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esterase

An esterase is a hydrolase enzyme that splits esters into an acid and an alcohol in a chemical reaction with water called hydrolysis.

Esterases have been a significant part of insect biochemical research over the last 50 years.

Esterases are common (biological catalysts) that play an essential role in regulating the physiological processes of organisms and contributing to disease prevention. The design and synthesis of an esterase-activated chemiluminescent probe (CL-EA) for the selective detection of esterases have been well-reported. Using the 1,2-dioxetane scaffold as the chemiluminescent platform and acetoxymethyl ether as the recognition group, the present probe was successfully lighted in the presence of esterases. As a result, a strong chemiluminescent signal was generated in an aqueous solution, thereby allowing the highly sensitive and specific detection of esterases. Furthermore, the probe is used to screen the activity of three plastic-degrading enzymes and image esterases in live cells and a mouse model. Learn more about restriction enzymes.

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