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Nuclear transfer

Nuclear transfer is a form of cloning. The steps involve removing the DNA from an oocyte (unfertilized egg) and injecting the nucleus, which contains the DNA to be cloned. Nuclear transfer is also the introduction of the nucleus from a cell into an enucleated egg cell (an egg cell with its own nucleus removed).

Nuclear transfer is now applied to many cases. In a laboratory procedure, a cell's nucleus is removed and placed into an oocyte with its own nucleus removed. Hence, the genetic information from the donor nucleus controls the resulting cell. Such cells can be induced to form embryos. This process was used to create the cloned sheep "Dolly". Furthermore, somatic cell nuclear transfer (SCNT), or “therapeutic cloning,” is a potentially powerful technique for generating autologous ESCs from adult somatic cells.

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If you know of any terms that have been omitted from this glossary that you feel would be useful to include, please send detail to the Editorial Office at GenScript: website@genscript.com

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