xbp1 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	xbp1
Entrez Gene ID	140614
Full Name	X-box binding protein 1
Synonyms	cb918,id:ibd1195,treb5,trebf,wu:fb02h05,wu:fb63f10,xbp1a,xbp1b
General protein information	Preferred Names X-box binding protein 1 Names X-box-binding protein 1 X-box binding protein 1B
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_131874.1	NP_571949.1	X-box-binding protein 1

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	xbp1	NP_571949.1
Gallus gallus (chicken)	XBP1	NP_001006192.2
Xenopus tropicalis (tropical clawed frog)	xbp1	NP_001001199.1
Pan troglodytes (chimpanzee)	XBP1	XP_515053.2

Gene Ontology
Bibliography

Related articles in PubMed

Mechanism of isoniazid-induced hepatotoxicity in zebrafish larvae: Activation of ROS-mediated ERS, apoptosis and the Nrf2 pathway.
Jia ZL, Cen J, Wang JB, Zhang F, Xia Q, Wang X, Chen XQ, Wang RC, Hsiao CD, Liu KC, Zhang Y
Chemosphere227541-550(2019 Jul)

Hepatotoxicity Induced by Isoniazid-Lipopolysaccharide through Endoplasmic Reticulum Stress, Autophagy, and Apoptosis Pathways in Zebrafish.
Zhang Y, Cen J, Jia Z, Hsiao CD, Xia Q, Wang X, Chen X, Wang R, Jiang Z, Zhang L, Liu K
Antimicrobial agents and chemotherapy63(5)(2019 05)

In vitro and in vivo studies of oxidative stress responses against acrylamide toxicity in zebrafish.
Komoike Y, Matsuoka M
Journal of hazardous materials365430-439(2019 Mar)

3-ketodihydrosphingosine reductase mutation induces steatosis and hepatic injury in zebrafish.
Park KH, Ye ZW, Zhang J, Hammad SM, Townsend DM, Rockey DC, Kim SH
Scientific reports9(1)1138(2019 Feb)

Xiaoaiping Induces Developmental Toxicity in Zebrafish Embryos Through Activation of ER Stress, Apoptosis and the Wnt Pathway.
Li J, Zhang Y, Liu K, He Q, Sun C, Han J, Han L, Tian Q
Frontiers in pharmacology91250(2018)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following xbp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the xbp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa01451	NM_131874.1 Latest version!	Danio rerio X-box binding protein 1 (xbp1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

xbp1 ( NM_131874.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_571949.1 Danio rerio X-box binding protein 1 (xbp1), mRNA.

Price & Availability↑

CloneID	ODa01451
Clone ID Related Accession (Same CDS sequence)	NM_131874.1
Accession Version	NM_131874.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 792bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1576771200000
Organism	Danio rerio(zebrafish)
Product	X-box-binding protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY029577.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY029577.1, CK445306.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476737, SAMEA4476744 [ECO:0000348] ##Evidence-Data-END##

ATGGTCGTAG TTACAGCAGG GACCGGAGGA GCCCACAAAG TCCTCCTGAT ATCGGGAAAA 
CAGAGCGCTT CGACCGGCGC GACACAGGGC GGGTACAGCC GCTCAATATC TGTCATGATA 
CCGAATCAAG CCTCTTCAGA TTCAGACTCC ACCACCTCTG GACCACCACT GAGAAAACGA 
CAGAGACTCA CACATCTGAG CCCAGAGGAA AAAGCACTTC GAAGGAAATT AAAGAACAGA 
GTTGCTGCAC AGACAGCAAG AGACAGAAAA AAGGCAAAAA TGGGGGAGTT GGAACAGCAA 
GTGCTGGAGT TGGAGCTGGA GAATCAGAAA CTTCACGTTG AGAACAGGCT GTTGCGAGAC 
AAGACGAGTG ATCTGCTCAG TGAGAATGAG GAGCTGAGAC AGAGACTGGG GTTGGATACC 
TTGGAAACAA AGGAGCAGGT TCAGGTACTG GAGTCCGCAG TGAGCGATTT AGGTTTGGTG 
ACCGGGTCTT CTGAGTCCGC AGCACTCAGG CTACGTGTGC CTCCGCAGCA GGTGCAGGCC 
CAGCAGTCCC CAAATCTGAA GACTTCACCA TGGATACTCA CAGCCCTGGC CCTGCAGACT 
CTGAGTCTGA TCTCCTGCTT GGTATTCTGG ACATCCTTGA CCCCGAGCTC TTCCTCAAGA 
CAGACCTTCC TGAAGCACAG GAGCCTCAGC AGGAGCTCGT GCTGGTGGGG GGTGCAGGAG 
AGCAAGTACC TTCCTCCGCA CCTGCAGCTT TGGGGCCCGC ACCAGTTAAG CTGGAAGCCC 
TTAATGAACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_571949.1
CDS	113..904
Translation	MVVVTAGTGGAHKVLLISGKQSASTGATQGGYSRSISVMIPNQASSDSDSTTSGPPLRKRQRLTHLSPEEKALRRKLKNRVAAQTARDRKKAKMGELEQQVLELELENQKLHVENRLLRDKTSDLLSENEELRQRLGLDTLETKEQVQVLESAVSDLGLVTGSSESAALRLRVPPQQVQAQQSPNLKTSPWILTALALQTLSLISCLVFWTSLTPSSSSRQTFLKHRSLSRSSCWWGVQESKYLPPHLQLWGPHQLSWKPLMN

