putative ABCA3 cDNA ORF clone, Leishmania infantum JPCM5

Gene
Clones
gRNAs

Summary

Gene Symbol	putative ABCA3
Entrez Gene ID	5067301
Full Name	ATP-binding cassette protein subfamily A, member 3
Gene Type	protein-coding
Organism	Leishmania infantum JPCM5

mRNA and Protein(s)

mRNA	Protein	Name
XM_001463885.1	XP_001463922.1	ATP-binding cassette protein subfamily A, member 3

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania.
Rogers MB, Hilley JD, Dickens NJ, Wilkes J, Bates PA, Depledge DP, Harris D, Her Y, Herzyk P, Imamura H, Otto TD, Sanders M, Seeger K, Dujardin JC, Berriman M, Smith DF, Hertz-Fowler C, Mottram JC
Genome research21(12)2129-42(2011 Dec)

Comparative genomic analysis of three Leishmania species that cause diverse human disease.
Peacock CS, Seeger K, Harris D, Murphy L, Ruiz JC, Quail MA, Peters N, Adlem E, Tivey A, Aslett M, Kerhornou A, Ivens A, Fraser A, Rajandream MA, Carver T, Norbertczak H, Chillingworth T, Hance Z, Jagels K, Moule S, Ormond D, Rutter S, Squares R, Whitehead S, Rabbinowitsch E, Arrowsmith C, White B, Thurston S, Bringaud F, Baldauf SL, Faulconbridge A, Jeffares D, Depledge DP, Oyola SO, Hilley JD, Brito LO, Tosi LR, Barrell B, Cruz AK, Mottram JC, Smith DF, Berriman M
Nature genetics39(7)839-47(2007 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following putative ABCA3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the putative ABCA3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OLc01197	XM_001463885.1 Latest version!	Leishmania infantum JPCM5 ATP-binding cassette protein subfamily A, member 3 (putative ABCA3), partial mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$951.30 $1359.00

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Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

putative ABCA3 ( XM_001463885.1 ) cDNA ORF clone, Leishmania infantum JPCM5 -> XP_001463922.1 Leishmania infantum JPCM5 ATP-binding cassette protein subfamily A, member 3 (putative ABCA3), partial mRNA.

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CloneID	OLc01197
Clone ID Related Accession (Same CDS sequence)	XM_001463885.1
Accession Version	XM_001463885.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5418bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1436889600000
Organism	Leishmania infantum JPCM5
Product	ATP-binding cassette protein subfamily A, member 3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_009395). COMPLETENESS: incomplete on both ends.

