MYD88 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	MYD88
Entrez Gene ID	444881
Full Name	myeloid differentiation primary response 88
General protein information	Preferred Names myeloid differentiation primary response 88 Names myeloid differentiation primary response protein MyD88 myeloid differentiation factor 88 myeloid differentiation primary response gene (88)
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001014382.2	NP_001014404.1	myeloid differentiation primary response protein MyD88
XM_005222379.3	XP_005222436.1	myeloid differentiation primary response protein MyD88 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	MYD88	XP_534223.2
Rattus norvegicus (Norway rat)	Myd88	NP_937763.1
Mus musculus (house mouse)	Myd88	NP_034981.1
Danio rerio (zebrafish)	myd88	NP_997979.2
Xenopus tropicalis (tropical clawed frog)	myd88	NP_001016837.1
Homo sapiens (human)	MYD88	NP_002459.2
Pan troglodytes (chimpanzee)	MYD88	NP_001123935.1
Macaca mulatta (Rhesus monkey)	MYD88	NP_001124153.1
Bos taurus (cattle)	MYD88	NP_001014404.1
Gallus gallus (chicken)	MYD88	NP_001026133.1
Anopheles gambiae (African malaria mosquito)	MYD	XP_314167.4

Gene Ontology
Bibliography

Related articles in PubMed

Lactobacillus rhamnosus GR-1 Limits Escherichia coli-Induced Inflammatory Responses via Attenuating MyD88-Dependent and MyD88-Independent Pathway Activation in Bovine Endometrial Epithelial Cells.
Liu M, Wu Q, Wang M, Fu Y, Wang J
Inflammation39(4)1483-94(2016 Aug)

Mycoplasma bovis-derived lipid-associated membrane proteins activate IL-1β production through the NF-κB pathway via toll-like receptor 2 and MyD88.
Wang Y, Liu S, Li Y, Wang Q, Shao J, Chen Y, Xin J
Developmental and comparative immunology55111-8(2016 Feb)

Bovine viral diarrhea virus type 2 in vivo infection modulates TLR4 responsiveness in differentiated myeloid cells which is associated with decreased MyD88 expression.
Schaut RG, McGill JL, Neill JD, Ridpath JF, Sacco RE
Virus research20844-55(2015 Oct)

Heterozygosity at the A625C polymorphic site of the MyD88 gene is associated with Mycobacterium bovis infection in cattle.
Capparelli R, De Chiara F, Nocerino N, Medaglia C, Di Costanzo R, Ramunno L, Capuano F, Casalinuovo F, Di Matteo A, Iannelli D
Infection and immunity81(6)2139-44(2013 Jun)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Marçais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MYD88 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MYD88 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa43604	NM_001014382.2 Latest version!	Bos taurus MYD88 innate immune signal transduction adaptor (MYD88), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OBa31235	XM_005222379.3 Latest version!	Bos taurus myeloid differentiation primary response 88 (MYD88), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MYD88 ( NM_001014382.2 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001014404.1 Bos taurus MYD88 innate immune signal transduction adaptor (MYD88), mRNA.

Price & Availability↑

CloneID	OBa43604
Clone ID Related Accession (Same CDS sequence)	NM_001014382.2
Accession Version	NM_001014382.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 891bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577203200000
Organism	Bos taurus(cattle)
Product	myeloid differentiation primary response protein MyD88
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC102851.1. On Sep 18, 2005 this sequence version replaced NM_001014382.1. ##Evidence-Data-START## Transcript exon combination :: BC102851.1, AJ853453.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145412, SAMN03145413 [ECO:0000348] ##Evidence-Data-END##

