ITGA5 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	ITGA5
Entrez Gene ID	281873
Full Name	integrin subunit alpha 5
General protein information	Preferred Names integrin subunit alpha 5 Names integrin alpha-5 CD49 antigen-like family member E VLA-5 fibronectin receptor subunit alpha integrin alpha-F integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001166500.1	NP_001159972.1	integrin alpha-5
XM_024991353.1	XP_024847121.1	integrin alpha-5 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Itga5	NP_001101588.1
Pan troglodytes (chimpanzee)	ITGA5	XP_003313671.2
Homo sapiens (human)	ITGA5	NP_002196.2
Macaca mulatta (Rhesus monkey)	ITGA5	XP_001110116.2
Mus musculus (house mouse)	Itga5	NP_034707.3
Canis lupus familiaris (dog)	ITGA5	XP_005636796.1
Bos taurus (cattle)	ITGA5	NP_001159972.1
Xenopus tropicalis (tropical clawed frog)	itga5	XP_002935705.2
Danio rerio (zebrafish)	itga5	NP_001004288.2

Gene Ontology
Bibliography

Related articles in PubMed

X-linked inhibitor of apoptosis protein controls alpha5-integrin-mediated cell adhesion and migration.
Kim J, Ahn S, Ko YG, Boo YC, Chi SG, Ni CW, Go YM, Jo H, Park H
American journal of physiology. Heart and circulatory physiology299(2)H300-9(2010 Aug)

Expression and putative function of fibronectin and its receptor (integrin alpha(5)beta(1)) in male and female gametes during bovine fertilization in vitro.
Thys M, Nauwynck H, Maes D, Hoogewijs M, Vercauteren D, Rijsselaere T, Favoreel H, Van Soom A
Reproduction (Cambridge, England)138(3)471-82(2009 Sep)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Marçais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Matrix-specific suppression of integrin activation in shear stress signaling.
Orr AW, Ginsberg MH, Shattil SJ, Deckmyn H, Schwartz MA
Molecular biology of the cell17(11)4686-97(2006 Nov)

Regulation of Ca2+-dependent K+ current by alphavbeta3 integrin engagement in vascular endothelium.
Kawasaki J, Davis GE, Davis MJ
The Journal of biological chemistry279(13)12959-66(2004 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ITGA5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ITGA5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa44505	NM_001166500.1 Latest version!	Bos taurus integrin subunit alpha 5 (ITGA5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
OBa234178	XM_024991353.1 Latest version!	Bos taurus integrin subunit alpha 5 (ITGA5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ITGA5 ( NM_001166500.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001159972.1 Bos taurus integrin subunit alpha 5 (ITGA5), mRNA.

Price & Availability↑

CloneID	OBa44505
Clone ID Related Accession (Same CDS sequence)	NM_001166500.1
Accession Version	NM_001166500.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3168bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1576771200000
Organism	Bos taurus(cattle)
Product	integrin alpha-5
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from NKLS02000005.1. On Oct 28, 2009 this sequence version replaced XM_614854.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR5571257.52797.1, SRR5571259.34430.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145415 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: downstream AUG is associated with N-terminal localization signal ##RefSeq-Attributes-END##

