ctsla cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	ctsla
Entrez Gene ID	321453
Full Name	cathepsin La
Synonyms	ctsl1a,hm:zeh1631,ik:tdsubc_2d2,ik:tdsubc_2f10,sb:cb143,wu:fb70e06,wu:fi15c08,xx:tdsubc_2d2,xx:tdsubc_2f10
General protein information	Preferred Names cathepsin La Names cathepsin L1 cathepsin L, 1 a cathepsin L, a tdsubc_2f10
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005165268.2	XP_005165325.1	cathepsin L1 isoform X1
XM_005165268.1	XP_005165325.1	cathepsin L1 isoform X1
XM_021476007.1	XP_021331682.1	cathepsin L1 isoform X2
NM_212584.1	NP_997749.1	cathepsin L1 precursor

Pathways from BioSystems

Homologies

Arabidopsis thaliana (thale cress)	AT5G43060	NP_568620.1
Bos taurus (cattle)	CTSV	NP_776457.1
Mus musculus (house mouse)	Ctsl	NP_034114.1
Caenorhabditis elegans (roundworm)	cpl-1	NP_001256718.1
Arabidopsis thaliana (thale cress)	AT3G19390	NP_566633.1
Xenopus tropicalis (tropical clawed frog)	ctsv	NP_001004869.1
Canis lupus familiaris (dog)	CTSL	NP_001239115.1
Oryza sativa (rice)	Os04g0670200	NP_001054211.2
Oryza sativa (rice)	Os04g0670500	NP_001054213.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011828	XP_001689282.1
Danio rerio (zebrafish)	ctsla	NP_997749.1
Arabidopsis thaliana (thale cress)	RD21	NP_564497.1
Pan troglodytes (chimpanzee)	CTSL2	XP_520130.2
Macaca mulatta (Rhesus monkey)	CTSL2	XP_002800251.1
Homo sapiens (human)	CTSV	NP_001324.2
Rattus norvegicus (Norway rat)	Ctsl1	NP_037288.1
Gallus gallus (chicken)	CTSL2	NP_001161481.1
Drosophila melanogaster (fruit fly)	Cp1	NP_523735.2
Arabidopsis thaliana (thale cress)	AT3G19400	NP_566634.2
Arabidopsis thaliana (thale cress)	AT3G43960	NP_566867.1
Canis lupus familiaris (dog)	LOC102156614	XP_005615836.1

Gene Ontology
Bibliography

Related articles in PubMed

Transcriptomic response and perturbation of toxicity pathways in zebrafish larvae after exposure to graphene quantum dots (GQDs).
Deng S, Jia PP, Zhang JH, Junaid M, Niu A, Ma YB, Fu A, Pei DS
Journal of hazardous materials357146-158(2018 09)

TGF-ß Regulates Cathepsin Activation during Normal and Pathogenic Development.
Flanagan-Steet H, Christian C, Lu PN, Aarnio-Peterson M, Sanman L, Archer-Hartmann S, Azadi P, Bogyo M, Steet RA
Cell reports22(11)2964-2977(2018 03)

Evolutionary and developmental analysis reveals KANK genes were co-opted for vertebrate vascular development.
Hensley MR, Cui Z, Chua RF, Simpson S, Shammas NL, Yang JY, Leung YF, Zhang G
Scientific reports627816(2016 06)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

Modulation of tissue repair by regeneration enhancer elements.
Kang J, Hu J, Karra R, Dickson AL, Tornini VA, Nachtrab G, Gemberling M, Goldman JA, Black BL, Poss KD
Nature532(7598)201-6(2016 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ctsla gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ctsla cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ODa01909	NM_212584.1 Latest version!	Danio rerio cathepsin La (ctsla), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ODa10665	XM_005165268.2 Latest version!	Danio rerio cathepsin La (ctsla), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ODa142564	XM_021476007.1 Latest version!	Danio rerio cathepsin La (ctsla), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
ODa10665	XM_005165268.1	Danio rerio cathepsin La (ctsla), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ctsla ( NM_212584.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_997749.1 Danio rerio cathepsin La (ctsla), mRNA.

