klhl40a cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	klhl40a
Entrez Gene ID	553257
Full Name	kelch-like family member 40a
Synonyms	kbtbd5,kbtbd5a
General protein information	Preferred Names kelch-like family member 40a Names kelch-like protein 40a kelch repeat and BTB (POZ) domain containing 5 kelch repeat and BTB (POZ) domain containing 5a kelch repeat and BTB domain-containing protein 5a kelch-like 40a
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001128682.1	NP_001122154.1	kelch-like protein 40a

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	KBTBD5	XP_002802877.1
Gallus gallus (chicken)	KBTBD5	XP_418495.2
Danio rerio (zebrafish)	klhl40a	NP_001122154.1
Xenopus tropicalis (tropical clawed frog)	klhl40	NP_001015817.1
Rattus norvegicus (Norway rat)	Klhl40	NP_001101665.1
Danio rerio (zebrafish)	klhl40b	XP_001334076.1
Homo sapiens (human)	KLHL40	NP_689606.2
Canis lupus familiaris (dog)	KLHL40	XP_542735.4
Bos taurus (cattle)	KBTBD5	NP_001015598.1
Mus musculus (house mouse)	Klhl40	NP_082478.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

Mutations in KLHL40 are a frequent cause of severe autosomal-recessive nemaline myopathy.
Ravenscroft G, Miyatake S, Lehtokari VL, Todd EJ, Vornanen P, Yau KS, Hayashi YK, Miyake N, Tsurusaki Y, Doi H, Saitsu H, Osaka H, Yamashita S, Ohya T, Sakamoto Y, Koshimizu E, Imamura S, Yamashita M, Ogata K, Shiina M, Bryson-Richardson RJ, Vaz R, Ceyhan O, Brownstein CA, Swanson LC, Monnot S, Romero NB, Amthor H, Kresoje N, Sivadorai P, Kiraly-Borri C, Haliloglu G, Talim B, Orhan D, Kale G, Charles AK, Fabian VA, Davis MR, Lammens M, Sewry CA, Manzur A, Muntoni F, Clarke NF, North KN, Bertini E, Nevo Y, Willichowski E, Silberg IE, Topaloglu H, Beggs AH, Allcock RJ, Nishino I, Wallgren-Pettersson C, Matsumoto N, Laing NG
American journal of human genetics93(1)6-18(2013 Jul)

Saltatory evolution of the ectodermal neural cortex gene family at the vertebrate origin.
Feiner N, Murakami Y, Breithut L, Mazan S, Meyer A, Kuraku S
Genome biology and evolution5(8)1485-502(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following klhl40a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the klhl40a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa02928	NM_001128682.1 Latest version!	Danio rerio kelch-like family member 40a (klhl40a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

klhl40a ( NM_001128682.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001122154.1 Danio rerio kelch-like family member 40a (klhl40a), mRNA.

Price & Availability↑

CloneID	ODa02928
Clone ID Related Accession (Same CDS sequence)	NM_001128682.1
Accession Version	NM_001128682.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1839bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577289600000
Organism	Danio rerio(zebrafish)
Product	kelch-like protein 40a
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC163267.1. On Jul 31, 2008 this sequence version replaced XM_684087.3. ##Evidence-Data-START## Transcript exon combination :: BC163267.1, BC078427.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168447, SAMEA3505370 [ECO:0000350] ##Evidence-Data-END##