ATGGGGAGCC GGACGCCAGG GTCCCCTCTC CACGCCGTGC AGCTGCGCCG GGGCGCCCGG 
CGCAGACCCC GGCTGCTGCC GTTGTTGCCG CCGCTGCTGC TGCTGCTGCT GCCGCCGCCG 
CCCCGGGTCG GGGGCTTCAA TTTAGACGCG GAGGCCCCGG CAGTGCTCTC CGGGCCCCCG 
GGCTCCTTCT TCGGCTTCTC GGTGGAGTTT TACCGGCCGG GGACGGACGG GGTCAGCGTG 
CTGGTGGGGG CGCCCAAGGC TAACACCAGC CAGCCGGGAG TGCTGCAGGG CGGTGCCGTC 
TACCTCTGCC CCTGGGGCAC CAGCCCGGCA CAGTGCACCC CCATTGAATT TGACAGCAAA 
GGCTCTCGGA TCTTCGAGTC CTCAACGTCC AGCTCAGAGG GAGAGGAGCC TGTGGAGTAC 
AAGTCCCTGC AGTGGTTTGG AGCAACAGTG CGAGCCCATG GCTCCTCCAT CCTGGCCTGT 
GCTCCCCTCT ACAGCTGGCG CACCGAGAAG GAGCCGCAGA GTGATCCTGT GGGCACCTGC 
TACCTCTCCA CAGGCAACTT CACCCAGATT CTGGAGTATG CACCCTGCCG CTCAGATTTC 
AGCCAAGAAG CAGGACAGGG TTACTGCCAA GGGGGCTTCA GTGCTGAGTT CACCAAGACG 
GGGCGTGTGG TCCTGGGTGG ACCAGGGAGC TATTTCTGGC AAGGCCAGAT CCTGTCCGCC 
ACCCAGGAGC AGATTGCAGA ATCCTATTAT CCCGGGTACC TGATCAACCC AGTTCGGGGG 
CAGCTGCAGA CTCGCCAGGC CAGTTCCATC TACGATGACA GCTACCTGGG ATACTCTGTG 
GCTGTGGGTG AATTCAGTGG TGATGATAGA GAAGACTTCG TTGCTGGTGT GCCCAAAGGG 
AACCTCACCT ATGGCTATGT CACCATCCTT AATGGCTCAG ACATCCGGTC CCTCTACAAC 
TTTTCAGGGG AACAGATGGC CTCCTACTTT GGCTACGCAG TGGCCGCCAC AGACATCAAC 
GGGGATGGGC TGGACGACTT GCTGGTAGGG GCGCCCCTGC TCATGGAGCG GACAGCCGAC 
GGGCGGCCGC AGGAGGTGGG CAGGGTCTAT ATCTACCTGC AGCGCCTGGC TGGCATGGAG 
CCCACGCCCA CCCTGACCCT CACTGGCCAG GATGAGTTTG GCCGGTTCGG CAGCTCCCTG 
ACCCCCCTGG GGGACCTAGA CCAGGATGGC TACAATGATG TAGCCATTGG GGCTGCCTTT 
GGTGGGGAGA ACCGGCAGGG AGTGGTGTTT ATATTCCCTG GGGGCCCAGG GGGTCTGGCG 
TCTAAGCCTT CCCAGGTTCT GCTGCCCCTG TGGGCAGCTG GCCACACACC GGACTTCTTT 
GGCTCTGCCC TTCGAGGAGG CCGAGACCTA GATGGCAATG GATACCCTGA TCTGATTGTG 
GGGTCCTTTG GTGTAGACAA GGCTGTGGTA TACAGGGGTC GCCCCATCGT GTCTGCCAGT 
GCCTCCCTCA CCATCTTTCC TGCCATGTTC AACCCAGAGG AGCACAGCTG CAGCTTGGAG 
GGAAACCCTG TGACTTGCAT CAACCTTAGC TTCTGCCTCA ATGCTTCCGG AAAACATGTT 
CCTGACTCCA TCGGCTTCAC GGTGGAGCTC CAGTTGGACT GGCAGAAGCA GAAGGGCGGG 
GTGCGGCGGG CGCTGTTCCT GGCCTCCCGA CAGGCCACCC TGACCCAGAC CCTGCTCATC 
CAGAACGGGG CTCGGGAGGA CTGCAGAGAG ATGAAGATCT ACCTCAGGAA CGAGTCAGAG 
TTTCGAGATA AACTCTCCCC GATTCACATC GCCCTCAATT TCTCCCTGGA CCCTCAAGCC 
CCAGTGGACA GCCACGGCCT CCGGCCAGTC CTACACTACC AGAGCAAGAG CCGCATAGAG 
GACAAGGCTC AGATCTTGCT GGACTGTGGA GAAGACAATA TCTGTGTGCC AGACCTACAG 
CTGGAAGTGT TTGGGGAGCA GAACCACGTA TACCTGGGCG ACAAGAATTC TCTGAACCTC 
ACCTTCCACG CCCAGAATGT GGGTGAGGGT GGCGCCTACG AGGCAGAGCT TCGGGTCACA 
