casp8l1 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	casp8l1
Entrez Gene ID	100049706
Full Name	caspase 8, apoptosis-related cysteine peptidase, like 1
General protein information	Preferred Names caspase 8, apoptosis-related cysteine peptidase, like 1 Names caspase 8, apoptosis-related cysteine peptidase, like 1
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005165822.3	XP_005165879.2	caspase 8, apoptosis-related cysteine peptidase, like 1 isoform X1
XM_005165822.4	XP_005165879.2	caspase 8, apoptosis-related cysteine peptidase, like 1 isoform X1
XM_017356418.1	XP_017211907.1	caspase 8, apoptosis-related cysteine peptidase, like 1 isoform X2
NM_001098619.1	NP_001092089.1	caspase 8, apoptosis-related cysteine peptidase, like 1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Casp8	NP_071613.1
Xenopus tropicalis (tropical clawed frog)	casp8	XP_002936586.2
Homo sapiens (human)	CASP8	NP_001073594.1
Bos taurus (cattle)	CASP8	NP_001039435.1
Danio rerio (zebrafish)	casp8	NP_571585.2
Danio rerio (zebrafish)	casp8l1	NP_001092089.1
Pan troglodytes (chimpanzee)	CASP8	XP_001172193.1
Canis lupus familiaris (dog)	CASP8	NP_001041494.1
Gallus gallus (chicken)	CASP8	NP_989923.1
Macaca mulatta (Rhesus monkey)	CASP8	XP_001091080.2
Mus musculus (house mouse)	Casp8	NP_001264855.1

Gene Ontology
Bibliography

Related articles in PubMed

Characterization of the caspase family in zebrafish.
Spead O, Verreet T, Donelson CJ, Poulain FE
PloS one13(5)e0197966(2018)

Early developmental exposure to pentachlorophenol causes alterations on mRNA expressions of caspase protease family in zebrafish embryos.
Zhao J, Huang G, Xu T, Yin D, Bai J, Gu W
Chemosphere180141-148(2017 Aug)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

Conservation of structure and function in vertebrate c-FLIP proteins despite rapid evolutionary change.
Sakamaki K, Iwabe N, Iwata H, Imai K, Takagi C, Chiba K, Shukunami C, Tomii K, Ueno N
Biochemistry and biophysics reports3175-189(2015 Sep)

Delineation of the cell-extrinsic apoptosis pathway in the zebrafish.
Eimon PM, Kratz E, Varfolomeev E, Hymowitz SG, Stern H, Zha J, Ashkenazi A
Cell death and differentiation13(10)1619-30(2006 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following casp8l1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the casp8l1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ODa31210	NM_001098619.1 Latest version!	Danio rerio caspase 8, apoptosis-related cysteine peptidase, like 1 (casp8l1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
ODa48440	XM_005165822.4 Latest version!	Danio rerio caspase 8, apoptosis-related cysteine peptidase, like 1 (casp8l1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
ODa48441	XM_017356418.1 Latest version!	Danio rerio caspase 8, apoptosis-related cysteine peptidase, like 1 (casp8l1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
ODa48440	XM_005165822.3	Danio rerio caspase 8, apoptosis-related cysteine peptidase, like 1 (casp8l1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

casp8l1 ( NM_001098619.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001092089.1 Danio rerio caspase 8, apoptosis-related cysteine peptidase, like 1 (casp8l1), mRNA.

