| Gene Symbol | RABGEF1 |
| Entrez Gene ID | 282335 |
| Full Name | RAB guanine nucleotide exchange factor 1 |
| Synonyms | RABEX5 |
| Gene Type | protein-coding |
| Organism | Bos taurus(cattle) |
IVD Raw Materials
ORF » Species Summary » Bos taurus » RABGEF1 cDNA ORF clone
| Gene Symbol | RABGEF1 |
| Entrez Gene ID | 282335 |
| Full Name | RAB guanine nucleotide exchange factor 1 |
| Synonyms | RABEX5 |
| Gene Type | protein-coding |
| Organism | Bos taurus(cattle) |
| mRNA | Protein | Name |
|---|---|---|
| NM_174591.1 | NP_777016.1 | rab5 GDP/GTP exchange factor |
| Macaca mulatta (Rhesus monkey) | LOC695887 | XP_002803299.1 |
| Mus musculus (house mouse) | Rabgef1 | NP_001185988.1 |
| Drosophila melanogaster (fruit fly) | Rabex-5 | NP_612093.1 |
| Pan troglodytes (chimpanzee) | RABGEF1 | XP_003318527.1 |
| Rattus norvegicus (Norway rat) | Rabgef1 | NP_001101803.1 |
| Homo sapiens (human) | RABGEF1 | NP_001273990.1 |
| Canis lupus familiaris (dog) | RABGEF1 | XP_005620983.1 |
| Bos taurus (cattle) | RABGEF1 | NP_777016.1 |
| Oryza sativa (rice) | Os03g0842700 | NP_001051858.1 |
| Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005551 | XP_315556.4 |
| Caenorhabditis elegans (roundworm) | rabx-5 | NP_499337.3 |
| Danio rerio (zebrafish) | rabgef1 | NP_957137.1 |
Differential polyubiquitin recognition by tandem ubiquitin binding domains of Rabex-5.
Shin D, Lee SY, Han S, Ren S, Kim S, Aikawa Y, Lee S
Biochemical and biophysical research communications423(4)757-62(2012 Jul)
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Marçais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
Ubiquitin binding and conjugation regulate the recruitment of Rabex-5 to early endosomes.
Mattera R, Bonifacino JS
The EMBO journal27(19)2484-94(2008 Oct)
Rabaptin-5-independent membrane targeting and Rab5 activation by Rabex-5 in the cell.
Zhu H, Zhu G, Liu J, Liang Z, Zhang XC, Li G
Molecular biology of the cell18(10)4119-28(2007 Oct)
Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5.
Lee S, Tsai YC, Mattera R, Smith WJ, Kostelansky MS, Weissman AM, Bonifacino JS, Hurley JH
Nature structural & molecular biology13(3)264-71(2006 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following RABGEF1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RABGEF1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OBa41848 | |
| Clone ID Related Accession (Same CDS sequence) | NM_174591.1 | |
| Accession Version | NM_174591.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 1573660800000 | |
| Organism | Bos taurus(cattle) | |
| Product | rab5 GDP/GTP exchange factor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ001119.1. ##Evidence-Data-START## Transcript exon combination :: AJ001119.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145414 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGAGCCTTA AGTCTGAACG CCGAGGAATT CATGTGGATC AGTCGGAGCT CCTATGCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_777016.1 |
| CDS | 1..1479 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_174591.1 |
1 | ATGAGCCTTA AGTCTGAACG CCGAGGAATT CATGTGGATC AGTCGGAGCT CCTATGCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Differential polyubiquitin recognition by tandem ubiquitin binding domains of Rabex-5. |
A whole-genome assembly of the domestic cow, Bos taurus. |
Ubiquitin binding and conjugation regulate the recruitment of Rabex-5 to early endosomes. |
Rabaptin-5-independent membrane targeting and Rab5 activation by Rabex-5 in the cell. |
Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5. |