ATGGAGCCGG TGACCACCGC CGTGCACCCG CTTGGCGGCA CCGAGGCGTC TAATCGTAGC 
TGGTACTCAC CCTCGAAGCG GCGCGCCGGC TTGGGCGCGA TGCGTCGCAA CGAGCTGATG 
AGCCGAACTG TGAACCTTAG CAGATTAGAC ATGCATATGT CTAGTAATCT CTCATTGGGG 
GCCAGTAGGA CGAGCACTGT GTCAGAGAAG GACACCTCCA CGAACAGCGG CGGTAAGGGG 
TCCCCAGATG ACAGCGACAG CTTCAGTGAT ACCGATGAGG TGCCCGCGCG CGCCTCTTTC 
GTGGACCAGC TGCTCGCTGT AGTAGAACGC TCGACGCGAG AGCTCTGGCG GCGTAAGTTG 
GACCTGCTTT TAGACATCAC CGTGCCACTG ATCTTCGTGG TCGTGTCCAT TGCGTTGTGG 
GCCATCTGGG GCACGCAGTA CAACGAGGAG ATGACTTACG TTTCCACGAA TCTGGAGTCT 
GGCAACATCG GTGCGGCCGG TCTTCGTGCA CCGGCTACCT ACGACTTCAC GTGCATGAGG 
CAGCCAGAAG GGACGCCAAC GTTGGCTGAC TTCACACGCT GCAAGCCCAT GGACTACACC 
ACCTGCGATT CTGTCACGGG GGAGTGCAAG ACGCAGAGCA TCATCACCTT CATCTGCGAT 
GGCGACTCGA GCATGCTTCC GCTGCCGGAG GAATACGAGA TATGCCGTGT ATCGTACGAC 
TGGGAGGAGC TCATCACTGC AGGTTTAAGC TACTACTGGC GATGGCTGTC AGCTGTCCCC 
ACCCTCGACA TGCTCATAGG TCTCCAGTGG ACGGCTCTGT CTGCGTACCG CTATCTACTC 
CCTTTCATCG CGAAAACGAT GGCCGGGCTC GCCGCCAACA CACGCTACAG TGCGATTCTG 
TGCAGCGGCC ATTTGTACTT CGTAGGTGAG CGTGGCGTGA CCTCGGAGCT AATTGCGTAC 
ATGAACAGGA CCTCTGGGCT ATTTCAATAC GTGACGGACT TTCAGGTGTA CAGCAGCGTC 
GCGGAGGCTC GCAGCGCTGC GAGGCGCGGT GGCCGTGTAT GGGCGATCGT GGAGCTGCGG 
CAGATCGGCG AGGCGGGGCT GGATCTTGTG CTGCATATGA ACAACTCCGC CCTGCCGTCG 
TTTGCCACCA CGTACGACGA CGCGTACAGC GGCGGGGTGC TGTTTGACAC GGCGGAGCTG 
TACATGCTAT CCGGCTTCAA CACGCTACAG CAGCTGGTGT CGGAGTTCTA CCTGAACACA 
TTCCACGACG CGCAGATGAA CATGACGCAG ATGATGGCGG CCACGGCCAC TCCAGAGTAC 
AAGCGCGTGC CGCTGATGGC GCAGGCGCGA CAGGTACTAC CGCTCATCTT CTCCCTTGCC 
TTTCTGTACA GCGTGTCGCA GCAGACGAAG CGCATCGTGC TGGAGAAGGA GCTGCGGATC 
CGCGAGGCCA TGCAGATCAT GGGGCTGAAG CAGTGGACGC TCTACGCGAG CGAGCTCATT 
GTGCAGATGG CGATATTTGT GCCGACGTGC GTGCTGTGCG TGGTGATGCT GAAGCTGACG 
TACGTGACGA AGAGCGACCC GCTGATTCTG TTCCTCATCT TCTGCCTCTT CGCCCTCACG 
ACGATCCCGC TGTCCGGCAT GATCGCTGCT TTCTTCAGCA AGTCGCGCCT GGCGTCGCTG 
GTAGCGCCGG TGGTGTACTT TATCCTTGTG ATCCCGATGT TCGCCATGAC CAACGCGCAG 
GGCTTGATCG TGACGTGGTT CTCTGTGTTC TCGCCGACGG GGTTTGCTGC GGCGCTGAAT 