Price & Availability↑

CloneID	ODa31210
Clone ID Related Accession (Same CDS sequence)	NM_001098619.1
Accession Version	NM_001098619.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 993bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1556380800000
Organism	Danio rerio(zebrafish)
Product	caspase 8, apoptosis-related cysteine peptidase, like 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from DQ812121.1. ##Evidence-Data-START## Transcript exon combination :: DQ812121.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGGATAAAA CTAGTAATCC TAACAACAGT AATCAAATAA ATCGAGCTTC CCCAAATGAG 
CAAGAGAAAA TCAAAACAGA TGAACCGAAG AGGAAAAATA CATCACAGGA AGATAAGGAA 
AACCTACATA AAGGTGTCCA AAATAATAAT TCACCTAAAA GACAGCGGGA GCCTCTTCAA 
TCCACCTGCA ATATTTCTGA CCATTATCCT AAAAGGAAGC GTGCAGTGAC AGAGCAGAAA 
GAGTGCTATT CCATGTCAAA TCGACCTCTT GGATATTGTT TGATCATCAA CAATTATAAA 
TTTGAAAGTG CATCACTTGC AGACCGGAGA GGGACTGATA GAGATAAAGA CGATCTCACC 
AAAGTCTTTG AGAAAATGTA TTTCAAAGTT GAAGTGCGGG ACGATTTGCA AGCCTCAGTC 
ATGCGAAATG TGATAAAAGA ATTTGCAGAG AAGGATCACT CTCAGATGAA TGCTTTTGTC 
TGCTGCATCC TCACCCATGG AGAGAAAGGC ACTGTTCTGG GAACAGACGG AAAACAAGTT 
CCCATTCGTG AACTCTCACA GCCGTTTGCT GAATGCCGTT CTCTAGCCAG TAAACCCAAA 
CTTTTCTTCA TTCAGGCCTG TCAGGGCAAT ATGAGACAGC AAGGTTTGTG GATGGCACAT 
GAGCGGGAGA ACACCACAGA AGAGGAAGCA TATGAGGAGG ATGCTCATGC TGCAGGGAAT 
TACAGTATCC CTATGGATGC AGATTTCCTC TTTGCTATTG CAACGGTGGA GCATTGTAAA 
TCCTTCCGCC ACATTAAAAA TGGGTCCATC TTTATTCAGG AGCTCTGCAA GCAGCTGGAA 
AGGGGCTGTG CACAGAAAAA GGACATACTC TCAATTTTAA CCGCGGTAAA TGGAGTAGTG 
GGCTCCAAAA TTCTACAGGG TTACAAGCAG ATGCCTGAGG TTCGCTACAC TCTGACCAAA 
GCACTGGTCC TGCCCATGAA TGGAGTCTCC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001092089.1
CDS	1..993
Translation	MDKTSNPNNSNQINRASPNEQEKIKTDEPKRKNTSQEDKENLHKGVQNNNSPKRQREPLQSTCNISDHYPKRKRAVTEQKECYSMSNRPLGYCLIINNYKFESASLADRRGTDRDKDDLTKVFEKMYFKVEVRDDLQASVMRNVIKEFAEKDHSQMNAFVCCILTHGEKGTVLGTDGKQVPIRELSQPFAECRSLASKPKLFFIQACQGNMRQQGLWMAHERENTTEEEAYEEDAHAAGNYSIPMDADFLFAIATVEHCKSFRHIKNGSIFIQELCKQLERGCAQKKDILSILTAVNGVVGSKILQGYKQMPEVRYTLTKALVLPMNGVS

Target ORF information:

RefSeq Version	NM_001098619.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio caspase 8, apoptosis-related cysteine peptidase, like 1 (casp8l1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001098619.1

ORF Insert Sequence:

ATGGATAAAA CTAGTAATCC TAACAACAGT AATCAAATAA ATCGAGCTTC CCCAAATGAG 
CAAGAGAAAA TCAAAACAGA TGAACCGAAG AGGAAAAATA CATCACAGGA AGATAAGGAA 
AACCTACATA AAGGTGTCCA AAATAATAAT TCACCTAAAA GACAGCGGGA GCCTCTTCAA 
TCCACCTGCA ATATTTCTGA CCATTATCCT AAAAGGAAGC GTGCAGTGAC AGAGCAGAAA 
GAGTGCTATT CCATGTCAAA TCGACCTCTT GGATATTGTT TGATCATCAA CAATTATAAA 
TTTGAAAGTG CATCACTTGC AGACCGGAGA GGGACTGATA GAGATAAAGA CGATCTCACC 
AAAGTCTTTG AGAAAATGTA TTTCAAAGTT GAAGTGCGGG ACGATTTGCA AGCCTCAGTC 
ATGCGAAATG TGATAAAAGA ATTTGCAGAG AAGGATCACT CTCAGATGAA TGCTTTTGTC 
TGCTGCATCC TCACCCATGG AGAGAAAGGC ACTGTTCTGG GAACAGACGG AAAACAAGTT 
CCCATTCGTG AACTCTCACA GCCGTTTGCT GAATGCCGTT CTCTAGCCAG TAAACCCAAA 
CTTTTCTTCA TTCAGGCCTG TCAGGGCAAT ATGAGACAGC AAGGTTTGTG GATGGCACAT 
GAGCGGGAGA ACACCACAGA AGAGGAAGCA TATGAGGAGG ATGCTCATGC TGCAGGGAAT 
TACAGTATCC CTATGGATGC AGATTTCCTC TTTGCTATTG CAACGGTGGA GCATTGTAAA 
TCCTTCCGCC ACATTAAAAA TGGGTCCATC TTTATTCAGG AGCTCTGCAA GCAGCTGGAA 
AGGGGCTGTG CACAGAAAAA GGACATACTC TCAATTTTAA CCGCGGTAAA TGGAGTAGTG 
GGCTCCAAAA TTCTACAGGG TTACAAGCAG ATGCCTGAGG TTCGCTACAC TCTGACCAAA 
GCACTGGTCC TGCCCATGAA TGGAGTCTCC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

casp8l1 ( XM_005165822.3 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_005165879.2 Danio rerio caspase 8, apoptosis-related cysteine peptidase, like 1 (casp8l1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa48440
Clone ID Related Accession (Same CDS sequence)	XM_005165822.3 , XM_005165822.4
Accession Version	XM_005165822.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 993bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466611200000
Organism	Danio rerio(Zebrafish)
Product	caspase 8, apoptosis-related cysteine peptidase, like 1 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007117.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XM_005165822.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATAAAA CTAGTAATCC TAACAACAGT AATCAAATAA ATCGAGCTTC CCCAAATGAG 
CAAGAGAAAA TCAAAACAGA TGAACCGAAG AGGAAAAATA CATCACAGGA AGATAAGGAA 
AACCTACATA AAGGTGTCCA AAATAATAAT TCACCTAAAA GACAGCGGGA GCCTCTTCAA 
TCCACCTGCA ATATTTCTGA CCATTATCCT AAAAGGAAGC GTGCAGTGAC AGAGCAGAAA 
GAGTGCTATT CCATGTCAAA TCGACCTCTT GGATATTGTT TGATCATCAA CAATTATAAA 
TTTGAAAGTG CATCACTTGC AGACCGGAGA GGGACTGATA GAGATAAAGA CGATCTCACC 
AAAGTCTTTG AGAAAATGTA TTTCAAAGTT GAAGTGCGGG ACGATTTACA AGCCTCAGAC 
ATGCGAAATG TGATAAAAGA ATTTGCAGAG AAGGATCACT CTCAGATGAA TGCTTTTGTC 
TGCTGCATCC TCACCCATGG AGAGAAAGGC ACTGTTCTGG GAACAGACGG AAAACAAGTT 
CCGATTCGTG AACTCTCACA GCCGTTTGCT GAATGCCGTT CTCTAGCCAG TAAACCCAAA 
CTGTTCTTCA TTCAGGCCTG TCAGGGCAAT ATGAGACAGC AAGGTTTGTG GATGGCACAT 
GAGCGGGAGA ACACCACAGA AGAGGAAGCA TATGAGGAGG ATGCTCATGC TGCAGGGAAT 
TACAGTATCC CTATGGATGC AGATTTCCTC TTTGCTATTG CAACGGTGGA GCATTTTAGA 
TCCTACCGCC ACATTACAAA TGGGTCCATC TTTATTCAGG TGCTCTGCAA GCAGCTGGAA 
AGGGGCTGTG CACAGAAAAA GGACATACTC TCAATTTTAA CCGCGGTAAA TGGAGTAGTG 
GGCTCCAAAA TTCTACAGGG TTACAAGCAG ATGCCTGAGG TTCGCTACAC TCTGACCAAA 
GCACTGGTCC TGCCCATGAA TGGAGTCTCC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005165879.2
CDS	404..1396
Translation	MDKTSNPNNSNQINRASPNEQEKIKTDEPKRKNTSQEDKENLHKGVQNNNSPKRQREPLQSTCNISDHYPKRKRAVTEQKECYSMSNRPLGYCLIINNYKFESASLADRRGTDRDKDDLTKVFEKMYFKVEVRDDLQASDMRNVIKEFAEKDHSQMNAFVCCILTHGEKGTVLGTDGKQVPIRELSQPFAECRSLASKPKLFFIQACQGNMRQQGLWMAHERENTTEEEAYEEDAHAAGNYSIPMDADFLFAIATVEHFRSYRHITNGSIFIQVLCKQLERGCAQKKDILSILTAVNGVVGSKILQGYKQMPEVRYTLTKALVLPMNGVS

