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![Peptide Solubility Testing]( "Peptide Solubility Testing")
Overview
Performing experiments with hydrophobic peptides can be extremely frustrating if you are unsure of how to properly dissolve your peptide. Determining the optimal conditions for dissolution of your peptide can consume up to 5 mg of your custom peptide stock, depleting peptide that might be crucial for future experiments.
Our solubility testing service makes working with hydrophobic peptides easier by taking the guesswork out of peptide solubility. We provide you with a complete, customized dissolution profile of your peptide, including a report containing the gross peptide concentration of your peptide and the solvents your peptide dissolves in best. Our peptide solubility test is a unique solution to help you conserve time, money, and your peptide stock, allowing you to easily determine the condition that both dissolves your peptides to the highest concentration and suits your assay requirements.
Advantages of solubility testing
Saves your sample
no need to use your custom peptide stock
Saves your time
we prepare a customized dissolution profile for you
High success rate
at least 99% of peptides are dissolvable in one of our common lab solvents
Water: ~80-90% solubility
DPBS: ~80-90% solubility
DMSO: ~99% solubility
Solubility Testing Process and Deliverables
Qualitative solubility test Free
Your peptide sequence's characteristics are evaluated, and a customized solubility testing approach is designed.
Up to 3 of 6 solvents can be selected, default solvents are Ultrapure water, 1 x DPBS(pH 7.1±0.1) and DMSO.
General solubility property will be obtained (such as “soluble”, “insoluble”).
SolventResultsUltrapure waterInsoluble1 x DPBS
(pH 7.1 ± 0.1)SolubleDMSOFreely solubleQuantitative solubility test New
The solvent used for solubility test can be customized. .
You will received a customized solubility test report containing the specific concentration of your peptide in each of the tested solvents.
If the peptide doesn’t dissolved well in your customized solvents, we will offer another soluble protocol for free.
SolventResultsGross Peptide ConcentrationUltrapure waterUndissolvedN/A1 x DPBS
(pH 7.1 ± 0.1)Dissolved≤15mg/mLDMSODissolved≤20mg/mLNote:
- View your solubility test results any time by logging into your Account page.
- All the solubility test results are based on gross peptide weight (include peptide, salt, moisture and impurity etc..), please choose Peptide Content Analysis service for precise target peptide concentration.
- For quantitative solubility test, the default testing start at a maximum concentration of 20mg/mL, if you need higher concentration test please contact us for detail.
- Former free solubility test is upgraded into Qualitative solubility test and the upgrade is launched from 10/27/2022.
How to order
Crude peptides, desalt peptides and peptide libraries are not eligible for a free solubility test.
Place a quote by clicking，Get a Quote Now，or emailing peptide@genscript.com
Enter your desired sequence, purity and quantity and check Q to request a free
Review your quote at My Account and order online or bv email
Your peptide and customized solubility report will arrive by Fedex in 2-3 weeks (may vary depending on sequence, purity and quantity)
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