GTGTTCCTAC TGCACGAGTC TGGGAGCGGG TGCGGCGCGG CGGAGATGAT GTCGAGTCGC 
GACAACCCGA CGCTGGCAGT TGTGCTTGTG ATGCTGGCGG TGGACTGCTG CATGTACTAC 
GCGCTGATGC TGTACCTGGA CGCGGTCCTG CCGAAGCAGT GGGGTACGCC CAAGCACCCG 
CTCTTCTTCA TCATGGAGCC GGTGCGGTGG TTTTCTGGAC CGAGCGCGCG CGTGCTGGAG 
GGCGGCGCCG ACGGGCGCGC CGAGAACGGC GTGTTCGAGG AGATCACAGA AGGCGGCGCC 
GACTACGCCG TTTGCGCCAC TGGGCTGCGC AAGGAGTACT CGCGCGGCGG CAAGAGGTTC 
GTTGCGGTGA ACAACCTGTA CTGGGGGATG CGCGAGGGCG AGATCTCTGT GCTGCTGGGG 
CACAACGGCG CCGGCAAGAC GACGGTGCTG AACATGATGA CGGGGATGGT ATCGGCGGAC 
GCGGGCGACT GCTACATTTA CGGCAGCTCT GTCCGCAACC AGCTAGAGAA GGCGCGCCAG 
CAGATCGGAT ACTGCCCGCA GCACAACATC CTATGGGGCG AGCTGACGTG CCGCGACCAC 
CTGGAGTTCT TTGGGCGTAT TAAGGGGTTG CGCGGGTGGG AGCTGGAGAA TGCCGTGTGC 
CGGATGCTGC ACGAGACGGA CCTGCTGGAG AAGATGGACC AGCCGGCGAA GAGCCTGTCT 
GGCGGGCAGA AGCGCAAGCT GTCGATCGCG GTCGCGTTTG TTGGCGGCAG CCGTCTTGTG 
TTTCTCGACG AGCCGACTGC CGGGCTGGAC GTTGGCGCGC GGCGGCAGAC GTGGGAGCTG 
CTGCGGCGCA TGTCGCATTC ATGCACGCTG CTGCTGACGA CGCACTTCAT GGACGAGGCG 
GACCTGCTGG GACAGCGAAT CGGGATCATG AGCCAGGGGC GACTGAAGTG CTCGGGCAGC 
AGCCTTTTCC TGAAGTCGCG GCTGGGTGTC GGCTACAACA TCGTCATTTC CGTTGATCCC 
GAGCTAGATC TCGATGCTGT GGATGAAGTG GTGCTTGGAA CGGTGGATGG CGCGGAGCTG 
CTTGGGCGGA ACGGGTGTGA GGTATCGTAC CAGCTACCTG TGCAGAGCGT GAGCCAGTTC 
CCGGCGCTGC TGAACGAGAT AGACTCCGTG GAGGCGGACG GCATCCGCGG CTACTCGCTG 
GCTGCGACGA CGCTGGAGGA GGTGTTCTTG AAGGTTTCGG AGGAGGACAT CTCGGGCCGT 
AGCGAGGCTG CAGCGCAGGA GGGCGTGGAG CTAATCTGGA ACTGCGAGGT GGCGCCGTCA 
GCGCTATGGC TGCAGTTCCG TGCGATGATC GCGAAGCGGT TCTGGAGCGC GCTGCGGGAC 
CGGAAGATGC AGTGCTTCCA GATTGTGTGC CCGGTTGTGT GCATCCTGAT CGCCATGCTG 
CTGAACCTCG TGCGGTACCG AGACCCTCAG TCGCTTACGT ACAACTACTC GATGTTCGCG 
AACCGACCGA CTTCTGTGCT GGACACATCG TTCTGCGACG CGATGTGGGG TGGCGCTCCG 
ACGGGCGCGG TGGACTACGA GGTGAACGAG ACTCACTTGA CGGGTGCGCA GGCGCTGTCG 
GACTACCTGC TGGATACGTG GTACGTGCAC GACATGCCGC GCTACGGCGC TGTGTCGTGC 
ATTGATCGGA ACGTGACGGC GCTGCTGAGA TTTGCGGATG AGTGGCGCGG CACCAACGTG 
AACGTGTTCC TGTACAACTC CTCCTCGCAC CATCAGGCTG GGCTGAACCT CGCAACGTAC 
TACGACCTGT TCATCAAGTC CTTCCTCGGC CGCGACAGCG CGTTCATGCG GTACAAGGTG 
GAGCTGTTCA ACGAGCCTGC GAGCCAGTCG CAGCTGGGCT TCATCTTCAT TGGCGCCCTG 
GTGATGATCC CGTTCACGTT CCTGCCGGCG AACCCTGTTG CGTGGGTGGT GAAGGAGCGG 
CAGTGCGGGT CGCGGCACCT GCAGGACCTG TGCGGGCTGA GCTTCTTCGT GTACTGGACG 
GCCAACTATA CATTCGACAT GCTGGCCTAC TTTGTCACGA CGCTGCTGTG CATCCTCATC 
TTCTGTATCT TCAGCCGGCA GGATTTCGTC GGGCCGGACC GTGCTGGCGG CACGTTTATG 
CTGCTCATGG TCTACGGGCT CACGAGCACC GCTGGCGCGT ACGCGCTGAG CTTCCTGTTC 
AAGGAGCACT CGTCTGCGCA GACGATCGTG ATGGGTGTCG GCTTTGTTGC CGGGTTCCTT 
CTGTTGATGC TGGTGTACGT GCTGGCGCTG GATCCAGGCA ACGTGGACAC GTCAGACAAG 
ATGCGGTGGG AATTCCGGTT GATCCCGTCG TACTGCATCG GCGAGGGGCT CATCGGGCTG 
CTGATGCTGG ACAGCAAGCT GGCCATGGGC ACCGCAACCA GTGCTTGGGA CATGGACCAG 
CTTGGGTGGC CGCTGCTGTA CATGGCAGTG GAGCTCCCTG CGTTCTGGCT GATCGTTCTG 
TGCGTGGACC ACCCGGCGGT GAGGCGGTGC CTGCAGCGGC TGCGCTACAA CCGCGACGCG 
GAGCCAATCA TCCCGAGCGA CGAGGACTCG GACGTGGAGG ACGAGCGCGA GGCTGTGTAC 
GAGGCGGGGC AGATGGGCGA CACGACGAGC GACGTTGTGC GAGTGGTGAA CCTGCAGAAG 
CGGTACGGGA ACGGTAACAT TGCTGTGAAG GGCATCACGT TCTCGATCTT CCCCGGGGAG 
GTGTTCGGCT TTCTCGGCAC GAACGGTGCT GGCAAGACGA CGACGATTTC GATGCTGTGC 
CAGCAGTTCC TGCCGACGGG CGGCAGCGCG TACGTGTGCG GGTACGACAT CGTTGAGCAG 
AGCAAGGAGG CGCTGCAGTG CATCGGGTAC TGCCCGCAGT TCGACGCGAC GCTGGACCTG 
CTCACTGTGG AGGAGCAGCT GGAGCTGTAC GCTGGGATCC GCGGGATCGT GCGTGCGGAG 
TGGCCTGCGC TCGTGGACGC GCTGTGCACG CTGTGCGAGC TAACGATGTA CCGCAAGACG 
GTGACGAGTG CGCTCTCCGG TGGCAACCGG CGCAAGCTGT CTGTGGCGAT AGCGCTGGTG 
GGCGGTCCGC AGGTGGTCTT CCTGGACGAG CCGTCGGCCG GCATGGACCC TGTGGCGCGA 
CGCGGGATGT GGACTGCGAT CCAGCGCGCC GCGGGGCACT GCTCCGTTGT GCTGACGACG 
CACCACCTGG AGGAGGTGGA GGCGCTCGCG GACATTGTGG CGATCATGGT GCGCGGGTAC 
GTGCGGTGCG TCGGCGACAA GGTGCACCTG AAGAACAAGT TCGGCAGCGC CTTCGAGGTG 
AGCGTGCGGC TCGCGTCGGC GCAGCACGCG GAGCTCTTTG CGTCGTTCAT GCAGGCGGCG 
TTCCCCGACG CTGTGCGGAG CGAAGGCGAG GGTCGGCGGC TCGTGTACCA GCTGCCGCGC 
GATCGCGGCT TCGGCGACGT GTTCCAGACG TTCCAGGCGA ACAAGGAGCA GCTGCACATC 
ACGGACTACA GCGTGTCGCA GACGTCCATT GAACAGATCT TTATGAAGGT TCGGGCACTT 
GCGATGAATT TACGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_001463922.1
CDS	1..5418
Translation	MEPVTTAVHPLGGTEASNRSWYSPSKRRAGLGAMRRNELMSRTVNLSRLDMHMSSNLSLGASRTSTVSEKDTSTNSGGKGSPDDSDSFSDTDEVPARASFVDQLLAVVERSTRELWRRKLDLLLDITVPLIFVVVSIALWAIWGTQYNEEMTYVSTNLESGNIGAAGLRAPATYDFTCMRQPEGTPTLADFTRCKPMDYTTCDSVTGECKTQSIITFICDGDSSMLPLPEEYEICRVSYDWEELITAGLSYYWRWLSAVPTLDMLIGLQWTALSAYRYLLPFIAKTMAGLAANTRYSAILCSGHLYFVGERGVTSELIAYMNRTSGLFQYVTDFQVYSSVAEARSAARRGGRVWAIVELRQIGEAGLDLVLHMNNSALPSFATTYDDAYSGGVLFDTAELYMLSGFNTLQQLVSEFYLNTFHDAQMNMTQMMAATATPEYKRVPLMAQARQVLPLIFSLAFLYSVSQQTKRIVLEKELRIREAMQIMGLKQWTLYASELIVQMAIFVPTCVLCVVMLKLTYVTKSDPLILFLIFCLFALTTIPLSGMIAAFFSKSRLASLVAPVVYFILVIPMFAMTNAQGLIVTWFSVFSPTGFAAALNVFLLHESGSGCGAAEMMSSRDNPTLAVVLVMLAVDCCMYYALMLYLDAVLPKQWGTPKHPLFFIMEPVRWFSGPSARVLEGGADGRAENGVFEEITEGGADYAVCATGLRKEYSRGGKRFVAVNNLYWGMREGEISVLLGHNGAGKTTVLNMMTGMVSADAGDCYIYGSSVRNQLEKARQQIGYCPQHNILWGELTCRDHLEFFGRIKGLRGWELENAVCRMLHETDLLEKMDQPAKSLSGGQKRKLSIAVAFVGGSRLVFLDEPTAGLDVGARRQTWELLRRMSHSCTLLLTTHFMDEADLLGQRIGIMSQGRLKCSGSSLFLKSRLGVGYNIVISVDPELDLDAVDEVVLGTVDGAELLGRNGCEVSYQLPVQSVSQFPALLNEIDSVEADGIRGYSLAATTLEEVFLKVSEEDISGRSEAAAQEGVELIWNCEVAPSALWLQFRAMIAKRFWSALRDRKMQCFQIVCPVVCILIAMLLNLVRYRDPQSLTYNYSMFANRPTSVLDTSFCDAMWGGAPTGAVDYEVNETHLTGAQALSDYLLDTWYVHDMPRYGAVSCIDRNVTALLRFADEWRGTNVNVFLYNSSSHHQAGLNLATYYDLFIKSFLGRDSAFMRYKVELFNEPASQSQLGFIFIGALVMIPFTFLPANPVAWVVKERQCGSRHLQDLCGLSFFVYWTANYTFDMLAYFVTTLLCILIFCIFSRQDFVGPDRAGGTFMLLMVYGLTSTAGAYALSFLFKEHSSAQTIVMGVGFVAGFLLLMLVYVLALDPGNVDTSDKMRWEFRLIPSYCIGEGLIGLLMLDSKLAMGTATSAWDMDQLGWPLLYMAVELPAFWLIVLCVDHPAVRRCLQRLRYNRDAEPIIPSDEDSDVEDEREAVYEAGQMGDTTSDVVRVVNLQKRYGNGNIAVKGITFSIFPGEVFGFLGTNGAGKTTTISMLCQQFLPTGGSAYVCGYDIVEQSKEALQCIGYCPQFDATLDLLTVEEQLELYAGIRGIVRAEWPALVDALCTLCELTMYRKTVTSALSGGNRRKLSVAIALVGGPQVVFLDEPSAGMDPVARRGMWTAIQRAAGHCSVVLTTHHLEEVEALADIVAIMVRGYVRCVGDKVHLKNKFGSAFEVSVRLASAQHAELFASFMQAAFPDAVRSEGEGRRLVYQLPRDRGFGDVFQTFQANKEQLHITDYSVSQTSIEQIFMKVRALAMNLR

