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Gene mapping

Gene mapping is the methodology used to assign a gene its location and position relative to other genes within a chromosome. There are two main gene mapping strategies, including physical and genetic linkage mapping. Physical mapping relies on molecular biology methods, such as Next-Generation Sequencing, to determine the gene location based on nucleotide sequence. Genetic linkage mapping identifies a gene’s location by evaluating unique sequences or genetic markers along the genome, such as identifiable sequences (e.g., Restriction fragment length polymorphisms, Simple sequence length polymorphisms, and Single nucleotide polymorphisms), which are generated through recombination within a chromosome or between chromosomes (cross-over).

Gene mapping is used to identify and establish the genetic bases of rare diseases, such as Angelman Syndrome and Amyotrophic Lateral Sclerosis .

Related Biology Tools

  • GenSmart™ Codon Optimization

    GenSmart Optimization is a free online tool for performing codon optimization to improve gene expression. GenScript's patented algorithms are integrated into the tool to optimize the computing capability of high-performance sequence generation.

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  • DNA Construct Design Tool

    GenSmart™ Design is a free online DNA construct design tool developed by GenScript. GenSmart™ Design has two design modules, the Create Construct module for individual plasmid design and the Create Library module for DNA library design.

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  • Codon Frequency Tables

    This online tool shows commonly used genetic codon frequency table in expression host organisms including Escherichia coli and other common host organisms.

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Service and Products

Gene Synthesis

Offer gene synthesis of 100% sequence guarantee, free codon optimization, DNA synthesis in as fast as 4 days.

ORF cDNA Clones and Custom Clones

Largest commercial ORF clones database, 70,000 next-day shipping ORF clones.

Plasmid DNA Preparation

High quality plasmids supported by fully-automated platform, 100% full insert sequence accuracy guaranteed.

Express Cloning & Subcloning

$49 and 2 day turnaround, choose from over 150 IP FREE vectors.

Mutation and Library Services

Mutagenesis Portfolio offers several mutation and library services to meet various customers’ needs.

Oligo Synthesis

Bridge the gap between chemically synthesized oligos and bological applications.

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