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protease

An enzyme that cleaves peptide bonds that link Amino acids in protein molecules.enzyme or ReagentCleaves where?ExceptionsTrypsinC-terminal side of K or Rif P is C-term to K or RTrypsin (C-term to K/R, even before P)C-terminal side of K or RTrypsin (higher specificity)C-terminal side of K or Rif P is C-term to K or R; after K in CKY, DKD, CKH, CKD, KKR; after R in RRH, RRR, CRK, DRD, RRF, KRRLys C C-terminal side of KLys NN-terminal side of KCNBrC-terminal side of MArg CC-terminal side of Rif P is C-term to RAsp NN-terminal side of D Asp N / Lys CN-terminal side of D, C-terminal side of KAsp N + N-terminal Glu N-terminal side of D or EGlu C (Bicarbonate)C-terminal side of Eif P is C-term to E, or if E is C-term to EGlu C (phosphate) C-terminal side of D or Eif P is C-term to D or E, or if E is C-term to D or EChymotrypsin (C-term to F/Y/W/M/L, not before P, not after Y if P is C-term to Y)C-terminal side of F, L, M, W, Y if P is C-term to F, L, M, W, Y, if P is N-term to YChymotrypsin (C-term to F/Y/W/, not before P, not after Y if P is C-term to Y)C-terminal side of F, Y, W if P is C-term to F, Y, W, if P is N-term to YTrypsin/Chymotrypsin (C-term to K/R/F/Y/W, not before P, not after Y if P is C-term to Y)C-terminal side of K, R, F, Y, W if P is C-term to K, R, F, Y, W, if P is N-term to YPepsin (pH 1.3)C-terminal side of F, L Pepsin (pH > 2)C-terminal side of F, L, W, Y, A, E, Q proteinase KC-terminal side of A, F, Y, W, L, I, V

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If you know of any terms that have been omitted from this glossary that you feel would be useful to include, please send detail to the Editorial Office at GenScript: website@genscript.com

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