TOX cDNA ORF clone, Danio rerio(Zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	TOX
Entrez Gene ID	569666
Full Name	thymocyte selection-associated high mobility group box
Synonyms	sb:eu868,si:ch211-198j13.2
General protein information	Preferred Names thymocyte selection-associated high mobility group box Names thymocyte selection-associated high mobility group box protein TOX
Gene Type	protein-coding
Organism	Danio rerio(Zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001256694.1	NP_001243623.1	thymocyte selection-associated high mobility group box protein TOX
XM_005163360.3	XP_005163417.1	thymocyte selection-associated high mobility group box protein TOX isoform X1
XM_009298496.2	XP_009296771.1	thymocyte selection-associated high mobility group box protein TOX isoform X2

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Tox	NP_001102124.1
Danio rerio (zebrafish)	tox	NP_001243623.1
Mus musculus (house mouse)	Tox	NP_663757.3
Homo sapiens (human)	TOX	NP_055544.1
Canis lupus familiaris (dog)	TOX	XP_544093.3
Pan troglodytes (chimpanzee)	TOX	XP_519777.2
Macaca mulatta (Rhesus monkey)	TOX	XP_001088869.1
Bos taurus (cattle)	TOX	NP_001095566.1
Gallus gallus (chicken)	TOX	NP_001026196.1
Xenopus tropicalis (tropical clawed frog)	tox	XP_002936155.2

Gene Ontology
Bibliography

Related articles in PubMed

TOX Regulates Growth, DNA Repair, and Genomic Instability in T-cell Acute Lymphoblastic Leukemia.
Lobbardi R, Pinder J, Martinez-Pastor B, Theodorou M, Blackburn JS, Abraham BJ, Namiki Y, Mansour M, Abdelfattah NS, Molodtsov A, Alexe G, Toiber D, de Waard M, Jain E, Boukhali M, Lion M, Bhere D, Shah K, Gutierrez A, Stegmaier K, Silverman LB, Sadreyev RI, Asara JM, Oettinger MA, Haas W, Look AT, Young RA, Mostoslavsky R, Dellaire G, Langenau DM
Cancer discovery7(11)1336-1353(2017 11)

Transcriptome analysis of pancreatic cells across distant species highlights novel important regulator genes.
Tarifeño-Saldivia E, Lavergne A, Bernard A, Padamata K, Bergemann D, Voz ML, Manfroid I, Peers B
BMC biology15(1)21(2017 03)

Single-cell transcriptional analysis of normal, aberrant, and malignant hematopoiesis in zebrafish.
Moore FE, Garcia EG, Lobbardi R, Jain E, Tang Q, Moore JC, Cortes M, Molodtsov A, Kasheta M, Luo CC, Garcia AJ, Mylvaganam R, Yoder JA, Blackburn JS, Sadreyev RI, Ceol CJ, North TE, Langenau DM
The Journal of experimental medicine213(6)979-92(2016 05)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TOX gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TOX cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ODa34519	NM_001256694.1 Latest version!	Danio rerio thymocyte selection-associated high mobility group box (tox), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ODa06917	XM_005163360.3 Latest version!	Danio rerio thymocyte selection-associated high mobility group box (tox), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ODa45823	XM_009298496.2 Latest version!	Danio rerio thymocyte selection-associated high mobility group box (tox), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TOX ( NM_001256694.1 ) cDNA ORF clone, Danio rerio(Zebrafish) -> NP_001243623.1 Danio rerio thymocyte selection-associated high mobility group box (tox), mRNA.

