TRPC5 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	TRPC5
Entrez Gene ID	407103
Full Name	transient receptor potential cation channel subfamily C member 5
Synonyms	trp
General protein information	Preferred Names transient receptor potential cation channel subfamily C member 5 Names short transient receptor potential channel 5 transient receptor potential channel 5
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001166574.1	NP_001160046.1	short transient receptor potential channel 5

Pathways from BioSystems

Homologies

Bos taurus (cattle)	TRPC5	NP_001160046.1
Gallus gallus (chicken)	TRPC5	XP_420310.2
Canis lupus familiaris (dog)	TRPC5	XP_853241.1
Rattus norvegicus (Norway rat)	Trpc5	NP_543174.1
Homo sapiens (human)	TRPC5	NP_036603.1
Pan troglodytes (chimpanzee)	TRPC5	XP_003317691.1
Macaca mulatta (Rhesus monkey)	TRPC5	XP_001101078.1
Danio rerio (zebrafish)	LOC555897	XP_683649.2
Mus musculus (house mouse)	Trpc5	NP_033454.1
Xenopus tropicalis (tropical clawed frog)	trpc5	XP_002938829.1

Gene Ontology
Bibliography

Related articles in PubMed

Nitric oxide lacks direct effect on TRPC5 channels but suppresses endogenous TRPC5-containing channels in endothelial cells.
Wong CO, Sukumar P, Beech DJ, Yao X
Pflugers Archiv : European journal of physiology460(1)121-30(2010 Jun)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Marçais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Elucidation of a TRPC6-TRPC5 channel cascade that restricts endothelial cell movement.
Chaudhuri P, Colles SM, Bhat M, Van Wagoner DR, Birnbaumer L, Graham LM
Molecular biology of the cell19(8)3203-11(2008 Aug)

Nitric oxide activates TRP channels by cysteine S-nitrosylation.
Yoshida T, Inoue R, Morii T, Takahashi N, Yamamoto S, Hara Y, Tominaga M, Shimizu S, Sato Y, Mori Y
Nature chemical biology2(11)596-607(2006 Nov)

TRP4 (CCE1) protein is part of native calcium release-activated Ca2+-like channels in adrenal cells.
Philipp S, Trost C, Warnat J, Rautmann J, Himmerkus N, Schroth G, Kretz O, Nastainczyk W, Cavalie A, Hoth M, Flockerzi V
The Journal of biological chemistry275(31)23965-72(2000 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TRPC5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TRPC5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa35398	NM_001166574.1 Latest version!	Bos taurus transient receptor potential cation channel subfamily C member 5 (TRPC5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TRPC5 ( NM_001166574.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001160046.1 Bos taurus transient receptor potential cation channel subfamily C member 5 (TRPC5), mRNA.

Price & Availability↑

CloneID	OBa35398
Clone ID Related Accession (Same CDS sequence)	NM_001166574.1
Accession Version	NM_001166574.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2925bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573833600000
Organism	Bos taurus(cattle)
Product	short transient receptor potential channel 5
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from NKLS02000030.1. On Oct 28, 2009 this sequence version replaced XM_617015.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN03145413, SAMN03145419 [ECO:0000350] ##Evidence-Data-END##