Target ORF information:

RefSeq Version	XM_001463885.1
Organism	Leishmania infantum JPCM5
Definition	Leishmania infantum JPCM5 ATP-binding cassette protein subfamily A, member 3 (putative ABCA3), partial mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_001463885.1

ORF Insert Sequence:

ATGGAGCCGG TGACCACCGC CGTGCACCCG CTTGGCGGCA CCGAGGCGTC TAATCGTAGC 
TGGTACTCAC CCTCGAAGCG GCGCGCCGGC TTGGGCGCGA TGCGTCGCAA CGAGCTGATG 
AGCCGAACTG TGAACCTTAG CAGATTAGAC ATGCATATGT CTAGTAATCT CTCATTGGGG 
GCCAGTAGGA CGAGCACTGT GTCAGAGAAG GACACCTCCA CGAACAGCGG CGGTAAGGGG 
TCCCCAGATG ACAGCGACAG CTTCAGTGAT ACCGATGAGG TGCCCGCGCG CGCCTCTTTC 
GTGGACCAGC TGCTCGCTGT AGTAGAACGC TCGACGCGAG AGCTCTGGCG GCGTAAGTTG 
GACCTGCTTT TAGACATCAC CGTGCCACTG ATCTTCGTGG TCGTGTCCAT TGCGTTGTGG 
GCCATCTGGG GCACGCAGTA CAACGAGGAG ATGACTTACG TTTCCACGAA TCTGGAGTCT 
GGCAACATCG GTGCGGCCGG TCTTCGTGCA CCGGCTACCT ACGACTTCAC GTGCATGAGG 
CAGCCAGAAG GGACGCCAAC GTTGGCTGAC TTCACACGCT GCAAGCCCAT GGACTACACC 
ACCTGCGATT CTGTCACGGG GGAGTGCAAG ACGCAGAGCA TCATCACCTT CATCTGCGAT 
GGCGACTCGA GCATGCTTCC GCTGCCGGAG GAATACGAGA TATGCCGTGT ATCGTACGAC 
TGGGAGGAGC TCATCACTGC AGGTTTAAGC TACTACTGGC GATGGCTGTC AGCTGTCCCC 
ACCCTCGACA TGCTCATAGG TCTCCAGTGG ACGGCTCTGT CTGCGTACCG CTATCTACTC 
CCTTTCATCG CGAAAACGAT GGCCGGGCTC GCCGCCAACA CACGCTACAG TGCGATTCTG 
TGCAGCGGCC ATTTGTACTT CGTAGGTGAG CGTGGCGTGA CCTCGGAGCT AATTGCGTAC 
ATGAACAGGA CCTCTGGGCT ATTTCAATAC GTGACGGACT TTCAGGTGTA CAGCAGCGTC 
GCGGAGGCTC GCAGCGCTGC GAGGCGCGGT GGCCGTGTAT GGGCGATCGT GGAGCTGCGG 
CAGATCGGCG AGGCGGGGCT GGATCTTGTG CTGCATATGA ACAACTCCGC CCTGCCGTCG 
TTTGCCACCA CGTACGACGA CGCGTACAGC GGCGGGGTGC TGTTTGACAC GGCGGAGCTG 
TACATGCTAT CCGGCTTCAA CACGCTACAG CAGCTGGTGT CGGAGTTCTA CCTGAACACA 
TTCCACGACG CGCAGATGAA CATGACGCAG ATGATGGCGG CCACGGCCAC TCCAGAGTAC 
AAGCGCGTGC CGCTGATGGC GCAGGCGCGA CAGGTACTAC CGCTCATCTT CTCCCTTGCC 
TTTCTGTACA GCGTGTCGCA GCAGACGAAG CGCATCGTGC TGGAGAAGGA GCTGCGGATC 
CGCGAGGCCA TGCAGATCAT GGGGCTGAAG CAGTGGACGC TCTACGCGAG CGAGCTCATT 
GTGCAGATGG CGATATTTGT GCCGACGTGC GTGCTGTGCG TGGTGATGCT GAAGCTGACG 
TACGTGACGA AGAGCGACCC GCTGATTCTG TTCCTCATCT TCTGCCTCTT CGCCCTCACG 
ACGATCCCGC TGTCCGGCAT GATCGCTGCT TTCTTCAGCA AGTCGCGCCT GGCGTCGCTG 
GTAGCGCCGG TGGTGTACTT TATCCTTGTG ATCCCGATGT TCGCCATGAC CAACGCGCAG 
GGCTTGATCG TGACGTGGTT CTCTGTGTTC TCGCCGACGG GGTTTGCTGC GGCGCTGAAT 
GTGTTCCTAC TGCACGAGTC TGGGAGCGGG TGCGGCGCGG CGGAGATGAT GTCGAGTCGC 
GACAACCCGA CGCTGGCAGT TGTGCTTGTG ATGCTGGCGG TGGACTGCTG CATGTACTAC 
GCGCTGATGC TGTACCTGGA CGCGGTCCTG CCGAAGCAGT GGGGTACGCC CAAGCACCCG 