Price & Availability↑

CloneID	ODa34519
Clone ID Related Accession (Same CDS sequence)	NM_001256694.1
Accession Version	NM_001256694.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1623bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1542902400000
Organism	Danio rerio(zebrafish)
Product	thymocyte selection-associated high mobility group box protein TOX
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CT956055.9 and CR450692.5. On Feb 17, 2012 this sequence version replaced XM_001919504.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGGACGTGA GATTTTATCC ACAACCTCCA CCACCATCAG CAACAGATCC TTCCCGACTG 
GGACAGTCGC ACTATTCGGA CTCTCCGTAT TGCAATAAGT ACGACAGTGA AAACATGTTC 
ATGAGTATGC CAGAGCCCGG CCAGGACTTT GTGCCAGGGA ACCAGTTCCG CGTTCCTGCG 
AGTCCCAGCC AGACGCAGCA CAGCAACAAA CAGGCCGGCG GACACTGGAA AAGAGAGACC 
CAGACACACA CGGATGGCCA TCGTCTCACA TGGCAGTCAT ACCCAGTGCC CAGTCTTGGG 
GATGAAGACT TCAACATCCC ACCCATCACC CCTCCAACCC TCCCAGAACA CATGCTGGCA 
CACCTTCCCG AGTCTGAATC CGGGACATAC CACCCCCTGT GCCCCCCTGT GTCCCAGAAT 
GGACTGCACC CCTTTCACCT GCAAGGAATG GACCTGCCCG GCATGTTGAG TCCTAATATG 
TTGAGCCAAG ATGGCAGCCT GCTCACCAAC TCTCTCTCAG TGATGCAGCA GATGGTGAAC 
TCAGACTCGC GTTACGGTGG TCACCCTCAG GTGGACACAC TCAGACCCAG AGTCCAGCCA 
GGCATGGGTC CTCCTCAAGG TCAGCTGACC ACTATCAACC AATCACAGCT CAACGCCCAA 
CTGGGTCTGA ACGGCAACAA TGGCACCCAT GGGTCTCCAT CTCCACCAGA GAGCAAATCT 
GCCACACCGT CGCCCTCCAG CTCCGTGCAT GAGGACGATG CCGATGATGC TGCCAAGATA 
AACGGGGCAG AAAAGAGAGC AGCCACAGAC ATGGCCAAGA AGCCCAAAAC CCCCAAGAAG 
AAGAAGAAGA AAGACCCGAA CGAGCCCCAG AAGCCCGTGT CAGCCTACGC CCTGTTCTTC 
AGAGACACAC AGGCAGCCAT TAAGGGACAA AACCCCAACG CCACGTTCGG GGAGGTTTCC 
AAAATAGTGG CTTCCATGTG GGACGGCCTG GGCGAAGAAC AGAAACAGGT GTACAAGAAA 
AAAACAGAAA CAGCAAAGAA GGAGTACCTC AAACAGCTGG CTGCGTACAG AGCAAGCCTC 
GTGTCTCAGA GCTATAATGA CCCGGGTGAT GTGAAGGCGT CCCAAGCCTC TCAGATGCTT 
GGGCCCAAGC CACCAGTGTT CTCCGGAGCA GGCCAGACTC ATCCAGGTCT CTACATGGCT 
CCTCCCTACC ACCAGCAGCC AGGACTCAGT TCCCATCTGC CCCCAATGCA GCCAGGCTTG 
TCCCGAGGTG GAGCATCCCG GCCTGGAGCA GTGAGCATGA GCAGCATGAC TGGATCGTCT 
CCTCCACCAC TGCAGATCAG CCCACCGTTA CACCAGCACC TCAGTCTCCA CCACCAGCAG 
CAGCAGCAGC AGATCGGCAG CCACACATTG GCCCTGCACT CGCCATCCAT GGCCCAGGGT 
TTCCCCCTTC AGGCAGAGTA TCAGAGCATG GTAAATGTCA CATCCTCCGC CGGACCTGGT 
CTCTCCCCCT CAATGGACTA CCGCACCGGC TGCAGGAATG GACCGACCCA GGGCCTGGAA 
TGGTCCCCTG ACTACTGCGG CAACGGGTCT CTGCAGAGGG ATAAAGCCCT GTACCTGACC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001243623.1
CDS	348..1970
Translation	MDVRFYPQPPPPSATDPSRLGQSHYSDSPYCNKYDSENMFMSMPEPGQDFVPGNQFRVPASPSQTQHSNKQAGGHWKRETQTHTDGHRLTWQSYPVPSLGDEDFNIPPITPPTLPEHMLAHLPESESGTYHPLCPPVSQNGLHPFHLQGMDLPGMLSPNMLSQDGSLLTNSLSVMQQMVNSDSRYGGHPQVDTLRPRVQPGMGPPQGQLTTINQSQLNAQLGLNGNNGTHGSPSPPESKSATPSPSSSVHEDDADDAAKINGAEKRAATDMAKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQVYKKKTETAKKEYLKQLAAYRASLVSQSYNDPGDVKASQASQMLGPKPPVFSGAGQTHPGLYMAPPYHQQPGLSSHLPPMQPGLSRGGASRPGAVSMSSMTGSSPPPLQISPPLHQHLSLHHQQQQQQIGSHTLALHSPSMAQGFPLQAEYQSMVNVTSSAGPGLSPSMDYRTGCRNGPTQGLEWSPDYCGNGSLQRDKALYLT

Target ORF information:

RefSeq Version	NM_001256694.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio thymocyte selection-associated high mobility group box (tox), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001256694.1

ORF Insert Sequence:

ATGGACGTGA GATTTTATCC ACAACCTCCA CCACCATCAG CAACAGATCC TTCCCGACTG 
GGACAGTCGC ACTATTCGGA CTCTCCGTAT TGCAATAAGT ACGACAGTGA AAACATGTTC 
ATGAGTATGC CAGAGCCCGG CCAGGACTTT GTGCCAGGGA ACCAGTTCCG CGTTCCTGCG 
AGTCCCAGCC AGACGCAGCA CAGCAACAAA CAGGCCGGCG GACACTGGAA AAGAGAGACC 
CAGACACACA CGGATGGCCA TCGTCTCACA TGGCAGTCAT ACCCAGTGCC CAGTCTTGGG 
GATGAAGACT TCAACATCCC ACCCATCACC CCTCCAACCC TCCCAGAACA CATGCTGGCA 
CACCTTCCCG AGTCTGAATC CGGGACATAC CACCCCCTGT GCCCCCCTGT GTCCCAGAAT 
GGACTGCACC CCTTTCACCT GCAAGGAATG GACCTGCCCG GCATGTTGAG TCCTAATATG 
TTGAGCCAAG ATGGCAGCCT GCTCACCAAC TCTCTCTCAG TGATGCAGCA GATGGTGAAC 
TCAGACTCGC GTTACGGTGG TCACCCTCAG GTGGACACAC TCAGACCCAG AGTCCAGCCA 
GGCATGGGTC CTCCTCAAGG TCAGCTGACC ACTATCAACC AATCACAGCT CAACGCCCAA 
CTGGGTCTGA ACGGCAACAA TGGCACCCAT GGGTCTCCAT CTCCACCAGA GAGCAAATCT 
GCCACACCGT CGCCCTCCAG CTCCGTGCAT GAGGACGATG CCGATGATGC TGCCAAGATA 
AACGGGGCAG AAAAGAGAGC AGCCACAGAC ATGGCCAAGA AGCCCAAAAC CCCCAAGAAG 
AAGAAGAAGA AAGACCCGAA CGAGCCCCAG AAGCCCGTGT CAGCCTACGC CCTGTTCTTC 
AGAGACACAC AGGCAGCCAT TAAGGGACAA AACCCCAACG CCACGTTCGG GGAGGTTTCC 
AAAATAGTGG CTTCCATGTG GGACGGCCTG GGCGAAGAAC AGAAACAGGT GTACAAGAAA 
AAAACAGAAA CAGCAAAGAA GGAGTACCTC AAACAGCTGG CTGCGTACAG AGCAAGCCTC 
GTGTCTCAGA GCTATAATGA CCCGGGTGAT GTGAAGGCGT CCCAAGCCTC TCAGATGCTT 
GGGCCCAAGC CACCAGTGTT CTCCGGAGCA GGCCAGACTC ATCCAGGTCT CTACATGGCT 
CCTCCCTACC ACCAGCAGCC AGGACTCAGT TCCCATCTGC CCCCAATGCA GCCAGGCTTG 
TCCCGAGGTG GAGCATCCCG GCCTGGAGCA GTGAGCATGA GCAGCATGAC TGGATCGTCT 
CCTCCACCAC TGCAGATCAG CCCACCGTTA CACCAGCACC TCAGTCTCCA CCACCAGCAG 
CAGCAGCAGC AGATCGGCAG CCACACATTG GCCCTGCACT CGCCATCCAT GGCCCAGGGT 
TTCCCCCTTC AGGCAGAGTA TCAGAGCATG GTAAATGTCA CATCCTCCGC CGGACCTGGT 
CTCTCCCCCT CAATGGACTA CCGCACCGGC TGCAGGAATG GACCGACCCA GGGCCTGGAA 
TGGTCCCCTG ACTACTGCGG CAACGGGTCT CTGCAGAGGG ATAAAGCCCT GTACCTGACC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOX ( XM_005163360.3 ) cDNA ORF clone, Danio rerio(Zebrafish) -> XP_005163417.1 Danio rerio thymocyte selection-associated high mobility group box (tox), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa06917
Clone ID Related Accession (Same CDS sequence)	XM_005163360.3
Accession Version	XM_005163360.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1620bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1497369600000
Organism	Danio rerio(zebrafish)
