map1lc3b cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	map1lc3b
Entrez Gene ID	322425
Full Name	microtubule-associated protein 1 light chain 3 beta
Synonyms	Map1lc3,wu:fb60g11,zgc:56434
General protein information	Preferred Names microtubule-associated protein 1 light chain 3 beta Names microtubule-associated proteins 1A/1B light chain 3B Lc3
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_199604.1	NP_955898.1	microtubule-associated proteins 1A/1B light chain 3B

Pathways from BioSystems

Homologies

Homo sapiens (human)	MAP1LC3B	NP_073729.1
Mus musculus (house mouse)	Map1lc3b	NP_080436.1
Danio rerio (zebrafish)	map1lc3b	NP_955898.1
Gallus gallus (chicken)	MAP1LC3B	NP_001026632.1
Xenopus tropicalis (tropical clawed frog)	map1lc3b	NP_989346.1
Macaca mulatta (Rhesus monkey)	LOC697790	XP_001086333.2
Canis lupus familiaris (dog)	MAP1LC3B	XP_536756.2
Bos taurus (cattle)	MAP1LC3B	NP_001001169.1
Rattus norvegicus (Norway rat)	Map1lc3b	NP_074058.2
Pan troglodytes (chimpanzee)	MAP1LC3B	NP_001233505.1
Macaca mulatta (Rhesus monkey)	MAP1LC3B	XP_002802632.1

Gene Ontology
Bibliography

Related articles in PubMed

A novel transgenic zebrafish line allows for in vivo quantification of autophagic activity in neurons.
Khuansuwan S, Barnhill LM, Cheng S, Bronstein JM
Autophagy15(8)1322-1332(2019 Aug)

Hepatotoxicity Induced by Isoniazid-Lipopolysaccharide through Endoplasmic Reticulum Stress, Autophagy, and Apoptosis Pathways in Zebrafish.
Zhang Y, Cen J, Jia Z, Hsiao CD, Xia Q, Wang X, Chen X, Wang R, Jiang Z, Zhang L, Liu K
Antimicrobial agents and chemotherapy63(5)(2019 05)

Hedgehog signaling regulates osteoblast differentiation in zebrafish larvae through modulation of autophagy.
Hu Z, Chen B, Zhao Q
Biology open8(5)(2019 May)

The selective autophagy receptors Optineurin and p62 are both required for zebrafish host resistance to mycobacterial infection.
Zhang R, Varela M, Vallentgoed W, Forn-Cuni G, van der Vaart M, Meijer AH
PLoS pathogens15(2)e1007329(2019 02)

Resveratrol-Induced Xenophagy Promotes Intracellular Bacteria Clearance in Intestinal Epithelial Cells and Macrophages.
Al Azzaz J, Rieu A, Aires V, Delmas D, Chluba J, Winckler P, Bringer MA, Lamarche J, Vervandier-Fasseur D, Dalle F, Lapaquette P, Guzzo J
Frontiers in immunology93149(2018)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following map1lc3b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the map1lc3b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa01204	NM_199604.1 Latest version!	Danio rerio microtubule-associated protein 1 light chain 3 beta (map1lc3b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

map1lc3b ( NM_199604.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_955898.1 Danio rerio microtubule-associated protein 1 light chain 3 beta (map1lc3b), mRNA.

Price & Availability↑

CloneID	ODa01204
Clone ID Related Accession (Same CDS sequence)	NM_199604.1
Accession Version	NM_199604.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 369bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573747200000
Organism	Danio rerio(zebrafish)
Product	microtubule-associated proteins 1A/1B light chain 3B
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC049313.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC049313.1, BC155206.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGCCTTCGG AAAAGACATT TAAACAAAGG AGGACATTTG AGCAGCGGGT GGAGGATGTA 
CGGCTGATCC GGGAACAGCA TCCAAACAAG ATCCCGGTCA TCATCGAGAG ATACAAGGGA 
GAGAAGCAAC TGCCGATTCT TGACAAAACT AAGTTTCTAG TTCCTGACCA CGTTAACATG 
AGCGAACTTA TTAAGATTAT CAGGCGACGC CTCCAACTCA ACTCCAACCA GGCTTTCTTC 
CTGCTGGTCA ACGGTCACAG CATGGTATCT GTGTCCACTG CCATTTCTGA GGTCTATGAA 
CGGGAAAGAG ACGAAGACGG CTTTCTGTAC ATGGTCTACG CTTCCCAGGA GACATTTGGA 
TTTCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_955898.1
CDS	175..543
Translation	MPSEKTFKQRRTFEQRVEDVRLIREQHPNKIPVIIERYKGEKQLPILDKTKFLVPDHVNMSELIKIIRRRLQLNSNQAFFLLVNGHSMVSVSTAISEVYERERDEDGFLYMVYASQETFGFQ

Target ORF information:

RefSeq Version	NM_199604.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio microtubule-associated protein 1 light chain 3 beta (map1lc3b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_199604.1

ORF Insert Sequence:

ATGCCTTCGG AAAAGACATT TAAACAAAGG AGGACATTTG AGCAGCGGGT GGAGGATGTA 
CGGCTGATCC GGGAACAGCA TCCAAACAAG ATCCCGGTCA TCATCGAGAG ATACAAGGGA 
GAGAAGCAAC TGCCGATTCT TGACAAAACT AAGTTTCTAG TTCCTGACCA CGTTAACATG 
AGCGAACTTA TTAAGATTAT CAGGCGACGC CTCCAACTCA ACTCCAACCA GGCTTTCTTC 
CTGCTGGTCA ACGGTCACAG CATGGTATCT GTGTCCACTG CCATTTCTGA GGTCTATGAA 
CGGGAAAGAG ACGAAGACGG CTTTCTGTAC ATGGTCTACG CTTCCCAGGA GACATTTGGA 
TTTCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A novel transgenic zebrafish line allows for in vivo quantification of autophagic activity in neurons.
Autophagy15(8)1322-1332(2019 Aug)
Khuansuwan S,Barnhill LM,Cheng S,Bronstein JM

Hepatotoxicity Induced by Isoniazid-Lipopolysaccharide through Endoplasmic Reticulum Stress, Autophagy, and Apoptosis Pathways in Zebrafish.
Antimicrobial agents and chemotherapy63(5)(2019 05)
Zhang Y,Cen J,Jia Z,Hsiao CD,Xia Q,Wang X,Chen X,Wang R,Jiang Z,Zhang L,Liu K

Hedgehog signaling regulates osteoblast differentiation in zebrafish larvae through modulation of autophagy.
Biology open8(5)(2019 May)
Hu Z,Chen B,Zhao Q

The selective autophagy receptors Optineurin and p62 are both required for zebrafish host resistance to mycobacterial infection.
PLoS pathogens15(2)e1007329(2019 02)
Zhang R,Varela M,Vallentgoed W,Forn-Cuni G,van der Vaart M,Meijer AH

Resveratrol-Induced Xenophagy Promotes Intracellular Bacteria Clearance in Intestinal Epithelial Cells and Macrophages.
Frontiers in immunology93149(2018)
Al Azzaz J,Rieu A,Aires V,Delmas D,Chluba J,Winckler P,Bringer MA,Lamarche J,Vervandier-Fasseur D,Dalle F,Lapaquette P,Guzzo J