pmm2 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	pmm2
Entrez Gene ID	368229
Full Name	phosphomannomutase 2
Synonyms	cb626,zgc:56149
General protein information	Preferred Names phosphomannomutase 2 Names phosphomannomutase 2
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_200084.1	NP_956378.1	phosphomannomutase 2

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	PMM2	XP_001102327.1
Bos taurus (cattle)	PMM2	NP_001030267.1
Oryza sativa (rice)	Os04g0682300	NP_001054295.1
Kluyveromyces lactis	KLLA0D05709g	XP_453316.1
Eremothecium gossypii	AGOS_ABR236W	NP_983185.1
Schizosaccharomyces pombe (fission yeast)	pmm1	NP_594325.1
Homo sapiens (human)	PMM2	NP_000294.1
Pan troglodytes (chimpanzee)	PMM2	XP_510805.3
Rattus norvegicus (Norway rat)	Pmm2	NP_001100443.1
Gallus gallus (chicken)	PMM2	NP_001026639.1
Arabidopsis thaliana (thale cress)	PMM	NP_182103.1
Caenorhabditis elegans (roundworm)	CELE_F52B11.2	NP_001255786.1
Saccharomyces cerevisiae (baker's yeast)	SEC53	NP_116609.1
Xenopus tropicalis (tropical clawed frog)	pmm1	NP_001106421.1
Magnaporthe oryzae (rice blast fungus)	MGG_01637	XP_003714625.1
Canis lupus familiaris (dog)	PMM2	XP_547133.3
Mus musculus (house mouse)	Pmm2	NP_058577.1
Danio rerio (zebrafish)	pmm2	NP_956378.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011353	XP_309297.2
Drosophila melanogaster (fruit fly)	CG10688	NP_648589.1
Neurospora crassa	NCU02829	XP_963786.1

Gene Ontology
Bibliography

Related articles in PubMed

Nrf2 activation attenuates genetic endoplasmic reticulum stress induced by a mutation in the phosphomannomutase 2 gene in zebrafish.
Mukaigasa K, Tsujita T, Nguyen VT, Li L, Yagi H, Fuse Y, Nakajima-Takagi Y, Kato K, Yamamoto M, Kobayashi M
Proceedings of the National Academy of Sciences of the United States of America115(11)2758-2763(2018 03)

trappc11 is required for protein glycosylation in zebrafish and humans.
DeRossi C, Vacaru A, Rafiq R, Cinaroglu A, Imrie D, Nayar S, Baryshnikova A, Milev MP, Stanga D, Kadakia D, Gao N, Chu J, Freeze HH, Lehrman MA, Sacher M, Sadler KC
Molecular biology of the cell27(8)1220-34(2016 Apr)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes.
Briolat V, Jouneau L, Carvalho R, Palha N, Langevin C, Herbomel P, Schwartz O, Spaink HP, Levraud JP, Boudinot P
Journal of immunology (Baltimore, Md. : 1950)192(9)4328-41(2014 May)

Evolution of the miR199-214 cluster and vertebrate skeletal development.
Desvignes T, Contreras A, Postlethwait JH
RNA biology11(4)281-94(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following pmm2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the pmm2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa33596	NM_200084.1 Latest version!	Danio rerio phosphomannomutase 2 (pmm2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

pmm2 ( NM_200084.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_956378.1 Danio rerio phosphomannomutase 2 (pmm2), mRNA.