Product	thymocyte selection-associated high mobility group box protein TOX isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007113.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XM_005163360.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACGTGA GATTTTATCC ACAACCTCCA CCACCATCAG CAACAGATCC TTCCCGACTG 
GGACAGTCGC ACTATTCGGA CTCTCCGTAT TGCAATAAGT ACGACAGTGA AAACATGTTC 
ATGAGTATGC CAGAGCCCGG CCAGGACTTT GTGCCAGGGA ACCAGTTCCG CGTTCCTGCG 
AGTCCCAGCC AGACGCAGCA CAGCAACAAA CAGGCCGGCG GACACTGGAA AAGAGAGACC 
CAGACACACA CGGATGGCCA TCGTCTCACA TGGTCATACC CAGTGCCCAG TCTTGGGGAT 
GAAGACTTCA ACATCCCACC CATCACCCCT CCAACCCTCC CAGAACACAT GCTGGCACAC 
CTTCCCGAGT CTGAATCCGG GACATACCAC CCCCTGTGCC CCCCTGTGTC CCAGAATGGA 
CTGCACCCCT TTCACCTGCA AGGAATGGAC CTGCCCGGCA TGTTGAGTCC TAATATGTTG 
AGCCAAGATG GCAGCCTGCT CACCAACTCT CTCTCAGTGA TGCAGCAGAT GGTGAACTCA 
GACTCGCGTT ACGGTGGTCA CCCTCAGGTG GACACACTCA GACCCAGAGT CCAGCCAGGC 
ATGGGTCCTC CTCAAGGTCA GCTGACCACT ATCAACCAAT CACAGCTCAA CGCCCAACTG 
GGTCTGAACG GCAACAATGG CACCCATGGG TCTCCATCTC CACCAGAGAG CAAATCTGCC 
ACACCGTCGC CCTCCAGCTC CGTGCATGAG GACGATGCCG ATGATGCTGC CAAGATAAAC 
GGGGCAGAAA AGAGAGCAGC CACAGACATG GCCAAGAAGC CCAAAACCCC CAAGAAGAAG 
AAGAAGAAAG ACCCGAACGA GCCCCAGAAG CCCGTGTCAG CCTACGCCCT GTTCTTCAGA 
GACACACAGG CAGCCATTAA GGGACAAAAC CCCAACGCCA CGTTCGGGGA GGTTTCCAAA 
ATAGTGGCTT CCATGTGGGA CGGCCTGGGC GAAGAACAGA AACAGGTGTA CAAGAAAAAA 
ACAGAAACAG CAAAGAAGGA GTACCTCAAA CAGCTGGCTG CGTACAGAGC AAGCCTCGTG 
TCTCAGAGCT ATAATGACCC GGGTGATGTG AAGGCGTCCC AAGCCTCTCA GATGCTTGGG 
CCCAAGCCAC CAGTGTTCTC CGGAGCAGGC CAGACTCATC CAGGTCTCTA CATGGCTCCT 
CCCTACCACC AGCAGCCAGG ACTCAGTTCC CATCTGCCCC CAATGCAGCC AGGCTTGTCC 
CGAGGTGGAG CATCCCGGCC TGGAGCAGTG AGCATGAGCA GCATGACTGG ATCGTCTCCT 
CCACCACTGC AGATCAGCCC ACCGTTACAC CAGCACCTCA GTCTCCACCA CCAGCAGCAG 
CAGCAGCAGA TCGGCAGCCA CACATTGGCC CTGCACTCGC CATCCATGGC CCAGGGTTTC 
CCCCTTCAGG CAGAGTATCA GAGCATGGTA AATGTCACAT CCTCCGCCGG ACCTGGTCTC 
TCCCCCTCAA TGGACTACCG CACCGGCTGC AGGAATGGAC CGACCCAGGG CCTGGAATGG 
TCCCCTGACT ACTGCGGCAA CGGGTCTCTG CAGAGGGATA AAGCCCTGTA CCTGACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005163417.1
CDS	356..1975
Translation	MDVRFYPQPPPPSATDPSRLGQSHYSDSPYCNKYDSENMFMSMPEPGQDFVPGNQFRVPASPSQTQHSNKQAGGHWKRETQTHTDGHRLTWSYPVPSLGDEDFNIPPITPPTLPEHMLAHLPESESGTYHPLCPPVSQNGLHPFHLQGMDLPGMLSPNMLSQDGSLLTNSLSVMQQMVNSDSRYGGHPQVDTLRPRVQPGMGPPQGQLTTINQSQLNAQLGLNGNNGTHGSPSPPESKSATPSPSSSVHEDDADDAAKINGAEKRAATDMAKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQVYKKKTETAKKEYLKQLAAYRASLVSQSYNDPGDVKASQASQMLGPKPPVFSGAGQTHPGLYMAPPYHQQPGLSSHLPPMQPGLSRGGASRPGAVSMSSMTGSSPPPLQISPPLHQHLSLHHQQQQQQIGSHTLALHSPSMAQGFPLQAEYQSMVNVTSSAGPGLSPSMDYRTGCRNGPTQGLEWSPDYCGNGSLQRDKALYLT

