Oaz cDNA ORF clone, Bombyx mori(domestic silkworm)

Gene
Clones
gRNAs

Summary

Gene Symbol	Oaz
Entrez Gene ID	692580
Full Name	ornithine decarboxylase antizyme
Gene Type	protein-coding
Organism	Bombyx mori(domestic silkworm)
Summary	The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamine in cells. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis pathway; thus, completing the auto-regulatory circuit. This gene encodes an ornithine decarboxylase antizyme homolog that shares highest similarity with vertebrate antizyme 1, however, has a different and longer N-terminus, and is encoded by 7 exons compared to 5 in vertebrates. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jul 2014].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001043563.2	NP_001037028.1	ornithine decarboxylase antizyme

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Transcriptomic analysis of developmental features of Bombyx mori wing disc during metamorphosis.
Ou J, Deng HM, Zheng SC, Huang LH, Feng QL, Liu L
BMC genomics15820(2014 Sep)

Large scale full-length cDNA sequencing reveals a unique genomic landscape in a lepidopteran model insect, Bombyx mori.
Suetsugu Y, Futahashi R, Kanamori H, Kadono-Okuda K, Sasanuma S, Narukawa J, Ajimura M, Jouraku A, Namiki N, Shimomura M, Sezutsu H, Osanai-Futahashi M, Suzuki MG, Daimon T, Shinoda T, Taniai K, Asaoka K, Niwa R, Kawaoka S, Katsuma S, Tamura T, Noda H, Kasahara M, Sugano S, Suzuki Y, Fujiwara H, Kataoka H, Arunkumar KP, Tomar A, Nagaraju J, Goldsmith MR, Feng Q, Xia Q, Yamamoto K, Shimada T, Mita K
G3 (Bethesda, Md.)3(9)1481-92(2013 Sep)

Mass identification of transcriptional units expressed from the Bombyx mori nucleopolyhedrovirus genome.
Katsuma S, Kang W, Shin-i T, Ohishi K, Kadota K, Kohara Y, Shimada T
The Journal of general virology92(Pt 1)200-3(2011 Jan)

Antizyme expression: a subversion of triplet decoding, which is remarkably conserved by evolution, is a sensor for an autoregulatory circuit.
Ivanov IP, Gesteland RF, Atkins JF
Nucleic acids research28(17)3185-96(2000 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Oaz gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Oaz cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBg22321	NM_001043563.2 Latest version!	Bombyx mori ornithine decarboxylase antizyme (Oaz), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Oaz ( NM_001043563.2 ) cDNA ORF clone, Bombyx mori(domestic silkworm) -> NP_001037028.1 Bombyx mori ornithine decarboxylase antizyme (Oaz), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OBg22321
Clone ID Related Accession (Same CDS sequence)	NM_001043563.2
Accession Version	NM_001043563.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 786bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1556899200000
Organism	Bombyx mori(domestic silkworm)
Product	ornithine decarboxylase antizyme
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BY939458.1, AK378506.1, AF291575.1, FS849186.1, FY059138.1 and BABH01041439.1. On Jul 16, 2014 this sequence version replaced NM_001043563.1. Transcript Variant: This variant (1) represents the protein-coding transcript. ##Evidence-Data-START## Transcript exon combination :: AK378506.1, BP126236.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03699706, SAMN03699708 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## ribosomal slippage :: inferred from conservation ##RefSeq-Attributes-END##

ATGACGATGT TAATACAACA ATTAAATTGT AGTAGTAGTA TTAGTAAATA CTACAATGGA 
AATGGTGTGG ACTCCGTCGA GACCAAACAG GTCGAGAAGG TTTATTCCGG TGACGGGGCG 
TCTCTGAGCG CTCCCGGCAG CAAGCGCTCA GCTCTGTCGG CTTCGGACGC CGAGTGTTTC 
TCGCTGTGCC TGGGCGCCGG GCCTCTGTGG TGGTCCGATG TCCCTGCTCA CGGCTCTGCA 
CCGCCCGGAG GGGTGACCGG CGGGGCTGCG AGCCCCGCTA CCCCGGCCAC CCCCAACCAC 
GACGACAATC GCGACTTGCT AAGTGCCCTG CTATGGTCAA GCTCCAGCTC TTTGGCCAGC 
AGCGCCGAGA GTCTCCATGA TGGCCAAGCG TCTCCGCAAC AGCTACAACT ACAACAACAA 
GTTGTGAATA AGATCTTGGA GCGCAAGGAC AAGCACCCCG TTAAAATTGA GTTCAAGATT 
TATCTCACCG AGAACACAGT TATACGTTGG GAGGCTGTTG TGCACAACAA CATGATGTAC 
CTCCGCGTGC CCGGGGTCCT GCAGTCCGGC AGCAAGGACA GCTTCATGCT GCTCCTGGAT 
TTCGCTGAAG AGCGTCTCGG CTGTAAGAGT TGCATCATCT GCGTTTTGAA GAGTCGTCCC 
GACCGCGCTA CCCTGCTGCG CACCTTCATG TTCATGGGAT TCCAAGTTCT GGCTCCGAAT 
TCGCCGCTGA CCCCACAGCA CATCAACAAC CCTAATTACA TTTTCTTACA CTACAATATG 
CAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001037028.1
CDS	join(145..360,362..931)
Translation	MTMLIQQLNCSSSISKYYNGNGVDSVETKQVEKVYSGDGASLSAPGSKRSALSASDAECFSLCLGAGPLWWSDVPAHGSAPPGGVTGGAASPATPATPNHDDNRDLLSALLWSSSSSLASSAESLHDGQASPQQLQLQQQVVNKILERKDKHPVKIEFKIYLTENTVIRWEAVVHNNMMYLRVPGVLQSGSKDSFMLLLDFAEERLGCKSCIICVLKSRPDRATLLRTFMFMGFQVLAPNSPLTPQHINNPNYIFLHYNMQ

