stat1a cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	stat1a
Entrez Gene ID	30768
Full Name	signal transducer and activator of transcription 1a
Synonyms	stat1
General protein information	Preferred Names signal transducer and activator of transcription 1a Names signal transducer and activator of transcription 1-alpha/beta signal transducer and activator of transcription 1, 91kDa signal transduction and activation of transcription 1 signal transduction and activation of transcription 1a
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_131480.1	NP_571555.1	signal transducer and activator of transcription 1-alpha/beta

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	LOC488449	XP_848353.1
Bos taurus (cattle)	STAT1	NP_001071368.1
Rattus norvegicus (Norway rat)	Stat1	NP_116001.2
Gallus gallus (chicken)	STAT1	NP_001012932.1
Pan troglodytes (chimpanzee)	STAT1	XP_003309418.1
Mus musculus (house mouse)	Stat1	NP_001192242.1
Homo sapiens (human)	STAT1	NP_009330.1
Macaca mulatta (Rhesus monkey)	STAT1	XP_002799062.1
Danio rerio (zebrafish)	stat1a	NP_571555.1
Xenopus tropicalis (tropical clawed frog)	stat1	NP_001072935.1

Gene Ontology
Bibliography

Related articles in PubMed

Mutation of
Gao X, Yuan YY, Lin QF, Xu JC, Wang WQ, Qiao YH, Kang DY, Bai D, Xin F, Huang SS, Qiu SW, Guan LP, Su Y, Wang GJ, Han MY, Jiang Y, Liu HK, Dai P
Journal of medical genetics55(5)298-306(2018 05)

MicroRNA-223 Suppresses the Canonical NF-κB Pathway in Basal Keratinocytes to Dampen Neutrophilic Inflammation.
Zhou W, Pal AS, Hsu AY, Gurol T, Zhu X, Wirbisky-Hershberger SE, Freeman JL, Kasinski AL, Deng Q
Cell reports22(7)1810-1823(2018 02)

Irf8 regulates the progression of myeloproliferative neoplasm-like syndrome via Mertk signaling in zebrafish.
Zhao F, Shi Y, Huang Y, Zhan Y, Zhou L, Li Y, Wan Y, Li H, Huang H, Ruan H, Luo L, Li L
Leukemia32(1)149-158(2018 01)

Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling.
Chernyavskaya Y, Mudbhary R, Zhang C, Tokarz D, Jacob V, Gopinath S, Sun X, Wang S, Magnani E, Madakashira BP, Yoder JA, Hoshida Y, Sadler KC
Development (Cambridge, England)144(16)2925-2939(2017 08)

Díaz-Pascual F, Ortíz-Severín J, Varas MA, Allende ML, Chávez FP
Frontiers in cellular and infection microbiology7334(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following stat1a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the stat1a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa02593	NM_131480.1 Latest version!	Danio rerio signal transducer and activator of transcription 1a (stat1a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

stat1a ( NM_131480.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_571555.1 Danio rerio signal transducer and activator of transcription 1a (stat1a), mRNA.