Target ORF information:

RefSeq Version	XM_005163360.3
Organism	Danio rerio(zebrafish)
Definition	Danio rerio thymocyte selection-associated high mobility group box (tox), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005163360.3

ORF Insert Sequence:

ATGGACGTGA GATTTTATCC ACAACCTCCA CCACCATCAG CAACAGATCC TTCCCGACTG 
GGACAGTCGC ACTATTCGGA CTCTCCGTAT TGCAATAAGT ACGACAGTGA AAACATGTTC 
ATGAGTATGC CAGAGCCCGG CCAGGACTTT GTGCCAGGGA ACCAGTTCCG CGTTCCTGCG 
AGTCCCAGCC AGACGCAGCA CAGCAACAAA CAGGCCGGCG GACACTGGAA AAGAGAGACC 
CAGACACACA CGGATGGCCA TCGTCTCACA TGGTCATACC CAGTGCCCAG TCTTGGGGAT 
GAAGACTTCA ACATCCCACC CATCACCCCT CCAACCCTCC CAGAACACAT GCTGGCACAC 
CTTCCCGAGT CTGAATCCGG GACATACCAC CCCCTGTGCC CCCCTGTGTC CCAGAATGGA 
CTGCACCCCT TTCACCTGCA AGGAATGGAC CTGCCCGGCA TGTTGAGTCC TAATATGTTG 
AGCCAAGATG GCAGCCTGCT CACCAACTCT CTCTCAGTGA TGCAGCAGAT GGTGAACTCA 
GACTCGCGTT ACGGTGGTCA CCCTCAGGTG GACACACTCA GACCCAGAGT CCAGCCAGGC 
ATGGGTCCTC CTCAAGGTCA GCTGACCACT ATCAACCAAT CACAGCTCAA CGCCCAACTG 
GGTCTGAACG GCAACAATGG CACCCATGGG TCTCCATCTC CACCAGAGAG CAAATCTGCC 
ACACCGTCGC CCTCCAGCTC CGTGCATGAG GACGATGCCG ATGATGCTGC CAAGATAAAC 
GGGGCAGAAA AGAGAGCAGC CACAGACATG GCCAAGAAGC CCAAAACCCC CAAGAAGAAG 
AAGAAGAAAG ACCCGAACGA GCCCCAGAAG CCCGTGTCAG CCTACGCCCT GTTCTTCAGA 
GACACACAGG CAGCCATTAA GGGACAAAAC CCCAACGCCA CGTTCGGGGA GGTTTCCAAA 
ATAGTGGCTT CCATGTGGGA CGGCCTGGGC GAAGAACAGA AACAGGTGTA CAAGAAAAAA 
ACAGAAACAG CAAAGAAGGA GTACCTCAAA CAGCTGGCTG CGTACAGAGC AAGCCTCGTG 
TCTCAGAGCT ATAATGACCC GGGTGATGTG AAGGCGTCCC AAGCCTCTCA GATGCTTGGG 
CCCAAGCCAC CAGTGTTCTC CGGAGCAGGC CAGACTCATC CAGGTCTCTA CATGGCTCCT 
CCCTACCACC AGCAGCCAGG ACTCAGTTCC CATCTGCCCC CAATGCAGCC AGGCTTGTCC 
CGAGGTGGAG CATCCCGGCC TGGAGCAGTG AGCATGAGCA GCATGACTGG ATCGTCTCCT 
CCACCACTGC AGATCAGCCC ACCGTTACAC CAGCACCTCA GTCTCCACCA CCAGCAGCAG 
CAGCAGCAGA TCGGCAGCCA CACATTGGCC CTGCACTCGC CATCCATGGC CCAGGGTTTC 
CCCCTTCAGG CAGAGTATCA GAGCATGGTA AATGTCACAT CCTCCGCCGG ACCTGGTCTC 
TCCCCCTCAA TGGACTACCG CACCGGCTGC AGGAATGGAC CGACCCAGGG CCTGGAATGG 
TCCCCTGACT ACTGCGGCAA CGGGTCTCTG CAGAGGGATA AAGCCCTGTA CCTGACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOX ( XM_009298496.2 ) cDNA ORF clone, Danio rerio(Zebrafish) -> XP_009296771.1 Danio rerio thymocyte selection-associated high mobility group box (tox), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ODa45823
Clone ID Related Accession (Same CDS sequence)	XM_009298496.2
Accession Version	XM_009298496.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1581bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466611200000
Organism	Danio rerio(Zebrafish)