Price & Availability↑

CloneID	ODa01909
Clone ID Related Accession (Same CDS sequence)	NM_212584.1
Accession Version	NM_212584.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550764800000
Organism	Danio rerio(zebrafish)
Product	cathepsin L1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC066490.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC066490.1, AF498292.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGAGGGTGT TCTTGGCTGC TTTTACCTTG TGCCTCAGCG CTGTGTTCGC TGCTCCTACT 
TTAGACCAGC AATTAAATGA TCATTGGGAT CAGTGGAAGA AATGGCACAG TAAAAAATAC 
CATGCAACAG AGGAAGGGTG GAGAAGAGTA ATCTGGGAGA AAAACTTGAA AAAGATTGAA 
ATGCACAATC TGGAGCACTC CATGGGCATA CACACCTACA GACTCGGAAT GAACCACTTT 
GGAGACATGA CTCACGAGGA GTTCAGACAG GTGATGAATG GTTTCAAACA CAAGAAAGAC 
AGACGATTCA GAGGATCCCT GTTCATGGAG CCCAACTTTA TTGAGGTCCC AAACAAGCTG 
GACTGGAGAG AGAAGGGATA TGTGACTCCT GTGAAAGATC AGGGTGAGTG TGGTTCTTGC 
TGGGCTTTTA GCACAACCGG AGCCCTGGAG GGTCAGATGT TCAGGAAGAC TGGAAAATTG 
GTGTCTTTGA GCGAGCAGAA CCTGGTGGAC TGCTCCCGTC CTGAAGGCAA TGAGGGCTGC 
AACGGAGGTC TCATGGACCA GGCCTTCCAG TACGTCAAGG ACCAGAATGG TCTCGACTCT 
GAGGAATCCT ACCCCTACCT GGGAACTGAC GATCAGCCCT GCCATTTTGA TCCCAAAAAC 
AGCGCAGCAA ATGACACCGG ATTCGTTGAC ATTCCCAGTG GAAAGGAGCG TGCTCTGATG 
AAAGCTATAG CTGCTGTGGG ACCTGTCTCT GTGGCTATTG ATGCTGGACA TGAGTCTTTC 
CAGTTTTACC AGTCAGGCAT CTACTATGAG AAGGAGTGCA GCAGTGAGGA GCTGGATCAT 
GGTGTTCTTG CGGTCGGTTA TGGTTTTGAG GGTGAGGATG TTGATGGCAA GAAGTATTGG 
ATTGTCAAAA ACAGCTGGAG TGAGAACTGG GGCGATAAAG GATACATCTA CATGGCCAAG 
GACAGACACA ATCACTGTGG TATTGCTACA GCAGCTAGCT ACCCTCTTGT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_997749.1
CDS	10..1023
Translation	MRVFLAAFTLCLSAVFAAPTLDQQLNDHWDQWKKWHSKKYHATEEGWRRVIWEKNLKKIEMHNLEHSMGIHTYRLGMNHFGDMTHEEFRQVMNGFKHKKDRRFRGSLFMEPNFIEVPNKLDWREKGYVTPVKDQGECGSCWAFSTTGALEGQMFRKTGKLVSLSEQNLVDCSRPEGNEGCNGGLMDQAFQYVKDQNGLDSEESYPYLGTDDQPCHFDPKNSAANDTGFVDIPSGKERALMKAIAAVGPVSVAIDAGHESFQFYQSGIYYEKECSSEELDHGVLAVGYGFEGEDVDGKKYWIVKNSWSENWGDKGYIYMAKDRHNHCGIATAASYPLV

Target ORF information:

RefSeq Version	NM_212584.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio cathepsin La (ctsla), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_212584.1

ORF Insert Sequence:

ATGAGGGTGT TCTTGGCTGC TTTTACCTTG TGCCTCAGCG CTGTGTTCGC TGCTCCTACT 
TTAGACCAGC AATTAAATGA TCATTGGGAT CAGTGGAAGA AATGGCACAG TAAAAAATAC 
CATGCAACAG AGGAAGGGTG GAGAAGAGTA ATCTGGGAGA AAAACTTGAA AAAGATTGAA 
ATGCACAATC TGGAGCACTC CATGGGCATA CACACCTACA GACTCGGAAT GAACCACTTT 
GGAGACATGA CTCACGAGGA GTTCAGACAG GTGATGAATG GTTTCAAACA CAAGAAAGAC 
AGACGATTCA GAGGATCCCT GTTCATGGAG CCCAACTTTA TTGAGGTCCC AAACAAGCTG 
GACTGGAGAG AGAAGGGATA TGTGACTCCT GTGAAAGATC AGGGTGAGTG TGGTTCTTGC 
TGGGCTTTTA GCACAACCGG AGCCCTGGAG GGTCAGATGT TCAGGAAGAC TGGAAAATTG 
GTGTCTTTGA GCGAGCAGAA CCTGGTGGAC TGCTCCCGTC CTGAAGGCAA TGAGGGCTGC 
AACGGAGGTC TCATGGACCA GGCCTTCCAG TACGTCAAGG ACCAGAATGG TCTCGACTCT 
GAGGAATCCT ACCCCTACCT GGGAACTGAC GATCAGCCCT GCCATTTTGA TCCCAAAAAC 
AGCGCAGCAA ATGACACCGG ATTCGTTGAC ATTCCCAGTG GAAAGGAGCG TGCTCTGATG 
AAAGCTATAG CTGCTGTGGG ACCTGTCTCT GTGGCTATTG ATGCTGGACA TGAGTCTTTC 
CAGTTTTACC AGTCAGGCAT CTACTATGAG AAGGAGTGCA GCAGTGAGGA GCTGGATCAT 
GGTGTTCTTG CGGTCGGTTA TGGTTTTGAG GGTGAGGATG TTGATGGCAA GAAGTATTGG 
ATTGTCAAAA ACAGCTGGAG TGAGAACTGG GGCGATAAAG GATACATCTA CATGGCCAAG 
GACAGACACA ATCACTGTGG TATTGCTACA GCAGCTAGCT ACCCTCTTGT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ctsla ( XM_005165268.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_005165325.1 Danio rerio cathepsin La (ctsla), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa10665
Clone ID Related Accession (Same CDS sequence)	XM_005165268.2 , XM_005165268.1
Accession Version	XM_005165268.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1092bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1497369600000
Organism	Danio rerio(zebrafish)
Product	cathepsin L1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007116.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XM_005165268.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGCTATA AAACTTGTGG CCCCTCACAG CGACTCACAA TATTTTCTCC TGGATTCGGG 
ACAACGCGTG TTTTCATCAT GAGGGTGTTC TTGGCTGCTT TTACCTTGTG CCTCAGCGCT 
GTGTTCGCTG CTCCTACTTT GGACCAGCAA TTAAATGATC ATTGGGATCA GTGGAAGAAA 
TGGCACAGTA AAAAATACCA TGCAACAGAG GAAGGGTGGA GAAGGATAAT CTGGGAGAAA 
AACTTGAAAA AGATTGAAAT GCACAATCTG GAGCACTCCA TGGGCATACA CACCTACAGA 
CTCGGAATGA ACCACTTTGG AGACATGACT CACGAGGAGT TCAGACAGGT GATGAATGGT 
TTCAAACACA AGAAAGACAG ACGATTCAGA GGATCCCTGT TCATGGAGCC CAACTTCATT 
GAGGTCCCAA ACAAGCTGGA CTGGAGAGAG AAGGGATATG TGACTCCTGT GAAAGATCAG 
GGTGAGTGTG GTTCTTGCTG GGCTTTTAGC ACAACCGGAG CCCTGGAGGG TCAGATGTTC 
AGGAAGACTG GAAAATTGGT GTCTTTGAGC GAGCAGAACC TGGTGGACTG CTCCCGTCCT 
GAAGGCAATG AGGGCTGCAA CGGAGGTCTC ATGGACCAGG CCTTCCAGTA CGTCAAGGAC 
CAGAATGGTC TCGACTCTGA GGAATCCTAC CCCTACCTGG GAACTGACGA TCAGCCCTGC 
CATTTTGATC CCAAAAACAG CGCAGCAAAT GACACCGGAT TCGTTGACAT TCCCAGTGGA 
AAGGAGCGTG CTCTGATGAA AGCTATAGCT GCTGTGGGAC CTGTCTCTGT GGCTATTGAT 
GCTGGACATG AGTCTTTCCA GTTTTACCAG TCAGGCATCT ACTATGAGAA GGAGTGCAGC 
AGTGAGGAGC TGGATCATGG TGTTCTTGCG GTCGGTTATG GTTTTGAGGG TGAGGATGTT 
GATGGCAAGA AGTATTGGAT TGTCAAAAAC AGCTGGAGTG AGAACTGGGG CGATAAAGGA 
TACATCTACA TGGCCAAGGA CAGACACAAT CACTGTGGTA TTGCTACAGC AGCTAGCTAC 
CCTCTTGTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005165325.1
CDS	70..1161
Translation	MRYKTCGPSQRLTIFSPGFGTTRVFIMRVFLAAFTLCLSAVFAAPTLDQQLNDHWDQWKKWHSKKYHATEEGWRRIIWEKNLKKIEMHNLEHSMGIHTYRLGMNHFGDMTHEEFRQVMNGFKHKKDRRFRGSLFMEPNFIEVPNKLDWREKGYVTPVKDQGECGSCWAFSTTGALEGQMFRKTGKLVSLSEQNLVDCSRPEGNEGCNGGLMDQAFQYVKDQNGLDSEESYPYLGTDDQPCHFDPKNSAANDTGFVDIPSGKERALMKAIAAVGPVSVAIDAGHESFQFYQSGIYYEKECSSEELDHGVLAVGYGFEGEDVDGKKYWIVKNSWSENWGDKGYIYMAKDRHNHCGIATAASYPLV