GCCCCTCCGG AGGCTGAGTA CTCGGGACTC GTCAGACACC CAGGGAACTT CTCCAGCCTG 
AGCTGCGACT ACTTTGCTGT GAACCAGAGT CGTCTGCTGG TGTGTGACCT GGGCAACCCC 
ATGAAGGCTG GGGCCAGTCT CTGGGGTGGC CTTCGGTTCA CAGTCCCTCA CCTCAGGGAC 
ACGAAGAAAA CCATTCAGTT TGACTTCCAG ATCCTCAGCA AGAATCTCAA CAACTCGCAA 
AGCGACGTGG TTTCCTTCCG GCTCTCGGTG GAGGCTCAGG CCCAGGTCTC TCTTAACGGT 
GTCTCCAAGC CCGAGGCAGT GCTATTTCCG ATGAGCGACT GGCATCCCCA AGACCAGCCG 
CAGGAGGAGG GTGACGTGGG CCCTGCTGTC CACCATGTCT ATGAGCTCAT CAACCTGGGC 
CCCAGCTCTA TTAGCCAGGG CGTGTTGGAG CTCAGCTGTC CCCATGCTCT GGATGGCCAG 
CAGCTCCTCT ACGTGACCAG GGTCACAGGA CTCAGCAACT GCACCACCAG TCACCCCCCC 
AACCCAGAGG GCCTGGAGTT GGATCCTGAG GGTTCCCAGC ACCACCGGCT GCAAAGACGG 
GATGTTCCAG GTCGGAGCCC TGCCTCCTCA GGGCCTCAGA TTCTGAAATG CCCAGAGGCA 
GAGTGTTTCA AGCTGCGCTG TGAGCTGGGG CCACTGCACC GGCAAGAGAG CCGAAGTCTG 
CAACTGCATT TCCGTGTCTG GGCCAAGACC TTCCTACAGC GGGAGCACCA GCCATTTAGC 
CTGCAGTGTG AGGCCGTGTA TGAAGCCCTG AAGATGCCCT ATAAAATCCT GCCTCGGCAG 
CTTCCCCAGA AGGCGCTGCA GGTGGCCACA GCTGTGCAGT GGATCAAGGC AGAAGGCAGC 
CACGGAGTCC CTCTCTGGAT CATTATCTTA GCCATCCTCA TTGGCCTCCT GCTCCTCGGT 
CTGCTCATCT ATATCCTCTA CAAGCTCGGA TTCTTCAAAC GCTCCCTCCC GTACGGCACC 
GCCATGGAAA AAGCTCAGCT CAAGCCTCCA GCCACCTCCG ATGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159972.1
CDS	247..3414
Translation	MGSRTPGSPLHAVQLRRGARRRPRLLPLLPPLLLLLLPPPPRVGGFNLDAEAPAVLSGPPGSFFGFSVEFYRPGTDGVSVLVGAPKANTSQPGVLQGGAVYLCPWGTSPAQCTPIEFDSKGSRIFESSTSSSEGEEPVEYKSLQWFGATVRAHGSSILACAPLYSWRTEKEPQSDPVGTCYLSTGNFTQILEYAPCRSDFSQEAGQGYCQGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQIAESYYPGYLINPVRGQLQTRQASSIYDDSYLGYSVAVGEFSGDDREDFVAGVPKGNLTYGYVTILNGSDIRSLYNFSGEQMASYFGYAVAATDINGDGLDDLLVGAPLLMERTADGRPQEVGRVYIYLQRLAGMEPTPTLTLTGQDEFGRFGSSLTPLGDLDQDGYNDVAIGAAFGGENRQGVVFIFPGGPGGLASKPSQVLLPLWAAGHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGRPIVSASASLTIFPAMFNPEEHSCSLEGNPVTCINLSFCLNASGKHVPDSIGFTVELQLDWQKQKGGVRRALFLASRQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIHIALNFSLDPQAPVDSHGLRPVLHYQSKSRIEDKAQILLDCGEDNICVPDLQLEVFGEQNHVYLGDKNSLNLTFHAQNVGEGGAYEAELRVTAPPEAEYSGLVRHPGNFSSLSCDYFAVNQSRLLVCDLGNPMKAGASLWGGLRFTVPHLRDTKKTIQFDFQILSKNLNNSQSDVVSFRLSVEAQAQVSLNGVSKPEAVLFPMSDWHPQDQPQEEGDVGPAVHHVYELINLGPSSISQGVLELSCPHALDGQQLLYVTRVTGLSNCTTSHPPNPEGLELDPEGSQHHRLQRRDVPGRSPASSGPQILKCPEAECFKLRCELGPLHRQESRSLQLHFRVWAKTFLQREHQPFSLQCEAVYEALKMPYKILPRQLPQKALQVATAVQWIKAEGSHGVPLWIIILAILIGLLLLGLLIYILYKLGFFKRSLPYGTAMEKAQLKPPATSDA

