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48 Results

Synthetic Lethality Drugs for Cancer: WRN Helicase Inhibitors Show Promise in Early Studies | GenScript

Researchers are developing a new type of cancer treatment that targets a vulnerability in tumor cells called "synthetic lethality." This article explores a specific drug candidate, VVD-133214, which inhibits WRN helicase

May 30, 2024

Personalized Neoantigen Vaccines and Immune Checkpoint Inhibitors Show Promise in Hepatocellular Carcinoma | Genscript

May 22, 2024

Unlocking the Potential: The Rise of Keytruda and Tumor Vaccines in Cancer Treatment

Explore the synergy between Keytruda and tumor vaccines in cancer treatment. Discover how GNOS-PV02 and mRNA-4157/V940 are revolutionizing melanoma and hepatocellular carcinoma therapy. Delve into the groundbreaking research reshaping the landscape of on

Apr 27, 2024

Transgenesis Achieved Without Exogenous DNA: Harnessing Retroelement Proteins

Discover the groundbreaking PRINT technology developed by UC Berkeley, utilizing retroelement proteins for gene insertion.

Mar 18, 2024

New Approach Leverages Antibodies to Acid-Base Transporters in Breast Cancer

Scientists at Aarhus University, Denmark, led by Ebbe Boedtkjer, developed inhibitory anti-NBCn1 antibodies to directly dissect the role of this acid extrusion molecule in breast cancer, providing support for a new potentially effective strategy to target

Mar 18, 2024

Evaluating a New Immunotherapy Strategy: Targeting Solid Tumors with Recombinant Dimeric IgA Antibodies

KRASG12D-driven cancer models with positive PIGR expression and recombinant antibodies are used in these studies to elucidate the therapeutic potential of dimeric IgA antibody transcytosis, demonstrating their capacity to reach and expel relevant cytosoli

Feb 26, 2024

AI Empowers Oncology: Breakthrough Antigen Discoveries Herald a New Era in Cancer Therapy

Explore the transformative impact of AI-driven antigen discovery in cancer therapy, from breakthroughs to clinical applications, promising new treatments for patients worldwide.

Feb 26, 2024

Revolutionizing Gene Editing: Unleashing the Power of Glycosyltransferases with Advanced DAF-BEs

Explore the groundbreaking advancements in gene editing with glycosyltransferases, an innovative approach beyond deaminases. Discover the development of DAF-BEs, a transformative base editing system, and its superior variants, DAF-CBE2 and DAF-TBE2.

Jan 24, 2024

Research Digest