ATGGCCCAAC TGTACTACAA AAAGGTCAAC TACTCACCAT ACAGAGACCG CATTCCCCTG 
CAGATTGTGA GGGCAGAGAC AGAGCTCTCT GCTGAGGAGA AGGCCTTCCT CAATGCTGTG 
GAGAAGGGGG ACTATGCCAC TGTGAAGCAG GCCCTCCAGG AGGCCGAGAT CTACTACAAT 
GTCAACATCA ACTGCATGGA CCCACTGGGC CGGAGCGCCC TGCTAATTGC CATTGAGAAT 
GAGAACTTGG AGATCATGGA GCTCCTGCTG AACCACAGTG TGTATGTTGG CGATGCACTG 
CTCTATGCCA TCCGCAAGGA AGTGGTGGGT GCTGTGGAGC TTCTGCTCAG CTACAGGCGG 
CCCAGTGGAG AGAAGCAGGT CCCCACTCTT ATGATGGACA CTCAGTTCTC TGAGTTCACA 
CCGGACATTA CTCCCATCAT GCTGGCTGCC CACACCAACA ACTACGAGAT CATCAAACTG 
CTCGTCCAAA AACGGGTCAC TATTCCCCGG CCCCACCAGA TCCGCTGCAA CTGTGTGGAG 
TGTGTGTCCA GTTCAGAGGT AGACAGCCTG CGCCACTCCC GCTCCCGACT GAACATCTAT 
AAAGCCCTGG CAAGTCCCTC ACTCATCGCC TTATCAAGTG AGGATCCCAT CCTAACTGCC 
TTCCGCCTGG GCTGGGAGCT CAAGGAGCTT AGCAAGGTGG AGAATGAGTT CAAGGCTGAG 
TACGAGGAGC TCTCCCAGCA GTGCAAGCTC TTTGCCAAAG ACCTGCTGGA CCAGGCTCGG 
AGCTCCCGGG AACTGGAGAT CATCCTCAAC CATCGAGATG ACCACAGTGA AGAGCTTGAC 
CCTCAAAAGT ACCATGATCT AGCCAAGCTG AAGGTGGCCA TCAAATATCA CCAGAAAGAG 
TTTGTGGCCC AGCCCAATTG CCAACAGTTG CTTGCCACTC TGTGGTACGA CGGCTTCCCT 
GGATGGCGGC GGAAACACTG GGTCGTCAAG CTTCTGACGT GCATGACCAT TGGGTTCCTG 
TTTCCCATGC TGTCTATTGC TTATCTCATC TCACCCAGGA GCAACCTTGG GCTGTTCATC 
AAGAAACCCT TCATCAAGTT TATCTGCCAC ACAGCGTCAT ATCTGACCTT CCTCTTCATG 
CTTCTCCTGG CTTCTCAGCA CATCGTCAGG ACAGACCTCC ATGTACAAGG ACCTCCCCCG 
ACTGTTGTGG AGTGGATGAT ACTGCCTTGG GTTCTCGGTT TCATTTGGGG GGAGATAAAG 
GAAATGTGGG ATGGTGGATT TACTGAATAC ATCCATGACT GGTGGAACCT GATGGATTTT 
GCAATGAACT CACTCTACCT GGCAACTATT TCCTTGAAGA TTGTAGCCTA TGTCAAGTAT 
AATGGTTCCC GTCCAAGGGA AGAATGGGAA ATGTGGCACC CGACTCTGAT TGCAGAAGCT 
CTCTTTGCGA TATCCAACAT TTTAAGTTCG TTGCGTCTCA TATCCCTGTT CACAGCCAAC 
TCCCACTTAG GGCCTCTGCA GATCTCTTTG GGGCGCATGT TGCTCGATAT CCTCAAATTC 
CTCTTTATCT ACTGCCTGGT ACTGCTGGCT TTTGCCAATG GATTGAACCA GCTTTACTTT 
TATTATGAGA CCAGAGCAAT CGATGAGCCC AACAACTGCA AGGGGATCAG ATGCGAGAAA 
CAGAACAATG CCTTCTCCAC GCTCTTTGAA ACCCTTCAGT CCCTCTTCTG GTCTGTATTC 
GGCCTTTTAA ATCTCTATGT CACCAATGTG AAAGCCAGAC ATGAGTTCAC AGAGTTTGTG 
GGAGCGACCA TGTTTGGGAC ATACAATGTC ATCTCCCTGG TAGTGCTGCT GAACATGCTG 