Target ORF information:

RefSeq Version	NM_001166500.1
Organism	Bos taurus(cattle)
Definition	Bos taurus integrin subunit alpha 5 (ITGA5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166500.1

ORF Insert Sequence:

ATGGGGAGCC GGACGCCAGG GTCCCCTCTC CACGCCGTGC AGCTGCGCCG GGGCGCCCGG 
CGCAGACCCC GGCTGCTGCC GTTGTTGCCG CCGCTGCTGC TGCTGCTGCT GCCGCCGCCG 
CCCCGGGTCG GGGGCTTCAA TTTAGACGCG GAGGCCCCGG CAGTGCTCTC CGGGCCCCCG 
GGCTCCTTCT TCGGCTTCTC GGTGGAGTTT TACCGGCCGG GGACGGACGG GGTCAGCGTG 
CTGGTGGGGG CGCCCAAGGC TAACACCAGC CAGCCGGGAG TGCTGCAGGG CGGTGCCGTC 
TACCTCTGCC CCTGGGGCAC CAGCCCGGCA CAGTGCACCC CCATTGAATT TGACAGCAAA 
GGCTCTCGGA TCTTCGAGTC CTCAACGTCC AGCTCAGAGG GAGAGGAGCC TGTGGAGTAC 
AAGTCCCTGC AGTGGTTTGG AGCAACAGTG CGAGCCCATG GCTCCTCCAT CCTGGCCTGT 
GCTCCCCTCT ACAGCTGGCG CACCGAGAAG GAGCCGCAGA GTGATCCTGT GGGCACCTGC 
TACCTCTCCA CAGGCAACTT CACCCAGATT CTGGAGTATG CACCCTGCCG CTCAGATTTC 
AGCCAAGAAG CAGGACAGGG TTACTGCCAA GGGGGCTTCA GTGCTGAGTT CACCAAGACG 
GGGCGTGTGG TCCTGGGTGG ACCAGGGAGC TATTTCTGGC AAGGCCAGAT CCTGTCCGCC 
ACCCAGGAGC AGATTGCAGA ATCCTATTAT CCCGGGTACC TGATCAACCC AGTTCGGGGG 
CAGCTGCAGA CTCGCCAGGC CAGTTCCATC TACGATGACA GCTACCTGGG ATACTCTGTG 
GCTGTGGGTG AATTCAGTGG TGATGATAGA GAAGACTTCG TTGCTGGTGT GCCCAAAGGG 
AACCTCACCT ATGGCTATGT CACCATCCTT AATGGCTCAG ACATCCGGTC CCTCTACAAC 
TTTTCAGGGG AACAGATGGC CTCCTACTTT GGCTACGCAG TGGCCGCCAC AGACATCAAC 
GGGGATGGGC TGGACGACTT GCTGGTAGGG GCGCCCCTGC TCATGGAGCG GACAGCCGAC 
GGGCGGCCGC AGGAGGTGGG CAGGGTCTAT ATCTACCTGC AGCGCCTGGC TGGCATGGAG 
CCCACGCCCA CCCTGACCCT CACTGGCCAG GATGAGTTTG GCCGGTTCGG CAGCTCCCTG 
ACCCCCCTGG GGGACCTAGA CCAGGATGGC TACAATGATG TAGCCATTGG GGCTGCCTTT 
GGTGGGGAGA ACCGGCAGGG AGTGGTGTTT ATATTCCCTG GGGGCCCAGG GGGTCTGGCG 
TCTAAGCCTT CCCAGGTTCT GCTGCCCCTG TGGGCAGCTG GCCACACACC GGACTTCTTT 
GGCTCTGCCC TTCGAGGAGG CCGAGACCTA GATGGCAATG GATACCCTGA TCTGATTGTG 
GGGTCCTTTG GTGTAGACAA GGCTGTGGTA TACAGGGGTC GCCCCATCGT GTCTGCCAGT 
GCCTCCCTCA CCATCTTTCC TGCCATGTTC AACCCAGAGG AGCACAGCTG CAGCTTGGAG 
GGAAACCCTG TGACTTGCAT CAACCTTAGC TTCTGCCTCA ATGCTTCCGG AAAACATGTT 
CCTGACTCCA TCGGCTTCAC GGTGGAGCTC CAGTTGGACT GGCAGAAGCA GAAGGGCGGG 
GTGCGGCGGG CGCTGTTCCT GGCCTCCCGA CAGGCCACCC TGACCCAGAC CCTGCTCATC 
CAGAACGGGG CTCGGGAGGA CTGCAGAGAG ATGAAGATCT ACCTCAGGAA CGAGTCAGAG 
TTTCGAGATA AACTCTCCCC GATTCACATC GCCCTCAATT TCTCCCTGGA CCCTCAAGCC 
CCAGTGGACA GCCACGGCCT CCGGCCAGTC CTACACTACC AGAGCAAGAG CCGCATAGAG 
GACAAGGCTC AGATCTTGCT GGACTGTGGA GAAGACAATA TCTGTGTGCC AGACCTACAG 
CTGGAAGTGT TTGGGGAGCA GAACCACGTA TACCTGGGCG ACAAGAATTC TCTGAACCTC 
ACCTTCCACG CCCAGAATGT GGGTGAGGGT GGCGCCTACG AGGCAGAGCT TCGGGTCACA 
GCCCCTCCGG AGGCTGAGTA CTCGGGACTC GTCAGACACC CAGGGAACTT CTCCAGCCTG 
AGCTGCGACT ACTTTGCTGT GAACCAGAGT CGTCTGCTGG TGTGTGACCT GGGCAACCCC 
ATGAAGGCTG GGGCCAGTCT CTGGGGTGGC CTTCGGTTCA CAGTCCCTCA CCTCAGGGAC 
ACGAAGAAAA CCATTCAGTT TGACTTCCAG ATCCTCAGCA AGAATCTCAA CAACTCGCAA 
AGCGACGTGG TTTCCTTCCG GCTCTCGGTG GAGGCTCAGG CCCAGGTCTC TCTTAACGGT 
GTCTCCAAGC CCGAGGCAGT GCTATTTCCG ATGAGCGACT GGCATCCCCA AGACCAGCCG 
CAGGAGGAGG GTGACGTGGG CCCTGCTGTC CACCATGTCT ATGAGCTCAT CAACCTGGGC 
