DMA cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	DMA
Entrez Gene ID	417050
Full Name	major histocompatibility complex, class II, DM alpha
Synonyms	B-DMA,B-MA1,BMA1,DMA,DMA1,HLA-DMA,MHC-DMA
General protein information	Preferred Names major histocompatibility complex, class II, DM alpha Names B locus M alpha chain 1 MHC class II M alpha chain MHC class II antigen
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001099353.2	NP_001092823.1	B locus M alpha chain 1 precursor

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	MAMU-DMA	XP_002803735.1
Homo sapiens (human)	HLA-DMA	NP_006111.2
Bos taurus (cattle)	BOLA-DMA	NP_001012692.2
Mus musculus (house mouse)	H2-DMa	NP_034516.3
Gallus gallus (chicken)	BMA1	NP_001092823.1
Pan troglodytes (chimpanzee)	MAMU-DMA	XP_003311254.1

Gene Ontology
Bibliography

Related articles in PubMed

Organisation and diversity of the class II DM region of the chicken MHC.
Chazara O, Tixier-Boichard M, Morin V, Zoorob R, Bed'hom B
Molecular immunology48(9-10)1263-71(2011 May)

BG1 has a major role in MHC-linked resistance to malignant lymphoma in the chicken.
Goto RM, Wang Y, Taylor RL Jr, Wakenell PS, Hosomichi K, Shiina T, Blackmore CS, Briles WE, Miller MM
Proceedings of the National Academy of Sciences of the United States of America106(39)16740-5(2009 Sep)

Contribution of mutation, recombination, and gene conversion to chicken MHC-B haplotype diversity.
Hosomichi K, Miller MM, Goto RM, Wang Y, Suzuki S, Kulski JK, Nishibori M, Inoko H, Hanzawa K, Shiina T
Journal of immunology (Baltimore, Md. : 1950)181(5)3393-9(2008 Sep)

Extended gene map reveals tripartite motif, C-type lectin, and Ig superfamily type genes within a subregion of the chicken MHC-B affecting infectious disease.
Shiina T, Briles WE, Goto RM, Hosomichi K, Yanagiya K, Shimizu S, Inoko H, Miller MM
Journal of immunology (Baltimore, Md. : 1950)178(11)7162-72(2007 Jun)

A molecular map of the chicken major histocompatibility complex: the class II beta genes are closely linked to the class I genes and the nucleolar organizer.
Guillemot F, Billault A, Pourquié O, Béhar G, Chaussé AM, Zoorob R, Kreibich G, Auffray C
The EMBO journal7(9)2775-85(1988 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following DMA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DMA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa26255	NM_001099353.2 Latest version!	Gallus gallus major histocompatibility complex, class II, DM alpha (DMA), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DMA ( NM_001099353.2 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001092823.1 Gallus gallus major histocompatibility complex, class II, DM alpha (DMA), mRNA.

Price & Availability↑

CloneID	OGa26255
Clone ID Related Accession (Same CDS sequence)	NM_001099353.2
Accession Version	NM_001099353.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 792bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1557504000000
Organism	Gallus gallus(chicken)
Product	B locus M alpha chain 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AADN05001139.1. On Apr 30, 2011 this sequence version replaced NM_001099353.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BU120638.1, HAEK01202069.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2201357, SAMEA2201358 [ECO:0000348] ##Evidence-Data-END##

ATGGGGGCTG CGAGCGGGCG CGGGGCGCTC GTGGCAGCGC TGCTGGGGGC GGCCCTGGGG 
AGCGTCAGAG CCGAGCCATC ACTGCACACT CTGTCCGAGG TGCTCTTCTG CCAGCCGGAC 
ACGCCGTCGC TGGGGCTGTC AGTGGCCTTC GACTCAGAGC AGCTCTTCTC ATTCGATGTC 
CCCAACTCGC AGTGGCTGCC GCAGCTCCCC GATGGCCCCT CGTGGCCCGC AGACATCGAG 
CAGCCCCACG AGCTGCTGCA CGACGCCGCG CTGTGCCGTG AGCTGCTCGA TTTGCTCACC 
AGAATCGCCA CCGGGCCAAA CCCAATGCCT GAAGCCAAGG GCATCCCGGT GGCCGATGTC 
TTCCTGCAGC AGCCTCTGCA GCTCGGCTAC CCCAACACTC TGATCTGTAT GGTGGGCAAC 
ATCTTCCCCC CAGCCATCAC TATCAGCTGG CAGCGGGATG GCATCCCCGT CACCGATGGC 
GTCACCCACC TCACCTACAC CCCCACCGAG GACCTGGGCT TCATGCGCTT CTCCTACCTG 
GCGGTGACAC CGCACTCTGG TGACATCTAT GCCTGCATTG TCACCCGCGA GAGGGACAAC 
ATCTCTGTGG TGGCTTACTG GGTGCCACAG GACCCCATCC CTTCGGACGT GTTGGCCACG 
GCGGTGTGCG GCGCAGTGAC GGCGCTGGGC ATCCTGCTGG CACTGCTGGG TTTGGGGCTG 
CTGCTGTCCG CCCGCCGGCG CAGTATGTGG GGACAATGGA GACAGCAGGG ACACCCGCCC 
CGTACTCACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001092823.1
CDS	55..846
Translation	MGAASGRGALVAALLGAALGSVRAEPSLHTLSEVLFCQPDTPSLGLSVAFDSEQLFSFDVPNSQWLPQLPDGPSWPADIEQPHELLHDAALCRELLDLLTRIATGPNPMPEAKGIPVADVFLQQPLQLGYPNTLICMVGNIFPPAITISWQRDGIPVTDGVTHLTYTPTEDLGFMRFSYLAVTPHSGDIYACIVTRERDNISVVAYWVPQDPIPSDVLATAVCGAVTALGILLALLGLGLLLSARRRSMWGQWRQQGHPPRTH

