| Gene Symbol | nkd2a |
| Entrez Gene ID | 100049175 |
| Full Name | naked cuticle homolog 2a |
| Synonyms | nkd2 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Danio rerio(zebrafish) |
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nkd2a cDNA ORF clone, Danio rerio(zebrafish)
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Gene
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Clones
gRNAs
The following nkd2a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the nkd2a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID ODa01830 Clone ID Related Accession (Same CDS sequence) NM_001098197.1 Accession Version NM_001098197.1 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 1230bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1555862400000 Organism Danio rerio(zebrafish) Product protein naked cuticle homolog 2 Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from EF192161.1. ##Evidence-Data-START## Transcript exon combination :: EF192161.1 [ECO:0000332] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201ATGGGGAAAC TTCACTCCAA ACATGCTTGT AAACGTCGGG AAAATCCTGA GGGAGATAGT
TTTGTTGTGA ATGGCTTCAT TGCAAAAAGA GCAGCTGAAG AAGGCGAGCG ATACGGCAAC
AATCTGAAAG ATTATAAGAA CGAAGAGCTG AAGGACAGCC AGCCGACGCT GCTCCACTGC
CCTCTACAGG TGGTTTTGCC TCCAGAGAAA GCTGAAGGAT GTGAGAGTTT TCTTCAGTAT
TTGTCGCCTG ATGATGAAGA ACGAGACGCA CAAAAAGTGA CGAAGCGCAT CAGCCTGCAG
GATCTGGAGT GTAACGTGTC TCTGGCTGAA GACAACAGAC AGGAGTGGGT TTTCACACTC
TACGACTTTG ACAACAGTGG AAAAGTCACA AAAGAGGACA TGTCCAGTCT GATGCACACT
ATCTATGATG TGGTGGACGC CTCGGTCAAA CACTCCTGTA ACAGCAAACG CAGGAGCCTG
AGGGTCAAAC TGAGCGTCAC ACCAGAACCT GCAGCTCGCC GGAGAGACGC CACACACACT
GAAAGAGAAA CGAGTCATTT GAGTCAAGTT GAACCTGTTC GTTCAGAGGA GCATCGCAGC
GCAGACAGAC GACAGAGCAC ACACATCAGA GGCCAGACTG AGGCTCATGA GGGAAATCAT
TACTGCGTGG ATGAAAACAC AGAGAGACGA AATCATTACC TGGATCTGGC AGGAATAGAG
AACTACACGT CTAGATTTGA CAGTTCATCT CCGGATGCTG ATCAGGATCC CCCGTCTCGC
TCTTCACACA GTCAAAGTCG CCCCCATTCA CAGGAGCCCG AAACACATGT TTATCAGCGC
CGCTCACAGC TTATGGAGCC CTGTGTGGCC CCGGACCCCC GCCTGCGCAC CGGCCCCCAG
CTCATCAGAT CAAGATCCCC TAAAGGGTCG TCCAGATATC CTGGTGTCAT CCCGAATGTG
ACCAAAACCA GCAAGTGCCA CGGACACCAT CAGCCCATAT CGGCTGGTCA GGACGTTTAT
CATCTAACCC AGCAGAGCCA CACACACGCA CACACCCCGA GCGGCCTCCA GCACAGCCAC
AGCAGGAGGA TCAGATCCAG AGCCCGAGAA CAGCAGGCCC TGACACCGGT CAAAAACACC
AACGCTACTG CACTGGTCCA GAGACACGAA CACCATCACC ATCACGAACA CCACCATCAT
CACCACTACC ACCACTACCA CCAGACATGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_001091667.1 CDS 111..1340 Translation 
Target ORF information:
RefSeq Version NM_001098197.1 Organism Danio rerio(zebrafish) Definition Danio rerio NKD inhibitor of WNT signaling pathway 2a (nkd2a), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_001098197.1
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201ATGGGGAAAC TTCACTCCAA ACATGCTTGT AAACGTCGGG AAAATCCTGA GGGAGATAGT
TTTGTTGTGA ATGGCTTCAT TGCAAAAAGA GCAGCTGAAG AAGGCGAGCG ATACGGCAAC
AATCTGAAAG ATTATAAGAA CGAAGAGCTG AAGGACAGCC AGCCGACGCT GCTCCACTGC
CCTCTACAGG TGGTTTTGCC TCCAGAGAAA GCTGAAGGAT GTGAGAGTTT TCTTCAGTAT
TTGTCGCCTG ATGATGAAGA ACGAGACGCA CAAAAAGTGA CGAAGCGCAT CAGCCTGCAG
GATCTGGAGT GTAACGTGTC TCTGGCTGAA GACAACAGAC AGGAGTGGGT TTTCACACTC
TACGACTTTG ACAACAGTGG AAAAGTCACA AAAGAGGACA TGTCCAGTCT GATGCACACT
ATCTATGATG TGGTGGACGC CTCGGTCAAA CACTCCTGTA ACAGCAAACG CAGGAGCCTG
AGGGTCAAAC TGAGCGTCAC ACCAGAACCT GCAGCTCGCC GGAGAGACGC CACACACACT
GAAAGAGAAA CGAGTCATTT GAGTCAAGTT GAACCTGTTC GTTCAGAGGA GCATCGCAGC
GCAGACAGAC GACAGAGCAC ACACATCAGA GGCCAGACTG AGGCTCATGA GGGAAATCAT
TACTGCGTGG ATGAAAACAC AGAGAGACGA AATCATTACC TGGATCTGGC AGGAATAGAG
AACTACACGT CTAGATTTGA CAGTTCATCT CCGGATGCTG ATCAGGATCC CCCGTCTCGC
TCTTCACACA GTCAAAGTCG CCCCCATTCA CAGGAGCCCG AAACACATGT TTATCAGCGC
CGCTCACAGC TTATGGAGCC CTGTGTGGCC CCGGACCCCC GCCTGCGCAC CGGCCCCCAG
CTCATCAGAT CAAGATCCCC TAAAGGGTCG TCCAGATATC CTGGTGTCAT CCCGAATGTG
ACCAAAACCA GCAAGTGCCA CGGACACCAT CAGCCCATAT CGGCTGGTCA GGACGTTTAT
CATCTAACCC AGCAGAGCCA CACACACGCA CACACCCCGA GCGGCCTCCA GCACAGCCAC
AGCAGGAGGA TCAGATCCAG AGCCCGAGAA CAGCAGGCCC TGACACCGGT CAAAAACACC
AACGCTACTG CACTGGTCCA GAGACACGAA CACCATCACC ATCACGAACA CCACCATCAT
CACCACTACC ACCACTACCA CCAGACATGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
The Nkd EF-hand domain modulates divergent wnt signaling outputs in zebrafish.
Developmental biology434(1)63-73(2018 02)
Marsden AN,Derry SW,Schneider I,Scott CA,Westfall TA,Brastrom LK,Shea MA,Dawson DV,Slusarski DC
Deletion of Pr72 causes cardiac developmental defects in Zebrafish.
PloS one13(11)e0206883(2018)
Song G,Han M,Li Z,Gan X,Chen X,Yang J,Dong S,Yan M,Wan J,Wang Y,Huang Z,Yin Z,Zheng F
Rnf25/AO7 positively regulates wnt signaling via disrupting Nkd1-Axin inhibitory complex independent of its ubiquitin ligase activity.
Oncotarget7(17)23850-9(2016 Apr)
Gao R,Ma LQ,Du X,Zhang TT,Zhao L,Liu L,Liu JC,Guo F,Cheng Z,Huang H
RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R
Zebrafish Nkd1 promotes Dvl degradation and is required for left-right patterning.
Developmental biology348(1)22-33(2010 Dec)
Schneider I,Schneider PN,Derry SW,Lin S,Barton LJ,Westfall T,Slusarski DC
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