Target ORF information:

RefSeq Version	XM_005165822.3
Organism	Danio rerio(Zebrafish)
Definition	Danio rerio caspase 8, apoptosis-related cysteine peptidase, like 1 (casp8l1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005165822.3

ORF Insert Sequence:

ATGGATAAAA CTAGTAATCC TAACAACAGT AATCAAATAA ATCGAGCTTC CCCAAATGAG 
CAAGAGAAAA TCAAAACAGA TGAACCGAAG AGGAAAAATA CATCACAGGA AGATAAGGAA 
AACCTACATA AAGGTGTCCA AAATAATAAT TCACCTAAAA GACAGCGGGA GCCTCTTCAA 
TCCACCTGCA ATATTTCTGA CCATTATCCT AAAAGGAAGC GTGCAGTGAC AGAGCAGAAA 
GAGTGCTATT CCATGTCAAA TCGACCTCTT GGATATTGTT TGATCATCAA CAATTATAAA 
TTTGAAAGTG CATCACTTGC AGACCGGAGA GGGACTGATA GAGATAAAGA CGATCTCACC 
AAAGTCTTTG AGAAAATGTA TTTCAAAGTT GAAGTGCGGG ACGATTTACA AGCCTCAGAC 
ATGCGAAATG TGATAAAAGA ATTTGCAGAG AAGGATCACT CTCAGATGAA TGCTTTTGTC 
TGCTGCATCC TCACCCATGG AGAGAAAGGC ACTGTTCTGG GAACAGACGG AAAACAAGTT 
CCGATTCGTG AACTCTCACA GCCGTTTGCT GAATGCCGTT CTCTAGCCAG TAAACCCAAA 
CTGTTCTTCA TTCAGGCCTG TCAGGGCAAT ATGAGACAGC AAGGTTTGTG GATGGCACAT 
GAGCGGGAGA ACACCACAGA AGAGGAAGCA TATGAGGAGG ATGCTCATGC TGCAGGGAAT 
TACAGTATCC CTATGGATGC AGATTTCCTC TTTGCTATTG CAACGGTGGA GCATTTTAGA 
TCCTACCGCC ACATTACAAA TGGGTCCATC TTTATTCAGG TGCTCTGCAA GCAGCTGGAA 
AGGGGCTGTG CACAGAAAAA GGACATACTC TCAATTTTAA CCGCGGTAAA TGGAGTAGTG 
GGCTCCAAAA TTCTACAGGG TTACAAGCAG ATGCCTGAGG TTCGCTACAC TCTGACCAAA 
GCACTGGTCC TGCCCATGAA TGGAGTCTCC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

casp8l1 ( XM_005165822.4 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_005165879.2 Danio rerio caspase 8, apoptosis-related cysteine peptidase, like 1 (casp8l1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa48440
Clone ID Related Accession (Same CDS sequence)	XM_005165822.3 , XM_005165822.4
Accession Version	XM_005165822.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 993bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1497369600000
Organism	Danio rerio(zebrafish)
Product	caspase 8, apoptosis-related cysteine peptidase, like 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007117.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XM_005165822.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATAAAA CTAGTAATCC TAACAACAGT AATCAAATAA ATCGAGCTTC CCCAAATGAG 
CAAGAGAAAA TCAAAACAGA TGAACCGAAG AGGAAAAATA CATCACAGGA AGATAAGGAA 
AACCTACATA AAGGTGTCCA AAATAATAAT TCACCTAAAA GACAGCGGGA GCCTCTTCAA 
TCCACCTGCA ATATTTCTGA CCATTATCCT AAAAGGAAGC GTGCAGTGAC AGAGCAGAAA 
GAGTGCTATT CCATGTCAAA TCGACCTCTT GGATATTGTT TGATCATCAA CAATTATAAA 
TTTGAAAGTG CATCACTTGC AGACCGGAGA GGGACTGATA GAGATAAAGA CGATCTCACC 
AAAGTCTTTG AGAAAATGTA TTTCAAAGTT GAAGTGCGGG ACGATTTACA AGCCTCAGAC 
ATGCGAAATG TGATAAAAGA ATTTGCAGAG AAGGATCACT CTCAGATGAA TGCTTTTGTC 
TGCTGCATCC TCACCCATGG AGAGAAAGGC ACTGTTCTGG GAACAGACGG AAAACAAGTT 
CCGATTCGTG AACTCTCACA GCCGTTTGCT GAATGCCGTT CTCTAGCCAG TAAACCCAAA 
CTGTTCTTCA TTCAGGCCTG TCAGGGCAAT ATGAGACAGC AAGGTTTGTG GATGGCACAT 
GAGCGGGAGA ACACCACAGA AGAGGAAGCA TATGAGGAGG ATGCTCATGC TGCAGGGAAT 
TACAGTATCC CTATGGATGC AGATTTCCTC TTTGCTATTG CAACGGTGGA GCATTTTAGA 
TCCTACCGCC ACATTACAAA TGGGTCCATC TTTATTCAGG TGCTCTGCAA GCAGCTGGAA 
AGGGGCTGTG CACAGAAAAA GGACATACTC TCAATTTTAA CCGCGGTAAA TGGAGTAGTG 
GGCTCCAAAA TTCTACAGGG TTACAAGCAG ATGCCTGAGG TTCGCTACAC TCTGACCAAA 
GCACTGGTCC TGCCCATGAA TGGAGTCTCC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005165879.2
CDS	857..1849
Translation	MDKTSNPNNSNQINRASPNEQEKIKTDEPKRKNTSQEDKENLHKGVQNNNSPKRQREPLQSTCNISDHYPKRKRAVTEQKECYSMSNRPLGYCLIINNYKFESASLADRRGTDRDKDDLTKVFEKMYFKVEVRDDLQASDMRNVIKEFAEKDHSQMNAFVCCILTHGEKGTVLGTDGKQVPIRELSQPFAECRSLASKPKLFFIQACQGNMRQQGLWMAHERENTTEEEAYEEDAHAAGNYSIPMDADFLFAIATVEHFRSYRHITNGSIFIQVLCKQLERGCAQKKDILSILTAVNGVVGSKILQGYKQMPEVRYTLTKALVLPMNGVS

Target ORF information:

RefSeq Version	XM_005165822.4
Organism	Danio rerio(zebrafish)
Definition	Danio rerio caspase 8, apoptosis-related cysteine peptidase, like 1 (casp8l1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005165822.4

ORF Insert Sequence:

ATGGATAAAA CTAGTAATCC TAACAACAGT AATCAAATAA ATCGAGCTTC CCCAAATGAG 
CAAGAGAAAA TCAAAACAGA TGAACCGAAG AGGAAAAATA CATCACAGGA AGATAAGGAA 
AACCTACATA AAGGTGTCCA AAATAATAAT TCACCTAAAA GACAGCGGGA GCCTCTTCAA 
TCCACCTGCA ATATTTCTGA CCATTATCCT AAAAGGAAGC GTGCAGTGAC AGAGCAGAAA 
GAGTGCTATT CCATGTCAAA TCGACCTCTT GGATATTGTT TGATCATCAA CAATTATAAA 
TTTGAAAGTG CATCACTTGC AGACCGGAGA GGGACTGATA GAGATAAAGA CGATCTCACC 
AAAGTCTTTG AGAAAATGTA TTTCAAAGTT GAAGTGCGGG ACGATTTACA AGCCTCAGAC 
ATGCGAAATG TGATAAAAGA ATTTGCAGAG AAGGATCACT CTCAGATGAA TGCTTTTGTC 
TGCTGCATCC TCACCCATGG AGAGAAAGGC ACTGTTCTGG GAACAGACGG AAAACAAGTT 
CCGATTCGTG AACTCTCACA GCCGTTTGCT GAATGCCGTT CTCTAGCCAG TAAACCCAAA 
CTGTTCTTCA TTCAGGCCTG TCAGGGCAAT ATGAGACAGC AAGGTTTGTG GATGGCACAT 
GAGCGGGAGA ACACCACAGA AGAGGAAGCA TATGAGGAGG ATGCTCATGC TGCAGGGAAT 
TACAGTATCC CTATGGATGC AGATTTCCTC TTTGCTATTG CAACGGTGGA GCATTTTAGA 
TCCTACCGCC ACATTACAAA TGGGTCCATC TTTATTCAGG TGCTCTGCAA GCAGCTGGAA 
AGGGGCTGTG CACAGAAAAA GGACATACTC TCAATTTTAA CCGCGGTAAA TGGAGTAGTG 
GGCTCCAAAA TTCTACAGGG TTACAAGCAG ATGCCTGAGG TTCGCTACAC TCTGACCAAA 
GCACTGGTCC TGCCCATGAA TGGAGTCTCC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

casp8l1 ( XM_017356418.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_017211907.1 Danio rerio caspase 8, apoptosis-related cysteine peptidase, like 1 (casp8l1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ODa48441
Clone ID Related Accession (Same CDS sequence)	XM_017356418.1
Accession Version	XM_017356418.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 870bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466611200000
Organism	Danio rerio(Zebrafish)
Product	caspase 8, apoptosis-related cysteine peptidase, like 1 isoform X2
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007117.6) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATAAAA CTAGTAATCC TAACAACAGT AATCAAATAA ATCGAGCTTC CCCAAATGAG 
CAAGAGAAAA TCAAAACAGA TGAACCGAAG AGGAAAAATA CATCACAGGA AGATAAGGAA 
AACCTACATA AAGGTGTCCA AAATAATAAT TCACCTAAAA GACAGCGGGA GCCTCTTCAA 
TCCACCTGCA ATATTTCTGA CCATTATCCT AAAAGGAAGC GTGCAGACGA TCTCACCAAA 
GTCTTTGAGA AAATGTATTT CAAAGTTGAA GTGCGGGACG ATTTACAAGC CTCAGACATG 
CGAAATGTGA TAAAAGAATT TGCAGAGAAG GATCACTCTC AGATGAATGC TTTTGTCTGC 
TGCATCCTCA CCCATGGAGA GAAAGGCACT GTTCTGGGAA CAGACGGAAA ACAAGTTCCG 
ATTCGTGAAC TCTCACAGCC GTTTGCTGAA TGCCGTTCTC TAGCCAGTAA ACCCAAACTG 
TTCTTCATTC AGGCCTGTCA GGGCAATATG AGACAGCAAG GTTTGTGGAT GGCACATGAG 
CGGGAGAACA CCACAGAAGA GGAAGCATAT GAGGAGGATG CTCATGCTGC AGGGAATTAC 
AGTATCCCTA TGGATGCAGA TTTCCTCTTT GCTATTGCAA CGGTGGAGCA TTTTAGATCC 
TACCGCCACA TTACAAATGG GTCCATCTTT ATTCAGGTGC TCTGCAAGCA GCTGGAAAGG 
GGCTGTGCAC AGAAAAAGGA CATACTCTCA ATTTTAACCG CGGTAAATGG AGTAGTGGGC 
TCCAAAATTC TACAGGGTTA CAAGCAGATG CCTGAGGTTC GCTACACTCT GACCAAAGCA 
CTGGTCCTGC CCATGAATGG AGTCTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017211907.1
CDS	571..1440
Translation	MDKTSNPNNSNQINRASPNEQEKIKTDEPKRKNTSQEDKENLHKGVQNNNSPKRQREPLQSTCNISDHYPKRKRADDLTKVFEKMYFKVEVRDDLQASDMRNVIKEFAEKDHSQMNAFVCCILTHGEKGTVLGTDGKQVPIRELSQPFAECRSLASKPKLFFIQACQGNMRQQGLWMAHERENTTEEEAYEEDAHAAGNYSIPMDADFLFAIATVEHFRSYRHITNGSIFIQVLCKQLERGCAQKKDILSILTAVNGVVGSKILQGYKQMPEVRYTLTKALVLPMNGVS

