CNGB1 cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	CNGB1
Entrez Gene ID	102156683
Full Name	cyclic nucleotide gated channel beta 1
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001284462.1	NP_001271391.1	cyclic nucleotide-gated cation channel beta-1
XM_022405172.1	XP_022260880.1	cyclic nucleotide-gated cation channel beta-1 isoform X1

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	CNGB1	XP_001231878.3
Caenorhabditis elegans (roundworm)	tax-2	NP_492427.3
Homo sapiens (human)	CNGB1	NP_001273059.1
Macaca mulatta (Rhesus monkey)	CNGB1	XP_001100587.2
Pan troglodytes (chimpanzee)	CNGB1	XP_510998.3
Bos taurus (cattle)	CNGB1	NP_851362.1
Rattus norvegicus (Norway rat)	Cngb1	NP_113997.1
Canis lupus familiaris (dog)	CNGB1	XP_005617564.1

Gene Ontology
Bibliography

Related articles in PubMed

Patients and animal models of CNGβ1-deficient retinitis pigmentosa support gene augmentation approach.
Petersen-Jones SM, Occelli LM, Winkler PA, Lee W, Sparrow JR, Tsukikawa M, Boye SL, Chiodo V, Capasso JE, Becirovic E, Schön C, Seeliger MW, Levin AV, Michalakis S, Hauswirth WW, Tsang SH
The Journal of clinical investigation128(1)190-206(2018 01)

A large animal model for CNGB1 autosomal recessive retinitis pigmentosa.
Winkler PA, Ekenstedt KJ, Occelli LM, Frattaroli AV, Bartoe JT, Venta PJ, Petersen-Jones SM
PloS one8(8)e72229(2013)

A CNGB1 frameshift mutation in Papillon and Phalène dogs with progressive retinal atrophy.
Ahonen SJ, Arumilli M, Lohi H
PloS one8(8)e72122(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following CNGB1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CNGB1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OCe00370	NM_001284462.1 Latest version!	Canis lupus familiaris cyclic nucleotide gated channel subunit beta 1 (CNGB1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00
OCe286515	XM_022405172.1 Latest version!	Canis lupus familiaris cyclic nucleotide gated channel beta 1 (CNGB1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CNGB1 ( NM_001284462.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001271391.1 Canis lupus familiaris cyclic nucleotide gated channel subunit beta 1 (CNGB1), mRNA.

Price & Availability↑

CloneID	OCe00370
Clone ID Related Accession (Same CDS sequence)	NM_001284462.1
Accession Version	NM_001284462.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3630bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1560873600000
Organism	Canis lupus familiaris(dog)
Product	cyclic nucleotide-gated cation channel beta-1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from KC527595.1. On Oct 1, 2013 this sequence version replaced XM_005617507.1. ##Evidence-Data-START## Transcript exon combination :: KC527595.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA103936001, SAMEA2240594 [ECO:0000350] ##Evidence-Data-END##

ATGTTGAGCT GGGTCCAGAG GGTGCTGCCT CAGCCCCCAG GGACCCCTCA GAAGACCAAG 
GTAGAGGAGG AGGGAGGCGC AGACCCAGAG CCAGAGCCAG AGCCAGAGGT GAAGCAGGAA 
CCAGAGCTGG AGCCTGAAAC AGCCCTTGAG AAGGCCGAGC AAGGGGACTC CCTGCCACCT 
GAAGAGCCAT TGGAGGAAGT GGCTGCAGCT GACCCAGGCC CTCAGGAAAT CCAGGAGGCT 
GCCCTGAGTC CGCCTACATC CCTCCAGGCC CAGATCACTG TGGCTCCTGA AGTGAACAGC 
AGTTCCAACG ACTGGGTGCT GACATGGCTT AAGAAGAGCG TGGAGAAGGT GGTCCCACAG 
CCTGTCCCCA GCAGCAGGCT GGCCCAGAGC ACCGCTGCTG GCGGGGAGGG CCCTGCTCAG 
GCAGGAGCAC AGGTGTCTGG GCAATGCAGC ACTGGGAGCT CAGATGGACT TGGTGAGGCT 
GCTGGGGACA CCGGGTCTGG GCCCTGGCTG CTCAGGTGGC TTGAGCAGAA TCTGGAGAAA 
GTTCTGCCTC AACCTCCCAA AACCTCCAAG GACCAGAGAG ATGAACCTGC AGATGCTGCC 
TTGGACACAG AGCCCCCTGG GCCCACCCTG GAAACAGAGC CCGTGCTGCA GGCCCCAGAG 
AGCTCCTGCG TGCCCACTGC TGGCCCCTTG GAGCCCCAGG AGGAGCCGCC TTCAGAGCCC 
CAGCTCAGCC CTCAGGCTTC CTCCTTGCTG CTCCCCAGTG ACCCTGCCAG GTTGATGGCT 
TGGCTCCTGC ACAGGCTGGA GATGGCCCTG CCGCAGCCGG TGCTCCATGG GAAGGCCAGG 
GAGCAGGAGC CTGACTCCCC TGTGACCTGT GACGTGCAGA CCATCTGCAT CCTCCCTGGA 
GGCCAAGAGG AGCCCGATCT CGTCCTAGAA GAGGTTGACC CCCACTGGGA GGAGGATGAG 
CATCAGGATG GTGGCGCCAG CCCACAGGAC TCAGAGGCAG CTCCAGCTTA TGAAGAGGAG 
AATGAGGCTG TAGAGGAGAT GCCCAGGAAG CTGCCCTGGA TTCAAGAGGA GAGAGAAGAT 
GAGGAGGAGG ATGGAGAGGA GGAGGGAGAA GATGAGGAGG AGGCAAATGT CCTGCTGGAT 
AGCTGTCTGG AGGCGCAGGC TGGCGAGGAC CTGACTGGAG TAGACAGAAG CCAGCCCCAG 
AGGGCCTCCC AGCAGGAGCT GCAGGAGGAG GCCGTGACCA CCAGCCCAGA AGTGCCTGCT 
ACAAAAGAGC ACCCGGAAGT GCAGGTGGAA GATGTTGATG CGGACAGCCA TCCCCTGATC 
GTGGAAAATA CCCCCTCACC TGAGCTGCCA CCACCTTCTC CTGCCAAAGC CGACACCCTC 
ACGGTCCCAG GATCTGCCGC AGGAACAGAA AGGAAGAGGC TGCCCTCCCA AGATGATGAG 
GCTGAAGAGC TCAGGGCACT GTCACCAGCT GAGTCCCCCA TGGTCGCCTG GTCAGACCCA 
TCCAGCCCAC AAGGCACTGA TGGCCAGGAT CGCGCAACCT CCACGGCCAG CCAGAACAGC 
GCCATCATCA ATGACCGGCT CCAGGAGCTG GTGAAGCTTT TCAAGGAGCG GACGGAGAAA 
GTGAAGGAGA AGCTCATCGA CCCTGATGTC ACCTCCGATG AGGAGAGCCC AAAGCCCTCC 
CCGGCCAAGA AAGCCCCAGA GCCTGCCCCA GTCGTGAAGC CGGCTGAGGT GGGGCAGGCG 
GAGGAGGAGG AGCACTATTG TGACATGCTC TGCTGCAAGT TCAAGCGCCG CCCCTGGAAG 
ACGTACCGCT TTCCCCAGAG CATCGACCCG CTGACCAACC TGATGTACAT CCTGTGGCTG 
TTCTTTGTGG TGCTGGCGTG GAACTGGAAC TGTTGGCTGA TCCCCGTGCG CTGGGCCTTC 
CCTTACCAGA CACCAAACAA CATCCACCTC TGGCTGCTGA TGGATTATCT ATGTGATCTC 
ATCTACCTCC TGGACATCAC CGTGTTCCAG CTGCGCCTGC AGTTTGTCAG AGGGGGAGAC 
ATCATTACAG ACAAAAAGGA GATGCGGGAC AACTACCTGA AATCTCGTCG CTTTAAGATG 
GACATGCTCT GCCTCCTGCC CTTGGACTTC CTGTATTTGA AGTTTGGCGT GAATCCCCTC 
CTGCGCTTGC CCCGCTGTTT GAAGTACATG GCCTTCTTCG AATTTAACAG CCGCCTGGAA 
TCCATCCTCA GCAAAGCCTA TGTTTACAGG GTCATCAGGA CCACGGCCTA CCTGCTCTAC 
AGTCTGCATG TCAACTCCTG TCTGTATTAC TGGGCATCTG CCTATCAGGG CCTCGGCTCC 
ACTCACTGGG TTTACGATGG TGTGGGAAAC AGTTACATTC GCTGTTACTA CTGGGCTGTG 
AAGACCCTCA TCACCATTGG TGGGCTGCCT GACCCCAGAA CGCTCTTTGA AATTGTCTTC 
CAGGGGCTGA ACTATTTCAC GGGTGTCTTT GCTTTCTCTG TGATGATCGG ACAGATGAGA 
GACGTGGTGG GGGCCGCCAC CGCCGGGCAG ACCTACTACC GCAGCTGCAT GGACAGCACA 
GTGAAGTACA TGAATTTCTA CAAGATCCCC AGGTCCGTGC AGAACCGTGT CAAGACCTGG 
TACGAGTACA CCTGGCAGTC CCAAGGCATG CTGGACGAGT CAGAACTGAT GGTGCAGCTT 
CCAGACAAGA TGCGGTTGGA CCTCGCCATC GACGTGAACT ATAACATTGT CAGCAAAGTG 
GCTCTCTTCC AGGGCTGTGA CCGGCAGTTG ATCTTTGACA TGCTGAAGAG GCTTCGTTCT 
GTCGTCTATC TGCCCAACGA CTACGTGTGC AAGAAGGGGG AGATAGGCCG AGAGATGTAC 
ATTATAAAGG CAGGAGAGGT GCAGGTGTTG GGCGGCCCCG ATGGGAAGGC TGTGCTGGTG 
ACGCTGAAAG CTGGATCTGT GTTTGGAGAA ATAAGCTTAC TGGCTGTTGG GGGCGGGAAT 
CGGCGCACAG CCAATGTGGT CGCCCACGGG TTTACCAACC TCTTCATTCT GGATAAGAAG 
GACCTGAATG AAATTTTGGT GCATTATCCT GAGTCTCAGA AGTTACTCCG GAAGAAGGCC 
AGGCGCATGC TGAGAAATAA CAACAAGCCC AAGGAGCCGA AGAGCGTGCT CATCCTTCCT 
CCCCGGGCAG GCACCCCCAA GCTCTTCAAT GCTGCCCTGG CCGTAGCAGG AAAGATGGGC 
GCCAAGGGAG CCAAAGCCGG TAAACTTGCC CACCTGAGGG CTCGGCTCAA AGAACTGGCT 
GCACTGGAGG CAGCTGCGAG GCAGCAACAG TTGCTGGAAC AGGCCAAGAG CTCGCAGGAT 
GCTGCAGGAG AGGCAGGACA GGCGGCCCCA GACCAGGACC AGCCCCCAGC GCCCGAGCAC 
CCAGAATCCC AGGAGCCCCC GGCCACACGC TCTTCGCCAC CTGCCTCGCC ACCTGCCTCG 
CCACCTGCCT CGGAGAGGCC CGAGGAAGGC GGGGAGGGGG AGGCCGGGCC CTCAGAGCCA 
TCGGTGCTGA TCCGCATGAG CCCGGGCCCG GATCCCAGTG AACAGATCCT GTCGGTAGAG 
GTCCCGGAGG AGAAGAAAGA GGCCGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001271391.1
CDS	62..3691
Translation	MLSWVQRVLPQPPGTPQKTKVEEEGGADPEPEPEPEVKQEPELEPETALEKAEQGDSLPPEEPLEEVAAADPGPQEIQEAALSPPTSLQAQITVAPEVNSSSNDWVLTWLKKSVEKVVPQPVPSSRLAQSTAAGGEGPAQAGAQVSGQCSTGSSDGLGEAAGDTGSGPWLLRWLEQNLEKVLPQPPKTSKDQRDEPADAALDTEPPGPTLETEPVLQAPESSCVPTAGPLEPQEEPPSEPQLSPQASSLLLPSDPARLMAWLLHRLEMALPQPVLHGKAREQEPDSPVTCDVQTICILPGGQEEPDLVLEEVDPHWEEDEHQDGGASPQDSEAAPAYEEENEAVEEMPRKLPWIQEEREDEEEDGEEEGEDEEEANVLLDSCLEAQAGEDLTGVDRSQPQRASQQELQEEAVTTSPEVPATKEHPEVQVEDVDADSHPLIVENTPSPELPPPSPAKADTLTVPGSAAGTERKRLPSQDDEAEELRALSPAESPMVAWSDPSSPQGTDGQDRATSTASQNSAIINDRLQELVKLFKERTEKVKEKLIDPDVTSDEESPKPSPAKKAPEPAPVVKPAEVGQAEEEEHYCDMLCCKFKRRPWKTYRFPQSIDPLTNLMYILWLFFVVLAWNWNCWLIPVRWAFPYQTPNNIHLWLLMDYLCDLIYLLDITVFQLRLQFVRGGDIITDKKEMRDNYLKSRRFKMDMLCLLPLDFLYLKFGVNPLLRLPRCLKYMAFFEFNSRLESILSKAYVYRVIRTTAYLLYSLHVNSCLYYWASAYQGLGSTHWVYDGVGNSYIRCYYWAVKTLITIGGLPDPRTLFEIVFQGLNYFTGVFAFSVMIGQMRDVVGAATAGQTYYRSCMDSTVKYMNFYKIPRSVQNRVKTWYEYTWQSQGMLDESELMVQLPDKMRLDLAIDVNYNIVSKVALFQGCDRQLIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIKAGEVQVLGGPDGKAVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTNLFILDKKDLNEILVHYPESQKLLRKKARRMLRNNNKPKEPKSVLILPPRAGTPKLFNAALAVAGKMGAKGAKAGKLAHLRARLKELAALEAAARQQQLLEQAKSSQDAAGEAGQAAPDQDQPPAPEHPESQEPPATRSSPPASPPASPPASERPEEGGEGEAGPSEPSVLIRMSPGPDPSEQILSVEVPEEKKEAE

Target ORF information:

RefSeq Version	NM_001284462.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris cyclic nucleotide gated channel subunit beta 1 (CNGB1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001284462.1

ORF Insert Sequence:

ATGTTGAGCT GGGTCCAGAG GGTGCTGCCT CAGCCCCCAG GGACCCCTCA GAAGACCAAG 
GTAGAGGAGG AGGGAGGCGC AGACCCAGAG CCAGAGCCAG AGCCAGAGGT GAAGCAGGAA 
CCAGAGCTGG AGCCTGAAAC AGCCCTTGAG AAGGCCGAGC AAGGGGACTC CCTGCCACCT 
GAAGAGCCAT TGGAGGAAGT GGCTGCAGCT GACCCAGGCC CTCAGGAAAT CCAGGAGGCT 
GCCCTGAGTC CGCCTACATC CCTCCAGGCC CAGATCACTG TGGCTCCTGA AGTGAACAGC 
AGTTCCAACG ACTGGGTGCT GACATGGCTT AAGAAGAGCG TGGAGAAGGT GGTCCCACAG 
CCTGTCCCCA GCAGCAGGCT GGCCCAGAGC ACCGCTGCTG GCGGGGAGGG CCCTGCTCAG 
GCAGGAGCAC AGGTGTCTGG GCAATGCAGC ACTGGGAGCT CAGATGGACT TGGTGAGGCT 
GCTGGGGACA CCGGGTCTGG GCCCTGGCTG CTCAGGTGGC TTGAGCAGAA TCTGGAGAAA 
GTTCTGCCTC AACCTCCCAA AACCTCCAAG GACCAGAGAG ATGAACCTGC AGATGCTGCC 
TTGGACACAG AGCCCCCTGG GCCCACCCTG GAAACAGAGC CCGTGCTGCA GGCCCCAGAG 
AGCTCCTGCG TGCCCACTGC TGGCCCCTTG GAGCCCCAGG AGGAGCCGCC TTCAGAGCCC 
CAGCTCAGCC CTCAGGCTTC CTCCTTGCTG CTCCCCAGTG ACCCTGCCAG GTTGATGGCT 
TGGCTCCTGC ACAGGCTGGA GATGGCCCTG CCGCAGCCGG TGCTCCATGG GAAGGCCAGG 
GAGCAGGAGC CTGACTCCCC TGTGACCTGT GACGTGCAGA CCATCTGCAT CCTCCCTGGA 
GGCCAAGAGG AGCCCGATCT CGTCCTAGAA GAGGTTGACC CCCACTGGGA GGAGGATGAG 
CATCAGGATG GTGGCGCCAG CCCACAGGAC TCAGAGGCAG CTCCAGCTTA TGAAGAGGAG 
AATGAGGCTG TAGAGGAGAT GCCCAGGAAG CTGCCCTGGA TTCAAGAGGA GAGAGAAGAT 
GAGGAGGAGG ATGGAGAGGA GGAGGGAGAA GATGAGGAGG AGGCAAATGT CCTGCTGGAT 
AGCTGTCTGG AGGCGCAGGC TGGCGAGGAC CTGACTGGAG TAGACAGAAG CCAGCCCCAG 
AGGGCCTCCC AGCAGGAGCT GCAGGAGGAG GCCGTGACCA CCAGCCCAGA AGTGCCTGCT 
ACAAAAGAGC ACCCGGAAGT GCAGGTGGAA GATGTTGATG CGGACAGCCA TCCCCTGATC 
GTGGAAAATA CCCCCTCACC TGAGCTGCCA CCACCTTCTC CTGCCAAAGC CGACACCCTC 
ACGGTCCCAG GATCTGCCGC AGGAACAGAA AGGAAGAGGC TGCCCTCCCA AGATGATGAG 
GCTGAAGAGC TCAGGGCACT GTCACCAGCT GAGTCCCCCA TGGTCGCCTG GTCAGACCCA 
TCCAGCCCAC AAGGCACTGA TGGCCAGGAT CGCGCAACCT CCACGGCCAG CCAGAACAGC 
GCCATCATCA ATGACCGGCT CCAGGAGCTG GTGAAGCTTT TCAAGGAGCG GACGGAGAAA 
GTGAAGGAGA AGCTCATCGA CCCTGATGTC ACCTCCGATG AGGAGAGCCC AAAGCCCTCC 
CCGGCCAAGA AAGCCCCAGA GCCTGCCCCA GTCGTGAAGC CGGCTGAGGT GGGGCAGGCG 
GAGGAGGAGG AGCACTATTG TGACATGCTC TGCTGCAAGT TCAAGCGCCG CCCCTGGAAG 
ACGTACCGCT TTCCCCAGAG CATCGACCCG CTGACCAACC TGATGTACAT CCTGTGGCTG 
TTCTTTGTGG TGCTGGCGTG GAACTGGAAC TGTTGGCTGA TCCCCGTGCG CTGGGCCTTC 
CCTTACCAGA CACCAAACAA CATCCACCTC TGGCTGCTGA TGGATTATCT ATGTGATCTC 
ATCTACCTCC TGGACATCAC CGTGTTCCAG CTGCGCCTGC AGTTTGTCAG AGGGGGAGAC 
ATCATTACAG ACAAAAAGGA GATGCGGGAC AACTACCTGA AATCTCGTCG CTTTAAGATG 
GACATGCTCT GCCTCCTGCC CTTGGACTTC CTGTATTTGA AGTTTGGCGT GAATCCCCTC 
CTGCGCTTGC CCCGCTGTTT GAAGTACATG GCCTTCTTCG AATTTAACAG CCGCCTGGAA 
TCCATCCTCA GCAAAGCCTA TGTTTACAGG GTCATCAGGA CCACGGCCTA CCTGCTCTAC 
AGTCTGCATG TCAACTCCTG TCTGTATTAC TGGGCATCTG CCTATCAGGG CCTCGGCTCC 
ACTCACTGGG TTTACGATGG TGTGGGAAAC AGTTACATTC GCTGTTACTA CTGGGCTGTG 
AAGACCCTCA TCACCATTGG TGGGCTGCCT GACCCCAGAA CGCTCTTTGA AATTGTCTTC 
CAGGGGCTGA ACTATTTCAC GGGTGTCTTT GCTTTCTCTG TGATGATCGG ACAGATGAGA 
GACGTGGTGG GGGCCGCCAC CGCCGGGCAG ACCTACTACC GCAGCTGCAT GGACAGCACA 
GTGAAGTACA TGAATTTCTA CAAGATCCCC AGGTCCGTGC AGAACCGTGT CAAGACCTGG 
TACGAGTACA CCTGGCAGTC CCAAGGCATG CTGGACGAGT CAGAACTGAT GGTGCAGCTT 
CCAGACAAGA TGCGGTTGGA CCTCGCCATC GACGTGAACT ATAACATTGT CAGCAAAGTG 
GCTCTCTTCC AGGGCTGTGA CCGGCAGTTG ATCTTTGACA TGCTGAAGAG GCTTCGTTCT 
GTCGTCTATC TGCCCAACGA CTACGTGTGC AAGAAGGGGG AGATAGGCCG AGAGATGTAC 
ATTATAAAGG CAGGAGAGGT GCAGGTGTTG GGCGGCCCCG ATGGGAAGGC TGTGCTGGTG 
ACGCTGAAAG CTGGATCTGT GTTTGGAGAA ATAAGCTTAC TGGCTGTTGG GGGCGGGAAT 
CGGCGCACAG CCAATGTGGT CGCCCACGGG TTTACCAACC TCTTCATTCT GGATAAGAAG 
GACCTGAATG AAATTTTGGT GCATTATCCT GAGTCTCAGA AGTTACTCCG GAAGAAGGCC 
AGGCGCATGC TGAGAAATAA CAACAAGCCC AAGGAGCCGA AGAGCGTGCT CATCCTTCCT 
CCCCGGGCAG GCACCCCCAA GCTCTTCAAT GCTGCCCTGG CCGTAGCAGG AAAGATGGGC 
GCCAAGGGAG CCAAAGCCGG TAAACTTGCC CACCTGAGGG CTCGGCTCAA AGAACTGGCT 
GCACTGGAGG CAGCTGCGAG GCAGCAACAG TTGCTGGAAC AGGCCAAGAG CTCGCAGGAT 
GCTGCAGGAG AGGCAGGACA GGCGGCCCCA GACCAGGACC AGCCCCCAGC GCCCGAGCAC 
CCAGAATCCC AGGAGCCCCC GGCCACACGC TCTTCGCCAC CTGCCTCGCC ACCTGCCTCG 
CCACCTGCCT CGGAGAGGCC CGAGGAAGGC GGGGAGGGGG AGGCCGGGCC CTCAGAGCCA 
TCGGTGCTGA TCCGCATGAG CCCGGGCCCG GATCCCAGTG AACAGATCCT GTCGGTAGAG 
GTCCCGGAGG AGAAGAAAGA GGCCGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CNGB1 ( XM_022405172.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_022260880.1 Canis lupus familiaris cyclic nucleotide gated channel beta 1 (CNGB1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe286515
Clone ID Related Accession (Same CDS sequence)	XM_022405172.1
Accession Version	XM_022405172.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3630bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1504454400000
Organism	Canis lupus familiaris(dog)
Product	cyclic nucleotide-gated cation channel beta-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006584.3) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGAGCT GGGTCCAGAG GGTGCTGCCT CAGCCCCCAG GGACCCCTCA GAAGACCAAG 
GTAGAGGAGG AGGGAGGCGC AGACCCAGAG CCAGAGCCAG AGCCAGAGGT GAAGCAGGAA 
CCAGAGCTGG AGCCTGAAAC AGCCCTTGAG GAGGCCGAGC AAGGGGACTC CCTGCCACCT 
GAAGAGCCAT TGGAGGAAGT GGCTGCAGCT GACCCAGGCC CTCAGGAAAT CCAGGAGGCT 
GCCCTGAGTC CGCCTACATC CCTCCAGGCC CAGATCACTG TGGCTCCTGA AGTGAACAGC 
AGTTCCAACG ACTGGGTGCT GACATGGCTT AAGAAGAGCG TGGAGAAGGT GGTCCCACAG 
CCTGTCCCCA GCAGCAGGCT GGCCCAGAGC ACCGCTGCTG GCGGGGAGGG CCCTGCTCAG 
GCAGGAGCAC AGGTGTCTGG GCAATGCAGC ACTGGGAGCT CAGATGGACT TGGTGAGGCT 
GCTGGGGACA CCGGGTCTGG GCCCTGGCTG CTCAGGTGGC TTGAGCAGAA TCTGGAGAAA 
GTTCTGCCTC AACCTCCCAA AACCTCCAAG GACCAGAGAG ATGAACCTGC AGATGCTGCC 
TTGGACACAG AGCCCCCTGG GCCCACCCTG GAAACAGAGC CCGTGCTGCA GGCCCCAGAG 
AGCTCCTGCG TGCCCACTGC TGGCCCCTTG GAGCCCCAGG AGGAGCCGCC TTCAGAGCCC 
CAGCTCAGCC CTCAGGCTTC CTCCTTGCTG CTCCCCAGTG ACCCTGCCAG GTTGATGGCT 
TGGCTCCTGC ACAGGCTGGA GATGGCCCTG CCGCAGCCGG TGCTCCATGG GAAGGCCAGG 
GAGCAGGAGC CTGACTCCCC TGTGACCTGT GACGTGCAGA CCATCTGCAT CCTCCCTGGA 
GGCCAAGAGG AGCCCGATCT CGTCCTAGAA GAGGTTGACC CCCACTGGGA GGAGGATGAG 
CATCAGGATG GTGGCGCCAG CCCACAGGAC TCAGAGGCAG CTCCAGCTTA TGAAGAGGAG 
AATGAGGCTG TAGAGGAGAT GCCCAGGAAG CTGCCCTGGA TTCAAGAGGA GAGAGAAGAT 
GAGGAGGAGG ATGGAGAGGA GGAGGGAGAA GATGAGGAGG AGGCAAATGT CCTGCTGGAT 
AGCTGTCTGG AGGCGCAGGC TGGCGAGGAC CTGACTGGAG TAGACAGAAG CCAGCCCCAG 
AGGGCCTCCC AGCAGGAGCT GCAGGAGGAG GCCGTGACCA CCAGCCCAGA AGTGCCTGCT 
ACAAAAGAGC ACCCGGAAGT GCAGGTGGAA GATGTTGATG CGGACAGCCA TCCCCTGATC 
GTGGAAAATA CCCCCTCACC TGAGCTGCCA CCACCTTCTC CTGCCAAAGC CGACACCCTC 
ACGGTCCCAG GATCTGCCGC AGGAACAGAA AGGAAGAGGC TGCCCTCCCA AGATGATGAG 
GCTGAAGAGC TCAGGGCACT GTCACCAGCT GAGTCCCCCA TGGTCGCCTG GTCAGACCCA 
TCCAGCCCAC AAGGCACTGA TGGCCAGGAT CGCGCAACCT CCACGGCCAG CCAGAACAGC 
GCCATCATCA ATGACCGGCT CCAGGAGCTG GTGAAGCTTT TCAAGGAGCG GACGGAGAAA 
GTGAAGGAGA AGCTCATCGA CCCTGATGTC ACCTCCGATG AGGAGAGCCC AAAGCCCTCC 
CCGGCCAAGA AAGCCCCAGA GCCTGCCCCA GTCGTGAAGC CGGCTGAGGT GGGGCAGGCG 
GAGGAGGAGG AGCACTATTG TGACATGCTC TGCTGCAAGT TCAAGCGCCG CCCCTGGAAG 
ACGTACCGCT TTCCCCAGAG CATCGACCCG CTGACCAACC TGATGTACAT CCTGTGGCTG 
TTCTTTGTGG TGCTGGCGTG GAACTGGAAC TGTTGGCTGA TCCCCGTGCG CTGGGCCTTC 
CCTTACCAGA CACCAAACAA CATCCACCTC TGGCTGCTGA TGGATTATCT ATGTGATCTC 
ATCTACCTCC TGGACATCAC CGTGTTCCAG CTGCGCCTGC AGTTTGTCAG AGGGGGAGAC 
ATCATTACAG ACAAAAAGGA GATGCGGGAC AACTACCTGA AATCTCGTCG CTTTAAGATG 
GACATGCTCT GCCTCCTGCC CTTGGACTTC CTGTATTTGA AGTTTGGCGT GAATCCCCTC 
CTGCGCTTGC CCCGCTGTTT GAAGTACATG GCCTTCTTCG AATTTAACAG CCGCCTGGAA 
TCCATCCTCA GCAAAGCCTA TGTTTACAGG GTCATCAGGA CCACGGCCTA CCTGCTCTAC 
AGTCTGCATG TCAACTCCTG TCTGTATTAC TGGGCATCTG CCTATCAGGG CCTCGGCTCC 
ACTCACTGGG TTTACGATGG TGTGGGAAAC AGTTACATTC GCTGTTACTA CTGGGCTGTG 
AAGACCCTCA TCACCATTGG TGGGCTGCCT GACCCCAGAA CGCTCTTTGA AATTGTCTTC 
CAGGGGCTGA ACTATTTCAC GGGTGTCTTT GCTTTCTCTG TGATGATCGG ACAGATGAGA 
GACGTGGTGG GGGCCGCCAC CGCCGGGCAG ACCTACTACC GCAGCTGCAT GGACAGCACA 
GTGAAGTACA TGAATTTCTA CAAGATCCCC AGGTCCGTGC AGAACCGTGT CAAGACCTGG 
TACGAGTACA CCTGGCAGTC CCAAGGCATG CTGGACGAGT CAGAACTGAT GGTGCAGCTT 
CCAGACAAGA TGCGGTTGGA CCTCGCCATC GACGTGAACT ATAACATTGT CAGCAAAGTG 
GCTCTCTTCC AGGGCTGTGA CCGGCAGTTG ATCTTTGACA TGCTGAAGAG GCTTCGTTCT 
GTCGTCTATC TGCCCAACGA CTACGTGTGC AAGAAGGGGG AGATAGGCCG AGAGATGTAC 
ATTATAAAGG CAGGAGAGGT GCAGGTGTTG GGCGGCCCCG ATGGGAAGGC TGTGCTGGTG 
ACGCTGAAAG CTGGATCTGT GTTTGGAGAA ATAAGCTTAC TGGCTGTTGG GGGCGGGAAT 
CGGCGCACAG CCAATGTGGT CGCCCACGGG TTTACCAACC TCTTCATTCT GGATAAGAAG 
GACCTGAATG AAATTTTGGT GCATTATCCT GAGTCTCAGA AGTTACTCCG GAAGAAGGCC 
AGGCGCATGC TGAGAAATAA CAACAAGCCC AAGGAGCCGA AGAGCGTGCT CATCCTTCCT 
CCCCGGGCAG GCACCCCCAA GCTCTTCAAT GCTGCCCTGG CCGTAGCAGG AAAGATGGGC 
GCCAAGGGAG CCAAAGCCGG TAAACTTGCC CACCTGAGGG CTCGGCTCAA AGAACTGGCT 
GCACTGGAGG CAGCTGCGAG GCAGCAACAG TTGCTGGAAC AGGCCAAGAG CTCGCAGGAT 
GCTGCAGGAG AGGCAGGCCA GGCGGCCCCA GACCAGGACC AGCCCCCAGC GCCCGAGCAC 
CCAGAATCCC AGGAGCCCCT GGCCACACGC TCTTCGCCAC CTGCCTCGCC ACCTGCCTCG 
CCACCTGCCT CGGAGAGGCC CGAGGAAGGC GGGGAGGGGG AGGCCGGGCC CTCGGAGCCA 
TCGGTGCTGA TCCGCATGAG CCCGGGCCCG GATCCCAGTG AACAGATCCT GTCGGTAGAG 
GTCCCGGAGG AGAAGAAAGA GGCCGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_022260880.1
CDS	26..3655
Translation	MLSWVQRVLPQPPGTPQKTKVEEEGGADPEPEPEPEVKQEPELEPETALEEAEQGDSLPPEEPLEEVAAADPGPQEIQEAALSPPTSLQAQITVAPEVNSSSNDWVLTWLKKSVEKVVPQPVPSSRLAQSTAAGGEGPAQAGAQVSGQCSTGSSDGLGEAAGDTGSGPWLLRWLEQNLEKVLPQPPKTSKDQRDEPADAALDTEPPGPTLETEPVLQAPESSCVPTAGPLEPQEEPPSEPQLSPQASSLLLPSDPARLMAWLLHRLEMALPQPVLHGKAREQEPDSPVTCDVQTICILPGGQEEPDLVLEEVDPHWEEDEHQDGGASPQDSEAAPAYEEENEAVEEMPRKLPWIQEEREDEEEDGEEEGEDEEEANVLLDSCLEAQAGEDLTGVDRSQPQRASQQELQEEAVTTSPEVPATKEHPEVQVEDVDADSHPLIVENTPSPELPPPSPAKADTLTVPGSAAGTERKRLPSQDDEAEELRALSPAESPMVAWSDPSSPQGTDGQDRATSTASQNSAIINDRLQELVKLFKERTEKVKEKLIDPDVTSDEESPKPSPAKKAPEPAPVVKPAEVGQAEEEEHYCDMLCCKFKRRPWKTYRFPQSIDPLTNLMYILWLFFVVLAWNWNCWLIPVRWAFPYQTPNNIHLWLLMDYLCDLIYLLDITVFQLRLQFVRGGDIITDKKEMRDNYLKSRRFKMDMLCLLPLDFLYLKFGVNPLLRLPRCLKYMAFFEFNSRLESILSKAYVYRVIRTTAYLLYSLHVNSCLYYWASAYQGLGSTHWVYDGVGNSYIRCYYWAVKTLITIGGLPDPRTLFEIVFQGLNYFTGVFAFSVMIGQMRDVVGAATAGQTYYRSCMDSTVKYMNFYKIPRSVQNRVKTWYEYTWQSQGMLDESELMVQLPDKMRLDLAIDVNYNIVSKVALFQGCDRQLIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIKAGEVQVLGGPDGKAVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTNLFILDKKDLNEILVHYPESQKLLRKKARRMLRNNNKPKEPKSVLILPPRAGTPKLFNAALAVAGKMGAKGAKAGKLAHLRARLKELAALEAAARQQQLLEQAKSSQDAAGEAGQAAPDQDQPPAPEHPESQEPLATRSSPPASPPASPPASERPEEGGEGEAGPSEPSVLIRMSPGPDPSEQILSVEVPEEKKEAE