ATCGCCATGA TGAACAACTC CTACCAACTT ATTGCTGATC ATGCTGATAT TGAGTGGAAG 
TTTGCAAGGA CGAAGCTCTG GATGAGTTAC TTTGATGAAG GTGGCACCTT GCCACCTCCT 
TTCAACATTA TCCCCAGCCC CAAGTCATTT CTATACCTTG GCAACTGGTT CAACAACACC 
TTCTGCCCTA AAAGAGACCC TGATGGTAGA CGAAGAAGGC ACAACTTGAG AAGCTTCACA 
GAACGCCATG CTGACAGCCT GATACAGAAC CAACATTACC AGGAAGTTAT CAGGAATTTA 
GTCAAAAGAT ATGTGGCAGC TATGATAAGA AATTCCAAAA CAAATGAGGG ACTAACAGAA 
GAAAATTTTA AGGAATTAAA GCAGGATATC TCCAGCTTTC GATATGAAGT GCTTGACCTC 
TTGGGAAACA GGAAGCACCA AAGGAGAAGC TTTTCCACTA GCAGCACTGA ACTCTCTCAG 
AGGGATGATA CCAATGATGG CAGTGGTGGG GCTCGGGCCA AATCCAAGAG TGTCTCTTTC 
AATGTAGGCT GCAAGAAAAA AGCCTGCCAT GGGCCACCTC TCATCAGGAC TATGCCAAGA 
GTCGGTGGTG CCCAAGGCAA GTCAAAAGCT GAGTCATCAA GCAAACGATC CTTCATGGGT 
CCCTCTCTCA AGAAACTGGG TCTCCTATTC TCCAAGTTTA ATGGTCATAT GTCCGAACCC 
AGTTCAGAGC CGATGTACAC AATCTCTGAT GGAATTGTTC AGCCACACTA TATGTGGCAG 
GACATCAGAT ATTCTCAGAT GGAGAAAGGG AAAGCAGAGG CCTGTTCTCA AAGTGAAATT 
AACCTCAGTG AGGTAGAATT AGGTGAAGCC CGGGGCACTG CTCAGAGCAC TGAATGCCCT 
CTAGCCTGTT CCAGCTCTCT TCACTGTGTA TCCAGCATCT GTTCCTCAAA TTCTAAACTT 
TTAGACTCCT CAGAGGATGT ATTTGAAACG TGGGGAGAGG CTTGTGACCT GCTCATGCAC 
AAATGGGGTG ATGGACAGGA AGAACAAGTT ACAACTCGGC TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001160046.1
CDS	1..2925
Translation	MAQLYYKKVNYSPYRDRIPLQIVRAETELSAEEKAFLNAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIMELLLNHSVYVGDALLYAIRKEVVGAVELLLSYRRPSGEKQVPTLMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFAKDLLDQARSSRELEIILNHRDDHSEELDPQKYHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTASYLTFLFMLLLASQHIVRTDLHVQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNGSRPREEWEMWHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETRAIDEPNNCKGIRCEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFNNTFCPKRDPDGRRRRHNLRSFTERHADSLIQNQHYQEVIRNLVKRYVAAMIRNSKTNEGLTEENFKELKQDISSFRYEVLDLLGNRKHQRRSFSTSSTELSQRDDTNDGSGGARAKSKSVSFNVGCKKKACHGPPLIRTMPRVGGAQGKSKAESSSKRSFMGPSLKKLGLLFSKFNGHMSEPSSEPMYTISDGIVQPHYMWQDIRYSQMEKGKAEACSQSEINLSEVELGEARGTAQSTECPLACSSSLHCVSSICSSNSKLLDSSEDVFETWGEACDLLMHKWGDGQEEQVTTRL