Target ORF information:

RefSeq Version	XM_017356418.1
Organism	Danio rerio(Zebrafish)
Definition	Danio rerio caspase 8, apoptosis-related cysteine peptidase, like 1 (casp8l1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017356418.1

ORF Insert Sequence:

ATGGATAAAA CTAGTAATCC TAACAACAGT AATCAAATAA ATCGAGCTTC CCCAAATGAG 
CAAGAGAAAA TCAAAACAGA TGAACCGAAG AGGAAAAATA CATCACAGGA AGATAAGGAA 
AACCTACATA AAGGTGTCCA AAATAATAAT TCACCTAAAA GACAGCGGGA GCCTCTTCAA 
TCCACCTGCA ATATTTCTGA CCATTATCCT AAAAGGAAGC GTGCAGACGA TCTCACCAAA 
GTCTTTGAGA AAATGTATTT CAAAGTTGAA GTGCGGGACG ATTTACAAGC CTCAGACATG 
CGAAATGTGA TAAAAGAATT TGCAGAGAAG GATCACTCTC AGATGAATGC TTTTGTCTGC 
TGCATCCTCA CCCATGGAGA GAAAGGCACT GTTCTGGGAA CAGACGGAAA ACAAGTTCCG 
ATTCGTGAAC TCTCACAGCC GTTTGCTGAA TGCCGTTCTC TAGCCAGTAA ACCCAAACTG 
TTCTTCATTC AGGCCTGTCA GGGCAATATG AGACAGCAAG GTTTGTGGAT GGCACATGAG 
CGGGAGAACA CCACAGAAGA GGAAGCATAT GAGGAGGATG CTCATGCTGC AGGGAATTAC 
AGTATCCCTA TGGATGCAGA TTTCCTCTTT GCTATTGCAA CGGTGGAGCA TTTTAGATCC 
TACCGCCACA TTACAAATGG GTCCATCTTT ATTCAGGTGC TCTGCAAGCA GCTGGAAAGG 
GGCTGTGCAC AGAAAAAGGA CATACTCTCA ATTTTAACCG CGGTAAATGG AGTAGTGGGC 
TCCAAAATTC TACAGGGTTA CAAGCAGATG CCTGAGGTTC GCTACACTCT GACCAAAGCA 
CTGGTCCTGC CCATGAATGG AGTCTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Characterization of the caspase family in zebrafish.
PloS one13(5)e0197966(2018)
Spead O,Verreet T,Donelson CJ,Poulain FE

Early developmental exposure to pentachlorophenol causes alterations on mRNA expressions of caspase protease family in zebrafish embryos.
Chemosphere180141-148(2017 Aug)
Zhao J,Huang G,Xu T,Yin D,Bai J,Gu W

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

Conservation of structure and function in vertebrate c-FLIP proteins despite rapid evolutionary change.
Biochemistry and biophysics reports3175-189(2015 Sep)
Sakamaki K,Iwabe N,Iwata H,Imai K,Takagi C,Chiba K,Shukunami C,Tomii K,Ueno N

Delineation of the cell-extrinsic apoptosis pathway in the zebrafish.
Cell death and differentiation13(10)1619-30(2006 Oct)
Eimon PM,Kratz E,Varfolomeev E,Hymowitz SG,Stern H,Zha J,Ashkenazi A

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casp8l1 cDNA ORF clone, Danio rerio(zebrafish)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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