IGFBP2 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	IGFBP2
Entrez Gene ID	282260
Full Name	insulin like growth factor binding protein 2
General protein information	Preferred Names insulin like growth factor binding protein 2 Names insulin-like growth factor-binding protein 2 IBP-2 IGF-binding protein 2 IGFBP-2 insulin-like growth factor binding protein 2, 36kDa
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_174555.1	NP_776980.1	insulin-like growth factor-binding protein 2 precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	IGFBP2	XP_005640799.1
Gallus gallus (chicken)	IGFBP2	NP_990690.1
Pan troglodytes (chimpanzee)	IGFBP2	XP_003950020.1
Mus musculus (house mouse)	Igfbp2	NP_032368.2
Danio rerio (zebrafish)	igfbp2a	NP_571533.1
Macaca mulatta (Rhesus monkey)	IGFBP2	XP_001087071.1
Bos taurus (cattle)	IGFBP2	NP_776980.1
Xenopus tropicalis (tropical clawed frog)	igfbp2	NP_001093707.1
Homo sapiens (human)	IGFBP2	NP_000588.2
Rattus norvegicus (Norway rat)	Igfbp2	NP_037254.2
Danio rerio (zebrafish)	igfbp2b	NP_001119936.1

Gene Ontology
Bibliography

Related articles in PubMed

Periconceptional undernutrition modifies endocrine profiles and hepatic gene expression in sheep.
de Brun V, Meikle A, Casal A, Sequeira M, Contreras-Solís I, Carriquiry M, Forcada F, Sosa C, Abecia JA
Journal of animal physiology and animal nutrition99(4)710-8(2015 Aug)

Associations between bovine IGFBP2 polymorphisms with fertility, milk production, and metabolic status in UK dairy cows.
Clempson AM, Pollott GE, Brickell JS, Wathes DC
Animal biotechnology23(2)101-13(2012 Apr)

Influence of insulin-like growth factor-binding proteins-2 and -3 in the pathogenesis of cystic ovarian disease in cattle.
Rodríguez FM, Salvetti NR, Panzani CG, Barbeito CG, Ortega HH, Rey F
Animal reproduction science128(1-4)1-10(2011 Oct)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Marçais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Insulin increases 17 beta-estradiol production by the dominant follicle of the first postpartum follicle wave in dairy cows.
Butler ST, Pelton SH, Butler WR
Reproduction (Cambridge, England)127(5)537-45(2004 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following IGFBP2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IGFBP2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa41332	NM_174555.1 Latest version!	Bos taurus insulin like growth factor binding protein 2 (IGFBP2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IGFBP2 ( NM_174555.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776980.1 Bos taurus insulin like growth factor binding protein 2 (IGFBP2), mRNA.

Price & Availability↑

CloneID	OBa41332
Clone ID Related Accession (Same CDS sequence)	NM_174555.1
Accession Version	NM_174555.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 954bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Bos taurus(cattle)
Product	insulin-like growth factor-binding protein 2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF074854.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF074854.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145412, SAMN03145413 [ECO:0000348] ##Evidence-Data-END##

ATGCAGCCGA GACTGGGCGG CCCCGCGCTG CTGCTGCTGC CGCCGCTGCT GCTGCTGCTG 
CTGCTGGGCG CGGGCGGCGG CGACTGCGGG GCGCGCGCCG AGGTGCTGTT CCGCTGCCCG 
CCCTGCACGC CCGAGAGCCT GGCCGCCTGC AAGCCCCCGC CCGGCGCCGC GGCCGGGCCG 
GCCGGCGACG CCCGCGTGCC CTGCGAGCTG GTCCGCGAGC CGGGCTGCGG CTGCTGCTCC 
GTGTGCGCCC GGCTGGAGGG AGAGCGGTGC GGCGTGTACA CCCCGCGCTG CGGTCAGGGG 
CTGCGCTGCT ATCCCAACCC GGGCTCCGAG CTGCCCCTGA GGGCGCTGGT CCACGGCGAG 
GGCACTTGCG AAAAGCACGG CGATGCTGAG TACAGCGCCA GCCCCGAGCA GGTTGCAGAC 
AACGGCGAGG AGCACTCTGA GGGAGGCCTG GTCGAGAACC ACGTGGACGG GAACGTGAAC 
TTGATGGGAG GTGGAGGTGG TGCCGGTCGG AAGCCCCTCA AGTCCGGCAT GAAGGAGCTG 
GCCGTGTTCC GGGAGAAGGT CACGGAGCAG CACCGGCAGA TGGGCAAGGG TGGCAAACAT 
CACCTCGGCC TGGAGGAGCC CAAGAAGCTG CGGCCGCCAC CTGCCAGGAC CCCCTGCCAG 
CAGGAATTGG ACCAGGTCCT GGAGCGGATC TCCACCATGC GCCTTCCGGA TGAGCGGGGT 
CCCCTGGAGC ACCTCTACTC CCTACACATC CCCAACTGTG ACAAGCATGG CCTGTACAAC 
CTCAAACAGT GCAAGATGTC TCTGAACGGG CAGCGTGGGG AGTGCTGGTG TGTGAACCCT 
AACACCGGGA AGCTGATCCA GGGAGCCCCC ACCATCCGGG GAGACCCCGA GTGTCATCTC 
TTCTACAACG AGCAGCAGGG GGCTCGAGGG GTGCACACCC AGCGGATGCA GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776980.1
CDS	1..954
Translation	MQPRLGGPALLLLPPLLLLLLLGAGGGDCGARAEVLFRCPPCTPESLAACKPPPGAAAGPAGDARVPCELVREPGCGCCSVCARLEGERCGVYTPRCGQGLRCYPNPGSELPLRALVHGEGTCEKHGDAEYSASPEQVADNGEEHSEGGLVENHVDGNVNLMGGGGGAGRKPLKSGMKELAVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPECHLFYNEQQGARGVHTQRMQ