Product	thymocyte selection-associated high mobility group box protein TOX isoform X2
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007113.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XM_009298496.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGGGCAG CAGTCTGTTT GTATCTGCTG TTGTATCGTT CACATGATGC CATGATGTAC 
GACAGTGAAA ACATGTTCAT GAGTATGCCA GAGCCCGGCC AGGACTTTGT GCCAGGGAAC 
CAGTTCCGCG TTCCTGCGAG TCCCAGCCAG ACGCAGCACA GCAACAAACA GGCCGGCGGA 
CACTGGAAAA GAGAGACCCA GACACACACG GATGGCCATC GTCTCACATG GCAGTCATAC 
CCAGTGCCCA GTCTTGGGGA TGAAGACTTC AACATCCCAC CCATCACCCC TCCAACCCTC 
CCAGAACACA TGCTGGCACA CCTTCCCGAG TCTGAATCCG GGACATACCA CCCCCTGTGC 
CCCCCTGTGT CCCAGAATGG ACTGCACCCC TTTCACCTGC AAGGAATGGA CCTGCCCGGC 
ATGTTGAGTC CTAATATGTT GAGCCAAGAT GGCAGCCTGC TCACCAACTC TCTCTCAGTG 
ATGCAGCAGA TGGTGAACTC AGACTCGCGT TACGGTGGTC ACCCTCAGGT GGACACACTC 
AGACCCAGAG TCCAGCCAGG CATGGGTCCT CCTCAAGGTC AGCTGACCAC TATCAACCAA 
TCACAGCTCA ACGCCCAACT GGGTCTGAAC GGCAACAATG GCACCCATGG GTCTCCATCT 
CCACCAGAGA GCAAATCTGC CACACCGTCG CCCTCCAGCT CCGTGCATGA GGACGATGCC 
GATGATGCTG CCAAGATAAA CGGGGCAGAA AAGAGAGCAG CCACAGACAT GGCCAAGAAG 
CCCAAAACCC CCAAGAAGAA GAAGAAGAAA GACCCGAACG AGCCCCAGAA GCCCGTGTCA 
GCCTACGCCC TGTTCTTCAG AGACACACAG GCAGCCATTA AGGGACAAAA CCCCAACGCC 
ACGTTCGGGG AGGTTTCCAA AATAGTGGCT TCCATGTGGG ACGGCCTGGG CGAAGAACAG 
AAACAGGTGT ACAAGAAAAA AACAGAAACA GCAAAGAAGG AGTACCTCAA ACAGCTGGCT 
GCGTACAGAG CAAGCCTCGT GTCTCAGAGC TATAATGACC CGGGTGATGT GAAGGCGTCC 
CAAGCCTCTC AGATGCTTGG GCCCAAGCCA CCAGTGTTCT CCGGAGCAGG CCAGACTCAT 
CCAGGTCTCT ACATGGCTCC TCCCTACCAC CAGCAGCCAG GACTCAGTTC CCATCTGCCC 
CCAATGCAGC CAGGCTTGTC CCGAGGTGGA GCATCCCGGC CTGGAGCAGT GAGCATGAGC 
AGCATGACTG GATCGTCTCC TCCACCACTG CAGATCAGCC CACCGTTACA CCAGCACCTC 
AGTCTCCACC ACCAGCAGCA GCAGCAGCAG ATCGGCAGCC ACACATTGGC CCTGCACTCG 
CCATCCATGG CCCAGGGTTT CCCCCTTCAG GCAGAGTATC AGAGCATGGT AAATGTCACA 
TCCTCCGCCG GACCTGGTCT CTCCCCCTCA ATGGACTACC GCACCGGCTG CAGGAATGGA 
CCGACCCAGG GCCTGGAATG GTCCCCTGAC TACTGCGGCA ACGGGTCTCT GCAGAGGGAT 
AAAGCCCTGT ACCTGACCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_009296771.1
CDS	16..1596
Translation	MRAAVCLYLLLYRSHDAMMYDSENMFMSMPEPGQDFVPGNQFRVPASPSQTQHSNKQAGGHWKRETQTHTDGHRLTWQSYPVPSLGDEDFNIPPITPPTLPEHMLAHLPESESGTYHPLCPPVSQNGLHPFHLQGMDLPGMLSPNMLSQDGSLLTNSLSVMQQMVNSDSRYGGHPQVDTLRPRVQPGMGPPQGQLTTINQSQLNAQLGLNGNNGTHGSPSPPESKSATPSPSSSVHEDDADDAAKINGAEKRAATDMAKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQVYKKKTETAKKEYLKQLAAYRASLVSQSYNDPGDVKASQASQMLGPKPPVFSGAGQTHPGLYMAPPYHQQPGLSSHLPPMQPGLSRGGASRPGAVSMSSMTGSSPPPLQISPPLHQHLSLHHQQQQQQIGSHTLALHSPSMAQGFPLQAEYQSMVNVTSSAGPGLSPSMDYRTGCRNGPTQGLEWSPDYCGNGSLQRDKALYLT