Target ORF information:

RefSeq Version	XM_005165268.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio cathepsin La (ctsla), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005165268.2

ORF Insert Sequence:

ATGCGCTATA AAACTTGTGG CCCCTCACAG CGACTCACAA TATTTTCTCC TGGATTCGGG 
ACAACGCGTG TTTTCATCAT GAGGGTGTTC TTGGCTGCTT TTACCTTGTG CCTCAGCGCT 
GTGTTCGCTG CTCCTACTTT GGACCAGCAA TTAAATGATC ATTGGGATCA GTGGAAGAAA 
TGGCACAGTA AAAAATACCA TGCAACAGAG GAAGGGTGGA GAAGGATAAT CTGGGAGAAA 
AACTTGAAAA AGATTGAAAT GCACAATCTG GAGCACTCCA TGGGCATACA CACCTACAGA 
CTCGGAATGA ACCACTTTGG AGACATGACT CACGAGGAGT TCAGACAGGT GATGAATGGT 
TTCAAACACA AGAAAGACAG ACGATTCAGA GGATCCCTGT TCATGGAGCC CAACTTCATT 
GAGGTCCCAA ACAAGCTGGA CTGGAGAGAG AAGGGATATG TGACTCCTGT GAAAGATCAG 
GGTGAGTGTG GTTCTTGCTG GGCTTTTAGC ACAACCGGAG CCCTGGAGGG TCAGATGTTC 
AGGAAGACTG GAAAATTGGT GTCTTTGAGC GAGCAGAACC TGGTGGACTG CTCCCGTCCT 
GAAGGCAATG AGGGCTGCAA CGGAGGTCTC ATGGACCAGG CCTTCCAGTA CGTCAAGGAC 
CAGAATGGTC TCGACTCTGA GGAATCCTAC CCCTACCTGG GAACTGACGA TCAGCCCTGC 
CATTTTGATC CCAAAAACAG CGCAGCAAAT GACACCGGAT TCGTTGACAT TCCCAGTGGA 
AAGGAGCGTG CTCTGATGAA AGCTATAGCT GCTGTGGGAC CTGTCTCTGT GGCTATTGAT 
GCTGGACATG AGTCTTTCCA GTTTTACCAG TCAGGCATCT ACTATGAGAA GGAGTGCAGC 
AGTGAGGAGC TGGATCATGG TGTTCTTGCG GTCGGTTATG GTTTTGAGGG TGAGGATGTT 
GATGGCAAGA AGTATTGGAT TGTCAAAAAC AGCTGGAGTG AGAACTGGGG CGATAAAGGA 
TACATCTACA TGGCCAAGGA CAGACACAAT CACTGTGGTA TTGCTACAGC AGCTAGCTAC 
CCTCTTGTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ctsla ( XM_005165268.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_005165325.1 Danio rerio cathepsin La (ctsla), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa10665
Clone ID Related Accession (Same CDS sequence)	XM_005165268.2 , XM_005165268.1
Accession Version	XM_005165268.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1092bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466611200000