Target ORF information:

RefSeq Version	XM_022405172.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris cyclic nucleotide gated channel beta 1 (CNGB1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_022405172.1

ORF Insert Sequence:

ATGTTGAGCT GGGTCCAGAG GGTGCTGCCT CAGCCCCCAG GGACCCCTCA GAAGACCAAG 
GTAGAGGAGG AGGGAGGCGC AGACCCAGAG CCAGAGCCAG AGCCAGAGGT GAAGCAGGAA 
CCAGAGCTGG AGCCTGAAAC AGCCCTTGAG GAGGCCGAGC AAGGGGACTC CCTGCCACCT 
GAAGAGCCAT TGGAGGAAGT GGCTGCAGCT GACCCAGGCC CTCAGGAAAT CCAGGAGGCT 
GCCCTGAGTC CGCCTACATC CCTCCAGGCC CAGATCACTG TGGCTCCTGA AGTGAACAGC 
AGTTCCAACG ACTGGGTGCT GACATGGCTT AAGAAGAGCG TGGAGAAGGT GGTCCCACAG 
CCTGTCCCCA GCAGCAGGCT GGCCCAGAGC ACCGCTGCTG GCGGGGAGGG CCCTGCTCAG 
GCAGGAGCAC AGGTGTCTGG GCAATGCAGC ACTGGGAGCT CAGATGGACT TGGTGAGGCT 
GCTGGGGACA CCGGGTCTGG GCCCTGGCTG CTCAGGTGGC TTGAGCAGAA TCTGGAGAAA 
GTTCTGCCTC AACCTCCCAA AACCTCCAAG GACCAGAGAG ATGAACCTGC AGATGCTGCC 
TTGGACACAG AGCCCCCTGG GCCCACCCTG GAAACAGAGC CCGTGCTGCA GGCCCCAGAG 
AGCTCCTGCG TGCCCACTGC TGGCCCCTTG GAGCCCCAGG AGGAGCCGCC TTCAGAGCCC 
CAGCTCAGCC CTCAGGCTTC CTCCTTGCTG CTCCCCAGTG ACCCTGCCAG GTTGATGGCT 
TGGCTCCTGC ACAGGCTGGA GATGGCCCTG CCGCAGCCGG TGCTCCATGG GAAGGCCAGG 
GAGCAGGAGC CTGACTCCCC TGTGACCTGT GACGTGCAGA CCATCTGCAT CCTCCCTGGA 
GGCCAAGAGG AGCCCGATCT CGTCCTAGAA GAGGTTGACC CCCACTGGGA GGAGGATGAG 
CATCAGGATG GTGGCGCCAG CCCACAGGAC TCAGAGGCAG CTCCAGCTTA TGAAGAGGAG 
AATGAGGCTG TAGAGGAGAT GCCCAGGAAG CTGCCCTGGA TTCAAGAGGA GAGAGAAGAT 
GAGGAGGAGG ATGGAGAGGA GGAGGGAGAA GATGAGGAGG AGGCAAATGT CCTGCTGGAT 
AGCTGTCTGG AGGCGCAGGC TGGCGAGGAC CTGACTGGAG TAGACAGAAG CCAGCCCCAG 
AGGGCCTCCC AGCAGGAGCT GCAGGAGGAG GCCGTGACCA CCAGCCCAGA AGTGCCTGCT 
ACAAAAGAGC ACCCGGAAGT GCAGGTGGAA GATGTTGATG CGGACAGCCA TCCCCTGATC 
GTGGAAAATA CCCCCTCACC TGAGCTGCCA CCACCTTCTC CTGCCAAAGC CGACACCCTC 
ACGGTCCCAG GATCTGCCGC AGGAACAGAA AGGAAGAGGC TGCCCTCCCA AGATGATGAG 
GCTGAAGAGC TCAGGGCACT GTCACCAGCT GAGTCCCCCA TGGTCGCCTG GTCAGACCCA 
TCCAGCCCAC AAGGCACTGA TGGCCAGGAT CGCGCAACCT CCACGGCCAG CCAGAACAGC 
GCCATCATCA ATGACCGGCT CCAGGAGCTG GTGAAGCTTT TCAAGGAGCG GACGGAGAAA 
GTGAAGGAGA AGCTCATCGA CCCTGATGTC ACCTCCGATG AGGAGAGCCC AAAGCCCTCC 
CCGGCCAAGA AAGCCCCAGA GCCTGCCCCA GTCGTGAAGC CGGCTGAGGT GGGGCAGGCG 
GAGGAGGAGG AGCACTATTG TGACATGCTC TGCTGCAAGT TCAAGCGCCG CCCCTGGAAG 
ACGTACCGCT TTCCCCAGAG CATCGACCCG CTGACCAACC TGATGTACAT CCTGTGGCTG 
TTCTTTGTGG TGCTGGCGTG GAACTGGAAC TGTTGGCTGA TCCCCGTGCG CTGGGCCTTC 
CCTTACCAGA CACCAAACAA CATCCACCTC TGGCTGCTGA TGGATTATCT ATGTGATCTC 
ATCTACCTCC TGGACATCAC CGTGTTCCAG CTGCGCCTGC AGTTTGTCAG AGGGGGAGAC 
ATCATTACAG ACAAAAAGGA GATGCGGGAC AACTACCTGA AATCTCGTCG CTTTAAGATG 