Target ORF information:

RefSeq Version	XM_009298496.2
Organism	Danio rerio(Zebrafish)
Definition	Danio rerio thymocyte selection-associated high mobility group box (tox), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_009298496.2

ORF Insert Sequence:

ATGCGGGCAG CAGTCTGTTT GTATCTGCTG TTGTATCGTT CACATGATGC CATGATGTAC 
GACAGTGAAA ACATGTTCAT GAGTATGCCA GAGCCCGGCC AGGACTTTGT GCCAGGGAAC 
CAGTTCCGCG TTCCTGCGAG TCCCAGCCAG ACGCAGCACA GCAACAAACA GGCCGGCGGA 
CACTGGAAAA GAGAGACCCA GACACACACG GATGGCCATC GTCTCACATG GCAGTCATAC 
CCAGTGCCCA GTCTTGGGGA TGAAGACTTC AACATCCCAC CCATCACCCC TCCAACCCTC 
CCAGAACACA TGCTGGCACA CCTTCCCGAG TCTGAATCCG GGACATACCA CCCCCTGTGC 
CCCCCTGTGT CCCAGAATGG ACTGCACCCC TTTCACCTGC AAGGAATGGA CCTGCCCGGC 
ATGTTGAGTC CTAATATGTT GAGCCAAGAT GGCAGCCTGC TCACCAACTC TCTCTCAGTG 
ATGCAGCAGA TGGTGAACTC AGACTCGCGT TACGGTGGTC ACCCTCAGGT GGACACACTC 
AGACCCAGAG TCCAGCCAGG CATGGGTCCT CCTCAAGGTC AGCTGACCAC TATCAACCAA 
TCACAGCTCA ACGCCCAACT GGGTCTGAAC GGCAACAATG GCACCCATGG GTCTCCATCT 
CCACCAGAGA GCAAATCTGC CACACCGTCG CCCTCCAGCT CCGTGCATGA GGACGATGCC 
GATGATGCTG CCAAGATAAA CGGGGCAGAA AAGAGAGCAG CCACAGACAT GGCCAAGAAG 
CCCAAAACCC CCAAGAAGAA GAAGAAGAAA GACCCGAACG AGCCCCAGAA GCCCGTGTCA 
GCCTACGCCC TGTTCTTCAG AGACACACAG GCAGCCATTA AGGGACAAAA CCCCAACGCC 
ACGTTCGGGG AGGTTTCCAA AATAGTGGCT TCCATGTGGG ACGGCCTGGG CGAAGAACAG 
AAACAGGTGT ACAAGAAAAA AACAGAAACA GCAAAGAAGG AGTACCTCAA ACAGCTGGCT 
GCGTACAGAG CAAGCCTCGT GTCTCAGAGC TATAATGACC CGGGTGATGT GAAGGCGTCC 
CAAGCCTCTC AGATGCTTGG GCCCAAGCCA CCAGTGTTCT CCGGAGCAGG CCAGACTCAT 
CCAGGTCTCT ACATGGCTCC TCCCTACCAC CAGCAGCCAG GACTCAGTTC CCATCTGCCC 
CCAATGCAGC CAGGCTTGTC CCGAGGTGGA GCATCCCGGC CTGGAGCAGT GAGCATGAGC 
