foxc1a cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	foxc1a
Entrez Gene ID	100148408
Full Name	forkhead box C1a
Synonyms	foxc1.1
General protein information	Preferred Names forkhead box C1a Names forkhead box C1-A
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_131728.3	NP_571803.1	forkhead box C1-A

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Foxc1	NP_032618.2
Danio rerio (zebrafish)	foxc1a	NP_571803.1
Pan troglodytes (chimpanzee)	FOXC1	XP_003311061.2
Xenopus tropicalis (tropical clawed frog)	foxc1	NP_001007864.1
Homo sapiens (human)	FOXC1	NP_001444.2
Rattus norvegicus (Norway rat)	Foxc1	NP_599165.1

Gene Ontology
Bibliography

Related articles in PubMed

foxc1 is required for embryonic head vascular smooth muscle differentiation in zebrafish.
Whitesell TR, Chrystal PW, Ryu JR, Munsie N, Grosse A, French CR, Workentine ML, Li R, Zhu LJ, Waskiewicz A, Lehmann OJ, Lawson ND, Childs SJ
Developmental biology453(1)34-47(2019 Sep)

Loss of foxc1 in zebrafish reduces optic nerve size and cell number in the retinal ganglion cell layer.
Umali J, Hawkey-Noble A, French CR
Vision research15666-72(2019 03)

Gene profiling of head mesoderm in early zebrafish development: insights into the evolution of cranial mesoderm.
Wang H, Holland PWH, Takahashi T
EvoDevo1014(2019)

Identification of Dmrt2a downstream genes during zebrafish early development using a timely controlled approach.
Pinto RA, Almeida-Santos J, Lourenço R, Saúde L
BMC developmental biology18(1)14(2018 06)

Fox proteins are modular competency factors for facial cartilage and tooth specification.
Xu P, Balczerski B, Ciozda A, Louie K, Oralova V, Huysseune A, Crump JG
Development (Cambridge, England)145(12)(2018 06)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following foxc1a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the foxc1a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa00924	NM_131728.3 Latest version!	Danio rerio forkhead box C1a (foxc1a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

foxc1a ( NM_131728.3 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_571803.1 Danio rerio forkhead box C1a (foxc1a), mRNA.

Price & Availability↑

CloneID	ODa00924
Clone ID Related Accession (Same CDS sequence)	NM_131728.3
Accession Version	NM_131728.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1578067200000
Organism	Danio rerio(zebrafish)
Product	forkhead box C1-A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from FP149176.1, FP141849.1, CD281289.1 and CT690954.2. On Apr 4, 2014 this sequence version replaced NM_131728.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BC053129.1 [ECO:0000345] ##Evidence-Data-END##