ATGGCTGAAG GAGTACCCCG CGCGGGGTCC GCGCTCCCCG CGGCTTCCTT GTCCTCCCTG 
CCCCTGGCAG CGCTCAACGT ACGAGTGCGG CGCCGCCTGT CGCTCTTCCT AAACGTGCGG 
GCGCCGGTGG CGGCCGACTG GACCGTGCTG GCGGAGGCGA TGGACTTCGA GTACTTGGAG 
ATCCAGCAGC TGGAGAAGTA CGCCGACCCC ACGAGCAGGC TCCTGGACGA CTGGCAGCGA 
CGTCCGGGAG CCTCAGTGGG CCGCCTGCTC GAGCTGCTCG CCAAGCTCGG CCGCGACGAC 
GTGCTGATGG AACTGGGACC CAGCATCGAG GAGGACTGCC AAAAGTATAT TCTGAAGCAG 
CAGCAGGAGG CATCTGAGAA GCCTTTACAG GTGGACTCTA TAGACAGCAG CATAACTCGG 
ATAAATGACA TGGCAGGCAT CACCATTCGC GACGACCCCC TAGGGCAAAA GCCCGAGTGT 
TTTGATGCCT TCATCTGCTA CTGCCCCAGC GATATTGAGT TTGTCCACGA GATGATCCGG 
CAGCTGGAAC AGACAAACTA TCGGCTGAAG TTGTGCGTGT CTGACCGTGA CGTCCTGCCT 
GGCACCTGTG TCTGGTCCAT CGCCAGTGAA CTCATTGAGA AGAGGTGCCG TCGGATGGTG 
GTGGTGGTCT CTGACGAATA CCTGCAAAGC AAGGAATGTG ATTTCCAGAC TAAGTTTGCA 
CTCAGCCTCT CTCCAGGTGC CCATCAGAAG CGACTGATCC CCATCAAGTA CAAGCCAATG 
AAGAAAGAGT TCCCCAGCAT CCTGCGCTTC ATCACTGTCT GTGACTACAC CAACCCCTGC 
ACCCAGAACT GGTTCTGGAC TCGCCTCGCC AAGGCCCTGT CCATGCCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001014404.1
CDS	38..928
Translation	MAEGVPRAGSALPAASLSSLPLAALNVRVRRRLSLFLNVRAPVAADWTVLAEAMDFEYLEIQQLEKYADPTSRLLDDWQRRPGASVGRLLELLAKLGRDDVLMELGPSIEEDCQKYILKQQQEASEKPLQVDSIDSSITRINDMAGITIRDDPLGQKPECFDAFICYCPSDIEFVHEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIEKRCRRMVVVVSDEYLQSKECDFQTKFALSLSPGAHQKRLIPIKYKPMKKEFPSILRFITVCDYTNPCTQNWFWTRLAKALSMP

Target ORF information:

RefSeq Version	NM_001014382.2
Organism	Bos taurus(cattle)
Definition	Bos taurus MYD88 innate immune signal transduction adaptor (MYD88), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001014382.2

ORF Insert Sequence:

ATGGCTGAAG GAGTACCCCG CGCGGGGTCC GCGCTCCCCG CGGCTTCCTT GTCCTCCCTG 
CCCCTGGCAG CGCTCAACGT ACGAGTGCGG CGCCGCCTGT CGCTCTTCCT AAACGTGCGG 
GCGCCGGTGG CGGCCGACTG GACCGTGCTG GCGGAGGCGA TGGACTTCGA GTACTTGGAG 
ATCCAGCAGC TGGAGAAGTA CGCCGACCCC ACGAGCAGGC TCCTGGACGA CTGGCAGCGA 
CGTCCGGGAG CCTCAGTGGG CCGCCTGCTC GAGCTGCTCG CCAAGCTCGG CCGCGACGAC 
GTGCTGATGG AACTGGGACC CAGCATCGAG GAGGACTGCC AAAAGTATAT TCTGAAGCAG 
CAGCAGGAGG CATCTGAGAA GCCTTTACAG GTGGACTCTA TAGACAGCAG CATAACTCGG 
ATAAATGACA TGGCAGGCAT CACCATTCGC GACGACCCCC TAGGGCAAAA GCCCGAGTGT 
TTTGATGCCT TCATCTGCTA CTGCCCCAGC GATATTGAGT TTGTCCACGA GATGATCCGG 
CAGCTGGAAC AGACAAACTA TCGGCTGAAG TTGTGCGTGT CTGACCGTGA CGTCCTGCCT 
GGCACCTGTG TCTGGTCCAT CGCCAGTGAA CTCATTGAGA AGAGGTGCCG TCGGATGGTG 
GTGGTGGTCT CTGACGAATA CCTGCAAAGC AAGGAATGTG ATTTCCAGAC TAAGTTTGCA 
CTCAGCCTCT CTCCAGGTGC CCATCAGAAG CGACTGATCC CCATCAAGTA CAAGCCAATG 
AAGAAAGAGT TCCCCAGCAT CCTGCGCTTC ATCACTGTCT GTGACTACAC CAACCCCTGC 
ACCCAGAACT GGTTCTGGAC TCGCCTCGCC AAGGCCCTGT CCATGCCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MYD88 ( XM_005222379.3 ) cDNA ORF clone, Bos taurus(cattle) -> XP_005222436.1 Bos taurus myeloid differentiation primary response 88 (MYD88), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OBa31235
Clone ID Related Accession (Same CDS sequence)	XM_005222379.3
Accession Version	XM_005222379.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 840bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1525536000000
Organism	Bos taurus(cattle)
Product	myeloid differentiation primary response protein MyD88 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037349.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_005222379.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTGGAG CTCAGAACAC CTCAAAAGGC GGATTCCGGA TCCCCACATC CCCAGCACCC 
CCGCCCCGAG ATCTCGAAGG CAGTGATGGG GGGCCCCCCG CCTCCGCACA TCTACTGGGG 
CTCCAGATTG TAGGGCAGGG CGGTGCTTCT CGGAAAGAGA GACCGGCGGG GCGGGACCAG 
GTGGGCGGGG CGGCCGAAGG GGAAGGAGGA AGCACAGGCC CAGGACGCGA CTCGACTGCG 
CGGCGGCTCC CGCGGCAGCC CGCCATGGCT GAAGGAGTAC CCCGCGCGGG GTCCGCGCTC 
CCCGCGGCTT CCTTGTCCTC CCTGCCCCTG GCAGCGCTCA ACGTACGAGT GCGGCGCCGC 
CTGTCGCTCT TCCTAAACGT GCGGGCGCCG GTGGCGGCCG ACTGGACCGT GCTGGCGGAG 
GCGATGGACT TCGAGTACTT GGAGATCCAG CAGCTGGAGA AGTACGCCGA CCCCACGAGC 
AGGCTCCTGG ACGACTGGCA GCGACGTCCG GGAGCCTCAG TGGGCCGCCT GCTCGAGCTG 
CTCGCCAAGC TCGGCCGCGA CGACGTGCTG ATGGAACTGG GACCCAGCAT CGAGGAGGAC 
TGCCAAAAGT ATATTCTGAA GCAGCAGCAG GAGGCATCTG AGAAGCCTTT ACAGGTGGAC 
TCTATAGACA GCAGCATAAC TCGGATAAAT GACATGGCAG GCATCACCAT TCGCGACGAC 
CCCCTAGGTG CCGTCGGATG GTGGTGGTGG TCTCTGACGA ATACCTGCAA AGCAAGGAAT 
GTGATTTCCA GACTAAGTTT GCACTCAGCC TCTCTCCAGG TGCCCATCAG AAGCGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005222436.1
CDS	16..855
Translation	MGGAQNTSKGGFRIPTSPAPPPRDLEGSDGGPPASAHLLGLQIVGQGGASRKERPAGRDQVGGAAEGEGGSTGPGRDSTARRLPRQPAMAEGVPRAGSALPAASLSSLPLAALNVRVRRRLSLFLNVRAPVAADWTVLAEAMDFEYLEIQQLEKYADPTSRLLDDWQRRPGASVGRLLELLAKLGRDDVLMELGPSIEEDCQKYILKQQQEASEKPLQVDSIDSSITRINDMAGITIRDDPLGAVGWWWWSLTNTCKARNVISRLSLHSASLQVPIRSD

