ORF » Species Summary » Homo sapiens » Reactome

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Homo sapiens (human)

Browse by Letter Index, Genomic Locus


Negative regulation of FGFR1 signaling FGFR2b ligand binding and activation
FRS-mediated FGFR2 signaling Phospholipase C-mediated cascade; FGFR2
Signaling by FGFR3 FGFR3 ligand binding and activation
Downstream signaling of activated FGFR3 SHC-mediated cascade:FGFR3
Negative regulation of FGFR3 signaling betaKlotho-mediated ligand binding
SHC-mediated cascade:FGFR4 Signaling by Insulin receptor
IRS-mediated signalling PI3K Cascade
Inhibition of TSC complex formation by PKB Signalling by NGF
NRAGE signals death through JNK NF-kB is activated and signals survival
Ceramide signalling p75NTR regulates axonogenesis
Axonal growth inhibition (RHOA activation) ARMS-mediated activation
PLC-gamma1 signalling Phosphorylation of Emi1
APC-Cdc20 mediated degradation of Nek2A APC/C:Cdc20 mediated degradation of Cyclin B
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Chromosome Maintenance
Extension of Telomeres Processive synthesis on the C-strand of the telomere
Meiotic synapsis NR1D1 (REV-ERBA) represses gene expression
trans-Golgi Network Vesicle Budding Oncogenic MAPK signaling
Signaling by RAS mutants Signaling by BRAF and RAF fusions
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models MET Receptor Activation
MET activates RAS signaling MET activates PTPN11
MET activates PTK2 signaling Activation of the TFAP2 (AP-2) family of transcription factors
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation rRNA processing in the mitochondrion
Interactions of neurexins and neuroligins at synapses VLDL biosynthesis
Pyrophosphate hydrolysis Ovarian tumor domain proteases
Intestinal infectious diseases Protein methylation
G1/S DNA Damage Checkpoints p53-Dependent G1 DNA Damage Response
Stabilization of p53 Amplification of signal from the kinetochores
Inactivation of APC/C via direct inhibition of the APC/C complex Cell Cycle, Mitotic
G0 and Early G1 G1/S Transition
SCF(Skp2)-mediated degradation of p27/p21 Polymerase switching
Removal of the Flap Intermediate Regulation of DNA replication
G2/M Transition Polo-like kinase mediated events
Loss of Nlp from mitotic centrosomes Activation of NIMA Kinases NEK9, NEK6, NEK7
Depolymerisation of the Nuclear Lamina Assembly of the pre-replicative complex
APC/C-mediated degradation of cell cycle proteins Regulation of APC/C activators between G1/S and early anaphase
Phosphorylation of the APC/C Nucleosome assembly
Telomere C-strand (Lagging Strand) Synthesis Meiosis
BMAL1:CLOCK,NPAS2 activates circadian gene expression Lysosome Vesicle Biogenesis
Transport of connexins along the secretory pathway Transport of connexons to the plasma membrane
Formation of annular gap junctions c-src mediated regulation of Cx43 function and closure of gap junctions
Scavenging by Class A Receptors Transmembrane transport of small molecules
Multifunctional anion exchangers Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
Sodium-coupled sulphate, di- and tri-carboxylate transporters Transport of vitamins, nucleosides, and related molecules
Aquaporin-mediated transport Transport of glycerol from adipocytes to the liver by Aquaporins
Ion transport by P-type ATPases Metabolism of carbohydrates
Glycolysis Fructose metabolism
Galactose catabolism Glycosaminoglycan metabolism
HS-GAG biosynthesis Dermatan sulfate biosynthesis
Metabolism of lipids and lipoproteins Lipid digestion, mobilization, and transport
Triglyceride Biosynthesis Import of palmitoyl-CoA into the mitochondrial matrix
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