ATGGCCTCCA TGTCAGTAGA CCCGGTGACG GAGCCACGGA TGTACCAGCA AACGCTTCTA 
CAAGATGGAC TCTGTGATCT CCTGGACGCA AACAAGTTTG TGGACTGCAT TTTGAAGATT 
AAGGACAAAG AGTTTCCTTG CCATCGGCTA GTGCTGGCCG CTACCAGCCC ATACTTCAAA 
GCCATGTTCC TGTCAGACCT GGAGGAGAGC AAAAAGCGGG AGATTGTTCT AAAGGACATC 
GAACCTGGCA TCATGGGAAT GATCCTGAGG TACATTTACA CCTCGGATAT CAACCTAACA 
GAGCAGAACG TCCAGGACAT TTTCATGGCG GCCAACATGT ATCAGATCCC ATCGATCTTT 
AGCGTGTGTG TGTCGTATCT CCAGCAAAAG CTGGTTCTCA GTAACTGTCT GGCTATCTTC 
AGGCTGGGAC TCTTGCTGGA CTGTCCACGT TTGGCCATGG AGGCACGGGA CTTCATTTGC 
GACCGGTATC TCCTGATCAT CAGAGACCAA GACTTCCATC AGTTGGGTCC CAGTGAGTTG 
GCTGCGATCA TCACATGTGA CTCCCTGAAT GTGGAGCGAG AAGAGTCTGT CTTTGAATCT 
CTCATGGACT GGGTGGAGTA CGACACAGAT GAGAGAACTA AAGAACTACC CGAACTTCTA 
CACTGTGTAC GTTTCCGTCT CATGCCGACA AGTTACTTTA AAGAGAAAGT CGAGGGGCAC 
CGATTGATTA GGACCAATCA GGAGCTCAAG AAGGAACTCC AGTTGATTAA GGATGCACAG 
AAAGGACTGC TTCACAGGGT CAAAAGGTCA TCACACAGGA AGGAAGGGAA GTCTGCTGAG 
TTTGAGTCTG ACGATGACGA TGAGGACGGT TTGCTGCCAG GGATCCTAAA TGACAACCCA 
CGTTTTGGGA TGTTTCAGTC GGACCTTATA TTGATGATTA ACGATGCAGG AACTGTTGCG 
TATGATGTTG GTGCAAACGA GTGCTTTGTG GCATCTTCAT CCACAGAGAT CCCTAAGAAC 
CACTGCAGTC TTGTGACGAA GGAAAATCAG ATCTTTGTCG TTGGAGGTCT GAGATACAAC 
GAGGAGAACA AAGATCAGCC CTTCAGTTCA TACTTTCTTC AGTTTGATCC CATGAGCTCT 
GAATGGCTAG GGATGCCGTC ACTCCCAAAC CCTCGCTGTC TGTTCGGCCT GGTGGAGGCT 
GAGAACTCCA TCTATGTGGT GGGAGGAAAA GAGCTGAAGG AGGGAGAGCG TGCACTGGAT 
TCTGTTATGA TCTACGACAG ACAGTCATTC AAATGGGGAG AGTCTGACCC TCTTCCTTAT 
GCAGTTTATG GCCATGGAAT CGTTTCCCAC AAAGGATTGG TCTACGTGAT TGGTGGGAAA 
ACTGAGAGCA AGAAATGTCT GAGGAGAGTG TGTGTCTACG ACCCCTCGAA GTTTGAATGG 
AAGGATCTGG CACCTATGAA AACAGCCCGC TCTCTGTTCG GCACTGCTGT TCACAAAAAC 
AAAATCTACG TGGTGACTGG AGTCACTGAC AACGGCCTGA CTAGCACAGT GGAGGTCTAT 
GACATCGCTA GCAATTCCTG GTCAGAGTTT GTGGACTTCC CTCAGGAGAG AAGCTCTCTT 
AACCTAGTTG AACTTGGTGG CTTTTTATAC GCTATCGGTG GGTTTGCTAT GATGCCTAAT 
GAGACTACAG AAAAGCTGGA GCCCACTGAA ATGAACGACA TATGGAAGTT TGATGAGGAG 
GAGAACTGCT GGAACGGGAT CCTGAGGGAG ATCCGCTATG CTGCAGGGGC CACAGTGCTT 
GGAGTGCGAC TGAATACCTT GAGACTTACA AAGATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001122154.1
CDS	41..1879
Translation	MASMSVDPVTEPRMYQQTLLQDGLCDLLDANKFVDCILKIKDKEFPCHRLVLAATSPYFKAMFLSDLEESKKREIVLKDIEPGIMGMILRYIYTSDINLTEQNVQDIFMAANMYQIPSIFSVCVSYLQQKLVLSNCLAIFRLGLLLDCPRLAMEARDFICDRYLLIIRDQDFHQLGPSELAAIITCDSLNVEREESVFESLMDWVEYDTDERTKELPELLHCVRFRLMPTSYFKEKVEGHRLIRTNQELKKELQLIKDAQKGLLHRVKRSSHRKEGKSAEFESDDDDEDGLLPGILNDNPRFGMFQSDLILMINDAGTVAYDVGANECFVASSSTEIPKNHCSLVTKENQIFVVGGLRYNEENKDQPFSSYFLQFDPMSSEWLGMPSLPNPRCLFGLVEAENSIYVVGGKELKEGERALDSVMIYDRQSFKWGESDPLPYAVYGHGIVSHKGLVYVIGGKTESKKCLRRVCVYDPSKFEWKDLAPMKTARSLFGTAVHKNKIYVVTGVTDNGLTSTVEVYDIASNSWSEFVDFPQERSSLNLVELGGFLYAIGGFAMMPNETTEKLEPTEMNDIWKFDEEENCWNGILREIRYAAGATVLGVRLNTLRLTKI

Target ORF information:

RefSeq Version	NM_001128682.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio kelch-like family member 40a (klhl40a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001128682.1

ORF Insert Sequence:

ATGGCCTCCA TGTCAGTAGA CCCGGTGACG GAGCCACGGA TGTACCAGCA AACGCTTCTA 
CAAGATGGAC TCTGTGATCT CCTGGACGCA AACAAGTTTG TGGACTGCAT TTTGAAGATT 
AAGGACAAAG AGTTTCCTTG CCATCGGCTA GTGCTGGCCG CTACCAGCCC ATACTTCAAA 
GCCATGTTCC TGTCAGACCT GGAGGAGAGC AAAAAGCGGG AGATTGTTCT AAAGGACATC 
GAACCTGGCA TCATGGGAAT GATCCTGAGG TACATTTACA CCTCGGATAT CAACCTAACA 
GAGCAGAACG TCCAGGACAT TTTCATGGCG GCCAACATGT ATCAGATCCC ATCGATCTTT 
AGCGTGTGTG TGTCGTATCT CCAGCAAAAG CTGGTTCTCA GTAACTGTCT GGCTATCTTC 
AGGCTGGGAC TCTTGCTGGA CTGTCCACGT TTGGCCATGG AGGCACGGGA CTTCATTTGC 
GACCGGTATC TCCTGATCAT CAGAGACCAA GACTTCCATC AGTTGGGTCC CAGTGAGTTG 
GCTGCGATCA TCACATGTGA CTCCCTGAAT GTGGAGCGAG AAGAGTCTGT CTTTGAATCT 
CTCATGGACT GGGTGGAGTA CGACACAGAT GAGAGAACTA AAGAACTACC CGAACTTCTA 
CACTGTGTAC GTTTCCGTCT CATGCCGACA AGTTACTTTA AAGAGAAAGT CGAGGGGCAC 
CGATTGATTA GGACCAATCA GGAGCTCAAG AAGGAACTCC AGTTGATTAA GGATGCACAG 
AAAGGACTGC TTCACAGGGT CAAAAGGTCA TCACACAGGA AGGAAGGGAA GTCTGCTGAG 
TTTGAGTCTG ACGATGACGA TGAGGACGGT TTGCTGCCAG GGATCCTAAA TGACAACCCA 
CGTTTTGGGA TGTTTCAGTC GGACCTTATA TTGATGATTA ACGATGCAGG AACTGTTGCG 
TATGATGTTG GTGCAAACGA GTGCTTTGTG GCATCTTCAT CCACAGAGAT CCCTAAGAAC 
CACTGCAGTC TTGTGACGAA GGAAAATCAG ATCTTTGTCG TTGGAGGTCT GAGATACAAC 
GAGGAGAACA AAGATCAGCC CTTCAGTTCA TACTTTCTTC AGTTTGATCC CATGAGCTCT 
GAATGGCTAG GGATGCCGTC ACTCCCAAAC CCTCGCTGTC TGTTCGGCCT GGTGGAGGCT 
GAGAACTCCA TCTATGTGGT GGGAGGAAAA GAGCTGAAGG AGGGAGAGCG TGCACTGGAT 
TCTGTTATGA TCTACGACAG ACAGTCATTC AAATGGGGAG AGTCTGACCC TCTTCCTTAT 
GCAGTTTATG GCCATGGAAT CGTTTCCCAC AAAGGATTGG TCTACGTGAT TGGTGGGAAA 
ACTGAGAGCA AGAAATGTCT GAGGAGAGTG TGTGTCTACG ACCCCTCGAA GTTTGAATGG 
AAGGATCTGG CACCTATGAA AACAGCCCGC TCTCTGTTCG GCACTGCTGT TCACAAAAAC 
AAAATCTACG TGGTGACTGG AGTCACTGAC AACGGCCTGA CTAGCACAGT GGAGGTCTAT 
GACATCGCTA GCAATTCCTG GTCAGAGTTT GTGGACTTCC CTCAGGAGAG AAGCTCTCTT 
AACCTAGTTG AACTTGGTGG CTTTTTATAC GCTATCGGTG GGTTTGCTAT GATGCCTAAT 
GAGACTACAG AAAAGCTGGA GCCCACTGAA ATGAACGACA TATGGAAGTT TGATGAGGAG 
GAGAACTGCT GGAACGGGAT CCTGAGGGAG ATCCGCTATG CTGCAGGGGC CACAGTGCTT 
GGAGTGCGAC TGAATACCTT GAGACTTACA AAGATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

Mutations in KLHL40 are a frequent cause of severe autosomal-recessive nemaline myopathy.
American journal of human genetics93(1)6-18(2013 Jul)
Ravenscroft G,Miyatake S,Lehtokari VL,Todd EJ,Vornanen P,Yau KS,Hayashi YK,Miyake N,Tsurusaki Y,Doi H,Saitsu H,Osaka H,Yamashita S,Ohya T,Sakamoto Y,Koshimizu E,Imamura S,Yamashita M,Ogata K,Shiina M,Bryson-Richardson RJ,Vaz R,Ceyhan O,Brownstein CA,Swanson LC,Monnot S,Romero NB,Amthor H,Kresoje N,Sivadorai P,Kiraly-Borri C,Haliloglu G,Talim B,Orhan D,Kale G,Charles AK,Fabian VA,Davis MR,Lammens M,Sewry CA,Manzur A,Muntoni F,Clarke NF,North KN,Bertini E,Nevo Y,Willichowski E,Silberg IE,Topaloglu H,Beggs AH,Allcock RJ,Nishino I,Wallgren-Pettersson C,Matsumoto N,Laing NG

Saltatory evolution of the ectodermal neural cortex gene family at the vertebrate origin.
Genome biology and evolution5(8)1485-502(2013)
Feiner N,Murakami Y,Breithut L,Mazan S,Meyer A,Kuraku S

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klhl40a cDNA ORF clone, Danio rerio(zebrafish)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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