CTCTTCTTCA TCATGGAGCC GGTGCGGTGG TTTTCTGGAC CGAGCGCGCG CGTGCTGGAG 
GGCGGCGCCG ACGGGCGCGC CGAGAACGGC GTGTTCGAGG AGATCACAGA AGGCGGCGCC 
GACTACGCCG TTTGCGCCAC TGGGCTGCGC AAGGAGTACT CGCGCGGCGG CAAGAGGTTC 
GTTGCGGTGA ACAACCTGTA CTGGGGGATG CGCGAGGGCG AGATCTCTGT GCTGCTGGGG 
CACAACGGCG CCGGCAAGAC GACGGTGCTG AACATGATGA CGGGGATGGT ATCGGCGGAC 
GCGGGCGACT GCTACATTTA CGGCAGCTCT GTCCGCAACC AGCTAGAGAA GGCGCGCCAG 
CAGATCGGAT ACTGCCCGCA GCACAACATC CTATGGGGCG AGCTGACGTG CCGCGACCAC 
CTGGAGTTCT TTGGGCGTAT TAAGGGGTTG CGCGGGTGGG AGCTGGAGAA TGCCGTGTGC 
CGGATGCTGC ACGAGACGGA CCTGCTGGAG AAGATGGACC AGCCGGCGAA GAGCCTGTCT 
GGCGGGCAGA AGCGCAAGCT GTCGATCGCG GTCGCGTTTG TTGGCGGCAG CCGTCTTGTG 
TTTCTCGACG AGCCGACTGC CGGGCTGGAC GTTGGCGCGC GGCGGCAGAC GTGGGAGCTG 
CTGCGGCGCA TGTCGCATTC ATGCACGCTG CTGCTGACGA CGCACTTCAT GGACGAGGCG 
GACCTGCTGG GACAGCGAAT CGGGATCATG AGCCAGGGGC GACTGAAGTG CTCGGGCAGC 
AGCCTTTTCC TGAAGTCGCG GCTGGGTGTC GGCTACAACA TCGTCATTTC CGTTGATCCC 
GAGCTAGATC TCGATGCTGT GGATGAAGTG GTGCTTGGAA CGGTGGATGG CGCGGAGCTG 
CTTGGGCGGA ACGGGTGTGA GGTATCGTAC CAGCTACCTG TGCAGAGCGT GAGCCAGTTC 
CCGGCGCTGC TGAACGAGAT AGACTCCGTG GAGGCGGACG GCATCCGCGG CTACTCGCTG 
GCTGCGACGA CGCTGGAGGA GGTGTTCTTG AAGGTTTCGG AGGAGGACAT CTCGGGCCGT 
AGCGAGGCTG CAGCGCAGGA GGGCGTGGAG CTAATCTGGA ACTGCGAGGT GGCGCCGTCA 
GCGCTATGGC TGCAGTTCCG TGCGATGATC GCGAAGCGGT TCTGGAGCGC GCTGCGGGAC 
CGGAAGATGC AGTGCTTCCA GATTGTGTGC CCGGTTGTGT GCATCCTGAT CGCCATGCTG 
CTGAACCTCG TGCGGTACCG AGACCCTCAG TCGCTTACGT ACAACTACTC GATGTTCGCG 
AACCGACCGA CTTCTGTGCT GGACACATCG TTCTGCGACG CGATGTGGGG TGGCGCTCCG 
ACGGGCGCGG TGGACTACGA GGTGAACGAG ACTCACTTGA CGGGTGCGCA GGCGCTGTCG 
GACTACCTGC TGGATACGTG GTACGTGCAC GACATGCCGC GCTACGGCGC TGTGTCGTGC 
ATTGATCGGA ACGTGACGGC GCTGCTGAGA TTTGCGGATG AGTGGCGCGG CACCAACGTG 
AACGTGTTCC TGTACAACTC CTCCTCGCAC CATCAGGCTG GGCTGAACCT CGCAACGTAC 
TACGACCTGT TCATCAAGTC CTTCCTCGGC CGCGACAGCG CGTTCATGCG GTACAAGGTG 
GAGCTGTTCA ACGAGCCTGC GAGCCAGTCG CAGCTGGGCT TCATCTTCAT TGGCGCCCTG 
GTGATGATCC CGTTCACGTT CCTGCCGGCG AACCCTGTTG CGTGGGTGGT GAAGGAGCGG 
CAGTGCGGGT CGCGGCACCT GCAGGACCTG TGCGGGCTGA GCTTCTTCGT GTACTGGACG 
GCCAACTATA CATTCGACAT GCTGGCCTAC TTTGTCACGA CGCTGCTGTG CATCCTCATC 
TTCTGTATCT TCAGCCGGCA GGATTTCGTC GGGCCGGACC GTGCTGGCGG CACGTTTATG 
CTGCTCATGG TCTACGGGCT CACGAGCACC GCTGGCGCGT ACGCGCTGAG CTTCCTGTTC 
AAGGAGCACT CGTCTGCGCA GACGATCGTG ATGGGTGTCG GCTTTGTTGC CGGGTTCCTT 
CTGTTGATGC TGGTGTACGT GCTGGCGCTG GATCCAGGCA ACGTGGACAC GTCAGACAAG 
ATGCGGTGGG AATTCCGGTT GATCCCGTCG TACTGCATCG GCGAGGGGCT CATCGGGCTG 
CTGATGCTGG ACAGCAAGCT GGCCATGGGC ACCGCAACCA GTGCTTGGGA CATGGACCAG 
CTTGGGTGGC CGCTGCTGTA CATGGCAGTG GAGCTCCCTG CGTTCTGGCT GATCGTTCTG 
TGCGTGGACC ACCCGGCGGT GAGGCGGTGC CTGCAGCGGC TGCGCTACAA CCGCGACGCG 
GAGCCAATCA TCCCGAGCGA CGAGGACTCG GACGTGGAGG ACGAGCGCGA GGCTGTGTAC 
GAGGCGGGGC AGATGGGCGA CACGACGAGC GACGTTGTGC GAGTGGTGAA CCTGCAGAAG 
CGGTACGGGA ACGGTAACAT TGCTGTGAAG GGCATCACGT TCTCGATCTT CCCCGGGGAG 
GTGTTCGGCT TTCTCGGCAC GAACGGTGCT GGCAAGACGA CGACGATTTC GATGCTGTGC 
CAGCAGTTCC TGCCGACGGG CGGCAGCGCG TACGTGTGCG GGTACGACAT CGTTGAGCAG 
AGCAAGGAGG CGCTGCAGTG CATCGGGTAC TGCCCGCAGT TCGACGCGAC GCTGGACCTG 
CTCACTGTGG AGGAGCAGCT GGAGCTGTAC GCTGGGATCC GCGGGATCGT GCGTGCGGAG 
TGGCCTGCGC TCGTGGACGC GCTGTGCACG CTGTGCGAGC TAACGATGTA CCGCAAGACG 
GTGACGAGTG CGCTCTCCGG TGGCAACCGG CGCAAGCTGT CTGTGGCGAT AGCGCTGGTG 
GGCGGTCCGC AGGTGGTCTT CCTGGACGAG CCGTCGGCCG GCATGGACCC TGTGGCGCGA 
CGCGGGATGT GGACTGCGAT CCAGCGCGCC GCGGGGCACT GCTCCGTTGT GCTGACGACG 
CACCACCTGG AGGAGGTGGA GGCGCTCGCG GACATTGTGG CGATCATGGT GCGCGGGTAC 
GTGCGGTGCG TCGGCGACAA GGTGCACCTG AAGAACAAGT TCGGCAGCGC CTTCGAGGTG 
AGCGTGCGGC TCGCGTCGGC GCAGCACGCG GAGCTCTTTG CGTCGTTCAT GCAGGCGGCG 
TTCCCCGACG CTGTGCGGAG CGAAGGCGAG GGTCGGCGGC TCGTGTACCA GCTGCCGCGC 
GATCGCGGCT TCGGCGACGT GTTCCAGACG TTCCAGGCGA ACAAGGAGCA GCTGCACATC 
ACGGACTACA GCGTGTCGCA GACGTCCATT GAACAGATCT TTATGAAGGT TCGGGCACTT 
GCGATGAATT TACGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania.
Genome research21(12)2129-42(2011 Dec)
Rogers MB,Hilley JD,Dickens NJ,Wilkes J,Bates PA,Depledge DP,Harris D,Her Y,Herzyk P,Imamura H,Otto TD,Sanders M,Seeger K,Dujardin JC,Berriman M,Smith DF,Hertz-Fowler C,Mottram JC

Comparative genomic analysis of three Leishmania species that cause diverse human disease.
Nature genetics39(7)839-47(2007 Jul)
Peacock CS,Seeger K,Harris D,Murphy L,Ruiz JC,Quail MA,Peters N,Adlem E,Tivey A,Aslett M,Kerhornou A,Ivens A,Fraser A,Rajandream MA,Carver T,Norbertczak H,Chillingworth T,Hance Z,Jagels K,Moule S,Ormond D,Rutter S,Squares R,Whitehead S,Rabbinowitsch E,Arrowsmith C,White B,Thurston S,Bringaud F,Baldauf SL,Faulconbridge A,Jeffares D,Depledge DP,Oyola SO,Hilley JD,Brito LO,Tosi LR,Barrell B,Cruz AK,Mottram JC,Smith DF,Berriman M

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putative ABCA3 cDNA ORF clone, Leishmania infantum JPCM5

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gRNAs

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Target ORF information:

ORF Insert Sequence:

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