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Homo sapiens (human)

Browse by Letter Index, Genomic Locus


Melanin biosynthesis Biological oxidations
Sterols are 12-hydroxylated by CYP8B1 CYP2E1 reactions
Miscellaneous substrates PAOs oxidise polyamines to amines
Aflatoxin activation and detoxification Mitochondrial iron-sulfur cluster biogenesis
Erythrocytes take up carbon dioxide and release oxygen Erythrocytes take up oxygen and release carbon dioxide
Reversible hydration of carbon dioxide Cell-extracellular matrix interactions
Signal regulatory protein (SIRP) family interactions Crosslinking of collagen fibrils
Fibronectin matrix formation Activation of Matrix Metalloproteinases
Activation, translocation and oligomerization of BAX Release of apoptotic factors from the mitochondria
Apoptotic factor-mediated response SMAC binds to IAPs
Semaphorin interactions Sema3A PAK dependent Axon repulsion
CRMPs in Sema3A signaling NCAM signaling for neurite out-growth
Netrin-1 signaling L1CAM interactions
Signal transduction by L1 CHL1 interactions
EPH-Ephrin signaling EPHA-mediated growth cone collapse
EPH-ephrin mediated repulsion of cells Myogenesis
Regulation of beta-cell development Transcriptional regulation of white adipocyte differentiation
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation Base Excision Repair
Cleavage of the damaged purine Displacement of DNA glycosylase by APEX1
Resolution of AP sites via the multiple-nucleotide patch replacement pathway MGMT-mediated DNA damage reversal
ALKBH3 mediated reversal of alkylation damage Mismatch Repair
Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha Detoxification of Reactive Oxygen Species
HSF1 activation Oxidative Stress Induced Senescence
Formation of Senescence-Associated Heterochromatin Foci (SAHF) Macroautophagy
HATs acetylate histones Abortive elongation of HIV-1 transcript in the absence of Tat
HIV elongation arrest and recovery Formation of HIV elongation complex in the absence of HIV Tat
Pausing and recovery of HIV elongation Toxicity of botulinum toxin type C (BoNT/C)
Uptake and function of diphtheria toxin Amyloid fiber formation
CD28 dependent PI3K/Akt signaling Signaling by the B Cell Receptor (BCR)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Downstream signaling events of B Cell Receptor (BCR)
AKT phosphorylates targets in the nucleus Negative regulation of the PI3K/AKT network
Antigen processing: Ubiquitination & Proteasome degradation IRAK2 mediated activation of TAK1 complex
Toll Like Receptor 3 (TLR3) Cascade TRIF-mediated TLR3/TLR4 signaling
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling Initial triggering of complement
Creation of C4 and C2 activators The NLRP3 inflammasome
Advanced glycosylation endproduct receptor signaling Negative regulators of RIG-I/MDA5 signaling
Beta defensins IRF3-mediated induction of type I IFN
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production RAF activation
Negative regulation of MAPK pathway PKA-mediated phosphorylation of CREB
FCERI mediated MAPK activation Regulation of IFNA signaling
Interferon gamma signaling Interleukin receptor SHC signaling
Interleukin-3, 5 and GM-CSF signaling Interleukin-7 signaling
TNFR2 non-canonical NF-kB pathway Reproduction
Sperm:Oocyte Membrane Binding Platelet homeostasis
Prostacyclin signalling through prostacyclin receptor Elevation of cytosolic Ca2+ levels
Signal amplification Platelet Aggregation (Plug Formation)
Arachidonate production from DAG Common Pathway of Fibrin Clot Formation
PECAM1 interactions GAB1 signalosome
FGFR1b ligand binding and activation FGFR1c and Klotho ligand binding and activation
FRS-mediated FGFR1 signaling PI-3K cascade:FGFR1
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