Target ORF information:

RefSeq Version	XM_005222379.3
Organism	Bos taurus(cattle)
Definition	Bos taurus myeloid differentiation primary response 88 (MYD88), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005222379.3

ORF Insert Sequence:

ATGGGTGGAG CTCAGAACAC CTCAAAAGGC GGATTCCGGA TCCCCACATC CCCAGCACCC 
CCGCCCCGAG ATCTCGAAGG CAGTGATGGG GGGCCCCCCG CCTCCGCACA TCTACTGGGG 
CTCCAGATTG TAGGGCAGGG CGGTGCTTCT CGGAAAGAGA GACCGGCGGG GCGGGACCAG 
GTGGGCGGGG CGGCCGAAGG GGAAGGAGGA AGCACAGGCC CAGGACGCGA CTCGACTGCG 
CGGCGGCTCC CGCGGCAGCC CGCCATGGCT GAAGGAGTAC CCCGCGCGGG GTCCGCGCTC 
CCCGCGGCTT CCTTGTCCTC CCTGCCCCTG GCAGCGCTCA ACGTACGAGT GCGGCGCCGC 
CTGTCGCTCT TCCTAAACGT GCGGGCGCCG GTGGCGGCCG ACTGGACCGT GCTGGCGGAG 
GCGATGGACT TCGAGTACTT GGAGATCCAG CAGCTGGAGA AGTACGCCGA CCCCACGAGC 
AGGCTCCTGG ACGACTGGCA GCGACGTCCG GGAGCCTCAG TGGGCCGCCT GCTCGAGCTG 
CTCGCCAAGC TCGGCCGCGA CGACGTGCTG ATGGAACTGG GACCCAGCAT CGAGGAGGAC 
TGCCAAAAGT ATATTCTGAA GCAGCAGCAG GAGGCATCTG AGAAGCCTTT ACAGGTGGAC 
TCTATAGACA GCAGCATAAC TCGGATAAAT GACATGGCAG GCATCACCAT TCGCGACGAC 
CCCCTAGGTG CCGTCGGATG GTGGTGGTGG TCTCTGACGA ATACCTGCAA AGCAAGGAAT 
GTGATTTCCA GACTAAGTTT GCACTCAGCC TCTCTCCAGG TGCCCATCAG AAGCGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Lactobacillus rhamnosus GR-1 Limits Escherichia coli-Induced Inflammatory Responses via Attenuating MyD88-Dependent and MyD88-Independent Pathway Activation in Bovine Endometrial Epithelial Cells.
Inflammation39(4)1483-94(2016 Aug)
Liu M,Wu Q,Wang M,Fu Y,Wang J

Mycoplasma bovis-derived lipid-associated membrane proteins activate IL-1β production through the NF-κB pathway via toll-like receptor 2 and MyD88.
Developmental and comparative immunology55111-8(2016 Feb)
Wang Y,Liu S,Li Y,Wang Q,Shao J,Chen Y,Xin J

Bovine viral diarrhea virus type 2 in vivo infection modulates TLR4 responsiveness in differentiated myeloid cells which is associated with decreased MyD88 expression.
Virus research20844-55(2015 Oct)
Schaut RG,McGill JL,Neill JD,Ridpath JF,Sacco RE

Heterozygosity at the A625C polymorphic site of the MyD88 gene is associated with Mycobacterium bovis infection in cattle.
Infection and immunity81(6)2139-44(2013 Jun)
Capparelli R,De Chiara F,Nocerino N,Medaglia C,Di Costanzo R,Ramunno L,Capuano F,Casalinuovo F,Di Matteo A,Iannelli D

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Marçais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

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MYD88 cDNA ORF clone, Bos taurus(cattle)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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