Webinars » Enhance productivity and purity in next-generation bispecific antibody manufacturing
Bispecific antibodies (BsAbs) are at the forefront of next-generation antibody therapies, offering immense potential but also posing significant production challenges, such as secretion inefficiencies, chain mispairing, and impurity formation.
In this webinar, we will introduce GenScript’s TurboCHO™ technology, which addresses these challenges through an integrated and iterative workflow that optimizes cell lines, vectors, and media using Design of Experiments (DOE) to fine-tune chain ratios and enhance yields.
This process is further supported by a streamlined yet customizable purification strategy that employs advanced chromatography techniques to selectively remove impurities based on molecular differences, ensuring superior product purity. We will also present real-world case studies demonstrating the effectiveness of this systematic approach in overcoming common BsAb production hurdles and supporting a wide range of formats—from early-stage development to clinical-scale manufacturing.
Senior Protein Scientist, GenScript Biotech
Dr. Heng Tai Liew is a Senior Protein Scientist at GenScript Biotech, specializing in the optimization and advancement of protein and antibody production processes to meet rigorous industrial standards. With extensive expertise in addressing complex challenges, he focuses on overcoming obstacles in the development of bi- and multi-specific antibodies. In addition to providing innovative technical solutions, Liew is a trusted resource for troubleshooting and offering strategic guidance on complex antibody-related projects.