GACATGCTCT GCCTCCTGCC CTTGGACTTC CTGTATTTGA AGTTTGGCGT GAATCCCCTC 
CTGCGCTTGC CCCGCTGTTT GAAGTACATG GCCTTCTTCG AATTTAACAG CCGCCTGGAA 
TCCATCCTCA GCAAAGCCTA TGTTTACAGG GTCATCAGGA CCACGGCCTA CCTGCTCTAC 
AGTCTGCATG TCAACTCCTG TCTGTATTAC TGGGCATCTG CCTATCAGGG CCTCGGCTCC 
ACTCACTGGG TTTACGATGG TGTGGGAAAC AGTTACATTC GCTGTTACTA CTGGGCTGTG 
AAGACCCTCA TCACCATTGG TGGGCTGCCT GACCCCAGAA CGCTCTTTGA AATTGTCTTC 
CAGGGGCTGA ACTATTTCAC GGGTGTCTTT GCTTTCTCTG TGATGATCGG ACAGATGAGA 
GACGTGGTGG GGGCCGCCAC CGCCGGGCAG ACCTACTACC GCAGCTGCAT GGACAGCACA 
GTGAAGTACA TGAATTTCTA CAAGATCCCC AGGTCCGTGC AGAACCGTGT CAAGACCTGG 
TACGAGTACA CCTGGCAGTC CCAAGGCATG CTGGACGAGT CAGAACTGAT GGTGCAGCTT 
CCAGACAAGA TGCGGTTGGA CCTCGCCATC GACGTGAACT ATAACATTGT CAGCAAAGTG 
GCTCTCTTCC AGGGCTGTGA CCGGCAGTTG ATCTTTGACA TGCTGAAGAG GCTTCGTTCT 
GTCGTCTATC TGCCCAACGA CTACGTGTGC AAGAAGGGGG AGATAGGCCG AGAGATGTAC 
ATTATAAAGG CAGGAGAGGT GCAGGTGTTG GGCGGCCCCG ATGGGAAGGC TGTGCTGGTG 
ACGCTGAAAG CTGGATCTGT GTTTGGAGAA ATAAGCTTAC TGGCTGTTGG GGGCGGGAAT 
CGGCGCACAG CCAATGTGGT CGCCCACGGG TTTACCAACC TCTTCATTCT GGATAAGAAG 
GACCTGAATG AAATTTTGGT GCATTATCCT GAGTCTCAGA AGTTACTCCG GAAGAAGGCC 
AGGCGCATGC TGAGAAATAA CAACAAGCCC AAGGAGCCGA AGAGCGTGCT CATCCTTCCT 
CCCCGGGCAG GCACCCCCAA GCTCTTCAAT GCTGCCCTGG CCGTAGCAGG AAAGATGGGC 
GCCAAGGGAG CCAAAGCCGG TAAACTTGCC CACCTGAGGG CTCGGCTCAA AGAACTGGCT 
GCACTGGAGG CAGCTGCGAG GCAGCAACAG TTGCTGGAAC AGGCCAAGAG CTCGCAGGAT 
GCTGCAGGAG AGGCAGGCCA GGCGGCCCCA GACCAGGACC AGCCCCCAGC GCCCGAGCAC 
CCAGAATCCC AGGAGCCCCT GGCCACACGC TCTTCGCCAC CTGCCTCGCC ACCTGCCTCG 
CCACCTGCCT CGGAGAGGCC CGAGGAAGGC GGGGAGGGGG AGGCCGGGCC CTCGGAGCCA 
TCGGTGCTGA TCCGCATGAG CCCGGGCCCG GATCCCAGTG AACAGATCCT GTCGGTAGAG 
GTCCCGGAGG AGAAGAAAGA GGCCGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Patients and animal models of CNGβ1-deficient retinitis pigmentosa support gene augmentation approach.
The Journal of clinical investigation128(1)190-206(2018 01)
Petersen-Jones SM,Occelli LM,Winkler PA,Lee W,Sparrow JR,Tsukikawa M,Boye SL,Chiodo V,Capasso JE,Becirovic E,Schön C,Seeliger MW,Levin AV,Michalakis S,Hauswirth WW,Tsang SH

A large animal model for CNGB1 autosomal recessive retinitis pigmentosa.
PloS one8(8)e72229(2013)
Winkler PA,Ekenstedt KJ,Occelli LM,Frattaroli AV,Bartoe JT,Venta PJ,Petersen-Jones SM

A CNGB1 frameshift mutation in Papillon and Phalène dogs with progressive retinal atrophy.
PloS one8(8)e72122(2013)
Ahonen SJ,Arumilli M,Lohi H

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CNGB1 cDNA ORF clone, Canis lupus familiaris(dog)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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