ATGCAGGCGC GCTATTCCGT CTCCAGTCCC AACTCGCTGG GAGTTGTGCC GTACATCAGC 
AGCGACCAAA GTTATTACCG AGCCGCCGCC GGAGGGGGGT ACACCGGCAT GCCAGCCCCC 
ATGACCATGT ACTCTCACGC GGCCCACGAC CAGTACCCCG CCAGCATGGC GAGGGCATAT 
GGGCCATACA CTCCACAGCC GCAGCCTAAG GATATGGTGA AACCCCCGTA CAGCTACATT 
GCGCTCATCA CAATGGCAAT CCAGAACTCC CCGGACAAAA AGGTGACCCT TAATGGTATT 
TATCAGTTCA TCATGGAGCG CTTTCCCTTT TACAGAGACA ACAAGCAGGG CTGGCAGAAC 
AGCATCCGGC ATAATTTATC CCTGAACGAG TGCTTTGTCA AAGTTCCACG CGATGATAAG 
AAACCCGGAA AAGGCAGCTA CTGGACCCTC GACCCGGACT CGTATAATAT GTTTGAGAAC 
GGCAGCTTTT TGAGGCGACG ACGGCGATTT AAAAAGAAGG ACGCCATGAA GGACAAGGAG 
GACCGAGGTG TTAAAGAGGC GCCGTCCCGC CAGGCGCAGC CGCAGGCCCG CGAGCAGGAG 
CAGTCGGTGC CTGGCTCTCA GCCCGTGCGC ATTCAGGACA TTAAAACCGA GAACGGCACG 
TCCACTCCTC CGCAGGCTGT TTCGCCCACG CTAAGCACCG TCCCGAAGAT CGAGAGCCCC 
GACAGCAGCA GCAGCATGTC GAGCGGCAGC CCGCACAGCA TCCCTTCCAC CCGCTCCCTC 
AGCCTGGACA GCGCTGGAGA GCAGCACCAC CAGGCCCCCG CGCAGGGCTT CAGCGTGGAC 
AACATCATGA CCTCCCTCCG CGGATCGCCG CACAGCTCCG GAGAGCTCAC CCCGTCTCTC 
GTGGCTCCCT CGCGGACAGG TATAACACCC ACGTTGTCCC TGAATTATTC TCCCAATCAG 
TCGTCCGTGT ACAGCTCGCC CTGCAGCCAG AACTCTATCT CGACTACCTC CAACGCCACC 
TATCACTGCA ACATGCAGGC CATGAGCTTG TACGCGGGCG GAGATCGCTC GGGCCACTTG 
GGGACCACCG CTACCACCGT GGACGAAACT CTGCCTGATT ACTCGATCAC GACCACCACG 
TCGTCGTTGA GCCACGGGAA TCTGAGCTCG GCCCAGGAGG GCCACCATCC GCACCAAGGG 
CGCCTCGCCT CATGGTACCT GAACCAGGCC GGAGACATTG GCCATCTAGG CGCGACGTAC 
CCAGCGCAGC AGCAGAACTT CCATTCGGTT CGAGAGATGT TCGAATCGCA GAGAATCGGT 
CTGAATAATT CGCCGGTAAA CGGGAATAAC AGCTGTCAAA TGTCGTTTCC CCCGAGCCAG 
CCCATTTACC GCACGTCGGG GGCTTTTGTG TATGACTGCA GCAAATTTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_571803.1
CDS	258..1688
Translation	MQARYSVSSPNSLGVVPYISSDQSYYRAAAGGGYTGMPAPMTMYSHAAHDQYPASMARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNSPDKKVTLNGIYQFIMERFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAMKDKEDRGVKEAPSRQAQPQAREQEQSVPGSQPVRIQDIKTENGTSTPPQAVSPTLSTVPKIESPDSSSSMSSGSPHSIPSTRSLSLDSAGEQHHQAPAQGFSVDNIMTSLRGSPHSSGELTPSLVAPSRTGITPTLSLNYSPNQSSVYSSPCSQNSISTTSNATYHCNMQAMSLYAGGDRSGHLGTTATTVDETLPDYSITTTTSSLSHGNLSSAQEGHHPHQGRLASWYLNQAGDIGHLGATYPAQQQNFHSVREMFESQRIGLNNSPVNGNNSCQMSFPPSQPIYRTSGAFVYDCSKF

Target ORF information:

RefSeq Version	NM_131728.3
Organism	Danio rerio(zebrafish)
Definition	Danio rerio forkhead box C1a (foxc1a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_131728.3

ORF Insert Sequence:

ATGCAGGCGC GCTATTCCGT CTCCAGTCCC AACTCGCTGG GAGTTGTGCC GTACATCAGC 
AGCGACCAAA GTTATTACCG AGCCGCCGCC GGAGGGGGGT ACACCGGCAT GCCAGCCCCC 
ATGACCATGT ACTCTCACGC GGCCCACGAC CAGTACCCCG CCAGCATGGC GAGGGCATAT 
GGGCCATACA CTCCACAGCC GCAGCCTAAG GATATGGTGA AACCCCCGTA CAGCTACATT 
GCGCTCATCA CAATGGCAAT CCAGAACTCC CCGGACAAAA AGGTGACCCT TAATGGTATT 
TATCAGTTCA TCATGGAGCG CTTTCCCTTT TACAGAGACA ACAAGCAGGG CTGGCAGAAC 
AGCATCCGGC ATAATTTATC CCTGAACGAG TGCTTTGTCA AAGTTCCACG CGATGATAAG 
AAACCCGGAA AAGGCAGCTA CTGGACCCTC GACCCGGACT CGTATAATAT GTTTGAGAAC 
GGCAGCTTTT TGAGGCGACG ACGGCGATTT AAAAAGAAGG ACGCCATGAA GGACAAGGAG 
GACCGAGGTG TTAAAGAGGC GCCGTCCCGC CAGGCGCAGC CGCAGGCCCG CGAGCAGGAG 
CAGTCGGTGC CTGGCTCTCA GCCCGTGCGC ATTCAGGACA TTAAAACCGA GAACGGCACG 
TCCACTCCTC CGCAGGCTGT TTCGCCCACG CTAAGCACCG TCCCGAAGAT CGAGAGCCCC 
GACAGCAGCA GCAGCATGTC GAGCGGCAGC CCGCACAGCA TCCCTTCCAC CCGCTCCCTC 
AGCCTGGACA GCGCTGGAGA GCAGCACCAC CAGGCCCCCG CGCAGGGCTT CAGCGTGGAC 
AACATCATGA CCTCCCTCCG CGGATCGCCG CACAGCTCCG GAGAGCTCAC CCCGTCTCTC 
GTGGCTCCCT CGCGGACAGG TATAACACCC ACGTTGTCCC TGAATTATTC TCCCAATCAG 
TCGTCCGTGT ACAGCTCGCC CTGCAGCCAG AACTCTATCT CGACTACCTC CAACGCCACC 
TATCACTGCA ACATGCAGGC CATGAGCTTG TACGCGGGCG GAGATCGCTC GGGCCACTTG 
GGGACCACCG CTACCACCGT GGACGAAACT CTGCCTGATT ACTCGATCAC GACCACCACG 
TCGTCGTTGA GCCACGGGAA TCTGAGCTCG GCCCAGGAGG GCCACCATCC GCACCAAGGG 
CGCCTCGCCT CATGGTACCT GAACCAGGCC GGAGACATTG GCCATCTAGG CGCGACGTAC 
CCAGCGCAGC AGCAGAACTT CCATTCGGTT CGAGAGATGT TCGAATCGCA GAGAATCGGT 
CTGAATAATT CGCCGGTAAA CGGGAATAAC AGCTGTCAAA TGTCGTTTCC CCCGAGCCAG 
CCCATTTACC GCACGTCGGG GGCTTTTGTG TATGACTGCA GCAAATTTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

foxc1 is required for embryonic head vascular smooth muscle differentiation in zebrafish.
Developmental biology453(1)34-47(2019 Sep)
Whitesell TR,Chrystal PW,Ryu JR,Munsie N,Grosse A,French CR,Workentine ML,Li R,Zhu LJ,Waskiewicz A,Lehmann OJ,Lawson ND,Childs SJ

Loss of foxc1 in zebrafish reduces optic nerve size and cell number in the retinal ganglion cell layer.
Vision research15666-72(2019 03)
Umali J,Hawkey-Noble A,French CR

Gene profiling of head mesoderm in early zebrafish development: insights into the evolution of cranial mesoderm.
EvoDevo1014(2019)
Wang H,Holland PWH,Takahashi T

Identification of Dmrt2a downstream genes during zebrafish early development using a timely controlled approach.
BMC developmental biology18(1)14(2018 06)
Pinto RA,Almeida-Santos J,Lourenço R,Saúde L

Fox proteins are modular competency factors for facial cartilage and tooth specification.
Development (Cambridge, England)145(12)(2018 06)
Xu P,Balczerski B,Ciozda A,Louie K,Oralova V,Huysseune A,Crump JG