Target ORF information:

RefSeq Version	NM_001043563.2
Organism	Bombyx mori(domestic silkworm)
Definition	Bombyx mori ornithine decarboxylase antizyme (Oaz), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001043563.2

ORF Insert Sequence:

ATGACGATGT TAATACAACA ATTAAATTGT AGTAGTAGTA TTAGTAAATA CTACAATGGA 
AATGGTGTGG ACTCCGTCGA GACCAAACAG GTCGAGAAGG TTTATTCCGG TGACGGGGCG 
TCTCTGAGCG CTCCCGGCAG CAAGCGCTCA GCTCTGTCGG CTTCGGACGC CGAGTGTTTC 
TCGCTGTGCC TGGGCGCCGG GCCTCTGTGG TGGTCCGATG TCCCTGCTCA CGGCTCTGCA 
CCGCCCGGAG GGGTGACCGG CGGGGCTGCG AGCCCCGCTA CCCCGGCCAC CCCCAACCAC 
GACGACAATC GCGACTTGCT AAGTGCCCTG CTATGGTCAA GCTCCAGCTC TTTGGCCAGC 
AGCGCCGAGA GTCTCCATGA TGGCCAAGCG TCTCCGCAAC AGCTACAACT ACAACAACAA 
GTTGTGAATA AGATCTTGGA GCGCAAGGAC AAGCACCCCG TTAAAATTGA GTTCAAGATT 
TATCTCACCG AGAACACAGT TATACGTTGG GAGGCTGTTG TGCACAACAA CATGATGTAC 
CTCCGCGTGC CCGGGGTCCT GCAGTCCGGC AGCAAGGACA GCTTCATGCT GCTCCTGGAT 
TTCGCTGAAG AGCGTCTCGG CTGTAAGAGT TGCATCATCT GCGTTTTGAA GAGTCGTCCC 
GACCGCGCTA CCCTGCTGCG CACCTTCATG TTCATGGGAT TCCAAGTTCT GGCTCCGAAT 
TCGCCGCTGA CCCCACAGCA CATCAACAAC CCTAATTACA TTTTCTTACA CTACAATATG 
CAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Transcriptomic analysis of developmental features of Bombyx mori wing disc during metamorphosis.
BMC genomics15820(2014 Sep)
Ou J,Deng HM,Zheng SC,Huang LH,Feng QL,Liu L

Large scale full-length cDNA sequencing reveals a unique genomic landscape in a lepidopteran model insect, Bombyx mori.
G3 (Bethesda, Md.)3(9)1481-92(2013 Sep)
Suetsugu Y,Futahashi R,Kanamori H,Kadono-Okuda K,Sasanuma S,Narukawa J,Ajimura M,Jouraku A,Namiki N,Shimomura M,Sezutsu H,Osanai-Futahashi M,Suzuki MG,Daimon T,Shinoda T,Taniai K,Asaoka K,Niwa R,Kawaoka S,Katsuma S,Tamura T,Noda H,Kasahara M,Sugano S,Suzuki Y,Fujiwara H,Kataoka H,Arunkumar KP,Tomar A,Nagaraju J,Goldsmith MR,Feng Q,Xia Q,Yamamoto K,Shimada T,Mita K

Mass identification of transcriptional units expressed from the Bombyx mori nucleopolyhedrovirus genome.
The Journal of general virology92(Pt 1)200-3(2011 Jan)
Katsuma S,Kang W,Shin-i T,Ohishi K,Kadota K,Kohara Y,Shimada T

Antizyme expression: a subversion of triplet decoding, which is remarkably conserved by evolution, is a sensor for an autoregulatory circuit.
Nucleic acids research28(17)3185-96(2000 Sep)
Ivanov IP,Gesteland RF,Atkins JF

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Oaz cDNA ORF clone, Bombyx mori(domestic silkworm)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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