Price & Availability↑

CloneID	ODa33596
Clone ID Related Accession (Same CDS sequence)	NM_200084.1
Accession Version	NM_200084.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 753bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1554480000000
Organism	Danio rerio(zebrafish)
Product	phosphomannomutase 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC051778.1. ##Evidence-Data-START## Transcript exon combination :: BC051778.1, EH542870.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGTCTGGCT CTACCGTGGA TTCGACAACG CTGTGTCTGT TTGACGTGGA CGGGACTTTA 
ACAGCAGCTC GTCAAAAAGC CACCGCAGAC ATGCATGAGT TTCTGTCTAA ACTGAAACAG 
CGTGTGAAAG TCGGAGTGGT TGGAGGATCA GATCTGGACA AAATCAAAGA GCAGCTTGGA 
GATGATGTGA TTGACAGAGT GGATTACGTG TTTGCTGAGA ACGGTTTGGT TGCGTACAGG 
TTTGGAAAGC TTCACTCTGT GCAGAATATT CAGGCCTACC TGGGAGAAGA CATTTTGCAG 
GAATTCATCA ATTTCTGCCT CAATTACCTT TCAAAGATTA AACTGCCTAA AAAAAGAGGC 
ACATTTATTG AATTTCGGAA TGGAATGCTG AATGTCTCTC CGATCGGTCG AAGCTGCAGC 
CAACAGGAAA GAATCGAATT CTTTGAACTT GATAAGAAGG AGAAGATTAG AGAAACATTT 
GTCTCCGTTT TAAAAGAAGA GTTTGCTGGG AAGGGACTAG CTTTCTCCAT TGGTGGACAG 
ATCAGTTTTG ATGTGTTTCC AGAAGGCTGG GATAAGCGCT ACTGTTTGGG AATTGTGGAG 
AAAGACTCCT ATCAGCACAT CCATTTCTTT GGAGACAAAA CAATGCCTGG AGGAAATGAC 
TACGAAATCT TTGTAGACCC CAGAACAATC GGCCATGAGG TCAAATCTCC TGAAGACACA 
CAGAGGATCT GCAGGGAGCT CTTTTTCAGC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_956378.1
CDS	294..1046
Translation	MSGSTVDSTTLCLFDVDGTLTAARQKATADMHEFLSKLKQRVKVGVVGGSDLDKIKEQLGDDVIDRVDYVFAENGLVAYRFGKLHSVQNIQAYLGEDILQEFINFCLNYLSKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQQERIEFFELDKKEKIRETFVSVLKEEFAGKGLAFSIGGQISFDVFPEGWDKRYCLGIVEKDSYQHIHFFGDKTMPGGNDYEIFVDPRTIGHEVKSPEDTQRICRELFFS

Target ORF information:

RefSeq Version	NM_200084.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio phosphomannomutase 2 (pmm2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_200084.1

ORF Insert Sequence:

ATGTCTGGCT CTACCGTGGA TTCGACAACG CTGTGTCTGT TTGACGTGGA CGGGACTTTA 
ACAGCAGCTC GTCAAAAAGC CACCGCAGAC ATGCATGAGT TTCTGTCTAA ACTGAAACAG 
CGTGTGAAAG TCGGAGTGGT TGGAGGATCA GATCTGGACA AAATCAAAGA GCAGCTTGGA 
GATGATGTGA TTGACAGAGT GGATTACGTG TTTGCTGAGA ACGGTTTGGT TGCGTACAGG 
TTTGGAAAGC TTCACTCTGT GCAGAATATT CAGGCCTACC TGGGAGAAGA CATTTTGCAG 
GAATTCATCA ATTTCTGCCT CAATTACCTT TCAAAGATTA AACTGCCTAA AAAAAGAGGC 
ACATTTATTG AATTTCGGAA TGGAATGCTG AATGTCTCTC CGATCGGTCG AAGCTGCAGC 
CAACAGGAAA GAATCGAATT CTTTGAACTT GATAAGAAGG AGAAGATTAG AGAAACATTT 
GTCTCCGTTT TAAAAGAAGA GTTTGCTGGG AAGGGACTAG CTTTCTCCAT TGGTGGACAG 
ATCAGTTTTG ATGTGTTTCC AGAAGGCTGG GATAAGCGCT ACTGTTTGGG AATTGTGGAG 
AAAGACTCCT ATCAGCACAT CCATTTCTTT GGAGACAAAA CAATGCCTGG AGGAAATGAC 
TACGAAATCT TTGTAGACCC CAGAACAATC GGCCATGAGG TCAAATCTCC TGAAGACACA 
CAGAGGATCT GCAGGGAGCT CTTTTTCAGC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Nrf2 activation attenuates genetic endoplasmic reticulum stress induced by a mutation in the phosphomannomutase 2 gene in zebrafish.
Proceedings of the National Academy of Sciences of the United States of America115(11)2758-2763(2018 03)
Mukaigasa K,Tsujita T,Nguyen VT,Li L,Yagi H,Fuse Y,Nakajima-Takagi Y,Kato K,Yamamoto M,Kobayashi M

trappc11 is required for protein glycosylation in zebrafish and humans.
Molecular biology of the cell27(8)1220-34(2016 Apr)
DeRossi C,Vacaru A,Rafiq R,Cinaroglu A,Imrie D,Nayar S,Baryshnikova A,Milev MP,Stanga D,Kadakia D,Gao N,Chu J,Freeze HH,Lehrman MA,Sacher M,Sadler KC

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes.
Journal of immunology (Baltimore, Md. : 1950)192(9)4328-41(2014 May)
Briolat V,Jouneau L,Carvalho R,Palha N,Langevin C,Herbomel P,Schwartz O,Spaink HP,Levraud JP,Boudinot P

Evolution of the miR199-214 cluster and vertebrate skeletal development.
RNA biology11(4)281-94(2014)
Desvignes T,Contreras A,Postlethwait JH

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

pmm2 cDNA ORF clone, Danio rerio(zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM