACCCACTG AAAACGGAGG CAGGAGAGTC CAGAATATTC AGCCTTTCAC CAAAAAGGAT 
CTGGACTCAG CTGGCCTTGG CGATCGCATT CGGGACATTA GCTGCATCAG TCATGTATAT 
CCAGGCATTC CAAAGAATGA AGCATTTAAG AAATACTTTA CAGTGCCCTC CGCTCCTAAT 
GCTGATGGAT ACCTGCCTTT CAAGCTTACA ACAGTTGTCA ACCCAGGAGA CAATAGCACC 
TCCACTAACA ACATAACCTC TGAGAATATC TCTATGAATT TTATTTCACC ATCTACGTCT 
CAGGCATTTG GGCAAAACAT GAATCAGGAC ATATATAATC AACATTGTAC GCCTTCATAT 
AGTATGCCAG ATGACATCAT GCCTCCCCAA CCAATGTACC CGACAGACAT GCAGGTAAAC 
CCCCCTGACG AATTTTCAGA AATGGAGGAA TTTGAGGGAC TTCTGTCATC TATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001124062.1
CDS	136..2412
Translation	MAQWAQMTQHIQFLTTEVLNELYPVTFPLDIRHYLASWIEGQQWDSFDVDNREQESQAQLLSDQMVMLLHQVAKQNPNVVEKVKLQHMSKNWSVLYPQPLQLVRTVREILRKERLILSQTNMQFPPFAPPPTNGIPQQAWEEKKTDVENLMSKVMEIQNRRQTLHQLQEELNWEKETIQGLSEMDTGAKQKRIQQIEYNATICAQERVQFLCDAVGALEQCQSSLMLKIESWRWEQHRSTIGMPFNDILDHLQTWSEQLLIVNGNLRQELMLMKVDHGDAERLRTLEENLARLLKTLIQNSLVVEKQPPQVIKTQSKFSTTVRYLLGDKMAPGKPVLLKAQIITEAQARNLGQQSVIPNENVGELLNSTTILEHNTTSKNTCATFRNMSIRRIKRADRKGSESVTEEKFALLFTTDITITGGERPYSLQSISLPVVVIVHGSQEINAMATIIWDCAFSEPNRIPFLVPERVSWQQMCGALSSKFMSEVQTTRGLDPLNLRFLGQKIFDQPDHPGDFENMLVSWAQFNKEVLPGRNFTFWQWFEGAIDLTKRCLRDYWTDGLIFGFIGKQYIHCMLQDKTNGFFLLRFSDSEIGGITIAYVEPTENGGRRVQNIQPFTKKDLDSAGLGDRIRDISCISHVYPGIPKNEAFKKYFTVPSAPNADGYLPFKLTTVVNPGDNSTSTNNITSENISMNFISPSTSQAFGQNMNQDIYNQHCTPSYSMPDDIMPPQPMYPTDMQVNPPDEFSEMEEFEGLLSSI

Target ORF information:

RefSeq Version	NM_001130590.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio signal transducer and activator of transcription 6, interleukin-4 induced (stat6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001130590.1

ORF Insert Sequence:

ATGGCGCAGT GGGCGCAAAT GACCCAGCAC ATACAGTTCT TGACAACTGA GGTGCTGAAT 
GAACTCTACC CAGTCACGTT TCCTCTGGAT ATCAGGCACT ATTTGGCCAG CTGGATAGAG 
GGGCAGCAAT GGGATAGCTT TGATGTGGAC AACAGGGAAC AGGAATCTCA GGCTCAATTA 
CTGTCGGATC AGATGGTGAT GTTGCTGCAT CAAGTGGCCA AGCAGAACCC TAATGTGGTG 
GAGAAGGTCA AACTACAGCA TATGAGCAAG AACTGGAGTG TGCTTTACCC ACAACCCTTA 
CAACTTGTGA GGACAGTTCG GGAGATTCTA AGGAAAGAAA GACTAATTTT ATCACAGACT 
AATATGCAGT TCCCTCCCTT CGCACCTCCA CCTACCAACG GCATCCCACA ACAAGCATGG 
GAGGAGAAAA AGACTGATGT GGAGAATCTA ATGTCCAAAG TTATGGAAAT TCAGAATCGC 
CGCCAAACAC TTCATCAGCT TCAAGAGGAA CTGAATTGGG AGAAAGAGAC GATTCAAGGT 
CTCAGTGAGA TGGATACAGG TGCTAAACAG AAACGCATTC AGCAAATTGA GTATAACGCA 
ACAATTTGTG CACAGGAGCG TGTACAGTTT CTTTGCGATG CCGTAGGAGC TCTGGAGCAA 
TGTCAGTCCT CTTTAATGCT TAAAATTGAG TCCTGGAGGT GGGAACAGCA TCGATCAACC 
ATTGGCATGC CCTTCAATGA CATCCTCGAC CATCTGCAGA CATGGAGTGA GCAGTTGCTC 
ATAGTGAATG GTAACCTGAG ACAGGAGCTC ATGCTGATGA AAGTGGACCA TGGAGATGCT 
GAACGGCTTC GAACTTTGGA GGAAAACCTG GCACGTCTAC TCAAGACTCT CATTCAGAAT 
TCATTGGTAG TAGAGAAGCA GCCTCCCCAG GTCATCAAAA CTCAGTCCAA GTTTTCCACC 
ACTGTACGCT ATCTGCTGGG AGACAAGATG GCCCCTGGAA AACCTGTCTT ATTAAAGGCT 
CAGATTATCA CCGAGGCACA AGCAAGAAAC CTGGGTCAAC AAAGTGTCAT TCCCAATGAA 
AATGTTGGAG AACTTCTTAA TAGTACGACG ATCTTGGAGC ACAACACCAC CAGCAAGAAC 
ACCTGTGCCA CCTTTAGAAA CATGTCCATA AGGAGGATCA AACGGGCTGA CAGGAAGGGC 
TCTGAATCAG TGACTGAGGA AAAGTTTGCA TTGTTGTTTA CCACAGATAT AACCATCACC 
GGCGGTGAGA GGCCATACAG CCTTCAGAGC ATCTCTCTTC CTGTGGTTGT AATTGTACAC 
GGTAGTCAGG AAATCAATGC CATGGCCACC ATCATATGGG ACTGCGCCTT CTCTGAGCCA 
AACAGGATAC CATTCCTTGT TCCTGAGCGT GTGTCCTGGC AGCAGATGTG TGGGGCTCTT 
AGCAGTAAGT TCATGTCTGA GGTCCAGACA ACCCGGGGCC TGGACCCATT AAACCTACGC 
TTTCTGGGCC AAAAGATCTT TGATCAACCT GATCACCCTG GAGATTTCGA AAACATGCTT 
GTTTCCTGGG CTCAATTCAA CAAGGAAGTT CTGCCTGGTC GAAACTTCAC CTTCTGGCAG 
TGGTTTGAAG GGGCAATAGA CCTAACTAAG AGATGCCTAC GAGACTATTG GACAGATGGA 
TTGATCTTCG GCTTTATTGG AAAACAGTAC ATCCACTGCA TGCTGCAGGA TAAAACCAAC 
GGCTTCTTCC TTCTGCGCTT CAGTGACTCA GAAATTGGTG GCATCACCAT TGCATATGTG 
GAACCCACTG AAAACGGAGG CAGGAGAGTC CAGAATATTC AGCCTTTCAC CAAAAAGGAT 
CTGGACTCAG CTGGCCTTGG CGATCGCATT CGGGACATTA GCTGCATCAG TCATGTATAT 
CCAGGCATTC CAAAGAATGA AGCATTTAAG AAATACTTTA CAGTGCCCTC CGCTCCTAAT 
GCTGATGGAT ACCTGCCTTT CAAGCTTACA ACAGTTGTCA ACCCAGGAGA CAATAGCACC 
TCCACTAACA ACATAACCTC TGAGAATATC TCTATGAATT TTATTTCACC ATCTACGTCT 
CAGGCATTTG GGCAAAACAT GAATCAGGAC ATATATAATC AACATTGTAC GCCTTCATAT 
AGTATGCCAG ATGACATCAT GCCTCCCCAA CCAATGTACC CGACAGACAT GCAGGTAAAC 
CCCCCTGACG AATTTTCAGA AATGGAGGAA TTTGAGGGAC TTCTGTCATC TATCTAA