Organism	Danio rerio(Zebrafish)
Product	cathepsin L1 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007116.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGCTATA AAACTTGTGG CCCCTCACAG CGACTCACAA TATTTTCTCC TGGATTCGGG 
ACAACGCGTG TTTTCATCAT GAGGGTGTTC TTGGCTGCTT TTACCTTGTG CCTCAGCGCT 
GTGTTCGCTG CTCCTACTTT GGACCAGCAA TTAAATGATC ATTGGGATCA GTGGAAGAAA 
TGGCACAGTA AAAAATACCA TGCAACAGAG GAAGGGTGGA GAAGGATAAT CTGGGAGAAA 
AACTTGAAAA AGATTGAAAT GCACAATCTG GAGCACTCCA TGGGCATACA CACCTACAGA 
CTCGGAATGA ACCACTTTGG AGACATGACT CACGAGGAGT TCAGACAGGT GATGAATGGT 
TTCAAACACA AGAAAGACAG ACGATTCAGA GGATCCCTGT TCATGGAGCC CAACTTCATT 
GAGGTCCCAA ACAAGCTGGA CTGGAGAGAG AAGGGATATG TGACTCCTGT GAAAGATCAG 
GGTGAGTGTG GTTCTTGCTG GGCTTTTAGC ACAACCGGAG CCCTGGAGGG TCAGATGTTC 
AGGAAGACTG GAAAATTGGT GTCTTTGAGC GAGCAGAACC TGGTGGACTG CTCCCGTCCT 
GAAGGCAATG AGGGCTGCAA CGGAGGTCTC ATGGACCAGG CCTTCCAGTA CGTCAAGGAC 
CAGAATGGTC TCGACTCTGA GGAATCCTAC CCCTACCTGG GAACTGACGA TCAGCCCTGC 
CATTTTGATC CCAAAAACAG CGCAGCAAAT GACACCGGAT TCGTTGACAT TCCCAGTGGA 
AAGGAGCGTG CTCTGATGAA AGCTATAGCT GCTGTGGGAC CTGTCTCTGT GGCTATTGAT 
GCTGGACATG AGTCTTTCCA GTTTTACCAG TCAGGCATCT ACTATGAGAA GGAGTGCAGC 
AGTGAGGAGC TGGATCATGG TGTTCTTGCG GTCGGTTATG GTTTTGAGGG TGAGGATGTT 
GATGGCAAGA AGTATTGGAT TGTCAAAAAC AGCTGGAGTG AGAACTGGGG CGATAAAGGA 
TACATCTACA TGGCCAAGGA CAGACACAAT CACTGTGGTA TTGCTACAGC AGCTAGCTAC 
CCTCTTGTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005165325.1
CDS	45..1136
Translation	MRYKTCGPSQRLTIFSPGFGTTRVFIMRVFLAAFTLCLSAVFAAPTLDQQLNDHWDQWKKWHSKKYHATEEGWRRIIWEKNLKKIEMHNLEHSMGIHTYRLGMNHFGDMTHEEFRQVMNGFKHKKDRRFRGSLFMEPNFIEVPNKLDWREKGYVTPVKDQGECGSCWAFSTTGALEGQMFRKTGKLVSLSEQNLVDCSRPEGNEGCNGGLMDQAFQYVKDQNGLDSEESYPYLGTDDQPCHFDPKNSAANDTGFVDIPSGKERALMKAIAAVGPVSVAIDAGHESFQFYQSGIYYEKECSSEELDHGVLAVGYGFEGEDVDGKKYWIVKNSWSENWGDKGYIYMAKDRHNHCGIATAASYPLV

