- REAGENT SERVICES Hot!
-
PRODUCTS
-
Most Popular Reagents
-
Instruments
-
Antibodies
-
ELISA Kits
-
Protein Electrophoresis and Blotting
-
Protein and Antibody Purification
-
Recombinant Proteins
-
Molecular Biology
-
Stable Cell Lines
-
Cell Isolation and Activation
-
IVD Raw Materials
-
Therapy Applications
-
Resources
-
![AmMag™ Quatro Automated Plasmid Purification]()
AmMag™ Quatro automated plasmid purification
-
![Anti-Camelid VHH]()
MonoRab™ Anti-VHH Antibodies
-
![ELISA Kits]()
ELISA Kits
-
![Precast Gels]()
SurePAGE™ Precast Gels
-
![Quatro ProAb Automated Protein and Antibody Purification System]()
AmMag™ Quatro ProAb Automated Protein and Antibody Purification System
-
![Target Proteins]()
Target Proteins
-
![AmMag™ Quatro Automated Plasmid Purification]()
AmMag™ Quatro automated plasmid purification
-
![Stable Cell Lines]()
Stable Cell Lines
-
![Cell Isolation and Activation]()
Cell Isolation and Activation
-
![Quick
Order]()
Quick Order
-
![Quick
Order]()
Quick Order
- APPLICATIONS
- RESOURCES
- ABOUT US
Transforming Medicine: The Potential of Endothelial Cilia Proteins as Groundbreaking Biomarkers
Cilia are microtubule-based organelles found in most cells in the body. Endothelial cilia are a known blood flow sensor and studies have identified that upon high shear stress, endothelial cilia get dismantled, a process called deciliation. On deciliation, proteins found inside a microtubule-based organelle called cilia are released into the blood. When these proteins from inside the cilium are spilled into blood, they stick to cells in blood, which can be detected by flow and immunoassays. These ciliary proteins can be observed in conditions where the underlying vasculature is weakened due to disturbed flow.
This webinar will explore the latest findings on cilia’s biomarker potential and its application in the clinic.
In this webinar, you will learn
The role of endothelial cilia as blood flow sensors and how the process of deciliation leads to the release of ciliary proteins into the bloodstream.The development of immunoassays and flow cytometry-based approaches for detecting ciliary proteins in human blood and other body fluids.How ciliary protein levels can help predict short and long-term patient outcomes.
Webinar Details
- Date: December 13th, 2024
- Time: 10:00 am EDT (NA) / 3:00pm BST (UK) / 4:00pm CEST (EU-Central)
Ramani Ramchandran, PhD
Professor, Medical College of Wisconsin
President and Founder, CIAN, IncProfessor Ramani Ramchandran completed his PhD in Biochemistry and Molecular Biology at Augusta University. He undertook a research fellowship at Harvard Medical School from 1997 to 2002. In 2002, upon receipt of National Cancer Institute Scholar Award, he moved to National Institutes of Health (NIH) to start his first independent lab. He was recruited to the Medical College of Wisconsin (MCW) in 2007 as an Associate Professor where he has risen through the academic ranks to the position of professor in the Department of Pediatrics, Children’s Research Institute. He has had numerous leadership positions at MCW including the current position of the Director of the Medical Student Summer Research Program. He has published over 100 articles and is considered a leading expert on vascular biology. His research has been continuously funded from NIH since 2002. In 2023, Professor Ramchandran founded CIAN Inc., a company dedicated to developing ciliary proteins as a biomarker for altered blood flow. He is active in both academic and industry related activities.
Speaker-related Webinars
Transforming Medicine: The Potential of Endothelial Cilia Proteins as Groundbreaking Biomarkers
Cilia are microtubule-based organelles found in most cells in the body. Endothelial cilia are a known blood flow sensor and studies have identified that upon high shear stress, endothelial cilia get dismantled, a process called deciliation.
-
