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Homo sapiens (human)

Browse by Letter Index, Genomic Locus


Constitutive Signaling by Aberrant PI3K in Cancer TGFBR2 MSI Frameshift Mutants in Cancer
TGFBR1 KD Mutants in Cancer truncated APC mutants destabilize the destruction complex
S33 mutants of beta-catenin aren't phosphorylated XAV939 inhibits tankyrase, stabilizing AXIN
Biosynthesis of A2E, implicated in retinal degradation Defective CUBN causes hereditary megaloblastic anemia 1
Defective TCN2 causes hereditary megaloblastic anemia Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
Diseases associated with glycosaminoglycan metabolism Defective B3GAT3 causes JDSSDHD
Defective EXT2 causes exostoses 2 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
COPI-mediated anterograde transport SUMOylation of chromatin organization proteins
Phase 0 - rapid depolarisation Ion homeostasis
B-WICH complex positively regulates rRNA expression Defective ABCC8 can cause hypoglycemias and hyperglycemias
Interleukin-6 family signaling Methylation of MeSeH for excretion
Response to metal ions The role of GTSE1 in G2/M progression after G2 checkpoint
Interaction between PHLDA1 and AURKA FGFRL1 modulation of FGFR1 signaling
PTK6 Down-Regulation Interleukin-12 signaling
Golgi-to-ER retrograde transport COPI-dependent Golgi-to-ER retrograde traffic
Signaling by FGFR3 point mutants in cancer Diseases associated with O-glycosylation of proteins
Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1 TP53 Regulates Transcription of DNA Repair Genes
Regulation of TP53 Activity through Acetylation ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
rRNA processing Cargo concentration in the ER
Synthesis of wybutosine at G37 of tRNA(Phe) TNFR1-induced NFkappaB signaling pathway
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Gap-filling DNA repair synthesis and ligation in GG-NER
Gap-filling DNA repair synthesis and ligation in TC-NER Defective SFTPA2 causes idiopathic pulmonary fibrosis (IPF)
Regulation of gap junction activity Translocation of GLUT4 to the plasma membrane
Binding and Uptake of Ligands by Scavenger Receptors Scavenging by Class B Receptors
Scavenging by Class F Receptors ABC-family proteins mediated transport
Mitochondrial ABC transporters Type II Na+/Pi cotransporters
Glucose transport Regulation of Glucokinase by Glucokinase Regulatory Protein
Facilitative Na+-independent glucose transporters Proton-coupled monocarboxylate transport
Na+/Cl- dependent neurotransmitter transporters Organic cation/anion/zwitterion transport
Organic cation transport Organic anion transport
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane Transport of fatty acids
Iron uptake and transport Ion channel transport
Miscellaneous transport and binding events Fructose catabolism
Lactose synthesis Pentose phosphate pathway (hexose monophosphate shunt)
Transport and synthesis of PAPS Keratan sulfate degradation
Heparan sulfate/heparin (HS-GAG) metabolism A tetrasaccharide linker sequence is required for GAG synthesis
CS/DS degradation Inositol phosphate metabolism
Chylomicron-mediated lipid transport LDL-mediated lipid transport
Fatty Acyl-CoA Biosynthesis Synthesis of very long-chain fatty acyl-CoAs
Beta oxidation of palmitoyl-CoA to myristoyl-CoA Beta oxidation of octanoyl-CoA to hexanoyl-CoA
Synthesis of Ketone Bodies Beta-oxidation of pristanoyl-CoA
Synthesis of bile acids and bile salts via 27-hydroxycholesterol Acyl chain remodelling of PE
PI and PC transport between ER and Golgi membranes Acyl chain remodelling of PC
Acyl chain remodelling of PG Synthesis of CL
Synthesis of PIPs at the late endosome membrane Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Ubiquinol biosynthesis Regulation of insulin secretion
PKA activation in glucagon signalling Citric acid cycle (TCA cycle)
The fatty acid cycling model The proton buffering model
Purine catabolism Metabolism of vitamins and cofactors
Vitamin B5 (pantothenate) metabolism Sulfur amino acid metabolism
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