Price & Availability↑

CloneID	ODa02593
Clone ID Related Accession (Same CDS sequence)	NM_131480.1
Accession Version	NM_131480.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2250bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1548432000000
Organism	Danio rerio(zebrafish)
Product	signal transducer and activator of transcription 1-alpha/beta
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ005692.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ005692.1, BC060933.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGACTCAGT GGTTGGAGCT TCAGCAGCTG GATCCAAAGT TTTTGGAGCA GGTGGACCAG 
TTGTACGACG ACAACTTTCC CATGGCCATC CGACAATATC TCAGCAGCTG GATAGAAAGC 
CACGACTGGG ACCATGTCGC AAATGTGGAG AACGAGTCTC TGGCCACGGT GAGGTTTCAT 
GATCTTTTGA CTCAGCTGGA TCACCAACAC AGTCGCTTCG TGATGGAGAA AGACTTCCTA 
AACCAACACA ACATCCGCAA GTTCAAGAGG AACTTGCAGA ACCTCTTCCA AGACAATCCT 
GTTTCAATGG CGATGATCAT CAGCAGAAAC CTTCGCGAGG AAAGAAAGAT TATAGCCATT 
GCTGGAATGT CAGAGAGTCC AACACCGAAC CCCACACAGG ACATGATTGT GGAGAAAAAT 
CGTGAAATGG ACGCAAGGGT GAAAGACATA AAGAATAAAG TGCAGGACGC TGAGCAAACC 
ATTAAAAATC TGGAAGATTT GCAAGATGAA TACGACTTCA AGAATAAAAC TTACCAAAGC 
AGAGACGAAC TCAATGGCAC CATTTCAAAG GAGGACCTGA ACCGCGAGAA ACTGATGATC 
CACGCCATGT TTGTAAAACT CAATGATAAG AGAATAATGG CGATTAGTCA GATGTCCGAG 
GTGTTGAACC TGGTGGAACC GGTGATCTGT GAGCTGATCT CGACAGAACT GGTCGAATGG 
AAACGTCGTC AACAGATGGC TTGCATCGGC GGGCTAACTA ACGTCTGCCT GGATCAGTTG 
CAGAACTGGT TTACTTCTCT TGGAGAGTCT CTGCTTCAGA GCAGACAGCA GCTCAAGAAA 
CTCCTGGAGC TCGAGCAGAA GTTGTCATAC AGCACAGATC CCATCACCTG CAGCAAAATC 
TCTCTGGAAG AAAGGATCAT GTCAAACCTC AAAAATCTTG TCACAAACTC TTTGGTAGTG 
GAGAGACAGC CATGCATGCC GACCCAACTG CAGAGACCTT TAGTGCTGAA GACAGGAGTT 
CTGTTCACCC TCAAATTACG GCTGCTCGTA AAAATTCCGG AATTTAACCA CACTGTTCGG 
GTGAAGGTGC AATTTGATAA GGATATCGTT GAAAAACGAA AAGGGTTTCG TATGTTCAAC 
ATCTTGGGAA CATCCATGAA GGTGATGAAC ATGGAGGAGT CCAATGGAAT GGCAGCAGAA 
TTTCGTCATC TGCAATTGAA AGAGAGGAAA GTTACTGGAA ACAGAACCAG TGAGGGTCCG 