CCCAGCTCTA TTAGCCAGGG CGTGTTGGAG CTCAGCTGTC CCCATGCTCT GGATGGCCAG 
CAGCTCCTCT ACGTGACCAG GGTCACAGGA CTCAGCAACT GCACCACCAG TCACCCCCCC 
AACCCAGAGG GCCTGGAGTT GGATCCTGAG GGTTCCCAGC ACCACCGGCT GCAAAGACGG 
GATGTTCCAG GTCGGAGCCC TGCCTCCTCA GGGCCTCAGA TTCTGAAATG CCCAGAGGCA 
GAGTGTTTCA AGCTGCGCTG TGAGCTGGGG CCACTGCACC GGCAAGAGAG CCGAAGTCTG 
CAACTGCATT TCCGTGTCTG GGCCAAGACC TTCCTACAGC GGGAGCACCA GCCATTTAGC 
CTGCAGTGTG AGGCCGTGTA TGAAGCCCTG AAGATGCCCT ATAAAATCCT GCCTCGGCAG 
CTTCCCCAGA AGGCGCTGCA GGTGGCCACA GCTGTGCAGT GGATCAAGGC AGAAGGCAGC 
CACGGAGTCC CTCTCTGGAT CATTATCTTA GCCATCCTCA TTGGCCTCCT GCTCCTCGGT 
CTGCTCATCT ATATCCTCTA CAAGCTCGGA TTCTTCAAAC GCTCCCTCCC GTACGGCACC 
GCCATGGAAA AAGCTCAGCT CAAGCCTCCA GCCACCTCCG ATGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITGA5 ( XM_024991353.1 ) cDNA ORF clone, Bos taurus(cattle) -> XP_024847121.1 Bos taurus integrin subunit alpha 5 (ITGA5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa234178
Clone ID Related Accession (Same CDS sequence)	XM_024991353.1
Accession Version	XM_024991353.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3186bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1525536000000
Organism	Bos taurus(cattle)
Product	integrin alpha-5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037332.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGTATG GGAAAGGTGT TAAGAGGCTG AGACAAAGAT CCAGCCAGGA TGGGGAGGTC 
CCACCAGAGC CCAGGGTGAG GGCAGGCCCA GGCCCCGGGG AACAATCTGT TCTCACCATC 
CTCCAGGGCC TCTCTCCACT TCTACTGCCT GATTTCCAAG CCTCACATTT TCCTCCTACA 
CACCCCAGGG CTGGGCAGCC GGACGCCTGG GTCTTGCCCA GAGAAGGGCC TTGGCTTGGG 
AGCAGAGGGG TCAGCGTGCT GGTGGGGGCG CCCAAGGCTA ACACCAGCCA GCCGGGAGTG 
CTGCAGGGCG GTGCCGTCTA CCTCTGCCCC TGGGGCACCA GCCCGGCACA GTGCACCCCC 
ATTGAATTTG ACAGCAAAGG CTCTCGGATC TTCGAGTCCT CAACGTCCAG CTCAGAGGGA 
GAGGAGCCTG TGGAGTACAA GTCCCTGCAG TGGTTTGGAG CAACAGTGCG AGCCCATGGC 
TCCTCCATCC TGGCCTGTGC TCCCCTCTAC AGCTGGCGCA CCGAGAAGGA GCCGCAGAGT 
GATCCTGTGG GCACCTGCTA CCTCTCCACA GGCAACTTCA CCCAGATTCT GGAGTATGCA 
CCCTGCCGCT CAGATTTCAG CCAAGAAGCA GGACAGGGTT ACTGCCAAGG GGGCTTCAGT 
GCTGAGTTCA CCAAGACGGG GCGTGTGGTC CTGGGTGGAC CAGGGAGCTA TTTCTGGCAA 
GGCCAGATCC TGTCCGCCAC CCAGGAGCAG ATTGCAGAAT CCTATTATCC CGGGTACCTG 
ATCAACCCAG TTCGGGGGCA GCTGCAGACT CGCCAGGCCA GTTCCATCTA CGATGACAGC 
TACCTGGGAT ACTCTGTGGC TGTGGGTGAA TTCAGTGGTG ATGATAGAGA AGACTTCGTT 
GCTGGTGTGC CCAAAGGGAA CCTCACCTAT GGCTATGTCA CCATCCTTAA TGGCTCAGAC 
ATCCGGTCCC TCTACAACTT TTCAGGGGAA CAGATGGCCT CCTACTTTGG CTACGCAGTG 
GCCGCCACAG ACATCAACGG GGATGGGCTG GACGACTTGC TGGTAGGGGC GCCCCTGCTC 
ATGGAGCGGA CAGCCGACGG GCGGCCGCAG GAGGTGGGCA GGGTCTATAT CTACCTGCAG 
CGCCTGGCTG GCATGGAGCC CACGCCCACC CTGACCCTCA CTGGCCAGGA TGAGTTTGGC 
CGGTTCGGCA GCTCCCTGAC CCCCCTGGGG GACCTAGACC AGGATGGCTA CAATGATGTA 
GCCATTGGGG CTGCCTTTGG TGGGGAGAAC CGGCAGGGAG TGGTGTTTAT ATTCCCTGGG 
GGCCCAGGGG GTCTGGCGTC TAAGCCTTCC CAGGTTCTGC TGCCCCTGTG GGCAGCTGGC 
CACACACCGG ACTTCTTTGG CTCTGCCCTT CGAGGAGGCC GAGACCTAGA TGGCAATGGA 
TACCCTGATC TGATTGTGGG GTCCTTTGGT GTAGACAAGG CTGTGGTATA CAGGGGTCGC 
CCCATCGTGT CTGCCAGTGC CTCCCTCACC ATCTTTCCTG CCATGTTCAA CCCAGAGGAG 