Target ORF information:

RefSeq Version	NM_131874.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio X-box binding protein 1 (xbp1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_131874.1

ORF Insert Sequence:

ATGGTCGTAG TTACAGCAGG GACCGGAGGA GCCCACAAAG TCCTCCTGAT ATCGGGAAAA 
CAGAGCGCTT CGACCGGCGC GACACAGGGC GGGTACAGCC GCTCAATATC TGTCATGATA 
CCGAATCAAG CCTCTTCAGA TTCAGACTCC ACCACCTCTG GACCACCACT GAGAAAACGA 
CAGAGACTCA CACATCTGAG CCCAGAGGAA AAAGCACTTC GAAGGAAATT AAAGAACAGA 
GTTGCTGCAC AGACAGCAAG AGACAGAAAA AAGGCAAAAA TGGGGGAGTT GGAACAGCAA 
GTGCTGGAGT TGGAGCTGGA GAATCAGAAA CTTCACGTTG AGAACAGGCT GTTGCGAGAC 
AAGACGAGTG ATCTGCTCAG TGAGAATGAG GAGCTGAGAC AGAGACTGGG GTTGGATACC 
TTGGAAACAA AGGAGCAGGT TCAGGTACTG GAGTCCGCAG TGAGCGATTT AGGTTTGGTG 
ACCGGGTCTT CTGAGTCCGC AGCACTCAGG CTACGTGTGC CTCCGCAGCA GGTGCAGGCC 
CAGCAGTCCC CAAATCTGAA GACTTCACCA TGGATACTCA CAGCCCTGGC CCTGCAGACT 
CTGAGTCTGA TCTCCTGCTT GGTATTCTGG ACATCCTTGA CCCCGAGCTC TTCCTCAAGA 
CAGACCTTCC TGAAGCACAG GAGCCTCAGC AGGAGCTCGT GCTGGTGGGG GGTGCAGGAG 
AGCAAGTACC TTCCTCCGCA CCTGCAGCTT TGGGGCCCGC ACCAGTTAAG CTGGAAGCCC 
TTAATGAACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mechanism of isoniazid-induced hepatotoxicity in zebrafish larvae: Activation of ROS-mediated ERS, apoptosis and the Nrf2 pathway.
Chemosphere227541-550(2019 Jul)
Jia ZL,Cen J,Wang JB,Zhang F,Xia Q,Wang X,Chen XQ,Wang RC,Hsiao CD,Liu KC,Zhang Y

Hepatotoxicity Induced by Isoniazid-Lipopolysaccharide through Endoplasmic Reticulum Stress, Autophagy, and Apoptosis Pathways in Zebrafish.
Antimicrobial agents and chemotherapy63(5)(2019 05)
Zhang Y,Cen J,Jia Z,Hsiao CD,Xia Q,Wang X,Chen X,Wang R,Jiang Z,Zhang L,Liu K

In vitro and in vivo studies of oxidative stress responses against acrylamide toxicity in zebrafish.
Journal of hazardous materials365430-439(2019 Mar)
Komoike Y,Matsuoka M

3-ketodihydrosphingosine reductase mutation induces steatosis and hepatic injury in zebrafish.
Scientific reports9(1)1138(2019 Feb)
Park KH,Ye ZW,Zhang J,Hammad SM,Townsend DM,Rockey DC,Kim SH

Xiaoaiping Induces Developmental Toxicity in Zebrafish Embryos Through Activation of ER Stress, Apoptosis and the Wnt Pathway.
Frontiers in pharmacology91250(2018)
Li J,Zhang Y,Liu K,He Q,Sun C,Han J,Han L,Tian Q