CTGATTGTCA CAGAGGAGCT CCACTCCATC ACCTTTGAGG CTGAGCTTTG CTGGTCTGGG 
TTGGTCATTA ACTTTGAGAC AACATCTCTG CCCATAGTCG TGATCTCCAA CGTCAGTCAG 
CTGCCCAGTG GATGGGCGTC CATTATGTGG TACAACATGC TGATCTCTGA ACCAAAGAAC 
CTGTCCTTTT TCGTGACTCC TCCACCGGCC ACATGGGGTC AGCTACAGGA AGTGCTGAGC 
TGGCAGTTTT CCTCCATCAC CAAACGAGGC CTTAATCCTG AACAGTTAAG CATGCTGGGA 
AATAAACTGC TGGGTCCTAA AGCGGCATCG GATCCTGAAG CTCAGATTCC CTGGAACCGA 
TTCTGTAAGT CTGGCAGTGA AAAGAACTTT ACCTTTTGGC TGTGGATTGA AGCAGTTCTT 
GACCTGATAA AGAGACATTT GCTGAGCCTG TGGGATGATG GGTGCATCAT GGGATTTGTG 
ACCAAAGATC GAACTAAATC TCTGCTCAAC AACAAAGCTC CAGGGACGTT TCTGCTGCGC 
TTCAGTGAAA GCAACCGTGA CGGAGCCATT ACGTTCAGCT GGGTTGAACA CGATGCAAAT 
GAGGATCCAC AGATTCGCTC CGTGGAGCCG TACACAAAGA AGGAGCTCTC CGCTGTTTCA 
CTTCCTGACA TCATTCGAAA CTACCGCGTA ATGGCCGCCG ACAACGTTCC CGAAAACCCT 
CTGCGCTTCC TGTATCCTCA GATTCCCAAA GACGATGCCT TCAAGAAATA CTACACCAAG 
CCCACTGACA AGCAAGAACC AATGGATGTT GATAAGAAGG CAGACGAGGG ATACATTAGC 
ACCACTCTCA TCTCCATCTC TGAAATGAAA CCACAAGAAT ATAACGAGAA CCTCATGCCA 
ATGTCACCTG AGGTCTACGG CGAGCTGGAG CGCATGAATC GATTCGATAC TGTACAATTG 
GAGCCAGCAG ACTTGATGAC AATGACATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_571555.1
CDS	96..2345
Translation	MTQWLELQQLDPKFLEQVDQLYDDNFPMAIRQYLSSWIESHDWDHVANVENESLATVRFHDLLTQLDHQHSRFVMEKDFLNQHNIRKFKRNLQNLFQDNPVSMAMIISRNLREERKIIAIAGMSESPTPNPTQDMIVEKNREMDARVKDIKNKVQDAEQTIKNLEDLQDEYDFKNKTYQSRDELNGTISKEDLNREKLMIHAMFVKLNDKRIMAISQMSEVLNLVEPVICELISTELVEWKRRQQMACIGGLTNVCLDQLQNWFTSLGESLLQSRQQLKKLLELEQKLSYSTDPITCSKISLEERIMSNLKNLVTNSLVVERQPCMPTQLQRPLVLKTGVLFTLKLRLLVKIPEFNHTVRVKVQFDKDIVEKRKGFRMFNILGTSMKVMNMEESNGMAAEFRHLQLKERKVTGNRTSEGPLIVTEELHSITFEAELCWSGLVINFETTSLPIVVISNVSQLPSGWASIMWYNMLISEPKNLSFFVTPPPATWGQLQEVLSWQFSSITKRGLNPEQLSMLGNKLLGPKAASDPEAQIPWNRFCKSGSEKNFTFWLWIEAVLDLIKRHLLSLWDDGCIMGFVTKDRTKSLLNNKAPGTFLLRFSESNRDGAITFSWVEHDANEDPQIRSVEPYTKKELSAVSLPDIIRNYRVMAADNVPENPLRFLYPQIPKDDAFKKYYTKPTDKQEPMDVDKKADEGYISTTLISISEMKPQEYNENLMPMSPEVYGELERMNRFDTVQLEPADLMTMT