AGCATGACTG GATCGTCTCC TCCACCACTG CAGATCAGCC CACCGTTACA CCAGCACCTC 
AGTCTCCACC ACCAGCAGCA GCAGCAGCAG ATCGGCAGCC ACACATTGGC CCTGCACTCG 
CCATCCATGG CCCAGGGTTT CCCCCTTCAG GCAGAGTATC AGAGCATGGT AAATGTCACA 
TCCTCCGCCG GACCTGGTCT CTCCCCCTCA ATGGACTACC GCACCGGCTG CAGGAATGGA 
CCGACCCAGG GCCTGGAATG GTCCCCTGAC TACTGCGGCA ACGGGTCTCT GCAGAGGGAT 
AAAGCCCTGT ACCTGACCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

TOX Regulates Growth, DNA Repair, and Genomic Instability in T-cell Acute Lymphoblastic Leukemia.
Cancer discovery7(11)1336-1353(2017 11)
Lobbardi R,Pinder J,Martinez-Pastor B,Theodorou M,Blackburn JS,Abraham BJ,Namiki Y,Mansour M,Abdelfattah NS,Molodtsov A,Alexe G,Toiber D,de Waard M,Jain E,Boukhali M,Lion M,Bhere D,Shah K,Gutierrez A,Stegmaier K,Silverman LB,Sadreyev RI,Asara JM,Oettinger MA,Haas W,Look AT,Young RA,Mostoslavsky R,Dellaire G,Langenau DM

Transcriptome analysis of pancreatic cells across distant species highlights novel important regulator genes.
BMC biology15(1)21(2017 03)
Tarifeño-Saldivia E,Lavergne A,Bernard A,Padamata K,Bergemann D,Voz ML,Manfroid I,Peers B

Single-cell transcriptional analysis of normal, aberrant, and malignant hematopoiesis in zebrafish.
The Journal of experimental medicine213(6)979-92(2016 05)
Moore FE,Garcia EG,Lobbardi R,Jain E,Tang Q,Moore JC,Cortes M,Molodtsov A,Kasheta M,Luo CC,Garcia AJ,Mylvaganam R,Yoder JA,Blackburn JS,Sadreyev RI,Ceol CJ,North TE,Langenau DM

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

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TOX cDNA ORF clone, Danio rerio(Zebrafish)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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