Target ORF information:

RefSeq Version	NM_001099353.2
Organism	Gallus gallus(chicken)
Definition	Gallus gallus major histocompatibility complex, class II, DM alpha (DMA), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001099353.2

ORF Insert Sequence:

ATGGGGGCTG CGAGCGGGCG CGGGGCGCTC GTGGCAGCGC TGCTGGGGGC GGCCCTGGGG 
AGCGTCAGAG CCGAGCCATC ACTGCACACT CTGTCCGAGG TGCTCTTCTG CCAGCCGGAC 
ACGCCGTCGC TGGGGCTGTC AGTGGCCTTC GACTCAGAGC AGCTCTTCTC ATTCGATGTC 
CCCAACTCGC AGTGGCTGCC GCAGCTCCCC GATGGCCCCT CGTGGCCCGC AGACATCGAG 
CAGCCCCACG AGCTGCTGCA CGACGCCGCG CTGTGCCGTG AGCTGCTCGA TTTGCTCACC 
AGAATCGCCA CCGGGCCAAA CCCAATGCCT GAAGCCAAGG GCATCCCGGT GGCCGATGTC 
TTCCTGCAGC AGCCTCTGCA GCTCGGCTAC CCCAACACTC TGATCTGTAT GGTGGGCAAC 
ATCTTCCCCC CAGCCATCAC TATCAGCTGG CAGCGGGATG GCATCCCCGT CACCGATGGC 
GTCACCCACC TCACCTACAC CCCCACCGAG GACCTGGGCT TCATGCGCTT CTCCTACCTG 
GCGGTGACAC CGCACTCTGG TGACATCTAT GCCTGCATTG TCACCCGCGA GAGGGACAAC 
ATCTCTGTGG TGGCTTACTG GGTGCCACAG GACCCCATCC CTTCGGACGT GTTGGCCACG 
GCGGTGTGCG GCGCAGTGAC GGCGCTGGGC ATCCTGCTGG CACTGCTGGG TTTGGGGCTG 
CTGCTGTCCG CCCGCCGGCG CAGTATGTGG GGACAATGGA GACAGCAGGG ACACCCGCCC 
CGTACTCACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Organisation and diversity of the class II DM region of the chicken MHC.
Molecular immunology48(9-10)1263-71(2011 May)
Chazara O,Tixier-Boichard M,Morin V,Zoorob R,Bed'hom B

BG1 has a major role in MHC-linked resistance to malignant lymphoma in the chicken.
Proceedings of the National Academy of Sciences of the United States of America106(39)16740-5(2009 Sep)
Goto RM,Wang Y,Taylor RL Jr,Wakenell PS,Hosomichi K,Shiina T,Blackmore CS,Briles WE,Miller MM

Contribution of mutation, recombination, and gene conversion to chicken MHC-B haplotype diversity.
Journal of immunology (Baltimore, Md. : 1950)181(5)3393-9(2008 Sep)
Hosomichi K,Miller MM,Goto RM,Wang Y,Suzuki S,Kulski JK,Nishibori M,Inoko H,Hanzawa K,Shiina T

Extended gene map reveals tripartite motif, C-type lectin, and Ig superfamily type genes within a subregion of the chicken MHC-B affecting infectious disease.
Journal of immunology (Baltimore, Md. : 1950)178(11)7162-72(2007 Jun)
Shiina T,Briles WE,Goto RM,Hosomichi K,Yanagiya K,Shimizu S,Inoko H,Miller MM

A molecular map of the chicken major histocompatibility complex: the class II beta genes are closely linked to the class I genes and the nucleolar organizer.
The EMBO journal7(9)2775-85(1988 Sep)
Guillemot F,Billault A,Pourquié O,Béhar G,Chaussé AM,Zoorob R,Kreibich G,Auffray C

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DMA cDNA ORF clone, Gallus gallus(chicken)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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