CACAGCTGCA GCTTGGAGGG AAACCCTGTG ACTTGCATCA ACCTTAGCTT CTGCCTCAAT 
GCTTCCGGAA AACATGTTCC TGACTCCATC GGCTTCACGG TGGAGCTCCA GTTGGACTGG 
CAGAAGCAGA AGGGCGGGGT GCGGCGGGCG CTGTTCCTGG CCTCCCGACA GGCCACCCTG 
ACCCAGACCC TGCTCATCCA GAACGGGGCT CGGGAGGACT GCAGAGAGAT GAAGATCTAC 
CTCAGGAACG AGTCAGAGTT TCGAGATAAA CTCTCCCCGA TTCACATCGC CCTCAATTTC 
TCCCTGGACC CTCAAGCCCC AGTGGACAGC CACGGCCTCC GGCCAGTCCT ACACTACCAG 
AGCAAGAGCC GCATAGAGGA CAAGGCTCAG ATCTTGCTGG ACTGTGGAGA AGACAATATC 
TGTGTGCCAG ACCTACAGCT GGAAGTGTTT GGGGAGCAGA ACCACGTATA CCTGGGCGAC 
AAGAATTCTC TGAACCTCAC CTTCCACGCC CAGAATGTGG GTGAGGGTGG CGCCTACGAG 
GCAGAGCTTC GGGTCACAGC CCCTCCGGAG GCTGAGTACT CGGGACTCGT CAGACACCCA 
GGGAACTTCT CCAGCCTGAG CTGCGACTAC TTTGCTGTGA ACCAGAGTCG TCTGCTGGTG 
TGTGACCTGG GCAACCCCAT GAAGGCTGGG GCCAGTCTCT GGGGTGGCCT TCGGTTCACA 
GTCCCTCACC TCAGGGACAC GAAGAAAACC ATTCAGTTTG ACTTCCAGAT CCTCAGCAAG 
AATCTCAACA ACTCGCAAAG CGACGTGGTT TCCTTCCGGC TCTCGGTGGA GGCTCAGGCC 
CAGGTCTCTC TTAACGGTGT CTCCAAGCCC GAGGCAGTGC TATTTCCGAT GAGCGACTGG 
CATCCCCAAG ACCAGCCGCA GGAGGAGGGT GACGTGGGCC CTGCTGTCCA CCATGTCTAT 
GAGCTCATCA ACCTGGGCCC CAGCTCTATT AGCCAGGGCG TGTTGGAGCT CAGCTGTCCC 
CATGCTCTGG ATGGCCAGCA GCTCCTCTAC GTGACCAGGG TCACAGGACT CAGCAACTGC 
ACCACCAGTC ACCCCCCCAA CCCAGAGGGC CTGGAGTTGG ATCCTGAGGG TTCCCAGCAC 
CACCGGCTGC AAAGACGGGA TGTTCCAGGT CGGAGCCCTG CCTCCTCAGG GCCTCAGATT 
CTGAAATGCC CAGAGGCAGA GTGTTTCAAG CTGCGCTGTG AGCTGGGGCC ACTGCACCGG 
CAAGAGAGCC GAAGTCTGCA ACTGCATTTC CGTGTCTGGG CCAAGACCTT CCTACAGCGG 
GAGCACCAGC CATTTAGCCT GCAGTGTGAG GCCGTGTATG AAGCCCTGAA GATGCCCTAT 
AAAATCCTGC CTCGGCAGCT TCCCCAGAAG GCGCTGCAGG TGGCCACAGC TGTGCAGTGG 
ATCAAGGCAG AAGGCAGCCA CGGAGTCCCT CTCTGGATCA TTATCTTAGC CATCCTCATT 
GGCCTCCTGC TCCTCGGTCT GCTCATCTAT ATCCTCTACA AGCTCGGATT CTTCAAACGC 
TCCCTCCCGT ACGGCACCGC CATGGAAAAA GCTCAGCTCA AGCCTCCAGC CACCTCCGAT 
GCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024847121.1
CDS	890..4075
Translation	MVYGKGVKRLRQRSSQDGEVPPEPRVRAGPGPGEQSVLTILQGLSPLLLPDFQASHFPPTHPRAGQPDAWVLPREGPWLGSRGVSVLVGAPKANTSQPGVLQGGAVYLCPWGTSPAQCTPIEFDSKGSRIFESSTSSSEGEEPVEYKSLQWFGATVRAHGSSILACAPLYSWRTEKEPQSDPVGTCYLSTGNFTQILEYAPCRSDFSQEAGQGYCQGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQIAESYYPGYLINPVRGQLQTRQASSIYDDSYLGYSVAVGEFSGDDREDFVAGVPKGNLTYGYVTILNGSDIRSLYNFSGEQMASYFGYAVAATDINGDGLDDLLVGAPLLMERTADGRPQEVGRVYIYLQRLAGMEPTPTLTLTGQDEFGRFGSSLTPLGDLDQDGYNDVAIGAAFGGENRQGVVFIFPGGPGGLASKPSQVLLPLWAAGHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGRPIVSASASLTIFPAMFNPEEHSCSLEGNPVTCINLSFCLNASGKHVPDSIGFTVELQLDWQKQKGGVRRALFLASRQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIHIALNFSLDPQAPVDSHGLRPVLHYQSKSRIEDKAQILLDCGEDNICVPDLQLEVFGEQNHVYLGDKNSLNLTFHAQNVGEGGAYEAELRVTAPPEAEYSGLVRHPGNFSSLSCDYFAVNQSRLLVCDLGNPMKAGASLWGGLRFTVPHLRDTKKTIQFDFQILSKNLNNSQSDVVSFRLSVEAQAQVSLNGVSKPEAVLFPMSDWHPQDQPQEEGDVGPAVHHVYELINLGPSSISQGVLELSCPHALDGQQLLYVTRVTGLSNCTTSHPPNPEGLELDPEGSQHHRLQRRDVPGRSPASSGPQILKCPEAECFKLRCELGPLHRQESRSLQLHFRVWAKTFLQREHQPFSLQCEAVYEALKMPYKILPRQLPQKALQVATAVQWIKAEGSHGVPLWIIILAILIGLLLLGLLIYILYKLGFFKRSLPYGTAMEKAQLKPPATSDA