Target ORF information:

RefSeq Version	XM_005165268.1
Organism	Danio rerio(Zebrafish)
Definition	Danio rerio cathepsin La (ctsla), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005165268.1

ORF Insert Sequence:

ATGCGCTATA AAACTTGTGG CCCCTCACAG CGACTCACAA TATTTTCTCC TGGATTCGGG 
ACAACGCGTG TTTTCATCAT GAGGGTGTTC TTGGCTGCTT TTACCTTGTG CCTCAGCGCT 
GTGTTCGCTG CTCCTACTTT GGACCAGCAA TTAAATGATC ATTGGGATCA GTGGAAGAAA 
TGGCACAGTA AAAAATACCA TGCAACAGAG GAAGGGTGGA GAAGGATAAT CTGGGAGAAA 
AACTTGAAAA AGATTGAAAT GCACAATCTG GAGCACTCCA TGGGCATACA CACCTACAGA 
CTCGGAATGA ACCACTTTGG AGACATGACT CACGAGGAGT TCAGACAGGT GATGAATGGT 
TTCAAACACA AGAAAGACAG ACGATTCAGA GGATCCCTGT TCATGGAGCC CAACTTCATT 
GAGGTCCCAA ACAAGCTGGA CTGGAGAGAG AAGGGATATG TGACTCCTGT GAAAGATCAG 
GGTGAGTGTG GTTCTTGCTG GGCTTTTAGC ACAACCGGAG CCCTGGAGGG TCAGATGTTC 
AGGAAGACTG GAAAATTGGT GTCTTTGAGC GAGCAGAACC TGGTGGACTG CTCCCGTCCT 
GAAGGCAATG AGGGCTGCAA CGGAGGTCTC ATGGACCAGG CCTTCCAGTA CGTCAAGGAC 
CAGAATGGTC TCGACTCTGA GGAATCCTAC CCCTACCTGG GAACTGACGA TCAGCCCTGC 
CATTTTGATC CCAAAAACAG CGCAGCAAAT GACACCGGAT TCGTTGACAT TCCCAGTGGA 
AAGGAGCGTG CTCTGATGAA AGCTATAGCT GCTGTGGGAC CTGTCTCTGT GGCTATTGAT 
GCTGGACATG AGTCTTTCCA GTTTTACCAG TCAGGCATCT ACTATGAGAA GGAGTGCAGC 
AGTGAGGAGC TGGATCATGG TGTTCTTGCG GTCGGTTATG GTTTTGAGGG TGAGGATGTT 
GATGGCAAGA AGTATTGGAT TGTCAAAAAC AGCTGGAGTG AGAACTGGGG CGATAAAGGA 
TACATCTACA TGGCCAAGGA CAGACACAAT CACTGTGGTA TTGCTACAGC AGCTAGCTAC 
CCTCTTGTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ctsla ( XM_021476007.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_021331682.1 Danio rerio cathepsin La (ctsla), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ODa142564
Clone ID Related Accession (Same CDS sequence)	XM_021476007.1
Accession Version	XM_021476007.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1497369600000
Organism	Danio rerio(zebrafish)
Product	cathepsin L1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007116.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGGTGT TCTTGGCTGC TTTTACCTTG TGCCTCAGCG CTGTGTTCGC TGCTCCTACT 
TTGGACCAGC AATTAAATGA TCATTGGGAT CAGTGGAAGA AATGGCACAG TAAAAAATAC 
CATGCAACAG AGGAAGGGTG GAGAAGGATA ATCTGGGAGA AAAACTTGAA AAAGATTGAA 
ATGCACAATC TGGAGCACTC CATGGGCATA CACACCTACA GACTCGGAAT GAACCACTTT 
GGAGACATGA CTCACGAGGA GTTCAGACAG GTGATGAATG GTTTCAAACA CAAGAAAGAC 
AGACGATTCA GAGGATCCCT GTTCATGGAG CCCAACTTCA TTGAGGTCCC AAACAAGCTG 
GACTGGAGAG AGAAGGGATA TGTGACTCCT GTGAAAGATC AGGGTGAGTG TGGTTCTTGC 
TGGGCTTTTA GCACAACCGG AGCCCTGGAG GGTCAGATGT TCAGGAAGAC TGGAAAATTG 
GTGTCTTTGA GCGAGCAGAA CCTGGTGGAC TGCTCCCGTC CTGAAGGCAA TGAGGGCTGC 
AACGGAGGTC TCATGGACCA GGCCTTCCAG TACGTCAAGG ACCAGAATGG TCTCGACTCT 
GAGGAATCCT ACCCCTACCT GGGAACTGAC GATCAGCCCT GCCATTTTGA TCCCAAAAAC 
AGCGCAGCAA ATGACACCGG ATTCGTTGAC ATTCCCAGTG GAAAGGAGCG TGCTCTGATG 
AAAGCTATAG CTGCTGTGGG ACCTGTCTCT GTGGCTATTG ATGCTGGACA TGAGTCTTTC 
CAGTTTTACC AGTCAGGCAT CTACTATGAG AAGGAGTGCA GCAGTGAGGA GCTGGATCAT 
GGTGTTCTTG CGGTCGGTTA TGGTTTTGAG GGTGAGGATG TTGATGGCAA GAAGTATTGG 
ATTGTCAAAA ACAGCTGGAG TGAGAACTGG GGCGATAAAG GATACATCTA CATGGCCAAG 
GACAGACACA ATCACTGTGG TATTGCTACA GCAGCTAGCT ACCCTCTTGT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_021331682.1
CDS	357..1370
Translation	MRVFLAAFTLCLSAVFAAPTLDQQLNDHWDQWKKWHSKKYHATEEGWRRIIWEKNLKKIEMHNLEHSMGIHTYRLGMNHFGDMTHEEFRQVMNGFKHKKDRRFRGSLFMEPNFIEVPNKLDWREKGYVTPVKDQGECGSCWAFSTTGALEGQMFRKTGKLVSLSEQNLVDCSRPEGNEGCNGGLMDQAFQYVKDQNGLDSEESYPYLGTDDQPCHFDPKNSAANDTGFVDIPSGKERALMKAIAAVGPVSVAIDAGHESFQFYQSGIYYEKECSSEELDHGVLAVGYGFEGEDVDGKKYWIVKNSWSENWGDKGYIYMAKDRHNHCGIATAASYPLV

