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The instrumentation for mass spectroscopy that allows selection of ions of a specific m/e- ratio. As the desorbed material travels down an electric field toward the detector, it passes through a space boarded by four parallel rods, which are electrodes. All four electrodes have the same DC current, onto which is superimposed an AC current that oscillates at a rate calculated to retain within the four rods only ions of the desired m/e- ratio and to deflect all other ions. Thus, the signal-to-noise ratio is kept high. By varying the charges on the electrodes, the spectrum of ions can be sampled. An alternative design is the ion-trap, in which the desorbed ions enter a cavity bounded front and back by circular entrance and exit endcap electrodes, and on the sides by a ring electrode. The voltages on all three electrodes are varied so that in-coming ions, passing through aperture in the entrance endcap electrode are directed into a circular orbit inside the ring electrode, until a sufficient number are accumulated, at which time, they are directed through an aperture in the exit endcap electrode toward the detector in a sequence that reflects their m/e- ratio.
GenSmart Optimization is a free online tool for performing codon optimization to improve gene expression. GenScript's patented algorithms are integrated into the tool to optimize the computing capability of high-performance sequence generation.
GenSmart™ Design is a free online DNA construct design tool developed by GenScript. GenSmart™ Design has two design modules, the Create Construct module for individual plasmid design and the Create Library module for DNA library design.
This online tool shows commonly used genetic codon frequency table in expression host organisms including Escherichia coli and other common host organisms.
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If you know of any terms that have been omitted from this glossary that you feel would be useful to include, please send detail to the Editorial Office at GenScript: website@genscript.com