Target ORF information:

RefSeq Version	NM_131480.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio signal transducer and activator of transcription 1a (stat1a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_131480.1

ORF Insert Sequence:

ATGACTCAGT GGTTGGAGCT TCAGCAGCTG GATCCAAAGT TTTTGGAGCA GGTGGACCAG 
TTGTACGACG ACAACTTTCC CATGGCCATC CGACAATATC TCAGCAGCTG GATAGAAAGC 
CACGACTGGG ACCATGTCGC AAATGTGGAG AACGAGTCTC TGGCCACGGT GAGGTTTCAT 
GATCTTTTGA CTCAGCTGGA TCACCAACAC AGTCGCTTCG TGATGGAGAA AGACTTCCTA 
AACCAACACA ACATCCGCAA GTTCAAGAGG AACTTGCAGA ACCTCTTCCA AGACAATCCT 
GTTTCAATGG CGATGATCAT CAGCAGAAAC CTTCGCGAGG AAAGAAAGAT TATAGCCATT 
GCTGGAATGT CAGAGAGTCC AACACCGAAC CCCACACAGG ACATGATTGT GGAGAAAAAT 
CGTGAAATGG ACGCAAGGGT GAAAGACATA AAGAATAAAG TGCAGGACGC TGAGCAAACC 
ATTAAAAATC TGGAAGATTT GCAAGATGAA TACGACTTCA AGAATAAAAC TTACCAAAGC 
AGAGACGAAC TCAATGGCAC CATTTCAAAG GAGGACCTGA ACCGCGAGAA ACTGATGATC 
CACGCCATGT TTGTAAAACT CAATGATAAG AGAATAATGG CGATTAGTCA GATGTCCGAG 
GTGTTGAACC TGGTGGAACC GGTGATCTGT GAGCTGATCT CGACAGAACT GGTCGAATGG 
AAACGTCGTC AACAGATGGC TTGCATCGGC GGGCTAACTA ACGTCTGCCT GGATCAGTTG 
CAGAACTGGT TTACTTCTCT TGGAGAGTCT CTGCTTCAGA GCAGACAGCA GCTCAAGAAA 
CTCCTGGAGC TCGAGCAGAA GTTGTCATAC AGCACAGATC CCATCACCTG CAGCAAAATC 
TCTCTGGAAG AAAGGATCAT GTCAAACCTC AAAAATCTTG TCACAAACTC TTTGGTAGTG 
GAGAGACAGC CATGCATGCC GACCCAACTG CAGAGACCTT TAGTGCTGAA GACAGGAGTT 
CTGTTCACCC TCAAATTACG GCTGCTCGTA AAAATTCCGG AATTTAACCA CACTGTTCGG 
GTGAAGGTGC AATTTGATAA GGATATCGTT GAAAAACGAA AAGGGTTTCG TATGTTCAAC 
ATCTTGGGAA CATCCATGAA GGTGATGAAC ATGGAGGAGT CCAATGGAAT GGCAGCAGAA 
TTTCGTCATC TGCAATTGAA AGAGAGGAAA GTTACTGGAA ACAGAACCAG TGAGGGTCCG 
CTGATTGTCA CAGAGGAGCT CCACTCCATC ACCTTTGAGG CTGAGCTTTG CTGGTCTGGG 
TTGGTCATTA ACTTTGAGAC AACATCTCTG CCCATAGTCG TGATCTCCAA CGTCAGTCAG 
CTGCCCAGTG GATGGGCGTC CATTATGTGG TACAACATGC TGATCTCTGA ACCAAAGAAC 
CTGTCCTTTT TCGTGACTCC TCCACCGGCC ACATGGGGTC AGCTACAGGA AGTGCTGAGC 
TGGCAGTTTT CCTCCATCAC CAAACGAGGC CTTAATCCTG AACAGTTAAG CATGCTGGGA 
AATAAACTGC TGGGTCCTAA AGCGGCATCG GATCCTGAAG CTCAGATTCC CTGGAACCGA 
TTCTGTAAGT CTGGCAGTGA AAAGAACTTT ACCTTTTGGC TGTGGATTGA AGCAGTTCTT 
GACCTGATAA AGAGACATTT GCTGAGCCTG TGGGATGATG GGTGCATCAT GGGATTTGTG 
ACCAAAGATC GAACTAAATC TCTGCTCAAC AACAAAGCTC CAGGGACGTT TCTGCTGCGC 
TTCAGTGAAA GCAACCGTGA CGGAGCCATT ACGTTCAGCT GGGTTGAACA CGATGCAAAT 
GAGGATCCAC AGATTCGCTC CGTGGAGCCG TACACAAAGA AGGAGCTCTC CGCTGTTTCA 
CTTCCTGACA TCATTCGAAA CTACCGCGTA ATGGCCGCCG ACAACGTTCC CGAAAACCCT 
CTGCGCTTCC TGTATCCTCA GATTCCCAAA GACGATGCCT TCAAGAAATA CTACACCAAG 
CCCACTGACA AGCAAGAACC AATGGATGTT GATAAGAAGG CAGACGAGGG ATACATTAGC 
ACCACTCTCA TCTCCATCTC TGAAATGAAA CCACAAGAAT ATAACGAGAA CCTCATGCCA 
ATGTCACCTG AGGTCTACGG CGAGCTGGAG CGCATGAATC GATTCGATAC TGTACAATTG 
GAGCCAGCAG ACTTGATGAC AATGACATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mutation of
Journal of medical genetics55(5)298-306(2018 05)
Gao X,Yuan YY,Lin QF,Xu JC,Wang WQ,Qiao YH,Kang DY,Bai D,Xin F,Huang SS,Qiu SW,Guan LP,Su Y,Wang GJ,Han MY,Jiang Y,Liu HK,Dai P

MicroRNA-223 Suppresses the Canonical NF-κB Pathway in Basal Keratinocytes to Dampen Neutrophilic Inflammation.
Cell reports22(7)1810-1823(2018 02)
Zhou W,Pal AS,Hsu AY,Gurol T,Zhu X,Wirbisky-Hershberger SE,Freeman JL,Kasinski AL,Deng Q

Irf8 regulates the progression of myeloproliferative neoplasm-like syndrome via Mertk signaling in zebrafish.
Leukemia32(1)149-158(2018 01)
Zhao F,Shi Y,Huang Y,Zhan Y,Zhou L,Li Y,Wan Y,Li H,Huang H,Ruan H,Luo L,Li L

Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling.
Development (Cambridge, England)144(16)2925-2939(2017 08)
Chernyavskaya Y,Mudbhary R,Zhang C,Tokarz D,Jacob V,Gopinath S,Sun X,Wang S,Magnani E,Madakashira BP,Yoder JA,Hoshida Y,Sadler KC

Frontiers in cellular and infection microbiology7334(2017)
Díaz-Pascual F,Ortíz-Severín J,Varas MA,Allende ML,Chávez FP

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stat1a cDNA ORF clone, Danio rerio(zebrafish)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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