Target ORF information:

RefSeq Version	NM_001166574.1
Organism	Bos taurus(cattle)
Definition	Bos taurus transient receptor potential cation channel subfamily C member 5 (TRPC5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166574.1

ORF Insert Sequence:

ATGGCCCAAC TGTACTACAA AAAGGTCAAC TACTCACCAT ACAGAGACCG CATTCCCCTG 
CAGATTGTGA GGGCAGAGAC AGAGCTCTCT GCTGAGGAGA AGGCCTTCCT CAATGCTGTG 
GAGAAGGGGG ACTATGCCAC TGTGAAGCAG GCCCTCCAGG AGGCCGAGAT CTACTACAAT 
GTCAACATCA ACTGCATGGA CCCACTGGGC CGGAGCGCCC TGCTAATTGC CATTGAGAAT 
GAGAACTTGG AGATCATGGA GCTCCTGCTG AACCACAGTG TGTATGTTGG CGATGCACTG 
CTCTATGCCA TCCGCAAGGA AGTGGTGGGT GCTGTGGAGC TTCTGCTCAG CTACAGGCGG 
CCCAGTGGAG AGAAGCAGGT CCCCACTCTT ATGATGGACA CTCAGTTCTC TGAGTTCACA 
CCGGACATTA CTCCCATCAT GCTGGCTGCC CACACCAACA ACTACGAGAT CATCAAACTG 
CTCGTCCAAA AACGGGTCAC TATTCCCCGG CCCCACCAGA TCCGCTGCAA CTGTGTGGAG 
TGTGTGTCCA GTTCAGAGGT AGACAGCCTG CGCCACTCCC GCTCCCGACT GAACATCTAT 
AAAGCCCTGG CAAGTCCCTC ACTCATCGCC TTATCAAGTG AGGATCCCAT CCTAACTGCC 
TTCCGCCTGG GCTGGGAGCT CAAGGAGCTT AGCAAGGTGG AGAATGAGTT CAAGGCTGAG 
TACGAGGAGC TCTCCCAGCA GTGCAAGCTC TTTGCCAAAG ACCTGCTGGA CCAGGCTCGG 
AGCTCCCGGG AACTGGAGAT CATCCTCAAC CATCGAGATG ACCACAGTGA AGAGCTTGAC 
CCTCAAAAGT ACCATGATCT AGCCAAGCTG AAGGTGGCCA TCAAATATCA CCAGAAAGAG 
TTTGTGGCCC AGCCCAATTG CCAACAGTTG CTTGCCACTC TGTGGTACGA CGGCTTCCCT 
GGATGGCGGC GGAAACACTG GGTCGTCAAG CTTCTGACGT GCATGACCAT TGGGTTCCTG 
TTTCCCATGC TGTCTATTGC TTATCTCATC TCACCCAGGA GCAACCTTGG GCTGTTCATC 
AAGAAACCCT TCATCAAGTT TATCTGCCAC ACAGCGTCAT ATCTGACCTT CCTCTTCATG 
CTTCTCCTGG CTTCTCAGCA CATCGTCAGG ACAGACCTCC ATGTACAAGG ACCTCCCCCG 
ACTGTTGTGG AGTGGATGAT ACTGCCTTGG GTTCTCGGTT TCATTTGGGG GGAGATAAAG 
GAAATGTGGG ATGGTGGATT TACTGAATAC ATCCATGACT GGTGGAACCT GATGGATTTT 
GCAATGAACT CACTCTACCT GGCAACTATT TCCTTGAAGA TTGTAGCCTA TGTCAAGTAT 
AATGGTTCCC GTCCAAGGGA AGAATGGGAA ATGTGGCACC CGACTCTGAT TGCAGAAGCT 
CTCTTTGCGA TATCCAACAT TTTAAGTTCG TTGCGTCTCA TATCCCTGTT CACAGCCAAC 
TCCCACTTAG GGCCTCTGCA GATCTCTTTG GGGCGCATGT TGCTCGATAT CCTCAAATTC 
CTCTTTATCT ACTGCCTGGT ACTGCTGGCT TTTGCCAATG GATTGAACCA GCTTTACTTT 
TATTATGAGA CCAGAGCAAT CGATGAGCCC AACAACTGCA AGGGGATCAG ATGCGAGAAA 
CAGAACAATG CCTTCTCCAC GCTCTTTGAA ACCCTTCAGT CCCTCTTCTG GTCTGTATTC 
GGCCTTTTAA ATCTCTATGT CACCAATGTG AAAGCCAGAC ATGAGTTCAC AGAGTTTGTG 
GGAGCGACCA TGTTTGGGAC ATACAATGTC ATCTCCCTGG TAGTGCTGCT GAACATGCTG 
ATCGCCATGA TGAACAACTC CTACCAACTT ATTGCTGATC ATGCTGATAT TGAGTGGAAG 