Target ORF information:

RefSeq Version	XM_024991353.1
Organism	Bos taurus(cattle)
Definition	Bos taurus integrin subunit alpha 5 (ITGA5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024991353.1

ORF Insert Sequence:

ATGGTGTATG GGAAAGGTGT TAAGAGGCTG AGACAAAGAT CCAGCCAGGA TGGGGAGGTC 
CCACCAGAGC CCAGGGTGAG GGCAGGCCCA GGCCCCGGGG AACAATCTGT TCTCACCATC 
CTCCAGGGCC TCTCTCCACT TCTACTGCCT GATTTCCAAG CCTCACATTT TCCTCCTACA 
CACCCCAGGG CTGGGCAGCC GGACGCCTGG GTCTTGCCCA GAGAAGGGCC TTGGCTTGGG 
AGCAGAGGGG TCAGCGTGCT GGTGGGGGCG CCCAAGGCTA ACACCAGCCA GCCGGGAGTG 
CTGCAGGGCG GTGCCGTCTA CCTCTGCCCC TGGGGCACCA GCCCGGCACA GTGCACCCCC 
ATTGAATTTG ACAGCAAAGG CTCTCGGATC TTCGAGTCCT CAACGTCCAG CTCAGAGGGA 
GAGGAGCCTG TGGAGTACAA GTCCCTGCAG TGGTTTGGAG CAACAGTGCG AGCCCATGGC 
TCCTCCATCC TGGCCTGTGC TCCCCTCTAC AGCTGGCGCA CCGAGAAGGA GCCGCAGAGT 
GATCCTGTGG GCACCTGCTA CCTCTCCACA GGCAACTTCA CCCAGATTCT GGAGTATGCA 
CCCTGCCGCT CAGATTTCAG CCAAGAAGCA GGACAGGGTT ACTGCCAAGG GGGCTTCAGT 
GCTGAGTTCA CCAAGACGGG GCGTGTGGTC CTGGGTGGAC CAGGGAGCTA TTTCTGGCAA 
GGCCAGATCC TGTCCGCCAC CCAGGAGCAG ATTGCAGAAT CCTATTATCC CGGGTACCTG 
ATCAACCCAG TTCGGGGGCA GCTGCAGACT CGCCAGGCCA GTTCCATCTA CGATGACAGC 
TACCTGGGAT ACTCTGTGGC TGTGGGTGAA TTCAGTGGTG ATGATAGAGA AGACTTCGTT 
GCTGGTGTGC CCAAAGGGAA CCTCACCTAT GGCTATGTCA CCATCCTTAA TGGCTCAGAC 
ATCCGGTCCC TCTACAACTT TTCAGGGGAA CAGATGGCCT CCTACTTTGG CTACGCAGTG 
GCCGCCACAG ACATCAACGG GGATGGGCTG GACGACTTGC TGGTAGGGGC GCCCCTGCTC 
ATGGAGCGGA CAGCCGACGG GCGGCCGCAG GAGGTGGGCA GGGTCTATAT CTACCTGCAG 
CGCCTGGCTG GCATGGAGCC CACGCCCACC CTGACCCTCA CTGGCCAGGA TGAGTTTGGC 
CGGTTCGGCA GCTCCCTGAC CCCCCTGGGG GACCTAGACC AGGATGGCTA CAATGATGTA 
GCCATTGGGG CTGCCTTTGG TGGGGAGAAC CGGCAGGGAG TGGTGTTTAT ATTCCCTGGG 
GGCCCAGGGG GTCTGGCGTC TAAGCCTTCC CAGGTTCTGC TGCCCCTGTG GGCAGCTGGC 
CACACACCGG ACTTCTTTGG CTCTGCCCTT CGAGGAGGCC GAGACCTAGA TGGCAATGGA 
TACCCTGATC TGATTGTGGG GTCCTTTGGT GTAGACAAGG CTGTGGTATA CAGGGGTCGC 
CCCATCGTGT CTGCCAGTGC CTCCCTCACC ATCTTTCCTG CCATGTTCAA CCCAGAGGAG 
CACAGCTGCA GCTTGGAGGG AAACCCTGTG ACTTGCATCA ACCTTAGCTT CTGCCTCAAT 
GCTTCCGGAA AACATGTTCC TGACTCCATC GGCTTCACGG TGGAGCTCCA GTTGGACTGG 
CAGAAGCAGA AGGGCGGGGT GCGGCGGGCG CTGTTCCTGG CCTCCCGACA GGCCACCCTG 
ACCCAGACCC TGCTCATCCA GAACGGGGCT CGGGAGGACT GCAGAGAGAT GAAGATCTAC 
CTCAGGAACG AGTCAGAGTT TCGAGATAAA CTCTCCCCGA TTCACATCGC CCTCAATTTC 
TCCCTGGACC CTCAAGCCCC AGTGGACAGC CACGGCCTCC GGCCAGTCCT ACACTACCAG 
AGCAAGAGCC GCATAGAGGA CAAGGCTCAG ATCTTGCTGG ACTGTGGAGA AGACAATATC 
TGTGTGCCAG ACCTACAGCT GGAAGTGTTT GGGGAGCAGA ACCACGTATA CCTGGGCGAC 
AAGAATTCTC TGAACCTCAC CTTCCACGCC CAGAATGTGG GTGAGGGTGG CGCCTACGAG 