Target ORF information:

RefSeq Version	XM_021476007.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio cathepsin La (ctsla), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_021476007.1

ORF Insert Sequence:

ATGAGGGTGT TCTTGGCTGC TTTTACCTTG TGCCTCAGCG CTGTGTTCGC TGCTCCTACT 
TTGGACCAGC AATTAAATGA TCATTGGGAT CAGTGGAAGA AATGGCACAG TAAAAAATAC 
CATGCAACAG AGGAAGGGTG GAGAAGGATA ATCTGGGAGA AAAACTTGAA AAAGATTGAA 
ATGCACAATC TGGAGCACTC CATGGGCATA CACACCTACA GACTCGGAAT GAACCACTTT 
GGAGACATGA CTCACGAGGA GTTCAGACAG GTGATGAATG GTTTCAAACA CAAGAAAGAC 
AGACGATTCA GAGGATCCCT GTTCATGGAG CCCAACTTCA TTGAGGTCCC AAACAAGCTG 
GACTGGAGAG AGAAGGGATA TGTGACTCCT GTGAAAGATC AGGGTGAGTG TGGTTCTTGC 
TGGGCTTTTA GCACAACCGG AGCCCTGGAG GGTCAGATGT TCAGGAAGAC TGGAAAATTG 
GTGTCTTTGA GCGAGCAGAA CCTGGTGGAC TGCTCCCGTC CTGAAGGCAA TGAGGGCTGC 
AACGGAGGTC TCATGGACCA GGCCTTCCAG TACGTCAAGG ACCAGAATGG TCTCGACTCT 
GAGGAATCCT ACCCCTACCT GGGAACTGAC GATCAGCCCT GCCATTTTGA TCCCAAAAAC 
AGCGCAGCAA ATGACACCGG ATTCGTTGAC ATTCCCAGTG GAAAGGAGCG TGCTCTGATG 
AAAGCTATAG CTGCTGTGGG ACCTGTCTCT GTGGCTATTG ATGCTGGACA TGAGTCTTTC 
CAGTTTTACC AGTCAGGCAT CTACTATGAG AAGGAGTGCA GCAGTGAGGA GCTGGATCAT 
GGTGTTCTTG CGGTCGGTTA TGGTTTTGAG GGTGAGGATG TTGATGGCAA GAAGTATTGG 
ATTGTCAAAA ACAGCTGGAG TGAGAACTGG GGCGATAAAG GATACATCTA CATGGCCAAG 
GACAGACACA ATCACTGTGG TATTGCTACA GCAGCTAGCT ACCCTCTTGT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Transcriptomic response and perturbation of toxicity pathways in zebrafish larvae after exposure to graphene quantum dots (GQDs).
Journal of hazardous materials357146-158(2018 09)
Deng S,Jia PP,Zhang JH,Junaid M,Niu A,Ma YB,Fu A,Pei DS

TGF-ß Regulates Cathepsin Activation during Normal and Pathogenic Development.
Cell reports22(11)2964-2977(2018 03)
Flanagan-Steet H,Christian C,Lu PN,Aarnio-Peterson M,Sanman L,Archer-Hartmann S,Azadi P,Bogyo M,Steet RA

Evolutionary and developmental analysis reveals KANK genes were co-opted for vertebrate vascular development.
Scientific reports627816(2016 06)
Hensley MR,Cui Z,Chua RF,Simpson S,Shammas NL,Yang JY,Leung YF,Zhang G

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

Modulation of tissue repair by regeneration enhancer elements.
Nature532(7598)201-6(2016 Apr)
Kang J,Hu J,Karra R,Dickson AL,Tornini VA,Nachtrab G,Gemberling M,Goldman JA,Black BL,Poss KD

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ctsla cDNA ORF clone, Danio rerio(zebrafish)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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