TTTGCAAGGA CGAAGCTCTG GATGAGTTAC TTTGATGAAG GTGGCACCTT GCCACCTCCT 
TTCAACATTA TCCCCAGCCC CAAGTCATTT CTATACCTTG GCAACTGGTT CAACAACACC 
TTCTGCCCTA AAAGAGACCC TGATGGTAGA CGAAGAAGGC ACAACTTGAG AAGCTTCACA 
GAACGCCATG CTGACAGCCT GATACAGAAC CAACATTACC AGGAAGTTAT CAGGAATTTA 
GTCAAAAGAT ATGTGGCAGC TATGATAAGA AATTCCAAAA CAAATGAGGG ACTAACAGAA 
GAAAATTTTA AGGAATTAAA GCAGGATATC TCCAGCTTTC GATATGAAGT GCTTGACCTC 
TTGGGAAACA GGAAGCACCA AAGGAGAAGC TTTTCCACTA GCAGCACTGA ACTCTCTCAG 
AGGGATGATA CCAATGATGG CAGTGGTGGG GCTCGGGCCA AATCCAAGAG TGTCTCTTTC 
AATGTAGGCT GCAAGAAAAA AGCCTGCCAT GGGCCACCTC TCATCAGGAC TATGCCAAGA 
GTCGGTGGTG CCCAAGGCAA GTCAAAAGCT GAGTCATCAA GCAAACGATC CTTCATGGGT 
CCCTCTCTCA AGAAACTGGG TCTCCTATTC TCCAAGTTTA ATGGTCATAT GTCCGAACCC 
AGTTCAGAGC CGATGTACAC AATCTCTGAT GGAATTGTTC AGCCACACTA TATGTGGCAG 
GACATCAGAT ATTCTCAGAT GGAGAAAGGG AAAGCAGAGG CCTGTTCTCA AAGTGAAATT 
AACCTCAGTG AGGTAGAATT AGGTGAAGCC CGGGGCACTG CTCAGAGCAC TGAATGCCCT 
CTAGCCTGTT CCAGCTCTCT TCACTGTGTA TCCAGCATCT GTTCCTCAAA TTCTAAACTT 
TTAGACTCCT CAGAGGATGT ATTTGAAACG TGGGGAGAGG CTTGTGACCT GCTCATGCAC 
AAATGGGGTG ATGGACAGGA AGAACAAGTT ACAACTCGGC TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Nitric oxide lacks direct effect on TRPC5 channels but suppresses endogenous TRPC5-containing channels in endothelial cells.
Pflugers Archiv : European journal of physiology460(1)121-30(2010 Jun)
Wong CO,Sukumar P,Beech DJ,Yao X

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Marçais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Elucidation of a TRPC6-TRPC5 channel cascade that restricts endothelial cell movement.
Molecular biology of the cell19(8)3203-11(2008 Aug)
Chaudhuri P,Colles SM,Bhat M,Van Wagoner DR,Birnbaumer L,Graham LM

Nitric oxide activates TRP channels by cysteine S-nitrosylation.
Nature chemical biology2(11)596-607(2006 Nov)
Yoshida T,Inoue R,Morii T,Takahashi N,Yamamoto S,Hara Y,Tominaga M,Shimizu S,Sato Y,Mori Y

TRP4 (CCE1) protein is part of native calcium release-activated Ca2+-like channels in adrenal cells.
The Journal of biological chemistry275(31)23965-72(2000 Aug)
Philipp S,Trost C,Warnat J,Rautmann J,Himmerkus N,Schroth G,Kretz O,Nastainczyk W,Cavalie A,Hoth M,Flockerzi V

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TRPC5 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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