Target ORF information:

RefSeq Version	NM_174555.1
Organism	Bos taurus(cattle)
Definition	Bos taurus insulin like growth factor binding protein 2 (IGFBP2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174555.1

ORF Insert Sequence:

ATGCAGCCGA GACTGGGCGG CCCCGCGCTG CTGCTGCTGC CGCCGCTGCT GCTGCTGCTG 
CTGCTGGGCG CGGGCGGCGG CGACTGCGGG GCGCGCGCCG AGGTGCTGTT CCGCTGCCCG 
CCCTGCACGC CCGAGAGCCT GGCCGCCTGC AAGCCCCCGC CCGGCGCCGC GGCCGGGCCG 
GCCGGCGACG CCCGCGTGCC CTGCGAGCTG GTCCGCGAGC CGGGCTGCGG CTGCTGCTCC 
GTGTGCGCCC GGCTGGAGGG AGAGCGGTGC GGCGTGTACA CCCCGCGCTG CGGTCAGGGG 
CTGCGCTGCT ATCCCAACCC GGGCTCCGAG CTGCCCCTGA GGGCGCTGGT CCACGGCGAG 
GGCACTTGCG AAAAGCACGG CGATGCTGAG TACAGCGCCA GCCCCGAGCA GGTTGCAGAC 
AACGGCGAGG AGCACTCTGA GGGAGGCCTG GTCGAGAACC ACGTGGACGG GAACGTGAAC 
TTGATGGGAG GTGGAGGTGG TGCCGGTCGG AAGCCCCTCA AGTCCGGCAT GAAGGAGCTG 
GCCGTGTTCC GGGAGAAGGT CACGGAGCAG CACCGGCAGA TGGGCAAGGG TGGCAAACAT 
CACCTCGGCC TGGAGGAGCC CAAGAAGCTG CGGCCGCCAC CTGCCAGGAC CCCCTGCCAG 
CAGGAATTGG ACCAGGTCCT GGAGCGGATC TCCACCATGC GCCTTCCGGA TGAGCGGGGT 
CCCCTGGAGC ACCTCTACTC CCTACACATC CCCAACTGTG ACAAGCATGG CCTGTACAAC 
CTCAAACAGT GCAAGATGTC TCTGAACGGG CAGCGTGGGG AGTGCTGGTG TGTGAACCCT 
AACACCGGGA AGCTGATCCA GGGAGCCCCC ACCATCCGGG GAGACCCCGA GTGTCATCTC 
TTCTACAACG AGCAGCAGGG GGCTCGAGGG GTGCACACCC AGCGGATGCA GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Periconceptional undernutrition modifies endocrine profiles and hepatic gene expression in sheep.
Journal of animal physiology and animal nutrition99(4)710-8(2015 Aug)
de Brun V,Meikle A,Casal A,Sequeira M,Contreras-Solís I,Carriquiry M,Forcada F,Sosa C,Abecia JA

Associations between bovine IGFBP2 polymorphisms with fertility, milk production, and metabolic status in UK dairy cows.
Animal biotechnology23(2)101-13(2012 Apr)
Clempson AM,Pollott GE,Brickell JS,Wathes DC

Influence of insulin-like growth factor-binding proteins-2 and -3 in the pathogenesis of cystic ovarian disease in cattle.
Animal reproduction science128(1-4)1-10(2011 Oct)
Rodríguez FM,Salvetti NR,Panzani CG,Barbeito CG,Ortega HH,Rey F

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Marçais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Insulin increases 17 beta-estradiol production by the dominant follicle of the first postpartum follicle wave in dairy cows.
Reproduction (Cambridge, England)127(5)537-45(2004 May)
Butler ST,Pelton SH,Butler WR

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IGFBP2 cDNA ORF clone, Bos taurus(cattle)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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