GCAGAGCTTC GGGTCACAGC CCCTCCGGAG GCTGAGTACT CGGGACTCGT CAGACACCCA 
GGGAACTTCT CCAGCCTGAG CTGCGACTAC TTTGCTGTGA ACCAGAGTCG TCTGCTGGTG 
TGTGACCTGG GCAACCCCAT GAAGGCTGGG GCCAGTCTCT GGGGTGGCCT TCGGTTCACA 
GTCCCTCACC TCAGGGACAC GAAGAAAACC ATTCAGTTTG ACTTCCAGAT CCTCAGCAAG 
AATCTCAACA ACTCGCAAAG CGACGTGGTT TCCTTCCGGC TCTCGGTGGA GGCTCAGGCC 
CAGGTCTCTC TTAACGGTGT CTCCAAGCCC GAGGCAGTGC TATTTCCGAT GAGCGACTGG 
CATCCCCAAG ACCAGCCGCA GGAGGAGGGT GACGTGGGCC CTGCTGTCCA CCATGTCTAT 
GAGCTCATCA ACCTGGGCCC CAGCTCTATT AGCCAGGGCG TGTTGGAGCT CAGCTGTCCC 
CATGCTCTGG ATGGCCAGCA GCTCCTCTAC GTGACCAGGG TCACAGGACT CAGCAACTGC 
ACCACCAGTC ACCCCCCCAA CCCAGAGGGC CTGGAGTTGG ATCCTGAGGG TTCCCAGCAC 
CACCGGCTGC AAAGACGGGA TGTTCCAGGT CGGAGCCCTG CCTCCTCAGG GCCTCAGATT 
CTGAAATGCC CAGAGGCAGA GTGTTTCAAG CTGCGCTGTG AGCTGGGGCC ACTGCACCGG 
CAAGAGAGCC GAAGTCTGCA ACTGCATTTC CGTGTCTGGG CCAAGACCTT CCTACAGCGG 
GAGCACCAGC CATTTAGCCT GCAGTGTGAG GCCGTGTATG AAGCCCTGAA GATGCCCTAT 
AAAATCCTGC CTCGGCAGCT TCCCCAGAAG GCGCTGCAGG TGGCCACAGC TGTGCAGTGG 
ATCAAGGCAG AAGGCAGCCA CGGAGTCCCT CTCTGGATCA TTATCTTAGC CATCCTCATT 
GGCCTCCTGC TCCTCGGTCT GCTCATCTAT ATCCTCTACA AGCTCGGATT CTTCAAACGC 
TCCCTCCCGT ACGGCACCGC CATGGAAAAA GCTCAGCTCA AGCCTCCAGC CACCTCCGAT 
GCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

X-linked inhibitor of apoptosis protein controls alpha5-integrin-mediated cell adhesion and migration.
American journal of physiology. Heart and circulatory physiology299(2)H300-9(2010 Aug)
Kim J,Ahn S,Ko YG,Boo YC,Chi SG,Ni CW,Go YM,Jo H,Park H

Expression and putative function of fibronectin and its receptor (integrin alpha(5)beta(1)) in male and female gametes during bovine fertilization in vitro.
Reproduction (Cambridge, England)138(3)471-82(2009 Sep)
Thys M,Nauwynck H,Maes D,Hoogewijs M,Vercauteren D,Rijsselaere T,Favoreel H,Van Soom A

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Marçais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Matrix-specific suppression of integrin activation in shear stress signaling.
Molecular biology of the cell17(11)4686-97(2006 Nov)
Orr AW,Ginsberg MH,Shattil SJ,Deckmyn H,Schwartz MA

Regulation of Ca2+-dependent K+ current by alphavbeta3 integrin engagement in vascular endothelium.
The Journal of biological chemistry279(13)12959-66(2004 Mar)
Kawasaki J,Davis GE,Davis MJ

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ITGA5 cDNA ORF clone, Bos taurus(cattle)

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Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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